102 results about "Mouth rinse" patented technology

Peptides that bind with high affinity to oral cavity surfaces, such as tooth enamel, have been discovered. The peptides exhibit antibacterial and mineralizing abilities, and are useful in many aspects of oral care. The peptides include the amino acid sequence AKRHHGYKRKFH-SpSp. The peptides can be included in oral care compositions such as toothpastes and mouthwashes. The oral care compositions can be used in methods to treat or prevent diseases or conditions induced by acidophilic oral bacteria. Exemplary methods include reducing or preventing tooth decay or demineralization, biofilm or dental plaque formation, and / or bacterial adhesion to a tooth surface; and promoting mineralization of teeth surfaces.

Disclosed herein are oral care compositions, such as mouthwash or mouth rinse compositions, comprising at least a plant-based amine chloride and at least a flavorant. Methods for manufacturing and methods of using the oral care compositions are also disclosed herein.

The invention discloses an FLG gene and protein detection method based on oral cell non-invasive sampling, which comprises the following steps: Step 1: sample collection: collecting oral cells through mouth rinsing of a subject; step2: RNA extraction and gene expression analysis: extracting oral cell total RNA in the oral cells in the step 1 by using a Trizol reagent, and analyzing FLG gene expression through qRT-PCR (Quantitative Reverse Transcription-Polymerase Chain Reaction); 3, protein extraction and immunoblotting analysis are conducted, specifically, protein is extracted from the oral cells in the step 1 through an SDS lysis buffer solution, and FLG protein expression is detected through the Western blot technology. According to the present invention, the subject rinses the mouth and collects the oral cavity cells, such that the convenient, non-invasive and efficient sample collection is achieved.

A complex consisting of lipoic acid or a salt thereof, a chelating agent such as a salt of ethylene diamine tetraacetic acid (EDTA) or analogous compounds and an ester of ascorbic acid with long-chain fatty acids, in particular ascorbyl palmitate inhibits the pigmentation of teeth induced by chlorhexidine and salts thereof. In addition to the depigmenting complex, the formulations of the invention, in the form of gels, mouthwashes, toothpastes or periodontal sprays, may contain other ingredients such as hyaluronic acid or hyaluronates, glycerophosphocholine, sweeteners, flavourings, buffering agents, viscosifying agents, mucoadhesive and filming agents, solvents, co-solvents, surfactants.

The invention discloses demineralized dentin remineralization mouthwash based on cp20k-p3 bionic polypeptide and an application of the demineralized dentin remineralization mouthwash. The mouthwash is prepared by mixing the polypeptide cp20k-p3 (the amino acid sequence is CNQKHPCWRRHGKKHRGLHRKFHGNACNC) derived from barnacle mucin 20K, an aqueous solution of calcium salt and an aqueous solution of phosphate. The polypeptide can specifically recognize and adsorb an organic matrix exposed on the surface of demineralized dentin, guide hydroxyapatite crystals to directionally deposit on the demineralized part of the dentin, and form a compact mineralized layer similar to a natural structure on the surface of the dentin. Compared with a calcium phosphate mixed aqueous solution without cp20k-p3, the preparation method is simple and convenient to operate, can form a compact mineralized layer with the surface of the re-demineralized dentin, and has excellent stability in an oral environment.

The invention discloses mouthwash for treating oral ulcer caused by chemoradiotherapy, which is mainly prepared from the following raw materials in percentage by weight: 0.15 percent to 0.25 percent of chlorhexidine gluconate, 0.015 percent to 0.025 percent of polypeptide of which the amino acid sequence is RWRWRW, 0.05 percent to 0.15 percent of sodium hyaluronate, 0.05 percent to 0.15 percent of menthol, 2.8 percent to 3.2 percent of humectant, 0.45 percent to 0.55 percent of sodium ascorbyl phosphate, 0.5 percent to 1 percent of sodium bicarbonate and the balance of distilled water. The mouthwash for treating the oral ulcer caused by the chemoradiotherapy not only has antibacterial and moisturizing functions, but also can relieve the pain degree of the oral ulcer caused by the chemoradiotherapy, reduce the infection risk and promote ulcer healing, the technical problem that an existing product is single in function is solved, a patient does not need to alternately use multiple preparations, and the compliance is high.

