74 results about "Digestants" patented technology

The invention relates to the technical field of data management, in particular to a self-service enema method and system based on intelligent proportioning, and the method comprises the following steps: collecting intestinal tract and physiological data, monitoring intestinal tract movement frequency, intestinal wall tension, instantaneous pressure, digestive juice secretion rate, heart rate and blood pressure in real time, removing abnormal data, and adjusting the data range. And forming a physiological parameter data set. According to the method, a refined data set is constructed by monitoring multiple physiological data in real time, so that the liquid medicine proportion better conforms to the individual characteristics, flow rate correction and pressure adjustment are introduced in the liquid medicine mixing process, it is ensured that the proportion is accurate and liquid medicine conveying is stable, and real-time pressure monitoring and excrement flow state analysis help to optimize the conveying rate and improve the liquid medicine absorption efficiency; the influence of individual difference is reduced, so that the accuracy and the effect of treatment are enhanced.

The invention discloses a digestible quality analysis system for chicken feed, relates to the technical field of chicken feed analysis, and aims to solve the problem of poor simulation effect of digestion of the chicken feed. According to the method, low-temperature and high-temperature staged drying treatment is adopted, the characteristics of components such as moisture and fat in the residues are fully considered, the secretion rules of different alimentary canal parts of animals are simulated, sufficient and reasonable contact of digestive juice and feed is ensured, the simulation process is closer to the real physiological condition, and the situation that the digestion analysis result is affected by liquid amount errors is avoided; animal digestive tracts are scientifically segmented into stomach, small intestine and large intestine stages, corresponding external buffer solution and internal digestive juice are injected respectively, and a real digestion scene is comprehensively simulated from a physical structure to a chemical environment.

The invention belongs to the field of food nutrition and functional factors, and particularly relates to a method for preparing ovotransferrin hydrolysate with high immunocompetence based on an adult gastrointestinal simulated digestion system. According to the method, ovotransferrin is treated through the stomach and intestine of a simulated adult, OVT hydrolysate is prepared, and the OVT hydrolysate contains HTEGSTT, TTSY and / or RTAGWVIPMG. The invention finds that the immunomodulatory activity of OVT is enhanced after gastrointestinal digestion and hydrolysis, the OVT is more easily hydrolyzed in simulated adult digestive juice than in infant digestive juice, and a contrast experiment shows that the nutrition intervention of OVT adult and infant simulated digestion products can promote the generation of short-chain fatty acids such as acetic acid, propionic acid and butyric acid; the swelling injury caused by inflammation to small intestine mucous membrane tissues is effectively relieved, so that the intestinal barrier immune function is obviously improved, and the OIA shows higher intestinal immune activity than the OIB.

The utility model discloses an instrument for preventing gas, digestive juice and tumor from entering the abdominal cavity during endoscopic full-thickness surgery, which comprises a pipe sleeve, a ring enclosed by inner-layer metal wires and a ring enclosed by outer-layer metal wires are arranged at the front end of the pipe sleeve, the diameter of the ring enclosed by the inner-layer metal wires is smaller than that of the ring enclosed by the outer-layer metal wires, and the diameter of the ring enclosed by the inner-layer metal wires is smaller than that of the ring enclosed by the outer-layer metal wires. A ring defined by the inner-layer metal wires and a ring defined by the outer-layer metal wires are connected through a transparent film layer, the rear end of the pipe sleeve is connected with a handle, and the ring defined by the outer-layer metal wires is covered with an outer-layer film. The utility model not only can be embedded into the perforated part, but also can prevent gas, liquid and tumor in the tube cavity from entering the abdominal cavity.

