123 results about "Benzioc acid" patented technology

A long-term fire retarding biochemical liquid composition including: a dispersing agent realized in the form of a major amount of water, for dispersing alkali metal ions dissolved in the water; a major amount of a first fire retarding agent realized in the form of a primary alkali metal salt of a nonpolymeric saturated carboxylic acid, for example, tripotassium citrate, for providing metal potassium ions dispersed in the water when the at least one alkali metal salt is dissolved in the water to form a mixed retardant solution; a minor amount of a second fire retarding agent realized in the form of a secondary alkali metal salt of a nonpolymeric saturated carboxylic acid, for example, potassium, sodium, calcium and / or magnesium benzoate, for providing benzoate ions dispersed in the water when the secondary alkali metal salt is dissolved in the mixed retardant solution, for functioning as a secondary fire retardant agent.

The invention relates to the technical field of polymer dye synthesis, and discloses a monomer for a blue polyester fiber and a preparation method thereof.According to the monomer for the blue polyester fiber, 1, 4-arylamino substituted anthraquinone serves as a color development mother nucleus, a benzoate group is introduced to aryl of the 1, 4-arylamino substituted anthraquinone mother nucleus, and the monomer for the blue polyester fiber is obtained; the benzoate group is connected with the chromophoric parent nucleus through a carbon-carbon bond; the molecular terminal of the monomer for the blue polyester fiber is connected with an exposed ester group through an aryl group, and the exposed ester group is used for transesterification with dihydric alcohol under the melt polycondensation condition of polyester. The novel monomer for the blue polyester fiber, provided by the invention, has excellent color development performance and thermal stability, can be directly used for in-situ synthesis of blue polyester and can be directly used for melt spinning, and the color fastness and coloring uniformity of a product are improved; meanwhile, the monomer for the blue polyester fiber, provided by the invention, is simple in preparation method, low in cost and easy for large-scale production.

The invention provides a chemical or enzymic method regenerated PET and PTA screening method, which comprises the following steps: pretreating a PET or PTA sample 1, and measuring the content of p-toluic acid, the content of p-carboxybenzaldehyde and the content of m-terephthalic acid by using high performance liquid chromatography; the method comprises the following steps: pretreating a PET or PTA sample 2, pretreating by using a high-temperature pyrolysis method, and measuring an isotope ratio of oxygen-18 to oxygen-16 by using an isotope ratio mass spectrometer; the method comprises the following steps: calculating a cleanliness index, an oxy-18 index and a bottle flake index by using a formula based on a test result, and classifying PET and PTA samples through a decision tree according to the indexes; combining and mixing the PET and PTA products based on the classification result and the requirements of downstream customers on the regeneration method and the regenerated material content; the method is convenient, accurate and reliable, the classification result is objective, the screening efficiency of PET and PTA regenerated by a chemical or enzyme method can be improved, and the economic cost is saved.

The invention provides a dyeable high-temperature-resistant modified meta-position aramid fiber and a preparation method thereof. The modified meta-aramid fiber is mainly prepared from a spinning solution prepared from m-phenylenediamine, methyl 3, 5-diaminobenzoate, 3, 3 '-diaminodiphenyl sulfone and an isophthaloyl dichloride copolymer through dry spinning, and the dye uptake of a disperse dye is not lower than 85%; the thermal decomposition temperature is not less than 400 DEG C. The preparation method comprises the following steps. S1, fully continuous polymerization; s2, continuously neutralizing and conveying; s3, direct spinning; and S4, fiber forming and post-treatment. The method has the advantages that (1) the quality difference between batches in the traditional intermittent method is eliminated, and the uniformity and stability of the product performance are realized; and the preparation process is compact, the production efficiency is high and the energy consumption is low. And (2) the dyeing performance of the prepared fiber is obviously improved, the inherent high-temperature-resistant characteristic of the aramid fiber is maintained, and the mechanical property is excellent. And (3) the application range of the meta-position aramid fiber is expanded.