The invention discloses a biological material with an efficient peculiar smell removal function, which is prepared from the following raw material components in parts by mass: 8 to 12 parts of manganese precursor, 0.8 to 1.2 parts of soluble metal salt, 4000 to 5000 parts of dispersing agent and 90 to 100 parts of conditioning agent. The composite nano material which takes small-particle-size thorn convex manganese dioxide as a core and loads metal ions is prepared by simple processes such as mixing, reaction, centrifugation and the like. The material can efficiently remove bad breath through a dual synergistic mechanism; small-particle-size manganese dioxide captures odor-producing bacteria through physical adsorption; meanwhile, released metal ions and hydrogen sulfide are subjected to chemical reaction to generate substances difficult to volatilize. Through the synergistic effect of physical interception and chemical conversion, the dual effects of blocking generation of peculiar smell from the source and immediately eliminating the peculiar smell are achieved. The product disclosed by the invention has biocompatibility and a long-acting peculiar smell removal function, can be widely applied to oral care products such as toothpaste and mouth wash, and provides an innovative solution for solving the problem of bad breath.

The utility model relates to the technical field of gargling equipment, and discloses water pressure adjustable oral gargling equipment which comprises a device shell, a groove is formed in one side of the surface of the device shell, a prompting mechanism is fixedly arranged in the groove, and a device bottom plate is fixedly arranged at the bottom end of the device shell. A plurality of limiting grooves are fixedly formed in the top end of the device bottom plate, first springs are fixedly arranged in the limiting grooves, a pressing plate is fixedly arranged at the top ends of the first springs, a water outlet mechanism is fixedly arranged at the top end of the pressing plate, and an adjusting mechanism is fixedly arranged at the top end of the water outlet mechanism and comprises a connecting pipe. A sliding groove is formed in one side of the interior of the connecting pipe, and a sliding block is slidably connected into the sliding groove. According to the utility model, the water outlet mechanism, the adjusting mechanism, the prompting mechanism and the pressing plate are arranged, so that the water pressure is effectively and conveniently adjusted, and the function of prompting the equipment that the mouth wash is insufficient is added.

The invention discloses an oral care composition with antibacterial and senile dementia prevention effects, which comprises the following raw materials: berberis poiretii schneid extract and folium eriobotryae extract, and the dosage ratio of the berberis poiretii schneid extract to the folium eriobotryae extract is (10: 1)-(1: 10). The berberis poiretii schneid extract and the folium eriobotryae extract in a proper proportion are selected to be compounded and combined, it is found that the obtained composition has the effect of preventing senile dementia and also has the effects of synergistic interaction, bacteriostasis and oral ulcer prevention and treatment, and the bacteriostatic effect is far better than that of single berberis poiretii schneid extract; on the basis, a series of oral care products with marketization potential are developed, and the oral care products are safe and free of side effects, so that middle-aged and elderly people can clean gingiva, prevent and treat oral ulcer and prevent or delay senile dementia in daily oral care behaviors such as tooth brushing and mouth rinsing, and the oral care products are safe and free of side effects. The product is an excellent daily necessity beneficial to the public for early prevention of senile dementia, and has a considerable application prospect.

The traditional Chinese medicine mouthwash comprises a traditional Chinese medicine compound and a mouthwash matrix, and the traditional Chinese medicine compound comprises the following components in parts by weight: 10-20 parts of golden cypress, 15-30 parts of angelica sinensis, 15-30 parts of honeysuckle, 15-30 parts of chrysanthemum and 15-30 parts of liquorice. The invention also provides a preparation method of the traditional Chinese medicine mouthwash for relieving gingivitis. The traditional Chinese medicine mouthwash for relieving gingivitis can promote proliferation of gingival fibroblasts, promote secretion of gingival fibroblast collagen and effectively inhibit proliferation of oral anaerobic bacteria, thereby relieving gingivitis.

