The invention relates to a poison bait for exterminating red fire ants, belonging to the field of chemical insecticide, which comprises the components with the following weight percent: insecticide technical product 0.5-1.0%, attractant 40-48%, bait carrier 50-60%, preservative 0.5-1.0%, and the insecticide technical product adopts two components of A and B as assistant components, and attrahent adopts three components of animal albumin powder, edible vegetable oil and flavoring agent as assistant components. The inventive bait formulation mixing insecticide technical product and attrahent is strong in attractive effects, good in palatability, stable in field performance, large in moving load, the medicament in the ant group is evenly transmitted to each grade of the red fire ants, ergates can be killed directly, causing grubs to develop irregularly of die, causing queen ants to be sterile or killing the queen ants. The poison bait is friendly on environment, high in security, which is suitable for comprehensive control on the red fire ants in the field, fruit forest, home, school and the like.