10 results about "Benzyl benzoat" patented technology

A bremelanotide pharmaceutical composition, a formulation thereof, a preparation method therefor, and use thereof. The bremelanotide pharmaceutical composition comprises bremelanotide as a pharmaceutically active ingredient, a solvent, and a polymer. The solvent includes one or more of N-methylpyrrolidone, polyethylene glycol, dimethyl sulfoxide, and benzyl benzoate and enables the plasma concentration of bremelanotide to be stably greater than 0.1 ng / mL at 120-168 h, thereby achieving the target sustained release. The bremelanotide pharmaceutical composition can be directly injected and does not require the addition of a thickener, a gel-forming agent, or other excipients.

The present invention provides a repellent composition for mites which is excellent in mite-repelling effect against indoor mites even after a long period of time and is also excellent in safety to humans and animals. The present invention relates to a repellent composition for mites, which contains: (a) 1,8-cineol and / or 1,4-cineol and (b) a perfume ingredient, wherein the perfume ingredient contains one or two or more kinds of perfume compounds having a logP value of 2.0 to 5.5. The mixing ratio (a) / (b) of the (a) ingredient to the perfume compounds contained in the (b) ingredient is set to 5 to 100 on a mass basis. The perfume compounds contained in the (b) ingredient are at least one selected from the group consisting of ethyl cinnamate, allyl caproate, 3-methyl-5-phenyl-1-pentanol, citronellol, δ-dodecalactone, β-ionone, benzyl benzoate, linalyl acetate, geranyl acetate, tricyclo decenyl propionate, benzyl salicylate, limonene, and amyl salicylate.

The invention belongs to the technical field of plant genetic engineering, and discloses a coding gene of benzyl benzoate 2-hydroxylase participating in a rice PAL-dependent salicylic acid synthesis pathway and application of the coding gene, and the nucleotide sequence of OSD3 is SEQ ID NO: 1; the nucleotide sequence of a coding protein region is SEQ ID NO: 2; the amino acid sequence of the coded protein is SEQ ID NO: 3; according to the invention, an OSD3 gene is knocked out through CRISPR / Cas9 under the background of Zhonghua 11, a mutant osd3 of which the SA of a rice leaf is reduced to 20% of that of a wild type is obtained, and an OSD3 overexpression plant is created by constructing an OSD3-pMDC43 overexpression vector.

This invention belongs to the field of polyether polyol synthesis technology, specifically relating to bio-based high-strength polyether ester polyols and their preparation methods. The bio-based high-strength polyether ester polyol is obtained from the following raw materials: small molecule polyol, catalyst, bio-based epoxide, and bio-based phenyl ester compound; the bio-based epoxide is one or more of limonene epoxide, α-pinene oxide, and caryophyllene oxide; the bio-based phenyl ester compound is one or two of benzyl benzoate and benzyl cinnamate. The raw materials used in this invention can be obtained through natural plant extraction, achieving full bio-based polyether ester polyol production, thus fundamentally reducing dependence on fossil resources. By introducing a large number of cyclic and benzene ring structures into the polyol molecule, the resulting product is applied in the field of rigid polyurethane foam, increasing the content of rigid groups in the molecular chain structure, and significantly improving the strength of rigid polyurethane foam compared to traditional polyether polyols.

This invention discloses the application of benzyl benzoate in the preparation of repellents for red imported fire ants. Experiments verified that after treatment with benzyl benzoate at a concentration of 1 μL / mL or higher for 0.5 h, the feeding and repellency rate of red imported fire ant workers reached 92.74%. After 12 h of treatment, benzyl benzoate at a concentration of 10 μL / mL or higher still maintained a good repellent effect, indicating that benzyl benzoate has a long-lasting repellent activity against red imported fire ants. After treatment with benzyl benzoate at a concentration of 50 μL / mL or higher for 24 h, the burrowing behavior of red imported fire ant workers was significantly reduced. Benzyl benzoate at a concentration of 10 μL / mL or higher showed good repellent effects against red imported fire ants and can be used in future red imported fire ant protective agents; benzyl benzoate at a concentration of 50 μL / mL or higher can be used in red imported fire ant soil repellents.

