167results about How to "No toxic reaction" patented technology

The invention provides a nano artificial dura mater with a plurality of functional layers, which comprises a structure with at least two layers; the layer facing the brain is a hydrophobic anti-adhesion electrospun layer; and the layer back to the brain is a hydrophilic nano cytoskeletal layer. The invention also provides a method for preparing the nano artificial dura mater, which comprises the following steps: preparing an electrospun solution of a hydrophobic polymer; preparing an electrospun solution of a hydrophilic polymer; preparing the prepared electrospun solution of the hydrophobic polymer into the hydrophobic anti-adhesion electrospun layer through static spinning; and preparing the hydrophilic nano cytoskeletal layer on the anti-adhesion electrospun layer from the prepared electrospun solution of the hydrophilic polymer through static spinning, receiving a membrane structure, and obtaining the nano artificial dura mater. The mechanical features of the nano artificial dura mater can meet the requirements on tensile strength and flexibility of adaptation diseases; and the nano artificial dura mater can be freely cut as required, and has wide application prospect.

The invention discloses essence containing chitosan oligosaccharide and jellyfish collagen and a facial mask manufactured from the essence. The essence is prepared by mixing the following components: chitosan oligosaccharide, jellyfish collagen, lecithin, hydroxyl prolinol ester silanol, hydroxyethyl ethylcellulose, xanthan gum, a portulaca oleracea extract, glycerol, butanediol, phenoxyethanol, ethylhexylglycerin and water. The facial mask can be manufactured by soaking a carrier facial mask, that is, a biological cellulose facial mask containing chitin, into the essence till being completed wetted. The essence of the facial mask contains chitosan oligosaccharide and jellyfish collagen, and has a good synergistic effect with the carrier facial mask (the biological cellulose facial mask containing chitin). Compared with an ordinary cellulose facial mask (such as cellulose obtained from wood pulp and cellulose obtained from coconuts), the biological cellulose facial mask containing chitin is relatively low in density, relatively large in pore surface, high in aperture, relatively strong in absorption property and capable of conducting more active matters.

A broad-spectrum antibacterial nano ointment is prepared from inorganic antibacterial silver nanoparticles, matrix, borneol, mint oil and menthol. Its advantages are high effect and safety, and no poison and irritation. It is suitable for skin wound, acne, beriberi, etc.

The invention discloses a nano-silver antibacterial moisture-preserving skin refreshing toner. The skin refreshing toner is characterized in that the skin refreshing toner comprises following components by weight: 0.2-10% of a moisture-preserving agent, 0.1-3% of a nutritional agent, 0.0005-0.1% of nano-silver and 0.001-0.1% of an essence, the balance being water. The skin refreshing toner is free from organic preservatives and uses the nano-silver as an anticorrosion antibacterial agent. The nano-silver not only has an anticorrosion function to the product, but also has a function of antisepsis and anti-inflammation and a function of accelerating restoration of damaged skin. In addition, the skin refreshing toner is colorless and transparent, strongly stable, mild, fresh, and nonirritating. The skin refreshing toner has a perfect moisture preserving function, can replenishing skin with water rapidly, and also has functions of weakening skin winkles, enhancing skin elasticity, removing skin toxin, and activating skin. A preparation method has characteristics of simple operation, wide parameter adjustable range, low energy consumption, short period, and the like, and is particularly suitable for pilot plant test amplification and industrialized large-scale production.

A health-care sobering-up food is prepared from pueraria root and flower, pomelo peel, green tea, haw, ginseng, isatis root, liquorice root, tangerine peel and ganoderma through pulverizing, proportional mixing, immersing, steaming, filtering and loading in containers.

The invention provides a magnetic nano silver antibacterial material for sterilization treatment in medical treatment and / or drinking water and a preparation method thereof. An antibacterial agent provided by the invention takes magnetic nanoparticles coated with silica gel as a core and inlaid with antibacterial particles on the outer layer, is preferably a Fe3O4 magnetic nano antibacterial material which is inlaid with silver nanoparticles and coated with silica gel. The antibacterial agent simultaneously has large special surface area of nano material, magnetic separation capacity and magnetic target of magnetic material, dispersant effect of a silica gel coating layer, protection action on the core and strong antibacterial ability of nano silver. In addition, the antibacterial agent issimple to prepare and convenient to operate and can realize directional sterilization, thereby having wide application prospect in medical care and food sanitation sterilization treatment.