The invention discloses an ionic liquid anti-caries coating with dual functions of bacteriostasis and mineralization promotion and a preparation method thereof, belongs to the technical field of dental caries prevention in stomatology, and aims to overcome the defects that an existing anti-caries material fluoride is insufficient in bacteriostasis effect and relatively short in residence time on a tooth surface. And the risk of oral flora imbalance caused by the generation of drug resistance possibly caused by antibacterial mouthwash is also caused. According to the invention, alkyl imidazole is taken as a main body, is paired with ions such as strontium and fluorine with a mineralization promoting function, is modified by a silane coupling agent, and is properly added with an excipient, so that the constructed ionic liquid coating can be adhered to the surfaces of teeth for a long time, the dual effects of bacteriostasis and mineralization promoting can be durably exerted, and a more excellent anti-caries effect can be realized.

To search for a new active ingredient that is effective in improvement, treatment, and prevention of periodontal disease, and to provide a periodontal disease preventive or therapeutic agent including the new active ingredient.SOLUTION: A periodontal disease preventive or therapeutic agent containing dextromethorphan and / or a salt thereof, an internal or external periodontal disease preventive or therapeutic medicine, and an oral composition for preventing or treating periodontal disease such as a patch, a liniment, a film, a dentifrice, a mouthwash, or a spray, are provided. As the salt of dextromethorphan, dextromethorphan hydrobromide is preferred.SELECTED DRAWING: Figure 2

Oral care compositions and, particularly, mouthwashes and concentrated mouthwashes are disclosed herein. In accordance with an aspect of the invention, provided is a concentrated mouthwash composition comprising from about 60 to about 85 wt.% of polyol; from about 11 to about 30 wt.% of water; optionally, an amino acid comprising arginine, lysine, a salt thereof or a combination of two or more thereof; and from about 1 to about 10 wt.% of nonionic surfactant, wherein all weight percentages are based on the total weight of the concentrated mouthwash composition.

To provide a toothpaste and an oral hygiene product for oral cavity, mouth rinsing, nasal cavity, or throat that achieve reduction of proliferation of influenza virus and exert an inactivation effect.SOLUTION: A toothpaste and an oral hygiene product for oral cavity, mouth rinsing, nasal cavity, or throat, which use kombu powder as an active ingredient, are used by remaining in oral cavity, nasal cavity, or throat for at least 15 seconds in order to reduce proliferation of influenza virus and exert an inactivation effect, and contain, in physiological saline or boiling water thereof, kombu powder having a particle diameter of 5 μm at a weight ratio of 2%.SELECTED DRAWING: Figure 7

The invention relates to mouthwash for promoting postoperative wound healing and a preparation method thereof, and belongs to the technical field of oral care. The invention discloses mouthwash for promoting postoperative wound healing. Comprising 0.5%-2% of a green tea extract, 0.5%-1.5% of a centella asiatica extract, 0.1%-0.5% of a mint extract, 0.1%-0.5% of a lotus leaf extract, 0.1%-0.5% of a spanishneedles herb extract, 5%-15% of a humectant, 0.1%-1% of arginine, 0.1%-1% of a sweetening agent, 0.001%-0.1% of recombinant human epidermal growth factors and the balance of water. The mouthwash is prepared from natural, safe and non-irritant components, so that oral bacteria can be effectively inhibited, and wound healing can be promoted; stability is good, taste is comfortable, and long-term use by patients is facilitated; the oral care solution is expected to be provided for postoperative patients with better quality and more effective oral care solutions, and wound healing and oral health recovery are assisted.

The invention discloses traditional Chinese medicine compound mouthwash as well as a preparation method and application thereof. The traditional Chinese medicine compound mouthwash comprises the following medicinal materials in parts by weight: 35-60 parts of pine nodular branch, 10-30 parts of white mulberry root-bark, 10-30 parts of cortex lycii radicis, 10-30 parts of lalang grass rhizome and 1-15 parts of mint. The traditional Chinese medicine compound mouthwash is used for treating oral ulcer, swelling and aching of gum, throat pain and the like caused by excess heat or asthenic fire flaming.