This invention relates to the field of progesterone preparation technology, specifically to a progesterone lipid liquid crystal suitable for injection, its preparation method, and the pharmaceutical uses of the product. The progesterone lipid liquid crystal injection provided by this invention is a lipid liquid crystal system formed by mixing an oil phase and an aqueous phase. The oil phase includes progesterone, benzyl benzoate, phospholipids, vitamin E, and oleic acid, while the aqueous phase includes water for injection. This invention optimizes the mass ratio of phospholipids to oleic acid in the oil phase to 10:1, and the mass ratio of progesterone, benzyl benzoate, and vitamin E to 2:6:(5-3), resulting in a stable lipid liquid crystal system that improves injection compliance, reduces fat deposition, and achieves sustained drug efficacy for more than 12 hours.

Provided is a superior, novel heterocyclic compound with improved solubility in oil such as sesame oil and benzyl benzoate, which has a broader treatment spectrum, causes less side effects, and is superior in tolerability and safety, and use thereof. A heterocyclic compound represented by the formula (I) wherein each symbol is as defined in the specification, or a salt thereof.

The invention discloses a preparation method of an antibacterial anti-mite blanket, and belongs to the technical field of blanket preparation. The preparation method of the antibacterial and anti-mite blanket is used for solving the technical problem that in the prior art, the antibacterial and anti-mite performance of the blanket needs to be further improved, and comprises the following steps that non-woven fabric is soaked in antibacterial finishing liquid according to the soaking ratio of 1: (30-32), and pretreatment base cloth is obtained after aftertreatment. Benzyl benzoate is used as an anti-mite active component, anti-mite capsules are prepared through crosslinking of sodium alginate, polyvinyl alcohol and delta-glucolactone, the anti-mite capsules are doped into a polyacrylonitrile and dimethylformamide system, modified fibers are prepared through electrostatic spinning, then chitosan and polyhexamethylene biguanide hydrochloride are used as main materials to construct an anti-bacterial finishing liquid, and the anti-mite finishing liquid is prepared through electrostatic spinning. And finally, the antibacterial and anti-mite blanket is obtained through polyurethane hot-pressing compounding, so that not only is the antibacterial and anti-mite performance of the blanket improved, but also the mechanical property of the blanket is improved.

This invention discloses a plum blossom fragrance and its artificial preparation method, belonging to the field of fragrance and flavor technology. The plum blossom fragrance is composed of the following components by mass percentage: cinnamyl alcohol 60.8%-74.4%, eugenol 4.5%-5.6%, benzyl acetate 0.2%-0.3%, 3-phenylpropanol 1.3%-1.7%, cinnamyl acetate 1.1%-1.3%, benzaldehyde 1.1%-1.3%, 4-vinylphenol 17.7%-21.6%, benzyl benzoate 3%-3.7%, nonanal 0.06%-0.1%, and hexanal 0.02%-0.05%. The obtained plum blossom fragrance has a similarity of up to 7.25 / 10 to the aroma of natural plum blossoms, and has advantages such as high aroma reproduction and controllable cost.

The invention discloses application of ketoisophorone and benzyl benzoate in preparation of a medicine for treating diabetes, and belongs to the technical field of biological medicine. In-vivo and in-vitro studies find that after a T2DM animal model and a GlcN cell model are treated through KSP independent administration, BZT independent administration and KSP and BZT 1: 3 combined administration, compared with a model group, the blood glucose regulation effect of a combined administration group is most remarkable: the area under an fasting blood glucose and oral glucose tolerance test (OGTT) curve is in dose-dependent reduction, and the area under the curve is in dose-dependent reduction; an insulin tolerance test (ITT) result shows that the insulin sensitivity is obviously improved; in animal experiments, glycogen generation in liver tissues is increased, and balloon-like deformation and fatty degeneration accumulation conditions are relieved.