18 results about "Alpinia oxyphylla" patented technology

This invention provides a plant composition, its preparation method, and its application, relating to the field of plant essential oil technology. The plant essential oils extracted from Alpinia oxyphylla, Agrimonia pilosa, coriander seeds, and Hibiscus syriacus bark have excellent inhibitory effects against Malassezia; they are also non-irritating to human skin and can be used in daily chemical hair care product formulations to effectively inhibit dandruff.

The invention belongs to the field of gout prevention and treatment, and particularly relates to alpinia oxyphylla and turmeric tabletted sweets as well as a preparation method and application thereof. According to the alpinia oxyphylla and turmeric composition disclosed by the invention, alpinia oxyphylla and turmeric are taken as main components, the beautiful millettia root, the poria cocos, the kudzuvine root, the lithocarpus litseifolius, the purslane, the cassia seed, the black pepper and the dandelion are reasonably combined, and all the components are synergistically interacted, so that the prepared composition can remarkably improve the xanthine oxidase inhibition activity, can effectively relieve gout symptoms, and can be used for treating gout. The composition can be used for adjuvant therapy of gout patients. The tablet candy prepared by adding a sweetening agent into the alpinia oxyphylla turmeric composition disclosed by the invention is simple in preparation process, can be eaten for a long time as an auxiliary food in a gout treatment process, and has a great promoting effect on relieving gout symptoms.

This invention discloses a traditional Chinese medicine formula for preventing and treating feline urinary tract diseases, its preparation method, and its application. The formula consists of the following components in parts by weight: 15-25 parts of Psoralea corylifolia, 15-25 parts of Alpinia oxyphylla, 10-20 parts of Trigonella foenum-graecum, 5-15 parts of Zea mays, 5-15 parts of Juncus effusus, 10-20 parts of Dioscorea hypoglauca, 10-20 parts of Phellodendron chinense, 10-20 parts of Lonicera japonica, 5-15 parts of Paeonia lactiflora, and 5-15 parts of Glycyrrhiza uralensis. The traditional Chinese medicine formula provided by this invention has diuretic and urinary tract mucosal repairing effects. It can effectively relieve symptoms such as urinary stones, painful urination, hematuria, or gravel in the urine caused by damp-heat in the lower abdomen. It promotes the repair of the urinary tract mucosa in animals with urinary tract diseases, alleviates inflammatory responses, and prevents the formation of crystals in the urine.

The invention discloses a synthetic method of alpinia oxyphylla dipeptide, which comprises the following steps: coupling Fmoc-Ile-OH with H-Acp-NH2, washing, purifying and drying to obtain Fmoc-Ile-Acp-NH2, and removing Fmoc protection by using organic alkali to obtain H-Ile-Acp-NH2; fmoc-Tyr (tBu)-OH and H-Ile-Acp-NH2 are subjected to coupling, then Fmoc-Tyr (tBu)-OH and H-Ile-Acp-NH2 are subjected to washing, purification and drying, Fmoc-Tyr (tBu)-Ile-Acp-NH2 is obtained, organic alkali is adopted for Fmoc protection removal, and H-Tyr (tBu)-Ile-Acp-NH2 is obtained; the preparation method comprises the following steps: carrying out a coupling reaction on hexanoic acid and H-Tyr (tBu)-Ile-Acp-NH2, carrying out washing, purification and drying to obtain Hexanoyl-Tyr (tBu)-Ile-Acp-NH2, cracking a protecting group tBu of the Hexanoyl-Tyr (tBu)-Ile-Acp-NH2 by adopting a Lewis acid system, and carrying out sedimentation to obtain a crude product of alpinia oxyphylla dipeptide; and finally, recrystallizing in a composite liquid composed of an ionic liquid, and drying to obtain the high-quality alpinia oxyphylla dipeptide. The synthetic method provided by the invention can be suitable for industrial application, and the alpinia oxyphylla dipeptide product is high in yield and high in purity.

