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57results about How to "Injection volume is small" patented technology

Quick detecting tube for micro-hydrogen sulfide gas

The invention relates to a detecting tube for low concentration hydrogen sulfide gas. Barium sulfate, silica gel or a mixture of the barium sulfate and the silica gel is used as a carrier; lead acetate solution and barium chloride solution are used as developing agents; glycerine is used as a wetting agent; and different detection indicators are obtained by controlling the dry condition. The hydrogen sulphide gas samples with different concentrations are introduced into the detecting tube, and the content of the hydrogen sulfide gas is determined according to the difference of the color changeof the developing agents. The detecting tube has simple structure, fast analysis, low cost and convenient carrying, and can detect weather the content of hydrogen sulfide in air of environment is over-proof at the field. The application experiment proves that the detecting tube has higher sensitivity and substantially meets the requirements of national standard.
Owner:BEIJING UNIV OF CHEM TECH

Colloidal suspension of submicronic particles for carrying active principles and their mode of preparation

The invention concerns a suspension of biocompatible particles for carrying active principles. Said carrier particles are based on a double-block hydrophilic neutral polyaminoacid / hydrophobic neutral polyaminoacid copolymer. Said hydrophilic neutral polyaminoacid / hydrophobic neutral polyaminoacid particles are capable of combining in colloidal suspension in non-dissolved state, at least an active principle and of releasing same, in particular in vivo, in prolonged and / or delayed delivery. The invention also concerns a powdery solid from which are derived the carrier particles and the preparation of said solid and of said suspension of active principle based on hydrophilic neutral polyaminoacids / hydrophobic neutral polyaminoacids. Said carrier particles form spontaneously and in the absence of surfactants or organic solvents, stable aqueous suspensions. The invention also concerns the carrier particles in dry form, the method for preparing them, and pharmaceutical compositions (in dry form or suspension) comprising said carrier particles associated with an active principle.
Owner:FLAMEL TECHNOLOGIES

Instrument system suitable for synchronous on-line detection of adsorption spectrum and fluorescence spectrum

The invention discloses a system for synchronous on-line detection of adsorption spectrum and fluorescence spectrum. The system consists of a reciprocating plunger pump, a sample introduction device, an enrichment device, a detection cell, a light source, a spectrograph, an optical fiber, a computer and a data processing system, wherein the sample introduction device is provided with a six-way valve; a sample passes through the reciprocating plunger pump according to a predetermined time, enters an active carbon enrichment column through the six-way valve and is discharged after online enrichment; after finishing enrichment, the six-way valve is switched; an eluate enters the active carbon enrichment column through the six-way valve; an enrichment substance is washed and enters a flow cell and is discharged after spectrum detection is performed on the enrichment substance; the content of the sample is calculated based on the change of spectrum intensity; and the flow cell is integrally connected with five-way valve formed by a light source radiation optical fiber interface hole, an ultraviolet visible light optical fiber interface hole, a fluorescence spectrum optical fiber interface hole, a liquid inlet pipe hole and a liquid outlet pipe hole. The system realizes the on-line detection of the adsorption spectrum and the fluorescence spectrum; and an instrument has the characteristics of small volume, light weight, good reproducibility, convenient carrying, and fast sample treating speed, so the system has wide application fields.
Owner:XINJIANG MEDICAL UNIV

Wax-based blade coating patterning method

The invention discloses a wax-based blade coating patterning method which comprises the following steps: performing hydrophilic treatment on the surface of a plastic piece to serve as a substrate; designing a photonic crystal pattern or a pattern of a microfluidic channel, and printing the designed patterns on the substrate by using wax; performing blade coating on SiO2 photonic crystal colloid on the substrate printed with the photonic crystal pattern, so that the SiO2 photonic crystal colloid is poured into a hollow area without the wax; or performing blade coating on microcrystalline cellulose suspension subjected to acidolysis on the substrate printed with the microfluidic channel, so that the microcrystalline cellulose suspension subjected to acidolysis is poured into the hollow area without the wax; and volatilizing a solvent, and forming a SiO2 photonic crystal or a microfluidic chip. The used blade coating has the advantages that the operation is simple, and heating is not needed; the manufactured photonic crystal pattern has excellent optical properties with ordered structure and angle deflection and can be applied to manufacturing anti-counterfeiting patterns, and the manufactured microfluidic chip has the characteristics of high resolution ratio, high flow velocity, low sample consumption and the like and can be used for low-cost biochemical field detection.
Owner:SOUTHEAST UNIV