The invention relates to a traditional Chinese medicine composition for invigorating the kidney, strengthening yang, replenishing essence, and reinforcing vitality, and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following thirty five traditional Chinese medicines: cynomorium songaricum, rhizoma curculiginis, morinda root, Angelica sinensis, fructus cnidii, broomrape, Chinese chive seed, Chinese magnoliavine fruit, red ginseng, bull penis, dog kidney, antler, black sliced aconite, cinnamon, common fennel, actinolite, pepper, dodder, eucommia, flasem milkvetch seed, Codonopsis pilosula, cornel, herba epimedii, Astragalus root, Chinese yam, prepared rehmannia root,fructus psoraleae, wolfberry fruit, raspberry, polygala, lotus stamen, cherokee rose, rhizoma alismatis,licorice and tuckahoe. The traditional Chinese medicine composition has the efficacies of invigorating the kidney, strengthening yang, replenishing essence, and reinforcing vitality, is mainly used for the diseases of insufficiency of impotence, spermatorrhea, prospermia and the like caused by the kidney-yang or deficiency of the kidney-yin, has remarkable clinical pharmacodynamic testing effect, is high in bioavailability, and has not any toxic or side effect.

The invention discloses a method for quickly preparing polyethylene glycol regulated and controlled nano hydroxyapatite and belongs to the field of preparation of biomedical materials. The method comprises the following process steps: preparing a calcium salt solution and a phosphate solution respectively, and mixing the calcium salt solution and the phosphate solution with equal volumes; adjusting the pH value of a reaction system by using ammonia water while stirring; adding polyethylene glycol, and heating the reaction system; and performing centrifuging and washing after reaction, and collecting granular deposits to obtain nano hydroxyapatite granular powder. The method disclosed by the invention is simple in preparation process, strong in laboratory operability, low in production cost and high in product yield and is suitable for laboratory research application and industrial production; and moreover, the prepared rod-shaped nano hydroxyapatite has good dispersity, does not have toxic reaction to normal cells and cancer cells, and has a huge application potential in the fields of biomedicine and biological materials such as drug controlled-release vectors, gene therapy vectors and the like.

The invention discloses a traditional Chinese medicine compound formulation for treating dysmenorrhea. The traditional Chinese medicine compound formulation is prepared from the following crude drugs in parts by weight: 1-15 parts of flos carthami, 1-15 parts of olibanum, 1-15 parts of myrrh, 1-15 parts of rhizoma wenyujin concisum, 1-15 parts of cassia twig, 1-15 parts of lignum dalbergiae odoriferae, 1-9 parts of resina draconis, 1-15 parts of lindera aggregate, 1-18 parts of rhizoma corydalis, 1-9 parts of folium artemisiae argyi, 1-9 parts of as arum and 0.5-9 parts of borneol. By adopting the traditional Chinese medicine formulation, the twister reaction times of dysmenorrhea model rats can be obviously reduced, uterine contractions rhythm disorders can be coordinated by adjusting the balance of prostaglandin level inside a sufferer body by inference, meanwhile, the neuropeptide P substance level is reduced by interaction between the systems in an immune neural network, and proinflammatory cytokines such as 1L-1beta are reduced, so as to achieve the target of treating dysmenorrhea. The invention also discloses a preparation method and use of the traditional Chinese medicine compound formulation.

The invention discloses an active polysaccharide composite bone repair material which is good in biocompatibility, good in plasticity, certain in mechanical strength and moderate in degradation velocity in bodies and can meet clinical requirements. The active polysaccharide composite bone repair material comprises a bottle A and a bottle B, wherein the bottle A comprises powder of tetracalcium phosphate, calcium hydrophosphate, chitosan, monosodium phosphate and hydroxypropyl methylcellulose; the bottle B comprises mannitol, an MES solution and a rhBMP-2 biological active factor freeze-dried aquatic product. The active polysaccharide composite bone repair material can induce formation of new bone in a human body, can form active tissue, has the advantages of good compatibility, plasticity and the like, is free of toxic reaction and can be tightly connected with sclerotin after being cured.