The invention relates to natural plant extract antibacterial mouthwash and a preparation method thereof, and belongs to the technical field of mouthwash. The mouthwash takes water as a solvent and is composed of natural plant extracts and auxiliary functional auxiliaries, the natural plant extracts comprise honeysuckle flower, liquorice and tea leaf extracts, and the mouthwash is natural and safe, can effectively inhibit bacteria and overcomes the defects of traditional chemical mouthwash. Meanwhile, the natural plant extract is modified by the casein phosphopeptide and the tannic acid, the tannic acid is cross-linked with the casein phosphopeptide and the natural plant extract through phenolic hydroxyl groups to form a stable compound, and the casein phosphopeptide is combined with calcium ions in oral mucosa or enamel, so that the residence time of the natural plant extract in the oral cavity is prolonged, and the oral cavity health care effect is improved. Therefore, the antibacterial effect of the mouthwash is improved.

The problem to be solved by the present invention is to provide a substance for preventing, treating or improving periodontal diseases.SOLUTION: Provided are a pharmaceutical composition for preventing and treating periodontal diseases comprising a Alnus plant extract as an active ingredient, a food composition for improving periodontal diseases comprising the same, and a toothpaste or mouthwash composition and a feed comprising the same, wherein the Alnus plant extract according to the present invention comprises oregonin or aglycoform thereof and has excellent effects of improving, preventing and treating periodontal diseases.SELECTED DRAWING: Figure 1

1. Name of the designed product: square bottle for toothpaste (mouthwash). 2. Use of the designed product: for containing liquid. 3. Design points of the designed product: in shape. 4. Picture or photo best indicating the design points: perspective view.

The utility model relates to the technical field of mouth wash distribution, and discloses an oral mouth wash distribution device which comprises a working table and supporting legs fixedly installed at the positions, close to the four corners, of the bottom of the working table. A plurality of fixing grooves are fixedly formed in the position, close to the edge, of the top of the containing disc at equal intervals, and distribution tanks are attached to the bottoms of inner cavities of the fixing grooves correspondingly. A circular base, a movable gear, a disc, a rotating rod, a vertical plate, a pawl, a telescopic spring, a movable rack plate, a movable block, a threaded rod, a driven bevel gear and a driving bevel gear are matched with one another; according to the device, the adjusting plate can move upwards to drive the placing disc to rotate, so that the next distribution tank can be filled when the adjusting plate moves downwards to restore, a worker does not need to rotate, distribution is not affected by placing and taking of the worker, the distribution efficiency is high, and the using effect of the device is improved.

The invention relates to traditional Chinese medicine mouthwash and a preparation method thereof. The traditional Chinese medicine mouthwash is prepared from the following raw materials in parts by weight: 35-40 parts of traditional Chinese medicine leach liquor; 18 to 22 parts by weight of honeysuckle flower; 8-12 parts by weight of folium isatidis; 10 to 14 parts by weight of mint; 18-22 parts by weight of green tea; and 600 to 1200 parts by weight of purified water. The invention provides the traditional Chinese medicine mouthwash which has the effects of preventing decayed teeth, inhibiting bacteria, diminishing inflammation and freshening breath, is safe and non-toxic, is simple to produce and is low in irritation and stable by utilizing respective effects and synergistic effects of the medicines.

The utility model discloses an electrolysis type gargling machine which comprises a shell and a surface cover, a supporting bottom plate is fixed on the bottom surface of the shell, and an electrolyte box, an electrolysis box, a gargling water pump, a tooth washing water pump, an electromagnetic valve and an electrolysis circulating water pump are fixed in the shell; a water inlet, a gargling water outlet, a tooth washing water outlet and an alkaline liquid water outlet are formed in the supporting bottom plate; a control circuit board is fixed in the shell; the top of the electrolyte tank is communicated with the electrolysis tank through an electrolysis circulating water pump, and an acidic water outlet of the electrolysis tank is communicated with the electrolyte tank through a water guide pipe; and the bottom end of the electrolyte tank is connected with the water inlet through an electromagnetic valve. According to the utility model, the structural arrangement is reasonable, the electrolyte tank is connected with the electrolysis tank through the electrolysis circulating water pump, acidic liquid is generated through electrolysis and flows back to the electrolyte tank for temporary storage, and gargling water outlet and tooth washing water outlet operations are realized through the gargling water pump or the tooth washing water pump, so that the sterilization effect and the use safety are improved; and the applicability and the practicability are high.