Microwave-electric chemical rapid heavy-metal detector and application thereof

The invention discloses a heavy-metal electric-chemical rapid detector, which comprises an electric-chemical analysis system and a microwave emitter, wherein the electric-chemical analysis system comprises a peristaltic pump, a work electrode, an assistant electrode, a reference electrode, a screening sleeve and an electrolytic cell, wherein the peristaltic pump is arranged between a sample to be detected and the reference electrode or the assistant electrode, the screening sleeve is arranged between the electrolytic cell and the reference electrode or the assistant electrode, the work electrode partially extends into the electrolytic cell, the part of the work electrode above the electrolytic cell is wrapped by the screening sleeve, and the assistant electrode and the reference electrode are arranged above the screening sleeve. The invention also discloses a heavy-metal electric-chemical detection system and a detection method of heavy metals in the sample.
Owner:EAST CHINA NORMAL UNIV +1

Quick detecting tube for micro-ammonia gas

The invention relates to a detecting tube for low concentration ammonia gas. Barium sulfate, silica gel or a mixture of the barium sulfate and the silica gel is used as a carrier; thymolsulfonphthalein and methylthymol blue are used as color reagents. The ammonia gas samples with different concentrations flow into the detecting tube; the content of the ammonia gas is determined by different colorsof the color reagents; and the detecting tube has simple structure, quick analysis, low cost and convenient to carrying, and can detect whether the content of the ammonia gas in the environmental airon-site is over-proof at the field. The application experiment shows that the detecting tube has higher sensitivity and substantially meets the requirements of national standard.
Owner:BEIJING UNIV OF CHEM TECH

Preparation method and application of cobalt oxide/mesoporous carbon composite material electrochemical sensor

The invention relates to the field of rapid detection of food safety and particularly relates to a preparation method and application of an electrochemical sensor based on a cobalt oxide / mesoporous carbon nanocomposite material and application of the electrochemical sensor in fast detection of nitrite content in a food. The preparation method of the electrochemical sensor comprises preparing a nanocomposite material carrying cobalt oxide particles and graphitized mesoporous carbon, and modifying a work electrode of the electrochemical sensor. The electrochemical sensor can detect a standard solution of nitrite, determine the linear relationship between the nitrite concentration and current, determine nitrite in the food and compare the nitrite content in the food and the linear relationship to obtain nitrite content of the food to be detected. The electrochemical sensor can determine nitrite content of a food, is easy to operate, has a fast detection rate and high detection sensitivity and provides a novel detection method for efficient and rapid detection of nitrite content in a food.
Owner:SHANGHAI OCEAN UNIV

Method for detecting content of homocysteine in blood or urine

The invention discloses a method for detecting the content of homocysteine in blood or urine. The method comprises the following steps: 1, respectively mixing a standard substance and a sample to be tested with an internal standard solution, adding a matrix solution, and uniformly mixing; 2, adding mercaptoethanol, dithiothreitol or TCEP (trichloroethyl phosphate), uniformly mixing, and allowing the obtained solutions to stand for 10min; 3, adding trichloroacetic acid with the mass percentage of 10%, centrifuging at a high speed, taking the obtained supernatants, diluting the supernatants by deionized water, carrying out liquid phase-mass spectrometry by respectively allowing the diluted supernatants and a mobile phase to flow through a chromatographic column, and finally determining the content of the homocysteine in the blood or the urine. The method for detecting the content of the homocysteine in the blood or the urine of the invention has the advantages of simplicity, rapidness and sensitivity, can be applied to the screening of a large amount of samples, and makes accurate quantification and strong specificity be realized.
Owner:郑州和合医学检验实验室有限公司

Low-molecular-weight heparin molecular weight and molecular weight distribution detection method

The invention relates to a low-molecular-weight heparin molecular weight and molecular weight distribution detection method. High performance liquid chromatography is used, the method includes the following steps that firstly, a low-molecular-weight heparin sodium standard substance solution is prepared; secondly, a low-molecular-weight heparin sodium molecular weight calibration standard solution is prepared; thirdly, a test sample solution is prepared; fourthly, a 0.01% sodium azide solution is prepared; fifthly, the 0.01% sodium azide solution, the low-molecular-weight heparin sodium standard substance solution, the low-molecular-weight heparin sodium molecular weight calibration standard solution and the test sample solution are injected into a high performance liquid chromatograph respectively to obtain a chromatogram, the molecular weight of a test sample is calculated and a molecular weight distribution result is obtained according to the chromatogram.
Owner:SHENZHEN TECHDOW PHARM CO LTD

