The invention relates to the technical field of electronic invoice service management, in particular to an electronic invoice security management service system based on cloud computing and cryptography. The electronic invoice security management service system based on the cloud computing and the cryptography adopts technologies of the cloud computing, big data, anti-fake encryption, internet and mobile internet to ensure the correct generation, reliable storage, safety and uniqueness of electronic invoices, and provides convenient query authentication and other electronic invoice data services. The system can ensure the correct generation, reliable storage, query authentication, safety and uniqueness of electronic invoice information, realizes paperless, electronic, networked and automatic management of invoices, reduces the invoice cost and improves the informatization management level.