The invention relates to a PET material as well as a preparation method and application thereof. The PET material is prepared from the following components in parts by weight: 75 to 95 parts of PET resin, 2 to 10 parts of PCTG, 3 to 8 parts of flexibilizer, 2 to 5 parts of glass flake and 0.2 to 1 part of poly alkyl glycol dibenzoate. The toughening agent comprises an ethylene-methacrylic acid copolymer and / or ethylene-butyl acrylate. According to the PET material provided by the invention, the PET resin and the PCTG are taken as base materials, the ethylene-methacrylic acid copolymer and / or ethylene-butyl acrylate are / is taken as a toughening unit, the glass flakes are taken as a reinforcing framework, and the poly alkyl glycol dibenzoate is taken as a crystallization inhibitor, so that the PET material has good transparency through the design of all the components; meanwhile, the PET material has good strength and rigidity and can well meet the high-performance requirements of the fields of low-temperature food packaging industry and the like on the PET material.

The invention discloses Leishan fish sauce sour essence as well as a preparation method and application thereof. The leishan fish sauce acid essence is prepared from ethyl acetate, absolute ethyl alcohol, ethyl isovalerate, ethyl hexanoate, isoamyl alcohol, furfuryl alcohol, ethyl lactate, ethyl caprylate, acetic acid, diethyl succinate, methyl salicylate, ethyl benzoate, ethyl laurate, hexanoic acid, phenethyl alcohol, 4-methyl guaiacol, ethyl myristate, ethyl palmitate, ethyl oleate, capsicum oleoresin, ethyl phenylacetate and ginger oil. And lactic acid, glycerol triacetate, ocimene, ethyl isovalerate, ethyl butyrate, anethole and phenylacetaldehyde. The Leishan fish sauce sour essence disclosed by the invention is soft and harmonious in overall fragrance, natural and vivid, still has stable flavor characteristics at high temperature, can make up the problem of flavor deficiency in sour soup products, realizes accurate reproduction and controllable release of composite fragrance, improves the standardization level of products, and effectively improves the preference degree of consumers.

This invention discloses a low-VOCs, low-odor environmentally friendly material for the production of sealing strips for passenger vehicles and its preparation method, belonging to the field of polymer materials technology. The technical solution includes the following raw materials in parts by weight: 100 parts PVC resin; 5 parts stabilizer; 40-60 parts plasticizer; 0.4-0.6 parts lubricant; 1.3-1.5 parts antioxidant; 0.3-0.4 parts ultraviolet absorber; 0.3-0.5 parts deodorizer A; 0.8-1.0 parts deodorizer B; 10-25 parts light active calcium carbonate; 1.0-1.2 parts pigment; deodorizer A is a complex of zinc amino acid, and deodorizer B is benzoic anhydride-intercalated modified aluminum-magnesium hydrotalcite. This invention can capture free, irritating small-molecule alcohols and convert them into esters with milder odors, effectively preventing alcohols from being converted into irritating ethers and ketones during processing, thus reducing the odor and VOCs of passenger vehicle sealing strips.

This invention relates to the field of coating technology, specifically to a low-temperature curing fluorocarbon coating for aluminum alloys and its preparation method. The invention involves adding eugenol, potassium carbonate, and decafluorobiphenyl to obtain modified biphenyl; then adding m-chloroperoxybenzoic acid to prepare a reinforcing agent. Next, γ-epoxypropoxypropyltrimethoxysilane is used to surface modify linear silica fillers, lamellar silica fillers, and dendritic silica fillers to obtain epoxy-modified wear-resistant fillers. Epoxy resin and epoxy-modified wear-resistant fillers are added to xylene, ultrasonically stirred, and then fluorocarbon resin, reinforcing agent, and curing agent are added, followed by continued ultrasonic stirring to obtain the fluorocarbon coating. The fluorocarbon coating prepared by this invention exhibits excellent adhesion, wear resistance, and mechanical strength, thus showing broad application prospects in the field of coating technology.

A rizatriptan microneedle patch, a preparation method therefor, and use thereof. The rizatriptan microneedle patch comprises a substrate and a needle body arranged on a surface of the substrate. The composition of the needle body comprises rizatriptan benzoate and a skeleton material. The skeleton material comprises a combination of dextran and trehalose, copovidone, a combination of polyvinyl alcohol and dextran, a combination of hypromellose and dextran, or a combination of sodium carboxymethyl cellulose and dextran. The rizatriptan microneedle patch has high mechanical strength and cumulative drug permeation.

