Absorbable suture anchor and preparation method thereof

A technology of absorbing bands and anchors, applied in the direction of nails, U-shaped nails, mechanical equipment, etc., can solve the problems of small shear, inflammatory reaction, anchors cannot be fused, etc., and achieve the effect of high reliability

Inactive Publication Date: 2020-12-01
花沐医疗科技(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although titanium alloy and PEEK have good biocompatibility, these two materials cannot be absorbed, and the fusion between the anchor and the bone cannot be performed
Absorbable anchors are a trend in the development of wire anchor technology due to their small shear to ligaments, absorbability, and perfect biological fusion of bone and soft tissue. Sutures, which stay in the body for a long time, can also lead to an inflammatory response

Method used

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  • Absorbable suture anchor and preparation method thereof
  • Absorbable suture anchor and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0028] see figure 1 and 2 , the present embodiment provides a kind of absorbable threaded anchor, wherein the absorbable anchor adopts L-polylactic acid (PLLA), the molecular weight is 400,000, the weight percentage is 60%, and the hydroxyapatite (HA) (20 μ m) The weight percentage is 40%, and the absorbable anchor has a molecular weight of 200,000 after being sterilized by ethylene oxide. The absorbable suture is made of polylactic acid-glycolic acid (PLGA), with a molecular weight of 500,000 and a single filament diameter of 0.4mm. The absorbable suture has a molecular weight of 200,000 after being sterilized by ethylene oxide.

[0029] Its preparation method is as follows:

[0030] (1) Drying L-polylactic acid and hydroxyapatite respectively, then mechanically stirring and mixing;

[0031] (2) Melt blending the homogeneously mixed materials:

[0032] a. First, set the temperature of the melting zone (upper, middle, and lower) of the blender to 200°C, and the screw speed...

Embodiment 2

[0041] This embodiment provides a kind of absorbable anchor with wire, wherein the absorbable anchor adopts L-polylactic acid (PLLA), the molecular weight is 400,000, the weight percentage is 70%, and the weight of hydroxyapatite (HA) (5 μm) The percentage is 30%, and the absorbable anchor has a molecular weight of 200,000 after being sterilized by ethylene oxide. The absorbable suture is made of polycaprolactone (PCL), with a molecular weight of 300,000 and a single filament diameter of 0.4mm. The absorbable suture has a molecular weight of 200,000 after being sterilized by ethylene oxide.

[0042] Its preparation method is with embodiment 1.

Embodiment 3

[0044] This embodiment provides a kind of absorbable anchor with wire, wherein the absorbable anchor adopts L-polylactic acid (PLLA), the molecular weight is 400,000, the weight percentage is 80%, and the weight percentage of β-tricalcium phosphate (20 μm) is 20%, the absorbable anchor has a molecular weight of 200,000 after being sterilized by ethylene oxide. The absorbable suture is made of polydioxanone (PPDO), with a molecular weight of 300,000 and a single filament diameter of 0.4mm. The absorbable suture has a molecular weight of 200,000 after being sterilized by ethylene oxide.

[0045] Its preparation method is with embodiment 1.

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Abstract

The invention belongs to the technical field of medical equipment, and particularly relates to an absorbable suture anchor and a preparation method thereof. The suture anchor comprises an anchor bodyand a suture. The material of the anchor is formed by compounding polylactic acid and inorganic calcium phosphate, wherein the polylactic acid is L-polylactic acid (PLLA) or L-racemic polylactic acid(PLDLLA) or a combination of the L-polylactic acid (PLLA) and the L-racemic polylactic acid (PLDLLA), and the inorganic calcium phosphate is hydroxyapatite (HA) or beta-tricalcium phosphate (TCP) ora combination of the HA and the TCP. The suture is formed by weaving absorbable monofilament materials, and the absorbable monofilament materials comprise one or more of polylactic acid-glycolic acid(PLGA), polycaprolactone (PCL), polydioxanone (PPDO), polyhydroxyalkanoate (PHA) and polyhydroxybutyric acid (PHB). The anchor disclosed by the invention is formed by compounding the polylactic acid and the calcium phosphate, and meanwhile, the absorbable suture is adopted, so that degradation and absorption are carried out while bones and soft tissues grow together, and perfect biological fusionis achieved.

Description

technical field [0001] The invention belongs to the technical field of medical equipment, and in particular relates to an absorbable threaded anchor and a preparation method thereof. Background technique [0002] Anchor with wire is an implantable medical device that connects damaged soft tissue to bone. It is currently widely used in many fields such as rotator cuff repair in sports medicine, elbow joint, knee joint, and wrist joint repair. Anchor with wire is composed of two components: suture and anchor. In the past 5 years, the materials of anchor with wire used clinically mainly include titanium alloy, polyetheretherketone (PEEK) and so on. [0003] Although titanium alloy and PEEK have good biocompatibility, these two materials cannot be absorbed, and fusion between the anchor and bone cannot be performed. Absorbable anchors are the development trend of anchors with wires because of their small shear to ligaments, absorbability, and perfect biological fusion of bone a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06A61L31/02A61L31/14A61L17/12A61L17/10A61B17/064
CPCA61B17/0642A61B2017/00004A61B2017/0649A61L17/105A61L17/12A61L31/028A61L31/06A61L31/148C08L67/04
Inventor 胡艳飞王云兵董超杰罗宇星
Owner 花沐医疗科技(上海)有限公司
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