The present invention provides a sampling capsule, which includes a housing, a partition member that is circumferentially and sealingly connected to the inner wall of the housing and divides the inner cavity of the housing into a sampling cavity and a device cavity, and an extraction assembly provided on the housing corresponding to the sampling cavity. The partition member has a through hole communicating the sampling cavity and the device cavity, and a waterproof and breathable membrane covering the through hole. In the sampling capsule of the present invention, by providing a waterproof and breathable membrane on the through hole communicating the sampling cavity and the device cavity, the gases in the sampling cavity and the device cavity are connected. After using a syringe to evacuate the sampling cavity through the extraction assembly, the sampling cavity and the device cavity simultaneously form a vacuum state. Therefore, before sampling, the sampling capsule can maintain a vacuum state for a long time. Thus, during sampling, there is a sufficient pressure difference inside and outside the sampling capsule, and an expected amount of digestive juice can be obtained.

The invention relates to a preparation method of a placenta trophoblast-derived transporter and application of the placenta trophoblast-derived transporter in a medicine for treating spontaneous abortion, which comprises the following steps of: taking out a placenta of a suckling mouse, cutting the placenta into fine tissue blocks, resuspending by using digestive juice, digesting in a water bath kettle at 37 DEG C for 20 minutes, and then stopping digestion by using 1640 culture containing high-temperature heat-inactivated fetal calf serum; diluting and neutralizing collagenase digestive juice according to 5 times of volume; and centrifuging the collagenase digestive juice for multiple times to obtain a precipitate, namely the exosome. And carrying out density gradient centrifugation on the coarse migration body by using Optiprep as a density medium, washing, precipitating and centrifuging by using PBS on an ultra-high-speed centrifuge by using a horizontal rotor to obtain the placental trophoblast source migration body. The invention finds that the generation of the placental trophoblast cell source migration body is related to the physiological process of pregnancy for the first time, and the placental trophoblast cell source migration body can enter the circulatory system and reach the placenta through in-vitro supplementation.

The utility model discloses a kind of gastric cavity plugging catheters of gastrostomy in the medical instrument technical field, the device increases plugging balloon and sealing clamping piece, can be held by inside and outside, hold stomach wall and skin to position the device, while plugging balloon seals and isolates the puncture of stomach wall inside gastric cavity, effectively avoid gastric juice to flow out, avoid gastric juice to overflow along the puncture and cause skin burning;Positioning baffle is also increased, can be unfolded inside duodenum, positioning baffle can position nutrition tube, avoid nutrition tube to slide and separate, can also effectively block pylorus, effectively avoid enteric digestive juice to enter stomach, and do not hinder gastric juice to flow into intestine normally, and by pressure relief port and pressure relief pipe, stomach is conveniently decompressed, effectively avoid that pressure is too high and nutrition liquid is refluxed to esophagus.

This utility model discloses a protective anal tube for rectal anastomosis after surgery, relating to the field of medical device technology. It solves the initial problem of the need to develop a protective anal tube for rectal anastomosis after surgery that has three-dimensional isolation, facilitates negative pressure drainage, and has a biological barrier function. The utility model includes a tube body with two support members on it for supporting the intestine. Both support members are capable of mechanical deformation, and the contact surfaces between the two support members and the intestine are annular, which can support both sides of the intestinal anastomosis. Thus, a cavity is formed between the two support members and the anastomotic segment of the intestine. The purpose is that the two support members form a physical barrier through the annular contact surfaces, completely preventing the leakage of intestinal contents into the anastomotic area, avoiding contamination of the wound by feces and digestive juices, maintaining a moist environment, and promoting the migration of epithelial cells and the growth of granulation tissue.

The Endoscopic Adjustable Gastric Barrier represents a groundbreaking innovation in the management of obesity, offering a unique, minimal invasive approach without the complications and limitation of other currently available interventional managements., this revolutionary technique works by dividing the stomach into a smaller, tube-like space for food, without altering the stomach's natural anatomy or functions. This preserves the stomach's function to produce hormones and digestive juices, while effectively reducing food intake hence significant weight loss. What makes this innovation (EAGB) unique is its adjustability and reversibility, and when ideal weight is achieved it can be removed endoscopically. It is secured to the stomach by clips with minimal injury and without risk of necrosis and leak. Additionally, all endoscopic and laparoscopic interventions are possible as normal population.