Method for rapidly detecting content of EGCG in tea polyphenol

The invention belongs to the field of analytical chemistry, and particularly relates to an ultra-high performance liquid chromatography rapid detection technology, in particular to a method for efficiently and rapidly detecting the content of EGCG in tea polyphenol as a raw material by utilizing the ultra-high performance liquid chromatography detection technology. A C18 chromatographic column isadopted; water-glacial acetic acid-methanol with a certain proportion is used as a mobile phase; the content of the EGCG in the tea polyphenol is rapidly detected in a gradient elution mode; and the theoretical plate number of the EGCG under the chromatographic condition is greater than 16,000, and the separation degree is greater than 3. By adopting the detection method, the EGCG, EC and caffeinerelatively difficult to separate are effectively separated; and the method is short in detection time, high in sensitivity, good in reproducibility, efficient and rapid, and can be applied to the EGCG content detection and quality control.
Owner:广西轻工业科学技术研究院有限公司

High performance liquid chromatography method for analysis of alkyl chloride compound

The invention discloses a high performance liquid chromatography method for analysis of alkyl chloride compound. The analytical conditions are as below: chromatography column uses a polysaccharide coated chiral chromatographic column; a mixed solution containing a derivative reagent, a sample to be measured and a diluent is used as the solution to be measured; a first mixed solution containing a first organic solvent and a second organic solvent is used as a mobile phase; a mixed solution containing a first organic solvent and a second organic solvent is used as a diluent; and the first organic solvent is an organic hydrocarbon solvent, and the second organic solvent is an organic alcohol solvent. The method can fast and efficiently separate enantiomers of alkyl compounds, and effectively control of the quality of chiral acyl chloride compounds. The detection method has the advantages of high sensitivity, good repeatability, high accuracy, wide application range, low cost and convenient operation, and can effectively control the product quality.
Owner:WATERSTONE PHARMA WUHAN

Method for distinguishing tubercular meningitis and virus meningitis based on nuclear magnetic resonance technology and application thereof

The invention discloses a method for distinguishing tubercular meningitis and virus meningitis based on a nuclear magnetic resonance technology and application thereof. According to the method, nuclear magnetic resonance detection is conducted on the cerebrospinal fluid of a patient to be detected to obtain relative expression quantities of difference metabolites represented by chemical shifts of 3.50 ppm, 3.76 ppm, 3.05 ppm, and 2.79 ppm respectively, and then whether the patient suffers from the tubercular meningitis or the virus meningitis is distinguished according to the relative expression quantities of the difference metabolites. Compared with the prior art, the method has the advantages of being simple in sample treatment, free of sample damage, small in sample quantity, good in repeatability, low in cost and the like.
Owner:BEIJING CHEST HOSPITAL CAPITAL MEDICAL UNIV +1

Micro-fluidic chip for detecting glycosylated hemoglobin and detection method thereof

The invention provides a micro-fluidic chip for detecting glycosylated hemoglobin and a detection method thereof. The micro-fluidic chip is sequentially provided with a cover plate layer, a fluid layer with a hollow channel structure and a substrate layer from top to bottom, and the hollow channel structure and the substrate layer jointly form a sample detection unit. A sample injection through hole and a waste liquid leading-out through hole are respectively formed in the cover plate layer. The sample detection unit comprises one or more sample injection chambers, a dilution chamber, an affinity chromatography channel, a detection chamber and a waste liquid pool. The sample injection through hole is communicated with the sample injection chamber, and the waste liquid leading-out through hole is communicated with the waste liquid pool. Sample introduction, sample dilution and optical and electrical detection are integrated through the micro-fluidic chip; the operation process is greatly simplified, the consumption of samples and reagents is reduced, expensive equipment is not needed, the use cost is largely reduced, the on-site instant detection of glycosylated hemoglobin can be realized, and huge economic value and social value are created.
Owner:上海佰芯生物科技有限公司

Method for simultaneous rapid determination of content of nine kinds of alcohol compounds in edible flavors and fragrances by GC-MS method