This invention discloses a method for preparing tert-butyl benzoate peroxide using a microchannel reactor, comprising the following steps: adding liquid alkali to tert-butyl hydroperoxide, allowing it to stand and separate into layers, and obtaining the lower sodium salt; passing the obtained sodium salt into the microchannel reactor, simultaneously passing benzoyl chloride into the microchannel reactor for mixing and reaction; passing the material emanating from the microchannel reactor into an RTB reactor for incubation and reaction to obtain crude tert-butyl benzoate peroxide; purifying the crude tert-butyl benzoate peroxide to obtain tert-butyl benzoate peroxide. This invention employs continuous feeding and achieves the synthesis reaction through a microchannel reactor, reducing the reaction time from several hours to tens of seconds to several minutes, significantly improving reaction efficiency. The entire reaction process in the microchannel reactor used in this invention is a continuous reaction, which is safe and environmentally friendly, has high production efficiency, requires a small equipment footprint, is simple to operate, reduces manual operation, and lowers production costs.

A lubricating oil composition is disclosed. The composition includes a major amount of an oil of lubricating viscosity, one or more alkylhydroxy benzoate compound derived from isomerized normal alpha olefins, and oxidation inhibitor system comprising a molybdenum-containing antioxidant and a diphenylamine. The molybdenum-containing antioxidant is present in an amount to provide at least 120 ppm of Mo to the lubricating oil composition. The diphenylamine is present in an amount to provide 0.5 wt. % or more to the lubricating oil composition.

The present invention relates to antiperspirant and deodorant compositions for correction of body odour, and more particularly relates to antiperspirant and deodorant compositions for human hygiene. The disclosed anti-perspirant and deodorant composition comprises isobutane, propane, butane, cyclopentasiloxane, caprylic / capric triglyceride, stearalkonium hectorite, propylene carbonate, c12-15 alkyl benzoate, parfum, silver lactate, lactic acid, aqua, zea mays starch, menthyl ethylamido oxalate, argania spinosa kernel oil. Furthermore, the active antimicrobial silver ingredient is dermatologically tested and is capable of diminishing odor-causing bacteria in addition to prevention of irritation and itching.

This invention discloses a method for preparing raloxifene EP impurity B, comprising the following steps: dissolving 6-methoxy-2-(4-methoxyphenyl)benzothiophene (Ⅰ) as a raw material in solvent one, adding NIS, and then adding a free radical initiator to react and obtain intermediate III; dissolving 4-[2-(1-pyrrolidinyl)ethoxy]benzoate salt (II) in solvent two, adding solvent two or not, and then adding a chlorinating agent to react and generate intermediate IV; dissolving intermediate III in solvent three, adding a Lewis acid, and then adding intermediate IV, and performing a Friedel-Crafts acylation reaction to generate intermediate V; dissolving intermediate V in solvent four, adding a demethylating agent, and generating bisphenol hydroxyl intermediate VI under demethylation conditions; dissolving intermediate VI in solvent five, adding a reducing agent, and generating intermediate VII through a reduction reaction; dissolving intermediate VII in formic acid, stirring, evaporating, and finally lyophilizing to generate the formate target product VIII.

A bremelanotide pharmaceutical composition, a formulation thereof, a preparation method therefor, and use thereof. The bremelanotide pharmaceutical composition comprises bremelanotide as a pharmaceutically active ingredient, a solvent, and a polymer. The solvent includes one or more of N-methylpyrrolidone, polyethylene glycol, dimethyl sulfoxide, and benzyl benzoate and enables the plasma concentration of bremelanotide to be stably greater than 0.1 ng / mL at 120-168 h, thereby achieving the target sustained release. The bremelanotide pharmaceutical composition can be directly injected and does not require the addition of a thickener, a gel-forming agent, or other excipients.

The present invention relates to combinations of a compound of formula (A-1) with a compound selected from the group consisting of dimpropyridaz, emamectin and isocycloseram, bentioflumin, pioxaniliprole, isoflualanam, cybenzoxasulfyl, vinylfluthrin, cyclobunofen, flupymezotiaz, fentiazoluron, 1-(1,2-dimethylpropyl)-5-methyl-N-prop-2-ynyl-N-(3-pyridyl)pyrazole-4-carboxamide, 1 -[4- [5-ethylsulfonyl-1-methyl-4-[3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]imidazol-2- yl]phenyl]cyclopropanecarbonitrile, [(Z)-[[3-ethylsulfonyl-5-[4-(trifluoromethoxy)phenyl]-2-pyridyl]-[[5- (trifluoromethyl)-2-pyridyl]amino]methylene]amino] acetate, 3-[3-ethylsulfonyl-5-[4- (trifluoromethoxy)phenyl]-2-pyridyl]-4-[5-(trifluoromethyl)-2-pyridyl]-1,2,4-oxadiazol-5-one, 1-(4- chlorophenyl)-2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfanyl)benzene, and emamectin benzoate; and to methods of controlling or preventing damage to plants using such combinations; and to formulations, concentrates and seed treatments comprising such combinations.