To provide a method for quantitatively evaluating the progress degree of digestion of food.SOLUTION: A stomach body constituting the stomach model device is filled with artificial digestive juice, food is put therein, the stomach model is made to perform a movement similar to the peristaltic movement of the stomach, and a color moving image of the digestive state of the food with time in a specific range is photographed. Then, texture analysis (average value of luminance, variance of luminance, contrast of luminance, skewness of luminance, kurtosis of luminance, energy of luminance, entropy of luminance) is performed on the captured image to quantify the digestion state.SELECTED DRAWING: Figure 1

The present invention provides a self-assembling peptide gel for use in preventing a leak of digestive fluid and a self-assembling peptide gel for use in protecting an organ against digestion by a digestive fluid. The self-assembling peptide gel comprises a self-assembling peptide and water, whereby the self-assembling peptide gel has an adhesion persistence ratio with respect to a collagen sheet of at least 40% and a decomposition ratio of 35% or less in pancreatic juice treatment at 37°C for 7 days, and the self-assembling peptide gel is positively charged as a whole.

The invention discloses a dynamic bionic stomach digestion model and application thereof in micro-plastic detection.The dynamic bionic stomach digestion model comprises a box body, a fixing plate, an artificial stomach model, rolling wheels, a pylorus squeezing plate, a pH meter, a heating mechanism, a gastric acid solution cavity, a gastric juice solution cavity, a peristaltic pump and a micro-dialysis probe, and the rolling wheels are rotationally arranged on the fixing plate and located on the periphery of the outer surface of the artificial stomach model; the pylorus extrusion plate is movably arranged on the fixing plate and located on the outer side of the lower end of the artificial stomach model so as to extrude the lower end of the artificial stomach model, and the gastric acid solution cavity and the gastric juice solution cavity are communicated with the upper end of the artificial stomach model through the peristaltic pump. The method comprises the following steps: adding an aged biofilm-loaded micro-plastic sample or a micro-plastic sample loaded with heavy metal and the like and agar balls into an artificial stomach model, digesting in the artificial stomach model, detecting discharged liquid, solids and the like after digestion is completed, detecting the concentration change of digestive juice, micro-plastic particles and micro-plastic precipitates on agar ball particles, and determining the concentration change of the micro-plastic precipitates on the micro-plastic particles and the agar balls. Product identification and the like.

The utility model discloses a device suitable for fat stromal cell extraction, which comprises a bag body, the bag body internally comprises at least a first accommodating cavity and a second accommodating cavity, the first accommodating cavity is used for filling cleaning fluid, and the second accommodating cavity is used for filling digestive juice; the liquid inlet pipe is connected with one side of the accommodating cavity I; the waste liquid pipe is connected with one side of the accommodating cavity I; the liquid outlet pipe is connected with one side of the first containing cavity. According to the device, the fat matrix can be directly cleaned and digested in the same device suitable for extracting the fat matrix cells, an operator does not need to add cleaning liquid and digestion liquid, operation steps are reduced, and cross contamination can be effectively avoided.

The present invention provides a material or method that can serve as an alternative to a related-art digestive fluid leak preventative material and method of preventing a leak of a digestive fluid. The digestive fluid leak preventative material of the present invention includes a self-assembling peptide gel, has an adhesion persistence ratio with respect to a collagen sheet of at least 40%, and has a decomposition ratio of 35% or less in pancreatic juice treatment at 37°C for 7 days.