The invention provides a preparation method and application of alpinia oxyphylla leaf essential oil, and relates to the field of natural plant extracts. The alpinia oxyphylla leaf essential oil is applied to preparation of a bacteriostatic agent for inhibiting bacteria or / and fungi, and the bacteria comprise one or more of klebsiella pneumoniae, salmonella enterobacter and shigella flexneri. The fungi comprise one or more of candida tropicalis and malassezia furfur; the preparation method of the alpinia oxyphylla leaf essential oil comprises the following steps that alpinia oxyphylla leaves are taken, dried and smashed, the smashed alpinia oxyphylla leaves are placed in water to be soaked, the material-liquid mass ratio is 1: (15-17), and the soaking time is 0.8-1.2 h; after soaking, distillation is carried out, the distillation time is 4.5-5.5 h, and the distillation temperature is 170-200 DEG C; and after distillation is finished, collecting upper oily liquid to obtain the alpinia oxyphylla leaf essential oil. The prepared alpinia oxyphylla leaf essential oil has broad-spectrum antibacterial and bactericidal effects, and the antibacterial and bactericidal effects are good.

1. Name of the designed product: packing box (Yizhi-fruit of Alpinia oxyphylla). 2. Use of the designed product: a packing box. 3. Design points of the designed product: in shape. 4. Picture or photo showing the design points: perspective view.

The invention discloses a composition and granules for improving memory and a preparation method of the composition and granules, and belongs to the technical field of medicines. The composition capable of improving memory is obtained by mixing poria cocos, rhizoma anemarrhenae, fructus alpiniae oxyphyllae and gastrodia elata according to a specific proportion, and the memory improving granules which are convenient to take and industrialized are prepared through a specific preparation method. The preparation method comprises the following steps: extracting, concentrating and drying the raw materials in the formula, mixing with auxiliary materials, and granulating to finally prepare the granules for improving memory. The granules achieve the effect of improving memory by conditioning viscera and taking both symptoms and root causes into consideration, and meanwhile, the beneficial effects of the granules are also verified by test results in the invention.

The invention discloses a formula and a brewing method of liqueur. The liqueur is prepared from the following raw materials in parts by weight: 100 parts of radix astragali, 100 parts of fructus lycii, 50 parts of mulberries, 50 parts of fructus alpiniae oxyphyllae, 50 parts of rhizoma polygonati, 100 parts of raspberries, 100 parts of American ginseng, 10 parts of saffron crocus, 200 parts of Chinese dates, 100 parts of herba cistanche, 150 parts of honey and 100 parts of cortex cinnamomi. The filtering device has the advantage of being good in drinking effect, and the problems that in the brewing process of existing liqueur, the filtering effect on impurities in the liqueur is poor, the taste of the liqueur can be affected due to the existence of the impurities, the liqueur becomes rough or impure, and therefore the overall drinking experience is affected are solved.

The present invention relates to a sesquiterpenoid compound oxyphylleudne F separated from Alpinia oxyphylla seeds and its application, and a compound with a novel structure is found from Alpinia oxyphylla seeds, and the application of the new compound in the development of kidney protection drugs is realized. The technical solution is to separate and identify a new sesquiterpenoid compound oxyphylleudne F from the n-butanol part of Alpinia oxyphylla seeds, and find through experimental research that the compound can inhibit and attenuate the TGF-β-catenin induced by TGF-β-catenin in a dose-dependent manner. β 1 induces the expression of fibronectin, type I collagen and α The expression of SMA has anti-renal fibrosis activity and can be effectively used to prepare renal protective drugs. The preparation method has good reproducibility and the obtained compound has high purity, which is conducive to further pharmacological and clinical research on it, and has expanded the medicinal value of Alpinia oxyphylla, with huge economic and social benefits.

