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9 results about "Nootkatone" patented technology

Nootkatone is a natural organic compound and is the most important and expensive aromatic of grapefruit. It is a sesquiterpene and a ketone. Nootkatone was previously thought to be one of the main chemical components of the smell and flavour of grapefruits. In high purity, it is usually found as colorless crystals. Crude extractives are liquid, viscous and yellow. Nootkatone is typically extracted from grapefruit, but can also be manufactured with genetically modified organisms, or through the chemical or biochemical oxidation of valencene. It is also found in Alaska yellow cedar trees and vetiver grass.

Method for detecting content of volatile substances in aquilaria sinensis

According to the method for detecting the content of the volatile substances in the aquilaria sinensis, provided by the invention, through pretreatment steps such as extraction of an extraction solvent, heating reflux and filtration, a sample is selectively and preliminarily purified, and the matrix effect of subsequent detection and analysis is effectively reduced; an inert capillary column is used for separation, high-purity helium is used as carrier gas, and an optimized heating program and an MRM detection mode are combined; through the synergistic effect of the two components, comprehensive, accurate and high-repeatability qualitative and quantitative analysis of various volatile substances in the aquilaria sinensis, especially nookatone which is easy to leak in a conventional method, is realized, and a reliable technical means is provided for accurate identification and quality evaluation of the aquilaria sinensis.
Owner:DONGGUAN FOOD & DRUG INSPECTION INSTITUTE (DONGGUAN FOOD INSPECTION CENTER DONGGUAN FOOD & DRUG EVALUATION & CERTIFICATION CENTER)

Masking agent

An agent containing at least one aroma compound selected from the group consisting of E-beta-damascone, S-(2-methyl-3-furyl)ethanethioate, beta-caryophyllene oxide, beta-ionone, 2,5-dihydroxy-1,4-dithiane, methyl anthranilate, S-furfuryl thioformate, 1-isothiocyanate-3-(methylthio)propane, nootkatone, 1,4-dioxacycloheptadecane-5,17-dione, sclareol, and sclareolide is effective for masking an unpleasant smell and for making oral products in which an unpleasant smell is masked.
Owner:AJINOMOTO CO INC

Brucella capable of converting varenishene to generate noottanone, application of Brucella, perfume containing noottanone and preparation method of perfume

The invention relates to a Brucella strain capable of converting Varnishene to generate noottanone, an application of the Brucella strain, a perfume containing noottanone and a preparation method of the perfume, and belongs to the technical field of microorganisms. The Brucella is preserved in the China Center for Type Culture Collection on July 11, 2025, and the preservation number of the Brucella is CCTCC M 20251582. According to the present invention, it is found that 0.6 g / L of Fe < 2 + >, 0.8% (v / v) of DMSO and 920 mg / L of vicenthene are added to an LB culture medium, vicenthene can be efficiently converted into noottanone by using Brucella intermedia HNGD-JT1, and the noottanone yield is 245.32 + / -14.37 mg / L.
Owner:HENAN UNIVERSITY OF TECHNOLOGY

Application of nootkatone as nilaparvata lugens attractant and attractant

ActiveCN122004215ABiocidePest attractantsRice plantsBrown planthopper
The invention belongs to the technical field of pest control, and relates to an application of nootkatone as a rice brown planthopper attractant and the rice brown planthopper attractant. The attractant is a solution containing nootkatone effective components, and nootkatone is a natural component and is green and safe. According to the application of the nootkatone as the nilaparvata lugens attractant, the attractant can be directly sprayed on rice plants, and the nootkatone is released by utilizing the lure after the nootkatone is volatilized or loaded on a slow-release carrier to prepare the lure, so that the nilaparvata lugens are attracted. Verification shows that nootkatone can be used as a'luring trap 'for green prevention and control of brown planthoppers, the egg laying amount and the feeding amount of female adults are reduced by luring the brown planthoppers, a good prevention effect is achieved, and a new direction is provided for green prevention and control of the brown planthoppers.
Owner:ZHEJIANG FORESTRY UNIVERSITY

Fractionation refining method of alpinia oxyphylla essential oil and application thereof