The invention discloses an emamectin benzoate nano-pesticide with both leaf adhesion and pH response as well as a preparation method and application of the emamectin benzoate nano-pesticide, and the nano-pesticide is prepared from a composition for the nano-pesticide. Comprising the following components in parts by weight: 2-15 parts of emamectin benzoate, 30-80 parts of a copolymerization surfactant, 4-15 parts of a nonionic surfactant, 10-60 parts of sodium alginate and 2-15 parts of a cross-linking agent. The nano-pesticide disclosed by the invention is slowly released in a neutral environment (pH is 7) and quickly released in a pest midgut alkaline environment (pH is 9-10), the release rate within 12 hours reaches 60% or above, the nano-pesticide can accurately act on target pests, the pesticide effect is improved, and the non-target toxicity is reduced.

The invention discloses a single-component water-based coating composition which comprises acrylic resin and a first compound, and the first compound comprises fatty acid salt and at least one or two of benzoate and nitrite. The invention further discloses a base material coated with the single-component water-based coating composition. The invention further discloses application of the single-component water-based coating composition to form a single coating to provide corrosion resistance and / or water resistance for a substrate.

The invention discloses polybutylene terephthalate resin capable of being spun at a high speed, and the resin is formed by carrying out polycondensation on regenerated terephthalic acid (r-PTA) and 1, 4-butanediol (BDO), the terephthalic acid is regenerated terephthalic acid (r-PTA), and the content of p-toluic acid (p-TA) is less than or equal to 30 ppm; the content of 4-carboxybenzaldehyde (4-CBA) is less than or equal to 10ppm; the intrinsic viscosity (IV) of the resin is from 0.80 to 1.15 dL / g; the terminal carboxyl group content (AV) is less than or equal to 20mol / t; and a molecular weight distribution index (PDI = Mw / Mn) of 1.8 to 2.2. The PBT resin has the characteristics of narrow molecular weight distribution, high melting point and low acid value, and supports 2000-2200m / min high-speed spinning, and the prepared DTY (draw textured yarn) fiber is high in crimp shrinkage rate (good in elasticity) and good in hydrolysis-resistant stability, is widely applied to the field of textile fibers, and is particularly suitable for production of high-end high-elastic fabrics.

The invention discloses an enhanced halogen-free nylon composite material based on polyamide-6 and a preparation method thereof. According to the composite material, synergistic modified polyamide-6 serves as a matrix, maleic anhydride and 3-aminopropyltriethoxysilane are introduced under the melting or reaction condition to conduct synergistic modification on the polyamide-6, 2, 5-dihydroxybenzoic acid is further added to serve as an organic small molecule function regulating agent, and the composite material is prepared. Meanwhile, the halogen-free flame retardant, the reinforcing filler, the compatilizer, the antioxidant and the processing aid are matched to construct a multi-component synergistic effect system. The composite material can obtain excellent halogen-free flame retardant property under the condition of lower flame retardant dosage, has higher mechanical strength, toughness and processing stability, and is suitable for the fields of electronic and electric appliances, automobile parts and engineering structure materials.

The utility model discloses sewage treatment equipment for tert-butyl peroxybenzoate production. The sewage treatment equipment comprises an evaporation tank; the jacket is arranged on the outer side of the evaporation tank, and a steam heating space is formed between the jacket and the evaporation tank; the sealing head is arranged at the top end of the evaporation tank; the stirring driver is arranged on the sealing head; the stirring drive is connected with the stirring shaft, and the stirring shaft is rotatably arranged on the sealing head; the scraping plate is arranged on the stirring shaft. High-temperature steam is discharged into the steam heating space and rapidly heats the evaporation tank, so that the sewage in the evaporation tank is heated and boiled, water in the sewage is converted into steam, and sodium chloride in the sewage is crystallized and separated out. In the treatment process, the stirring shaft is driven by the stirring drive to rotate, sewage is continuously stirred, bumping of the sewage is avoided, high-quality crystal salt can be formed easily, and meanwhile, the inner wall of the evaporation tank is scraped by the scraping plates differently, so that salt is prevented from being hung on the inner wall of the evaporation tank.