The invention relates to the technical field of gargle, in particular to a three-leaf heart-purging gargle and a preparation process thereof, and the three-leaf heart-purging gargle is prepared from the following raw materials in parts by weight: 24-36 parts of a basic heat-clearing system; the basic heat clearing system is prepared from the following components in parts by mass: 17-23 parts of radix scutellariae and 17-23 parts of radix et rhizoma rhei; 7 to 13 parts of rheum officinale; 12 to 18 parts of a synergistic anti-inflammatory agent; 9-15 parts of a mucous membrane repairing agent; 0.3 to 0.8 part of a cool and refreshing soothing agent; and 55.1 to 69 parts of an auxiliary additive. The three-leaf heart-purging mouthwash takes natural traditional Chinese medicinal materials such as scutellaria baicalensis and tetrastigma hemsleyanum as core components, avoids side effects of tooth staining, taste change and mucosal lesion caused by chemical antibacterial agents, reduces dependence on preservatives and irritation to the oral cavity through scientific proportioning and process optimization, is suitable for long-term use, and has a good market prospect. The mouthwash is especially suitable for people sensitive to chemical components, and various defects of traditional mouthwash are overcome.

The utility model is applicable to the technical field of oral care, and provides a portable gargling device which comprises two placing bottles, the two placing bottles are in threaded connection with each other, and the two placing bottles are respectively used for placing gargling water and clear water; the two sealing covers are respectively mounted on the two placing bottles in a threaded manner; the first water pump is fixedly mounted on the sealing cover; the first water inlet pipe is fixedly arranged on the placing bottle, and the first water inlet pipe is communicated with the water inlet end of the first water pump; the gargling pipe is fixedly mounted on the sealing cover, and the gargling pipe is communicated with the water outlet end of the first water pump; and the nursing mechanism is assembled on the placing bottle and is used for nursing the oral cavity of the user. The portable gargling device provided by the scheme is relatively convenient to carry, facilitates gargling of a user, can help the user brush teeth, better meets different requirements of the user, and is relatively flexible to use.

The invention discloses ozonized oil and fructus forsythiae composite micro-capsules and a preparation method thereof, and mouthwash for antibacterial repair and a preparation method thereof. The mouthwash comprises the following components: 1-5 wt% of ozonized oil and fructus forsythiae composite micro-capsules, 0.5-2 wt% of carboxymethyl cellulose sodium, 0.1-1 wt% of a sweetening agent, 0.05-0.5 wt% of menthol, 0.1-0.3 wt% of sodium benzoate and the balance of deionized water. The ozonized oil and fructus forsythiae composite microcapsule comprises the following components: 5-15 wt% of ozonized oil, 5-15 wt% of fructus forsythiae, 10-25 wt% of gelatin, 5-15 wt% of Arabic gum and the balance of deionized water. Ozonized oil with strong oxidizing property and fructus forsythiae rich in various antibacterial components are combined, so that complementary advantages of natural components are realized, the antibacterial spectrum is expanded, and the occurrence of allergic phenomena is reduced; the fructus forsythiae and the ozonized oil exist in a micro-capsule form, so that the stability of the ozonized oil is improved, the taste of the ozonized oil is covered, the mouth feel and the smell of the traditional Chinese medicine mouth wash are improved, meanwhile, a protective film can be formed on the surface of an oral mucosa, the dryness of the oral cavity is relieved, the comfort and the compliance in use are improved, and the acceptability of a user is improved.