The invention relates to a nasographic capsule. The traditional Chinese medicinal materials for preparing the nasographic capsule are: 300 to 450 grams of fried fructus xanthil, 100 to 150 grams of lily magnolia, 200 to 300 grams of angelicas dahurica, 100 to 150 grams of centipede, 300 to 450 grams of peppermint, 300 to 450 grams of radix scutellariae and 100 to 150 grams of liquorice. The auxiliary material for preparing the nasographic capsule comprises at least one of the followings: 3 to 10 percent of methylcellulose, 5 to 15 percent of ethylcellulose, 3 to 6 percent of sodium carboxymethyl cellulose, adequate hydroxypropyl methylcellulose, 3 to 20 percent of microcrystalline cellulose, 5 to 20 percent of dextrin, 3 to 15 percent of calcium hydrophosphate, 5 to 20 percent of starch, 0.25 to 2.0 percent of magnesium stearate, 0.5 to 2.0 percent of stearin, 1 to 3 percent of calcium phosphate, 3 to 6 percent of talcum powder, 1 to 3 percent of colloidal silica and adequate ethanol, wherein, the percentage of the auxiliary material is the weight percentage of the made medicine. The invention makes the prior oral pill into the capsule after technical study, thereby the nasographic capsule not only gives play to the function of the prior prescription medicinal odour but also improves the bioavailability; and the nasographic capsule has the characteristics that: the nasographic capsule is convenient in taking, reduces the peculiar smell for directly taking the pill, and is suitable for wide medicated crowd, etc.

The invention provides a preparation method and applications of pig spleen transferfactor. According to the preparation method, frozen-breaking, freeze thawing breaking, and centrifugal process are combined for transferfactor production, yield is guaranteed, and at the same time production temperature is reduced, and the activity of the transferfactor can be guaranteed preferably. And in addition, the prepared transferfactor contains no protein, is a small molecular peptide, possesses no pyrogen, is a widely used immunomodulator, is capable of increasing vaccine titer, and can be used for improving animal immunity and improving production performance; the activity is not influenced by pancreatic enzymes; and no toxic reaction is caused. When the pig spleen transferfactor is combined with vaccine, animal immunity can be improved, vaccine titer is increased at the same time, body immune response period is shortened, and antibody lasting time is prolonged.

The invention discloses a small and medium diameter artificial blood vessel with adjustable pressure and flow. The artificial blood vessel comprises a blood vessel wall, a blood vessel cavity is in the blood vessel wall, and a pressure and flow controller capable of adjusting the diameter of the artificial blood vessel is arranged outside the artificial blood vessel. Concave and convex grains are arranged on the blood vessel wall. The pressure and flow controller comprises a fixed shell and a control spring, wherein the fixed shell takes the shape of a cylindrical structure, and the control spring is configured to be a cylindrical structure, the control spring is arranged in the fixed shell and sleeved outside of the blood vessel wall of the artificial blood vessel, the control spring is provided with a limit spring handle for adjusting the diameter of the blood vessel, and the spring handle passes through a control frame. The fixed shell is provided with position fixing holes, and the control spring is provided with position fixing holes. The fixed shell is provided with a fastener. The pressure and flow controller comprises a mechanical pressure and flow controller, an in-vitro remote control pressure and flow controller and an in-vivo induction pressure and flow controller. The blood vessel is applicable to controlling the size of fractional flow according to an induced pressure of a hepatic portal vein after a portosystemic blood vessel is anastomosed and shunted so as to ensure the hepatic portal vein perfusion pressure required by individuals.

The invention relates to a veterinary medicine, in particular to a Chinese traditional medicine composition for treating proventriculitis of chicken.The Chinese traditional medicine composition consists of codonopsis pilosula, cortex cinnamomi, radix astragali, white atractylodes rhizomes, endothelium corneum gigeriae galli, betel nuts, montmorillonite, cuttlebone, cortex moutan and licorice roots.Related experiments show that the Chinese traditional medicine composition has the functions of warming yang, dispelling cold, invigorating spleen, supplementing qi, benefiting the liver, invigorating the stomach and removing the necrotic tissues and promoting granulation, can warm yang, dispel cold, replenish qi to invigorate the spleen, cure indigestion, stimulate appetite and strengthen a digestive function, can also reduce swelling, resolve mass, activate blood, remove stasis, remove the necrotic tissues, promote granulation and repair injured glandular stomach tissues.In addition, the Chinese traditional medicine composition is free of toxic and side effects and is suitable for treatment of the proventriculitis of the chicken.