This invention belongs to the field of food nutrition and functional factors, specifically relating to a method for preparing highly immunomodulatory ovotransferrin (OVT) hydrolysates based on an adult gastrointestinal simulated digestive system. The method involves processing OVT using a simulated adult gastrointestinal tract to prepare OVT hydrolysates containing HTEGSTT, TTSY, and / or RTAGWVIPMG. This invention reveals that OVT exhibits enhanced immunomodulatory activity after gastrointestinal digestion and hydrolysis, and is more readily hydrolyzed in simulated adult digestive fluids than in infant digestive fluids. Comparative experiments show that nutritional intervention with OVT simulated digestive products from adults and infants can promote the production of short-chain fatty acids such as acetic acid, propionic acid, and butyric acid, effectively alleviate swelling and damage to the small intestinal mucosa caused by inflammation, significantly improve intestinal barrier immune function, and OVT IA exhibits higher intestinal immune activity than OVT IB.

The utility model discloses a retraction-free small intestine stoma tube, which relates to the technical field of medical instruments and is characterized by comprising an outer sleeve, main catheter supporting blocks are fixedly mounted at four corners of the inner wall of the outer sleeve, the main catheter supporting blocks are trapezoidal, and the length direction of the main catheter supporting blocks is consistent with the axial direction of the outer sleeve. A main catheter is fixedly installed on the side, away from the inner wall of the outer sleeve, of the main catheter supporting block, and the main catheter extends in the axial direction of the outer sleeve. The disposable stoma tube is simple in structure and convenient to use, effectively prevents the problem of unsmooth excrement flow turning caused by displacement, reduces the leakage risk of an anastomotic stoma, achieves smooth flow turning of digestive juice and excrement, avoids the trouble that a traditional stoma tube needs a secondary operation, remarkably improves the postoperative living quality of a patient, and reduces economic and mental burdens.

The invention discloses an application of a nutritional composition in preparation of an immunoregulation product. The nutritional composition comprises a lactoferrin gastrointestinal digest and a selenium gastrointestinal digest, wherein in the nutritional composition, the content of the lactoferrin gastrointestinal digests is 80 to 180 [mu] g / mL; in terms of selenium element, the content of selenium gastrointestinal digests is 12-28 ng / mL. The nutritional composition provided by the invention contains digestive juice compounded by lactoferrin and selenium, and compared with single lactoferrin and selenium, the nutritional composition has a better synergistic anti-inflammatory effect.

The utility model provides a novel tissue digester which comprises a digester shell and a sealing cover, a first chamber partition plate and a second chamber partition plate are installed in the digester shell, a tissue digestion chamber is formed between the first chamber partition plate and the second chamber partition plate, and a tissue digestion liquid channel is installed on the left side of the second chamber partition plate in a communicated mode. The left side of the first chamber partition plate is communicated with a cell suspension channel with a baffle, the interior of the first chamber partition plate is communicated with a filter screen, the filter screen is aligned with an input port of the cell suspension channel with the baffle, two sealing strips are installed below the sealing cover, and cover buckles are installed on the front side, the rear side, the left side and the right side of the sealing cover respectively. According to the method, digestion of released cells can be terminated, the activity of the cells is kept, tissue digestion is not affected, the cells can be continuously released, the effective digestion time is far longer than t, and the number and quality of the finally obtained cells are greatly improved.

The utility model relates to the technical field of gastrointestinal department medical instruments, in particular to a digestive juice filtering and reinfusion device which comprises a shell, an input pipe and an output pipe, the input pipe and the output pipe are communicated with the interior of the shell, a filter plate and a partition plate are arranged in the shell to divide the interior of the shell into an input cavity, a middle cavity and a reinfusion cavity in sequence, and the input cavity is communicated with the input pipe. The middle cavity is communicated with the output pipe, the middle cavity is externally connected with a negative pressure device, the partition plate is provided with a valve, the valve has an opening state and a closing state, when negative pressure is formed in the middle cavity, the valve maintains the closing state, and when hydraulic pressure in the middle cavity is larger than acting force needed by closing of the valve, the valve is opened so that the middle cavity and the feedback cavity can be communicated. The problems that an existing digestive juice filtering and returning device is relatively complex in structure and relatively troublesome to use are solved.