PendingCN121518220AEssential-oils/perfumesChemical compoundFractionation
The invention belongs to the field of alpinia oxyphylla essential oil fractionation and chemical components, and particularly relates to an alpinia oxyphylla essential oil fractionation refining method and application thereof. The fructus alpiniae oxyphyllae essential oil is divided into seven fractions through 6 fractionation, and in a light phase 6 and a heavy phase 6, the main active ingredient nootkatone (nootkatone) of fructus alpiniae oxyphyllae is enriched. The chemical components of the fractions are further analyzed, and the result shows that the chemical components, tastes, colors and the like of the seven fractions obtained through fractionation are obviously different, and the biological activities of compounds contained in the fractions are different. The method for fractionating and refining the alpinia oxyphylla essential oil can finely fractionate the alpinia oxyphylla essential oil, lays a foundation for research on pharmacological activity and development and utilization of the alpinia oxyphylla essential oil, provides a method for analyzing chemical components of seven fractions, and provides a foundation for comprehensive development and utilization of the alpinia oxyphylla essential oil.
Owner:TROPICAL CORP STRAIN RESOURCE INST CHINESE ACAD OF TROPICAL AGRI SCI

Agent and method for improving flavor of oats-containing food / beverage

PCT designated stageWO2026023456A1Food scienceBiotechnologyHexanal
The present invention relates to: an agent for improving the flavor of an oats-containing food / beverage, said agent containing, as an active ingredient, one or more selected from the group consisting of cinnamyl cinnamate, nootkatone, 5-methyl-2-phenyl-2-hexanal, caryophyllene oxide, cinnamaldehyde, 15-pentadecanolide, 3-l-menthoxypropane-1,2-diol, and l-menthyl-3-hydroxybutyrate; and a method for improving the flavor of an oats-containing food / beverage, said method comprising adding or blending the aforementioned agent to an oats-containing food / beverage.
Owner:TAKASAGO INTERNATIONAL CORP

Nootkatone for the treatment of pruritus

The present disclosure generally relates to compounds, compositions, and methods for treating pruritus using a therapeutically effective amount of nootkatone, a pharmaceutically acceptable salt, or a derivative thereof. Methods of formulating and using the compositions are also provided. Provided herein are methods of treating pain in a subject in need thereof. The methods include administering a therapeutically effective amount of nootkatone, a pharmaceutically acceptable salt, or a derivative thereof to the subject. In some embodiments, the compositions have less than about 5% (w / w) of other components naturally present in nootkatone-containing sources. In other embodiments, the nootkatone in the compositions has a purity of at least about 95% (w / w). In some variations, the compositions comprise nootkatone.
Owner:エンヴェダ セラピューティクス インコーポレイテッド

Valencene oxidase mutants and their use in preparing nootkatone

ActiveCN116103249BNaringinNucleotide
This invention discloses a Valenciane oxidase mutant and its application in the preparation of naringin. The invention constructs a gene library of the HPO mutant using site-directed mutagenesis. In vitro catalytic experiments using resting cells show that, under the same conditions, the optimal HPO mutant (HPO_G302G-V480A-V482A-A484A, whose amino acid sequence is shown in SEQ ID No. 4 and nucleotide sequence in SEQ ID No. 5) exhibits a catalytic efficiency 2.54 times that of the wild type, thereby increasing substrate utilization efficiency and improving the yield of the target compound, naringin. Furthermore, the bio-preparation method for naringin described in this invention is simple to operate, environmentally friendly, and uses mild reaction conditions, showing great application potential. In addition, this invention is the first report of successfully constructing a beneficial HPO mutant for high-yield naringin production.
Owner:SOUTH CHINA UNIV OF TECH

Use of oxidoreductase and mutant thereof in biosynthesis of nootkatone

PendingEP4450631A4FungiMicroorganism based processesOxidoreductaseBiochemistry
Provided is the use of oxidoreductase and a mutant thereof in the biosynthesis of nootkatone. The oxidoreductase is derived from Wickerhamomyces anomalus M15 and has a high ability to convert nootkatol, and an oxidoreductase mutant having a higher ability is obtained by means of site-directed mutation. Compared with the existing oxidoreductase that is capable of catalyzing nootkatol, the oxidoreductase and the mutant thereof have a good substrate tolerance, a high conversion rate and a high salt tolerance, provide conditions for the synthesis of nootkatone using an enzyme catalytic method in vitro, and achieve the synthesis of nootkatone by means of catalyzing nootkatol in an environmentally-friendly and efficient manner.
Owner:TERPIOT (GUANGZHOU) BIOTECHNOLOGY CO LTD