The invention relates to a method for simultaneous rapid determination of the content of nine kinds of alcohol compounds in edible flavors and fragrances by a GC-MS method, and belongs to the field ofanalytical chemistry. According to the method for simultaneous rapid determination of the content of the nine kinds of the alcohol compounds in the edible flavors and fragrances by the GC-MS method,a gas chromatography-mass spectrometer is adopted, deuteration-1-propyl alcohol-1,1,3,3,3-d<5> is taken as an internal standard, split sampling at the ratio of 20 to 1 is carried out, temperature programming is carried out, and an SIM scanning model establishes the method for rapid determination of the content of the nine kinds of the alcohol compounds in the flavors and fragrances; by analyzing,the nine kinds of the alcohol compounds have a good liner range within 0.2-50 mg / L, the correlation coefficients are all 0.993 or above, the quantitative limit is within 0.65-1.01 mg / kg, the average recovery rate of a standard addition experiment is within 87.9%-105.2%, and the relative standard deviation is within 2.01%-4.83%; and results indicate that the method is simple, rapid and accurate, and is suitable for simultaneous analysis determination of the nine kinds of the alcohol compounds in the edible flavors and fragrances.
Owner:CHINA TOBACCO YUNNAN IND

Method for measuring chemical oxygen requirement by photoelectric concerted catalysis

A device to assay the chemical oxygen demand catalyzed by photoelectricity belongs to the environment analysis chemical and sensor technology field. The analyzing detection device which can receive the ultraviolet light irradiation and the working electrode with the photoelectricity co-catalyzing activity is be used with the traditional flow injecting sampling system and the data processing system. when the ultraviolet light illuminates the working electrode, the computer starts and controls the electrochemical workstation to give +1.1-+1.5V working potential on the working electrode. In the selective flow injecting analyzing condition, a quantity of water sample flow the working electrode, the workstation collects the current response signal of the working electrode which quantity the water chemical oxygen demand.
Owner:EAST CHINA NORMAL UNIVERSITY

Instrument system suitable for synchronous on-line detection of adsorption spectrum and fluorescence spectrum

The invention discloses a system for synchronous on-line detection of adsorption spectrum and fluorescence spectrum. The system consists of a reciprocating plunger pump, a sample introduction device, an enrichment device, a detection cell, a light source, a spectrograph, an optical fiber, a computer and a data processing system, wherein the sample introduction device is provided with a six-way valve; a sample passes through the reciprocating plunger pump according to a predetermined time, enters an active carbon enrichment column through the six-way valve and is discharged after online enrichment; after finishing enrichment, the six-way valve is switched; an eluate enters the active carbon enrichment column through the six-way valve; an enrichment substance is washed and enters a flow cell and is discharged after spectrum detection is performed on the enrichment substance; the content of the sample is calculated based on the change of spectrum intensity; and the flow cell is integrally connected with five-way valve formed by a light source radiation optical fiber interface hole, an ultraviolet visible light optical fiber interface hole, a fluorescence spectrum optical fiber interface hole, a liquid inlet pipe hole and a liquid outlet pipe hole. The system realizes the on-line detection of the adsorption spectrum and the fluorescence spectrum; and an instrument has the characteristics of small volume, light weight, good reproducibility, convenient carrying, and fast sample treating speed, so the system has wide application fields.
Owner:XINJIANG MEDICAL UNIV

Method for measuring chemical oxygen requirement by photoelectric concerted catalysis

A device to assay the chemical oxygen demand catalyzed by photoelectricity belongs to the environment analysis chemical and sensor technology field. The analyzing detection device which can receive the ultraviolet light irradiation and the working electrode with the photoelectricity co-catalyzing activity is be used with the traditional flow injecting sampling system and the data processing system. when the ultraviolet light illuminates the working electrode, the computer starts and controls the electrochemical workstation to give +1.1-+1.5V working potential on the working electrode. In the selective flow injecting analyzing condition, a quantity of water sample flow the working electrode, the workstation collects the current response signal of the working electrode which quantity the water chemical oxygen demand.
Owner:EAST CHINA NORMAL UNIV

Equipment for treating unsymmetrical dimethylhydrazine-containing wastewater

The invention relates to equipment for treating unsymmetrical dimethylhydrazine-containing wastewater. The equipment comprises a wastewater conveying mechanism, a flow detection mechanism, a concentration detection mechanism, a catalyst sampling mechanism, a degradation reaction mechanism and a control mechanism. The degradation reaction mechanism is respectively communicated with the wastewater conveying mechanism and the catalyst sampling mechanism through pipelines, and the degradation reaction mechanism is used for degrading unsymmetrical dimethylhydrazine in the wastewater; and the control mechanism is electrically connected with and controls the wastewater conveying mechanism and the catalyst sampling mechanism, and is used for adjusting the flow of the wastewater and the sampling amount of the catalyst according to the concentration of unsymmetrical dimethylhydrazine in the wastewater. When the concentration of unsymmetrical dimethylhydrazine in the wastewater is large, the flow of the wastewater can be properly reduced and the sampling amount of the catalyst can be increased, and on the contrary, the flow of the wastewater can be properly increased and the sampling amount of the catalyst can be properly reduced. Therefore, the unsymmetrical dimethylhydrazine amount treated in unit time in the degradation reaction mechanism is relatively stable, so that the fluctuation of each discharge index of the treated wastewater is relatively small.
Owner:TSINGHUA UNIV +1