This invention discloses an internet-based digestive tract sampling capsule, comprising a capsule body with a placement cavity inside. The placement cavity houses a chip, a power supply, and a locator. The power supply provides power to the chip and locator. The locator is connected to the chip and can send location information to the chip. The chip can interact with external devices. The capsule body has multiple liquid-containing chambers arranged longitudinally. A liquid channel is formed on the left wall of each liquid-containing chamber, and a digestive fluid plug is placed within the liquid channel. A sealing plate is located on the left side of the digestive fluid plug, sealing the liquid channel. The chip can control the sealing plate to open the liquid channel. This device can locate the capsule's position and, through a combination of active and passive sampling methods, can achieve precise location identification and ensure a high sampling success rate.

The invention provides a preparation method of a probiotic microcapsule with high stress resistance, and belongs to the field of foods, pharmaceutical preparations or feeds. The microcapsule prepared by the preparation method has excellent technical effects of excellent high temperature resistance and digestive juice resistance, capability of protecting a core material from being inactivated in a spray drying process, high embedding rate, difficulty in disintegration in simulated gastric acid, good slow-release effect in simulated intestinal juice and the like; and the stability of the probiotics which have heat sensitivity and are not resistant to digestive juice is improved.

The application discloses a kind of for skin source fermentation food flavour substance dynamic evaluation method and bionic digestion device.The bionic digestion device includes bionic stomach module and flow path system, bionic stomach module is connected with flow path system;Bionic stomach module is connected with gastric emptying regulation module by flow path system;Gastric emptying regulation module is connected with bionic small intestine module, and the digestion product in bionic stomach module is transported to bionic small intestine module to simulate gastric emptying process;Digestion liquid supplement module is connected with bionic stomach module and bionic small intestine module;Detection module is installed in bionic stomach module, gastric emptying regulation module, bionic small intestine module and flow path system;Sampling module is connected with flow path system, and the side deviating from flow path system is connected with flavour response detection unit.By establishing continuous bionic digestion system, the simulation degree of bionic digestion system to human real digestion process is improved, and the continuous evaluation of flavour change of skin source fermentation food in digestion process is realized.

The application discloses a postoperative digestive juice filtering and returning device for abdominal surgery patients and belongs to the field of medical devices, which comprises a filtering and storing cylinder, a diluting cylinder, a returning cylinder, a piston one and a piston two, the diluting cylinder is arranged on the side of the storing cylinder, the returning cylinder is arranged on the side of the diluting cylinder, the piston one is slidably arranged in the diluting cylinder, and the piston two is slidably arranged in the returning cylinder. The application can finely adjust the returning efficiency, dilute the viscosity of different digestive juice original solutions, and sequentially and gradually return the digestive juice of the abdominal surgery patients. Compared with the traditional mode, the application can meet the returning requirements of different patients and different situations as much as possible, finely adjusts the postoperative nursing process, reduces the discomfort of the patients, and improves the recovery efficiency.

1. The name of the design product: portable sustained negative pressure drainage ball. 2. The use of the design product: to create a negative pressure environment, commonly used for active drainage, sputum, chest effusion, absorption of exuded blood and secretions, and retention of digestive juice in the gastrointestinal tract. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1.

The present invention discloses a method and application for encapsulating tributyrin with a hydrophilic barrier layer to aid probiotics in encapsulating tributyrin, belonging to the field of oil microencapsulation technology. The method comprises the following steps: 1) mixing probiotic cells with tributyrin and washing with an aqueous solution to obtain a first complex containing probiotics encapsulating tributyrin; and 2) mixing the first complex with a hydrophilic solution to obtain a second complex containing probiotics encapsulating tributyrin with a hydrophilic barrier layer. The second complex (tributyrin-encapsulated complex) prepared using the present method exhibits high loading capacity, lacks surface oil, and completely masks the odor of tributyrin. It can release tributyrin in digestive fluids and exert intestinal health benefits. It can be used in food, medicine, and feed, as well as in oral or parenteral formulations.