To provide a crystal of 2 - (4-acetylbenzyl) - 3 - ((4-fluorophenyl) amino) - 577 - trimethyl-7, 8-dihydro-pyrazolo-imidazo [1, 2-a] 2H [4, 3-e] pyrimidin-4 (5H) - one.SOLUTION: Provided is a crystal of an acid addition salt form selected from, for example, succinate form, citrate form, adipate form, tartrate form (e.g., L-tartrate form), malate form, gluconate form (e.g., D-gluconate form), maleate form, fumarate form, aspartate form (e.g., L-aspartate form), hippurate form, sebacate form, glycolate form, galactarate form, benzoate form, pamoate form, oxalate form and malonate form.SELECTED DRAWING: None

The invention discloses a method for synthesizing loxapine succinate, which comprises the following steps of: carrying out substitution reaction by using 2-nitrofluorobenzene and 2-hydroxy-4-chloromethyl benzoate as raw materials to generate 5-chloro-2-(2-nitrophenoxy) benzoate; nitryl is reduced, and 5-chloro-2-(2-aminophenoxy) benzoate is generated; the method comprises the following steps: carrying out an intramolecular ring closing reaction to generate 2-chlorodibenzo [b, f] [1, 4] oxazepine-11 (10H)-ketone; 2, 11-dichlorodibenzo [b, f] [1, 4] oxazepine is obtained through a reaction and chlorination; the method comprises the following steps: carrying out a C-N coupling reaction of methyl piperazine to generate 2-chloro-11-(4-methylpiperidine-1-yl) dibenzo [b, f] [1, 4] oxazepine; and salifying with succinic acid to generate the loxapine succinate. The method is easily available in raw materials, simple in process and suitable for large-scale production.

The application discloses oily gel microbeads, a preparation method thereof, skin care products and application. The oily gel microbeads comprise polar oil 60-93%, oil phase gel 5-30%, low freezing point oil 2.5-20% and semi-solid oil 0.1-5%, % is the mass percentage of each component in the total mass of the gel microbeads; the polar oil is one or more of glyceryl tri(ethylhexanoate), white pool seed oil, isononyl isononanoate, dicaprylyl carbonate, diethylhexyl carbonate, C12-15 alcohol benzoate, isopropyl myristate, ethylhexyl stearate, ethylhexyl palmitate, castor seed oil, wheat germ oil, sunflower seed oil, wild soybean oil and coconut oil; the freezing point of the low freezing point oil is lower than-65 DEG C. The oily gel microbeads prepared by the application have good low-temperature stability, are spherical in shape, have good uniformity, are easy to spread and absorb, have strong skin adhesion, and have strong moisturizing and repairing functions.

This invention relates to the field of seawater desalination technology, specifically to a high-permeability and selective reverse osmosis membrane and its preparation method. The high-permeability and selective reverse osmosis membrane is obtained by sequentially immersing a porous support layer in an aqueous solution and an oil solution for interfacial polymerization, thereby forming a desalination layer on the surface of the porous support layer. This invention increases the compatibility of the water / oil phases by adding N-methylpyrrolidone to the aqueous phase and methyl benzoate to the oil phase, thereby reducing the surface tension of the two phase solutions, promoting the diffusion of amine monomers into the organic phase, and altering the surface morphology and polymer chain aggregation state of the separation layer. This results in a higher roughness and cross-linking degree of the desalination layer, and improved permeability and selectivity.

The application relates to the field of chemical raw material synthesis, and particularly discloses a preparation method of an ultraviolet absorber UV-1. The preparation method of the ultraviolet absorber UV-1 comprises the following steps: blending p-aminoethyl benzoate, formic acid, N-methylaniline and a catalyst, reacting at a temperature of 0-5 DEG C for 6-7 h, and obtaining the ultraviolet absorber UV-1 after vacuum distillation, wherein the catalyst is FeCl4 / MSNs. The preparation method can improve the utilization rate of raw materials, reduce the corrosion degree of equipment, and make the reaction more easily controllable, has good applicability and operability, brings remarkable optimization effect for the preparation of the ultraviolet absorber UV-1, the uniform corrosion rate of the equipment after running for three months is 0.08 mm / year, the pitting coefficient is as low as 1.1-1.4, the yield of the ultraviolet absorber UV-1 is not lower than 99.1%, and the purity of the ultraviolet absorber UV-1 is not lower than 99.5%.