The present invention belongs to the field of traditional Chinese medicine technology, specifically relating to a traditional Chinese medicine composition for improving cognitive impairment in coronary heart disease and its use. The raw materials of the composition include the following components: Alpinia oxyphylla, Lycium barbarum, Fructus schizonepetae, Lotus seed core, Panax ginseng, Ligusticum chuanxiong, and Paeonia lactiflora. The composition of the present invention can improve cardiac function and structure after acute myocardial ischemia in coronary heart disease, reduce the area of ​​ischemic myocardial infarction, alleviate myocardial cell damage and myocardial fibrosis, alleviate damage to hippocampal neurons and ultrastructural changes, and improve learning and memory functions and cognitive behavioral performance.

The invention relates to the technical field of health food, in particular to a hericium erinaceus and fructus alpiniae oxyphyllae composition for improving memory and cognitive functions of teenagers and old people and maintaining brain health, and particularly relates to a gel candy product taking hericium erinaceus powder, fructus alpiniae oxyphyllae powder, phosphatidylserine and the like as main components and a preparation method of the gel candy product. According to the hericium erinaceus and fructus alpiniae oxyphyllae gel candy, multiple nutrients beneficial to brain health are scientifically proportioned, especially the important components including phosphatidylserine and L-alpha-glucoside phosphocholine are contained, the absorption efficiency of the brain to the key nutrients can be effectively improved, and the problem that the effect is limited due to the single component of common health care products is solved. Besides, the hericium erinaceus and fructus alpiniae oxyphyllae gel candy not only pays attention to providing comprehensive brain support, but also particularly pays attention to specific requirements of users of different age groups, meanwhile, the use safety is ensured by utilizing natural ingredients, and the hericium erinaceus and fructus alpiniae oxyphyllae gel candy aims at overcoming the defects that other products in the current market are single in ingredient, limited in applicable crowd and the like.

The application provides a uniform polysaccharide of Alpinia oxyphylla, a preparation method and application thereof, and belongs to the technical field of medicines. 3 The uniform polysaccharide of Alpinia oxyphylla contains galactose and glucose; the molar ratio of the galactose and the glucose is 3:22; the average molecular weight of the uniform polysaccharide of Alpinia oxyphylla is 5.26*10 3 The application also provides a preparation method of the uniform polysaccharide of Alpinia oxyphylla and application thereof in preparing immunoregulation drugs. The uniform polysaccharide of Alpinia oxyphylla obtained through the specific preparation method has good effects in regulating immunity, and provides a new choice for preparing traditional Chinese medicine innovative drugs for immune system diseases.

This invention discloses a traditional Chinese medicine composition for treating cerebrovascular diseases, belonging to the technical field of cerebrovascular disease drugs. The composition comprises the following components in parts by weight: 10-30 parts of Polygonatum sibiricum, 6-15 parts of Rosa laevigata, 6-12 parts of Euonymus alatus, 6-15 parts of Polygonum cuspidatum, 3-9 parts of Acorus tatarinowii, 3-10 parts of Alpinia oxyphylla, 3-6 parts of Aralia elata septum, 3-10 parts of Rhodiola rosea, 3-10 parts of Bletilla striata, and 1-6 parts of Cinnamomum cassia. This invention addresses the pathological characteristics of cerebrovascular diseases, including long disease courses, multiple risk factors, and involvement of multiple target organs. Through the systematic combination of ten herbs, it can simultaneously achieve cerebrovascular protection, nerve function repair, and protection against multi-organ damage. Animal experiments and clinical observations have confirmed that this composition can significantly improve patients' neurological deficit scores, reduce the incidence of complications, and has clear preventive and therapeutic effects on secondary complications such as stress ulcers and renal impairment, while also possessing antithrombotic and hemostatic properties and high safety.