The invention relates to a Chinese medicine preparation for preventing miscarriage and a preparation method thereof. The preparation is prepared from 14 traditional Chinese medical herbs including 20 to 30 portions of prepared rhizome of rehmannia, 20 to 30 portions of oyster shell (calcined), 15 to 15 portions of Schisandra chinensis, 5 to 15 portions of colla corii asini, 15 to 25 portions of mistletoe, 10 to 20 portions of Morinda officinalis (without core), 15 to 25 portions of bighead atractylodes rhizome (roasted), 15 to 25 portions of grains of paradise, 20 to 30 portions white paeony root, 20 to 30 fossil fragments (calcined), 15 to 25 portions of teasel root, 15 to 25 portions of medlar, 15 to 25 portions of bark of eucommia (carbonized) and 15 to 25 portions of dodder seed( cake). The preparation has functions of tonifying kidney, nourishing thoroughfare and conception vessels and preventing miscarriage, and, compared with the prior art, has characteristics of more reasonable formula, steady curative effect and remarkably improved potency and high cure rate. The preparation has extremely good curative effect on threatened abortion, habitual abortion and infertility caused by abortion.

The Chinese medicine preparation Maidangrutong for curing agalactosia due to postpartum weakness with the functions of raising milk-secretion quantity and promoting lactation is made up by using the Chinese medicinal materials of astragalus root, Chinese angelica root, ophiopogon root, trichosanthes root, globethistle, vaccaria seed and stachyurus pith, and can be made into granules, tablet, capsule and oral liquor, and can obtain obvious therapeutic effect.

The invention discloses a composition for removing halitosis. The composition is prepared from the components in parts by weight: 40-50 parts of green tea, 30-40 parts of mint, 30-40 parts of tangerine peel, 30-40 parts of jasmine, 20-30 parts of honeysuckle, 20-30 parts of chrysanthemum, 10-20 parts of mulberry leaves, 10-20 parts of eupatorium fortunei and 10-20 parts of loosestrife. With the adoption of the composition, by utilizing the comprehensive action of various traditional Chinese medicines, the halitosis is treated, the effect is obvious, and the components do not have a chemical sweetener without toxicity and harm to a human body; and as all selected components are common Chinese herbal medicines, the composition is wide in sources and low in the cost.

The invention discloses a traditional Chinese medicine composition for treating climacteric syndrome, and a preparation method and a quality detection method thereof. The traditional Chinese medicine composition is composed of the following components in parts by weight: 25-45 parts of glossy privet fruit, 10-20 parts of sealwort, 10-20 parts of dogwood, 10-20 parts of wolfberry fruit, 10-20 parts of eclipta, 13-23 parts of radix polygonum multiflorum preparata, 5-15 parts of coptis chinensis, 10-22 parts of rhizoma anemarrhenae, 10-22 parts of dragon bone, 5-14 parts of oyster, 8-18 parts of buckeye, 5-15 parts of fingered citron, 5-15 parts of radix scrophulariae, 6-18 parts of citron and 5-14 parts of cortex albiziae. The preparation method of the traditional Chinese medicine composition is scientific and reasonable. The quality standards include a method for identifying the wolfberry fruit, the coptis chinensis and the rhizoma anemarrhenae and a method for measuring the content of oleanolic acid. Pharmacodynamic tests achieve excellent test results and toxicity tests indicate that the clinical given dosage is safe; therefore, the traditional Chinese medicine composition is a safe and effective drug for treating the climacteric syndrome; the traditional Chinese medicine composition has the advantages of accurate therapeutic principle, novel formula, strong efficacy targeting performance, accurate clinical effects and no obvious toxic or side effects.

The invention discloses a non-toxic inner wall decorative material, which comprises a base layer and a decorative layer coated on the base layer. The decorative layer comprises the following components in parts by weight: 0-100 parts of emulsion polyvinyl chloride (K=52-67), 100-0 part of emulsion polyvinyl chloride (K=70-80), 30-120 parts of plasticizer, 1-10 parts of stabilizer, 50-300 parts of smoke suppressor and 0.1-5 parts of antifungal and antibacterial agents. The invention is characterized in that the plasticizer comprises a main plasticizer and an auxiliary plasticizer, the main plasticizer is non-phthalate plasticizer, and concretely is any one of phosphate, phosphite ester, esters of fatty acids, polyester, epoxy-ester and chlorinated compounds; and the auxiliary plasticizer is chlorinated paraffin. As the formulation has no toxic component, no toxic reaction is generated when the wall material is contacted with people; flue gas is non-toxic when a fire happens, thus avoiding poisoning of the fire-afflicted people; the wall material is neither combustible nor combustion-supporting, the generated flue gas is less, thus greatly reducing the probability of coma and asphyxia of the fire-afflicted people.