This invention discloses an ABS surface scratch repair coating and its preparation method, relating to the field of coating technology. The ABS surface scratch repair coating is prepared by reacting 3,9-dichloro-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide with formic acid to obtain intermediate 1; reacting intermediate 1 with diethyl maleate to obtain intermediate 2; reacting intermediate 2 with ethylenediamine to obtain a polyamino phosphorus-containing curing agent; reacting p-hydroxybenzoic acid with 2-chlorocyclopentanone to obtain cyclopentanone benzoate; reacting nano-cerium dioxide sequentially with 3-chloropropyltrimethoxysilane and cyclopentanone benzoate to obtain modified nano-cerium dioxide; and mixing epoxy resin, polyamino phosphorus-containing curing agent, puerarin, and modified nano-cerium dioxide with acetone as a diluent to obtain the ABS surface scratch repair coating. The ABS surface scratch repair coating prepared by this invention has superior weather resistance and flame retardant properties.

The invention belongs to the technical field of battery electrolyte, and particularly relates to nicotinamide-containing aqueous zinc ion battery electrolyte, a battery and a preparation method. The aqueous zinc ion battery electrolyte provided by the invention comprises the following components: a solvent, zinc salt, nicotinamide and 3-(1, 2, 4-triazole-1-yl) methyl benzoate. Nicotinamide is enriched on an anode / electrolyte interface through chemical adsorption, so that by-product deposition is blocked, dendritic crystals are inhibited, zinc nucleation overpotential is remarkably reduced, uniform nucleation sites are increased, three-dimensional diffusion growth is induced, (002) crystal face dominated compact zinc deposition is realized, and polarization voltage is remarkably reduced. And the 3-(1, 2, 4-triazole-1-yl) methyl benzoate preferentially reacts with water to passivate the reaction activity of the water and further inhibit the side reaction in the aqueous electrolyte. By virtue of the synergistic mechanism, the electrolyte endows the aqueous zinc ion battery with high specific capacity and excellent cycling stability.

The invention relates to the technical field of synthesis of biodegradable polyester high polymer materials, in particular to a preparation method of a tetraphenylethylene rigid structure modified PBAT copolyester material, tetraphenylethylene and PBAT are combined, so that the material has a certain fluorescence property, meanwhile, the crystallinity and mechanical property of the material can be improved, and the material has a good application prospect. The application range of the material is expanded; in order to avoid low reaction activity of 4, 4 '-(2, 2-diphenylethyl-1, 1-diyl) dibenzoic acid and alcohol caused by complex structures of 4, 4'-(2, 2-diphenylethyl-1, 1-diyl) dibenzoic acid and 1, 4-butanediol, the esterification reaction is firstly subjected to branched esterification and then is mixed, so that the yield is increased.

The invention relates to the technical field of pesticide synthesis, in particular to a method for synthesizing a saflufenacil intermediate, which comprises the following steps: taking ethyl trifluoroacetoacetate and 2-chloro-4-fluoro-5-aminobenzoate as raw materials, reacting under the action of alkali, and continuously evaporating out low-boiling-point alcohol in the reaction process to obtain an intermediate 1; then adding methylamine hydrochloride turbid liquid into the system, and performing azeotropic dehydration in the reaction process to obtain an intermediate 2; and finally, introducing a phosgene reagent into the system, and carrying out ring closing on the obtained intermediate 2 to obtain a target product. According to the method, cheap and easily available raw materials are used, a uracil ring is directly constructed through a one-pot three-step reaction, and the saflufenacil intermediate is synthesized, so that the process operation is greatly simplified; the target product synthesized by the method has higher yield and purity, the cost is reduced, the solvent can be recycled, the emission of three wastes is reduced, and the subsequent industrial production of saflufenacil is facilitated.

This invention provides a method for preparing and applying a controlled-release agent of emamectin benzoate, belonging to the field of nanopesticide technology. This invention uses PFC-1, a hydrogen-bonded organic framework material with a porous structure, as a drug carrier. After loading emamectin benzoate through its porous structure, the loaded system is further modified by surface encapsulation with sodium lignosulfonate. The resulting nano-formulation with controlled-release function is called emamectin benzoate nano-controlled-release agent. The prepared drug-loaded system exhibits good insecticidal activity against diamondback moth. The preparation method includes a method for preparing emamectin benzoate-loaded agents. The prepared system has a high loading capacity of 19.6%. The drug-loaded system provided by this invention has good insecticidal effect against diamondback moth and exhibits pH-selective release effect in the midgut environment of the diamondback moth.