Traditional Chinese medicine compound formulation for treating dysmenorrhea as well as preparation method and use of formulation

A technology of compound preparations and traditional Chinese medicines, which is applied in the direction of medical formulas, non-central analgesics, medical preparations containing active ingredients, etc., and can solve the problems of inaccurate specific curative effect, difficult to determine quality standards, and backward technology

Active Publication Date: 2014-04-23
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, although there are some external preparations clinically, they are all clinical reports, the specific curative effect is not exact,

Method used

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  • Traditional Chinese medicine compound formulation for treating dysmenorrhea as well as preparation method and use of formulation
  • Traditional Chinese medicine compound formulation for treating dysmenorrhea as well as preparation method and use of formulation
  • Traditional Chinese medicine compound formulation for treating dysmenorrhea as well as preparation method and use of formulation

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0015] Example 1

[0016] Weigh 3000g of safflower, 3000g of frankincense, 3000g of myrrh, 3000g of turmeric, 3000g of cassia twig, 4000g of Dalbergia odorifera, 1000g of dragon's blood, 3000g of aconite, 3000g of Yuanhu, 2000g of wormwood, 2000g of asarum, 500g of borneol, and Babu Matrix 5500g. Process flow chart such as figure 1 As shown, take the remaining medicinal materials except borneol, add 8 times the amount of water to extract twice, 1 hour each time, filter the extract, and concentrate under reduced pressure to 6kg of extract for use; take borneol and crush it through an 80-mesh sieve for use; Add borneol to the extract extract, put it into the cataplasm base, stir evenly, coat and slice 1,000 pieces, and pack to obtain a pain relief patch for use. The finished product is yellow-brown to brown flake-shaped cataplasm, which is fragrant.

Example Embodiment

[0017] Example 2

[0018] Weigh 900g of safflower, 900g of frankincense, 900g of myrrh, 900g of turmeric, 900g of cassia twig, 1200g of odorifera, 300g of dragon's blood, 900g of aconite, 900g of Yuanhu, 900g of wormwood, 600g of asarum, 600g of borneol, cataplasma Matrix 1800g. Process flow chart such as figure 1 As shown, take the remaining medicinal materials except borneol, add 8 times the amount of water to extract twice, 1 hour each time, filter the extract, and concentrate it under reduced pressure to 2.5kg of extract for use; take borneol and crush it through an 80-mesh sieve for use ; Add borneol to the extract extract, put it into the cataplasm matrix, stir evenly, coat and slice 350 pieces, and pack it to get a pain relief patch for use. The finished product is yellow-brown to brown flake-shaped cataplasm, which is fragrant.

Example Embodiment

[0019] Example 3

[0020] Weigh 800g of safflower, 800g of frankincense, 800g of myrrh, 800g of turmeric, 800g of cinnamon sticks, 800g of odorifera, 500g of dragon's blood, 800g of aconite, 950g of Yuanhu, 500g of wormwood, 500g of asarum, 475g of borneol, and cataplasm Matrix 1500g. Take the remaining medicinal materials except borneol, add 8 times the amount of water to extract twice, 1 hour each time, filter the extract, and concentrate under reduced pressure to 2kg of extract for use; take the borneol and crush it through an 80-mesh sieve for use; Add borneol to the extract, put it into the cataplasm base, stir evenly, coat and slice 300 pieces, and pack to obtain the pain relief patch for use. The finished product is yellow-brown to brown flake-shaped cataplasm, which is fragrant.

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Abstract

The invention discloses a traditional Chinese medicine compound formulation for treating dysmenorrhea. The traditional Chinese medicine compound formulation is prepared from the following crude drugs in parts by weight: 1-15 parts of flos carthami, 1-15 parts of olibanum, 1-15 parts of myrrh, 1-15 parts of rhizoma wenyujin concisum, 1-15 parts of cassia twig, 1-15 parts of lignum dalbergiae odoriferae, 1-9 parts of resina draconis, 1-15 parts of lindera aggregate, 1-18 parts of rhizoma corydalis, 1-9 parts of folium artemisiae argyi, 1-9 parts of as arum and 0.5-9 parts of borneol. By adopting the traditional Chinese medicine formulation, the twister reaction times of dysmenorrhea model rats can be obviously reduced, uterine contractions rhythm disorders can be coordinated by adjusting the balance of prostaglandin level inside a sufferer body by inference, meanwhile, the neuropeptide P substance level is reduced by interaction between the systems in an immune neural network, and proinflammatory cytokines such as 1L-1beta are reduced, so as to achieve the target of treating dysmenorrhea. The invention also discloses a preparation method and use of the traditional Chinese medicine compound formulation.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating dysmenorrhea; in addition, the invention also relates to a preparation method and a medical application of the traditional Chinese medicine compound preparation. Background technique [0002] Primary Dysmenorrhea refers to cramping pain in the lower abdomen and waist before and during menstruation, accompanied by nausea, vomiting, and cold extremities in severe cases, and without obvious pelvic organic diseases (such as endometriosis) Wait). It is more common in unmarried or childless young women. The incidence rate of primary dysmenorrhea is 43% to 90% in foreign reports, and 33.19% in domestic reports, of which primary dysmenorrhea accounts for 36.06%. In addition, 80% of patients with endometriosis are accompanied by dysmenorrhea and chronic pelvic pain. Among them, progressively aggravated dysmenorrhea seriously affects the quality of life of female patients....

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/70A61P15/00A61P29/00
Inventor 蔡小荪付金荣
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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