The compound antilipemic Chinese medicine prepared with five Chinese medicinal materials including cassia seed, wolfberry fruit, mulberry, haw and safflower. has the functions of nourishing Yin, clearing away liver heat, promoting blood circulation, dredging the meridian passage; and is used mainly for treating hyperlipemia of kidney Yin deficiency and blood stasis.

The present invention relates to technology of medicinal preparation with component from plant in unknown structure, and is especially medicine comprising extract of 13 kinds of Chinese medicinal materials, including astragalus root, Dangshen, root of straight ladybell, ophiopogon root, arimonia herb. The medicine has reasonable recipe, modern preparation process, and the functions of benefiting vital energy, nourishing Yin, clearing away heat and toxic material, eliminating phlegm and relieving cough. It is suitable for the auxiliary treatment of vital energy and Yin deficiency and Yin deficiency internal heat type lung cancer in late stage, and has also high curative effect on shortness of breath, hypodynamia, cough, etc.

The present invention relates to an application of marine steroid YC-1 (24-methylene-cholesterol-3 beta, 5 alpha, 6 beta, 19-tetraol) in preparation of medicine for curing neuronal injury. It is characterized by that the oxysterol compound marine steroid YC-1 extracted from lip-softened coral of the Nansha Islands has protection action for several kinds of neuronal injuries, under the condition of effective protection dosage it does not produce toxic reaction. Said invention adopts a chemical synthesis method to make large-scale production.

The invention relates to a preparation method and new application of a polyinosinic preparation. Kanamycin and calcium ions are added on the basis of polyinosinic, so that the stability of polyinosinic double-stranded ribonucleic acid (RNA) is enhanced. Animal experiment results show that a polyinosinic complex has the effect of inhibiting tumor growth.

The invention discloses a traditional Chinese medicinal preparation for treating halitosis, which is prepared by using liquoric root, dried orange peel and tea leaves as raw materials. The traditional Chinese medicinal preparation has the characteristics of obvious treatment function, remarkable treatment effect, convenience for oral administration, no toxic and side effects and low price.

The invention belongs to the technical field of membrane type skin care products added with theabrownin and particularly provides anti-wrinkle oil-removing membrane type skin care products containing theabrownin and a preparation method thereof. The anti-wrinkle oil-removing membrane type skin care product is prepared from a theabrownin ethanol solution or theabrownin powder, citric acid and at least one membrane forming material. The preparation method comprises the steps that green tea is fermented through aspergillus niger to obtain a fermentation liquor rich in theabrownin, then the fermentation liquor is prepared into the theabrownin powder or the theabrownin ethanol solution, and finally the theabrownin powder or the theabrownin ethanol solution is fused with the membrane forming materials to prepare various membrane type skin care products. The oxidation resistance, oil removal and other functions of the theabrownin are utilized, the finished membrane type skin care products have the properties of preventing wrinkle forming, removing oil, lubricating the skin, resisting oxidation and the like. The products are low in cost, the preparation process is simple, the production cost is low, and the obtained membrane type skin care products are pure natural cosmetics, have obvious anti-wrinkle oil-removing moisturizing effects and have good market prospect.

The gout resisting Chinese medicine composition is prepared with alcohol extract of rhubarb in 90 weight portions and tetrandra root in 30 weight portions, water extract of plantain seed in 60 weight portions, oriental water plantain in 60 weight portions and achyranthes root in 60 weight portions, and supplementary material in proper amount. The preparation process includes the steps of: weighing material in certain proportion; preparing tetrandra root extractum through crushing, twice alcohol reflux extraction, etc; preparing rhubarb filtrate through alcohol reflux extraction, etc; preparing mixed filtrate of plantain seed, oriental water plantain and achyranthes root through twice decoctions, etc; mixing the rhubarb filtrate and the mixed filtrate, decompression concentration and drying to obtain mixed extractum; mixing tetrandra root extractum with the mixed extractum and supplementary material, pelletizing, tabletting and encapsulating.