A liquid mixing and dispensing device (2) and a mouthwash oral irrigator (1), which alleviate the problems of large volume and unstable operation of the liquid mixing and dispensing device (2). The liquid mixing and dispensing device (2) comprises a mixing pump (23), a first delivery pipe (21), a second delivery pipe (22), a raw liquid pump (24), a drive unit (25), a first transmission assembly (26) and a speed-reduction transmission assembly (27), wherein the mixing pump (23) has a liquid outlet (230), and the first delivery pipe (21) and the second delivery pipe (22) are both in communication with the mixing pump (23); the raw liquid pump (24) is connected to the second delivery pipe (22), and is configured to pump a material in the second delivery pipe (22) to the mixing pump (23); the first transmission assembly (26) and the speed-reduction transmission assembly (27) are both connected to the drive unit (25) and are arranged on the same side of the drive unit (25); and the first transmission assembly (26) is connected to the mixing pump (23), the speed-reduction transmission assembly (27) is connected to the raw liquid pump (24), and the transmission ratio of the speed-reduction transmission assembly (27) is greater than the transmission ratio of the first transmission assembly (26).

The invention relates to an oral care microcapsule and a preparation method thereof, and belongs to the technical field of oral care products. The microcapsule is prepared from a wall material and a core material through a microencapsulation technology, wherein the wall material contains at least two compounded celluloses, sugar alcohols and a compound plant extract compounded from a platycladus orientalis extract, an oat extract and an apple fruit extract; and the core material contains a compound enzyme compounded by papain, lysozyme and glucanase, and a compound plant fermentation extract prepared by fermenting radix morindae officinalis and angelica sinensis. A spray drying method is adopted for preparation, and the product is obtained through core material and wall material solution preparation, emulsification and drying. Through the synergistic effect of the wall material and the core material, the enzyme can be stably preserved for a long time, yellowing is inhibited, antibacterial and antioxidant effects are enhanced, the preparation is simple and convenient, industrialization is easy, and the enzyme can be applied to products such as toothpaste and mouth wash.

The invention discloses an oral composition containing polysaccharide-based cinnamon oil antibacterial Pickering emulsion and a preparation method thereof, and belongs to the technical field of oral care products. The composition comprises Pickering emulsion and an orally acceptable carrier, wherein the Pickering emulsion takes cinnamon oil as a dispersion phase and polysaccharide-based solid particles as a stable phase, and the content of the Pickering emulsion is 20-60%; the polysaccharide-based solid particles are preferably chitosan nano-particles of which the surfaces are modified in situ by polydopamine, the emulsion is prepared by high-speed shearing and emulsifying, and the composition can be prepared into toothpaste and mouth wash. The Pickering emulsion is constructed through polysaccharide-based particles, the problem that cinnamon oil is easy to volatilize and degrade is solved, polydopamine in-situ modification endows the emulsion with excellent oral adhesion and retention capacity, saliva scouring and pH fluctuation can be resisted, and the long-acting effect of the cinnamon oil is achieved; meanwhile, the synergistic antibacterial and anti-biofilm effect of the polysaccharide-based particles, the cinnamon oil and the polydopamine is achieved, the preparation process is simple, the method is matched with an existing oral care product production system, and safety and industrialization feasibility are excellent.

The invention relates to the technical field of oral care products, in particular to a composition for dental plaque color development, an oral care product and a preparation method and application of the oral care product. According to the scheme, the composition for dental plaque color development comprises the red pigment and the PVM / MA copolymer, the red pigment and the PVM / MA copolymer are combined to be used for preparing oral care products, and the dental plaque dyeing effect of toothpaste containing a color developing agent is improved in the aspect of dental plaque color development; the technical problem that in the prior art, an oral care product with an ideal dental plaque developing effect and an ideal cleaning effect is lacked is solved. The composition of the scheme is applied to oral care products including toothpaste, and the enrichment of the bacterial plaque developing pigment on the bacterial plaque can be promoted and the bacterial plaque developing effect can be enhanced through the operations of tooth brushing, mouth rinsing, tooth brushing and the like. The oral care product containing the composition disclosed by the invention not only can help a user to effectively clean the oral cavity, but also has enhanced effects of preventing and removing dental plaque, and has a good application prospect.

The present invention relates to an emulsifier, an emulsification composition, an oral cleansing agent, and an oral cleansing composition, each comprising at least one of theaflavin and thearubigin. The present invention also relates to an emulsification method and an oral cleansing method, each using at least one of theaflavin and thearubigin.