The invention discloses a
traditional Chinese medicine composition for treating
skin diseases and a preparation method of the
traditional Chinese medicine composition. The
traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 6-12 parts of radix notoginseng, 8-15 parts of radix salviae miltiorrhizae, 10-20 parts of rhizoma chuanxiong, 8-15 parts of rhizoma curcumae longae, 15-35 parts of radix angelicae sinensis, 3-8 parts of
sandalwood, 3-8 parts of
fructus aurantii immaturus, 40-60 parts of ramulus cinnamomi, 8-15 parts of rhizoma
corydalis, 8-15 parts of rhizoma curcumae, 2-5 parts of
flos carthami, 5-12 parts of radix puerariae, 8-15 parts of radix rehmanniae, 3-8 parts of
pericarpium citri reticulatae and 8-15 parts of spica prunellae. The traditional Chinese
medicine composition is prepared from 3-8 parts of
radix trichosanthis, 15-35 parts of
tribulus terrestris, 15-35 parts of
cicada slough, 5-12 parts of stiff silkworm and 8-15 parts of rhizoma drynariae. According to a multi-target collaborative mechanism,
network pharmacology proves that 12
pathological pathways such as IL-17A and the like can be regulated and controlled, and the TNF-alpha inhibition rate is 89% and the barrier repair speed is increased by 2.3 times through key component combination. According to a transdermal synergistic technology, the specific surface area of the
medicine reaches 8.5 m < 2 > / g through
superfine grinding, a Franz test shows that the penetration amount of tanshinone is increased by 3.7 times, and the onset time is shortened to 8.3 minutes. Dual scar regulation and control: the thickness of
scars in 12 weeks is reduced by half through TGF-beta3 up-regulation and alpha-SMA inhibition, and the collagen order degree is improved by 3.2 times.