The invention discloses a medicament for treating children's epilepsy which is a capsule prepared from the following Chinese medicinal herbs (by weight portion): Arisaema cum Bile 10 parts, pseudostellaria root 10 parts, pinellia tuber 10 parts, anemone rhizome 15 parts, amber 3 parts, rhizome of Sichuan lovage 6, gastrodia elata 6 parts, poria cocos wolf 10 parts, dried tangerine peel 6 parts, Chinese olive 15 parts, ligumaloes 3 parts, bitter orange 6 parts and notopterygium root 6 parts.

The invention discloses traditional Chinese medicine emulsifiable plaster for treating eczema and a preparing method thereof. The effective components for preparing the traditional Chinese medicine emulsifiable plaster include, by weight, 10-30 parts of cicada slough, 3-13 parts of cortex moutan carbonisatum, 5-25 parts of cynanchum paniculatum, 10-30 parts of sophora flavescens, 5-20 parts of radix puerariae, 30-50 parts of aloe vera gel, 3-18 parts of liquorice, 8-24 parts of Chinese angelica, 10-30 parts of portulaca oleracea, 5-15 parts of folium mori, 5-15 parts of wild chrysanthemum, 8-24 parts of prunella vulgaris, 10-20 parts of borneol, 2-18 parts of cortex dictamni, 5-20 parts of mint, 5-20 parts of notopterygium incisum, 4-16 parts of oriental wormwood, 5-20 parts of belvedere fruit, 10-30 parts of natural indigo, 30-60 parts of beewax and 30-50 parts of eucalyptus oil. The traditional Chinese medicine emulsifiable plaster is obtained through preparing of extractive powder, preparing of Chinese herbal medicine ultra-fine powder, emulsifying and mixing. The components do not include toxic substances or rare animals and are free of toxic reactions and irritation, low in price and capable of being used for a long time, the therapeutic principles that heat and toxic materials are cleared away, blood is nourished, wind is expelled, dampness is eliminated and itching is relieved are achieved, the current problems are resolved, the root is eliminated, the curative effect is definite, and the effective rate reaches up to 100 percent.

The invention relates to a medicament for treating pharyngitis, which is prepared from the following medicaments in part by weight: 1 to 3 parts of dregea sinensis, 1 to 2 parts of baical skullcap root, 1 to 2 parts of common alstonia leaf and 0.5 to 1 part of liquoric root. The medicament has reasonable compatibility, acute toxicity tests prove that the medicament has no toxic response, safe and reliable curative effects, good formulations and mouthfeel, and effects of improving local curative effect because of buccal administration, clearing heat and detoxifying, relieving sore throat and downbearing counterflow, and relieving cough and reducing sputum. The clinical curative effect observation and acute toxicity research prove that the medicament has the advantages of no toxic or side responses, and safe and reliable curative effects and is suitable for preventing and treating diseases such as acute and chronic pharyngitis, stomatitis, gingivitis, toothache due to wind-fire evil and allergic cough.

The invention discloses a houttuynia cordata scalding spray film agent and a preparation method thereof. The houttuynia cordata scalding spray film agent is characterized by comprising, by weight, 75-100 parts of houttuynia cordata mixing leach liquid, 3-5 parts of borneol and 50 parts of polyvinylpyrrolidone. The preparation method of the houttuynia cordata scalding spray film agent is characterized by including the following processing steps that (1) leach liquid is prepared; (2) 50-part polyvinylpyrrolidone is weighed, the polyvinylpyrrolidone is added into the houttuynia cordata mixing leach liquid, and even stirring is carried out; (3) after the borneol with the parts by weight being 3-5 parts is dissolved by ethyl alcohol, the mixed liquid is added into the solution obtained in the step (2), even mixing is conducted, and the houttuynia cordata scalding spray film agent is obtained. According to the houttuynia cordata scalding spray film agent and the preparation method thereof, the method is simple and convenient, the houttuynia cordata scalding spray film agent obtained through preparation can be used for treatment of burning and scalding quickly and effectively, skin allergy is avoided, toxic reaction can not occur to skin, stability is good, and production cost is low.