UPLC/MS/MS detection method of 1-hydroxymidazolam concentration in liver microsome

InactiveCN105136962AImprove stabilityShorter Chromatography TimeComponent separationSpectrometerStandard curve
The invention discloses a UPLC / MS / MS detection method of the 1-hydroxymidazolam concentration in a liver microsome. The UPLC / MS / MS detection method comprises the following steps that 1, a liver microsome incubation system is established, serial concentrations of 1-hydroxymidazolam comparison products are added to prepare a standard curve sample; 2, the standard curve sample is injected into a UPLC / MS / MS liquid chromatograph / mass spectrometer for detection, and a standard 1-hydroxymidazolam curve is obtained according to the detection result; 3, a sample to be detected is prepared by adopting the same method as the step 1 and is injected into the UPLC / MS / MS liquid chromatograph / mass spectrometer, detection is performed under the same conditions as the step 2, and the 1-hydroxymidazolam concentration in the sample to be detected is obtained according to the standard curve. The UPLC / MS / MS detection method is short in analysis time, high in sensitivity and small in sample size, meets the methodological validation requirement, is suitable for determination of the 1-hydroxymidazolam concentration in the liver microsome incubation sample and has wide application prospect.
Owner:成都华西海圻医药科技有限公司

Method for determining endosulfan in feed by gas chromatography-tandem mass spectrometry

The invention discloses a method for determining endosulfan in a feed by gas chromatography-tandem mass spectrometry. The method comprises the following steps of pretreating a sample, and detecting; weighing a certain amount of sample, extracting the endosulfan in the sample by using an organic solvent (chromatographic pure acetonitrile) as an extracting agent, concentrating by a nitrogen blowinginstrument, purifying the concentrated liquid by a Florisil diatomite SPE (solid-phase extraction) column, and using the gas chromatography-tandem mass spectrometry to perform qualitative and quantitative treatment. The method has the advantages that the organic solvent (chromatographic pure acetonitrile) is used as the extracting agent, and the sample is concentrated, and purified by the Florisildiatomite SPE column, so that the pretreatment is simple and convenient, and the consumption time is short; the gas chromatography-tandem mass spectrometry adopts a MRM (multiple reaction monitoring)mode to determine, so that the sensitivity and precision are high, and the qualitative and quantitative treatment is accurate; the universality is strong, the method is suitable for the feed sampleswith different proportional ratios, and the requirement of quickly separating and detecting the endosulfan in the feed sample can be met.
Owner:淮安出入境检验检疫局综合技术服务中心

A method for quantitatively detecting the valence state and content of chromium in chromium-containing substances

ActiveCN105510494BOptimizing separation and detection methodsHigh speedComponent separationSmall sampleCentrifugation
The invention discloses a method for quantitative detection of chromium element valence and content in a chromium-containing substance. The method includes: adding a chromium-enriched yeast stem cell sample into an alkali digestive juice to conduct treatment, then performing centrifugation, adjusting the pH of conditioning fluid to obtain a to-be-detected solution; preparing a chromium standard solution, performing testing, and establishing a chromium stand solution standard curve; subjecting the to-be-detected solution to high performance liquid phase separation, using an inductively coupled plasma mass spectrometry to analyze the Cr(VI) content, conducting acid digestion, and directly using inductively coupled plasma mass spectrometry to analyze the total chromium content of the sample, calculating the Cr(III) content through the difference of the total chromium content and the Cr(VI) content of the sample. The method provided by the invention improves the accuracy of sample measurement, has the characteristics of small sample size and short detection time, saves the sample preparation amount and measurement time, can accurately and quantitatively measure chromium-enriched yeasts with different chromium enrichment amounts.
Owner:INST OF MICROBIOLOGY - CHINESE ACAD OF SCI