The absorbable gastrointestinal hemorrhage hemostasis tube comprises a first composition and a second composition, the first composition comprises polypeptide capable of being self-assembled in a water phase, and the second composition comprises methacrylamide gelatin (GelMA) and a photoinitiator; the polypeptide comprises 1-2 fragments R1 and 2-4 fragments R2, wherein the fragment R1 is connected to the N end or the C end of the fragment R2 or between the two fragments R2 through an amido bond; wherein the amino acid sequence of the fragment R1 is FLIVGSII. By means of various digestive enzymes in the digestive tract, different pH value environments and the scouring effect of fluid, the hemostasis tube can keep stable and play a role in the environments. For example, the structures and properties of polypeptides and GelMA enable them to resist the decomposition of digestive juice, maintaining their structural integrity of hemostasis in a dynamic environment within the digestive tract until the hemostasis process is completed and absorbed.

The invention discloses gel for digestive tract wound covering and a preparation method thereof, and belongs to the technical field of gel materials, the gel comprises the following components by weight: 0.01%-0.5% of cationic polysaccharide, 0.5%-20% of a film forming component, and 79.5%-99.5% of an auxiliary material. The gel can be used as a physical barrier to be adhered to the surface of a digestive tract when aiming at a wound surface generated in an endoscopic surgery, so that the flushing of digestive juice in the digestive tract to the wound surface is effectively prevented, the adhesion is avoided, the long-term slow release of the cationic polysaccharide is maintained, the wound healing is promoted, and the bleeding is quickly stopped.

The invention belongs to the technical field of food nutrition and digestion, and particularly relates to slowly digestible protein gel as well as a preparation method and application thereof. The preparation method of the slowly digestible protein gel mainly comprises the following steps: dissolving protein in water, adding iota-carrageenan or iota-carrageenan oligosaccharide, dissolving, adjusting the pH value, heating in a water bath, and cooling to obtain the slowly digestible protein gel. In the preparation method, the dosage of iota-carrageenan and iota-carrageenan oligosaccharide is relatively low, an acid inducer does not need to be used, the operation is simple and convenient, the production cost is low, and the safety is relatively high. The slowly digestible protein gel prepared by the preparation method has relatively low protein digestibility in gastric digestive juice and intestinal digestive juice, and can be used for preparing products for delaying gastric emptying and promoting satiety.

The application provides an article information pushing method combining article attributes and user preferences, comprising: obtaining digestive system disease types, digestive tract absorption capacity, digestive fluid secretion conditions and physiological characteristic data related to digestive function of a plurality of users, grouping the users through a clustering algorithm to obtain user groups with different digestive function characteristics; obtaining dosage form, particle size and surface area attribute information of health products, reducing the dimensions of the health products through principal component analysis according to disintegration time, dissolution rate and osmotic pressure characteristics of the dosage form to obtain a key attribute set of health products with different dosage forms; obtaining health product information searched by the user and digestive condition data of the user, and judging whether the user belongs to a group with weak digestive tract absorption capacity or a group with normal digestive function according to a set digestive threshold.

The application provides a kit and a method for determining the metabolic energy of fast-growing broiler feed by biomimetic digestion, which comprises digestive enzyme I, digestive enzyme II, buffer I, buffer II and trichloroacetic acid. The method comprises the following steps: preparation of a simulated digestion solution and a buffer; preheating and sample loading; stomach simulation digestion; small intestine simulation digestion; cleaning of hydrolysis products; treatment of undigested residues; and calculation of the digestion energy value. The kit and the method provided by the application can realize rapid and accurate determination of the metabolic energy value of fast-growing broiler feed.