The invention belongs to the field of research and development of new drugs, and particularly relates to application of a fructus alpiniae oxyphyllae flavone extract (AFOAO) in preparation of drugs for treating diabetes and complications thereof, Parkinson's disease and pulmonary fibrosis diseases. The fructus alpiniae oxyphyllae flavone extract is prepared from 17 components including kaempferol, luteolin, phloretin, catechin and the like. A series of systematic experiments show that a group of specific fructus alpiniae oxyphyllae flavone extracts (mainly comprising 16 active flavones such as kaempferol, apigenin and rutin) can simultaneously improve symptoms such as diabetes and complications thereof, Parkinson's disease and pulmonary fibrosis, and have various pharmacological activities. The invention officially embodies the treatment characteristic of'one medicine with multiple effects' of the traditional Chinese medicine, and has a great application prospect in preparation of medicines for treating diabetes and complications thereof, Parkinson's disease, pulmonary fibrosis and other diseases.

This invention discloses a diphenylheptane compound, a novel chemical component discovered in Alpinia oxyphylla. The invention also identifies the structure of the compound isolated by the above method using physicochemical properties and modern spectroscopic techniques. Furthermore, the invention evaluates the compound's activity using an LPS-induced RAW264.7 cell inflammation model and other activity screening systems, finding that the compound has a certain protective effect on the mouse macrophage line RAW264.7, significantly inhibiting NO release and exhibiting strong anti-inflammatory activity.

The present invention discloses a high-yield nootkatone alcohol dehydrogenase mutant and a preparation method thereof, and is used to synthesize a high-yield nootkatone alcohol dehydrogenase mutant derived from Alpinia oxyphylla ( Alpinia oxyphylla ) alcohol dehydrogenase undergoes site-directed mutagenesis, wherein the mutation is at least one of S197V, M144C, and L196A. The alcohol dehydrogenase mutant provided by the present invention has high catalytic activity. The mutant M144C / L196A / S197V achieves a yield of 99% in the production of nootkatone from nootkadol, 4.32 times that of the original enzyme. The alcohol dehydrogenase mutant catalyzes the synthesis of nootkatone using a simple production process, mild reaction conditions, and an environmentally friendly production process, facilitating the industrial production of nootkatone and possessing broad application prospects.

The application discloses a method for extracting total flavones from Alpiniae Oxyphyllae Fructus based on betaine-ethanol low eutectic solvent ultrasonic assistance, and belongs to the field of plant extraction. The application aims to solve the problems of pollution, high cost, mechanical damage or thermal degradation of flavonoids in the prior art. The method comprises the following steps: adding low eutectic solvent to Alpiniae Oxyphyllae Fructus powder, and then performing ultrasonic extraction; and after the end of the ultrasonic extraction, centrifugation is performed, and the supernatant is obtained, thereby obtaining total flavone extract. The method can realize efficient extraction under mild conditions, effectively avoids thermal degradation and mechanical damage of the flavonoids in Alpiniae Oxyphyllae Fructus, and the solvent component is non-toxic, free of secondary pollution and low in cost.

This invention provides a traditional Chinese medicine composition for treating Yang deficiency constitution and its application. It comprises the following medicinal ingredients in parts by weight: 6-10 parts Eucommia ulmoides leaves, 6-10 parts Cistanche deserticola, 2-4 parts Cinnamomum cassia, 5-7 parts Alpinia galanga, 5-7 parts dried ginger, 5-7 parts Rubus idaeus, 5-7 parts Alpinia oxyphylla, 5-7 parts nutmeg, 3-5 parts walnut kernels, 3-5 parts black sesame seeds, 3-5 parts Lycium barbarum, 3-5 parts longan pulp, 3-5 parts Dioscorea opposita, 3-5 parts jujube, 2-4 parts Euryale ferox, 5-7 parts Astragalus membranaceus, 5-7 parts Codonopsis pilosula, 2-4 parts oyster shell, 5-7 parts Angelica sinensis, and 2-3 parts Saussurea involucrata culture. The preparation method of this traditional Chinese medicine composition is simple, the formulation is reasonable, and the overall effective rate in clinical trials is high.