Determining method for polydimethylsiloxane in edible oil and meat products

The invention belongs to the field of analytical chemistry and specifically relates to a determining method for polydimethylsiloxane in edible oil and meat products. The determining method comprises the following steps: (1) sampling: weighing a defined amount of edible oil sample or meat product sample; (2) performing methyl esterification: adding a potassium hydroxide carbinol solution into the edible oil sample or meat product sample, spirally mixing and adding a defined amount of water; (3) extracting and separating: adding n-hexane, spirally mixing, transferring an n-hexane solution to a centrifuge tube, repeating the extraction and combining the extracting solutions at two times; (4) concentrating: concentrating the combined extracting solutions by blowing nitrogen, thereby obtaining a sample solution; and (5) analyzing and determining: qualitatively and quantitatively analyzing and determining the sample solution according to a pyrolysis gas-phase chromatography and mass spectrography method. The determining method provided by the invention has the beneficial effects that the polydimethylsiloxane in the edible oil and the meat products can be analyzed and determined; the determining method has the characteristics of high speed, strong selectivity, small pollution, low limit of detection, and the like; and the determining method has the advantages of small sampling amount, high analyzing speed, excellent reproducibility, and the like.
Owner:INNER MONGOLIA AUTONOMOUS REGION PROD QUALITY TEST INST

Method for detecting concentration of related substances in ibuprofen medicine based on ultrahigh liquid chromatography

The invention discloses a method for detecting the concentration of related substances in an ibuprofen drug based on ultrahigh liquid chromatography, and belongs to the technical field of analytical chemistry. According to the detection method, the related substances in the ibuprofen medicine are determined on the basis of high performance liquid chromatography; and the related substances such asimpurities C, impurities J, impurities M and impurities ibuprofen sorbitol ester in the ibuprofen medicine are qualitatively and quantitatively detected by adopting the ultra-high performance liquid chromatography, so that the analysis time of a sample can be shortened to 1 / 3 of that of an HPLC analysis method; impurities with different structures are separated and detected in a short time; the UPLC is provided with a low-diffusion and low-cross-contamination automatic sample injector, and is provided with an in-needle sample injection probe and a pressure-assisted sample injection technology,so that the detection method designed by the invention is more excellent in repeatability and stability, and can effectively detect impurities.
Owner:HUMANWELL PURACAP PHARM WUHAN CO LTD

Stabilized formulations containing Anti-angptl3 antibodies

The present invention provides stable pharmaceutical formulations comprising a human antibody that specifically binds to human angiopoietin-like protein 3 (ANGPTL3). The formulations may contain, in addition to an anti-ANGPTL3 antibody, a buffer; an organic cosolvent; at least one viscosity modifier, and optionally at least one amino acid. The pharmaceutical formulations of the present invention can be administered via intravenous infusion or subcutaneously and exhibit a substantial degree of antibody stability after storage for several months.
Owner:REGENERON PHARM INC

Excrement metabolite for detecting curative effect of active pulmonary tuberculosis and detection system thereof

The invention discloses a method for judging whether an active pulmonary tuberculosis patient to be detected is cured or not after being treated for 6 months by an antituberculosis drug standard basedon an excrement LCMS metabonomics technology. The method comprises the following steps: carrying out LCMS (Liquid Chromatography Mass Spectrometry) detection on excrement of a to-be-detected patientto respectively obtain relative expression quantities of 14 differential metabolites, and judging whether the to-be-detected patient is cured or not according to the relative expression quantities ofthe 14 differential metabolites. Compared with the traditional method, the method provided by the invention has the advantages of non-invasion, simple sample treatment, no damage to the sample, smallsample injection amount, good repeatability, low cost and the like.
Owner:广东省结核病控制中心

Chinese herbal medicine component preparation for treating asthma and preparing process and quality control method thereof

The invention relates to a Chinese herbal medicine component preparation for treating asthma and A preparing process and quality control method thereof. The preparation is prepared from Chinese herbal raw material medicines including Chinese holly, radix glehniae, radix salviae miltiorrhizae, licorice root, seabuckthorn, bitter almond and tabasheer. Extraction is conducted through different methods, and the capsule preparation is prepared; through reasonable compatibility and preferential preparation, the Chinese herbal raw material medicines are complementary in effect and have the effects of eliminating phlegm, relieving cough, opening the inhibited lung-energy, reliving asthma and safely and effectively treating the asthma; through the dosage form preparation process and quality control research, selectable dosage forms are increased for the compound clinical medication, and the medical value and economic value of the Chinese herbal medicine component are expected to be enlarged.
Owner:深圳弘汇生物医药有限公司

Stable liquid interferon formulations

Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.
Owner:BIOGEN IDEC MA INC
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