16 results about "Tissue Dissection" patented technology

The LNTPI is a surgical instrument used to cut through fibrotic and edematous tissue to define the natural tissue plane of dissection. After defining the natural tissue plane, it is designed to move or carefully insinuate tissues along these natural planes without cutting the tissue, so that targeted organs or parts thereof could be viewed and reached during laparoscopic procedures. The following features make the LNTPI unique compared to standard blunt dissectors used in laparoscopy: 1. The tip of the LNTPI is coarse and not smooth. The tip has diagonal, spiral ridges from the sides which are carried onto the tip converging as a single spiral at the center of the tip, creating a pattern resembling that of a screw; 2. The ridges of the LNTPI are comprised of asymmetrical triangular ridges with an acute angle at the apex that may be leaning along with or against the rotation of the spiral; 3. The tip of the LNTPI is made of tungsten carbide metal instead of stainless steel; 4. Dissection can be done in the usual up, down, left, and right motions as standard dissectors; 5. The side of the LNTPI can be used to "peel" tissue by using the ridges on its side combined with a twisting movement. This maneuver cannot be performed using standard dissectors; and 6. The tip of the LNTPI can perform circumferential dissection when used with a twisting movement causing it to engage tissue like a "drill" along the natural tissue plane. The ridges that converge into a single spiral at the tip of the invention appear like a screw and with the proper twisting movement have a similar effect on tissue. Because of the texture, design, and material used for the tip of the LNTPI, it has the following advantages over standard dissectors: The LNTPI can engage tissues more easily even if the tissues are slippery due to the presence of blood or fluids. The LNTPI can be used to engage tissues through a twisting motion which motion allows the tissues to be engaged in a specific manner that defines natural tissue dissection planes. The LNTPI can insinuate / "peel" tissue by using the side spiral ridges in combination with a twisting movement. The LNTPI can perform circumferential dissection by using the tip and the convergence of the spiral ridges at the center of the tip in combination with a twisting movement. The transfer of lateral shear force to the tissue at various angles (45, 90, and 180 degrees) when using the LNTPI is significantly higher whether the motion is by a sweeping motion or twisting of the instrument, allowing it to insinuate better than standard instruments, especially in a wet field. Hand movements needed in insinuating tissue using the LNTPI are different from the usual hand movements when using standard dissection instruments. The hand movements in using LNTPI require less muscular effort and repetitiveness, thus preventing muscle fatigue and repetitive use injury among surgeons. The instrument is reusable, as compared to dissectors that have fabric at the tip, which must be disposed of and replaced once the fabric tip fully absorbs the blood or other fluid in the wet tissue surface.

The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to a tissue traction device, e.g., for endoscopic tissue dissection. For example, a tissue traction device may include a first clip comprising opposable jaws. The device may include a traction band having a first end, a second end, a length therebetween and extending along a longitudinal axis. The band may have a first aperture at the first end. A second aperture may be at the second end of the band. A first jaw of the opposable jaws of the first clip may be disposed through the first aperture.

A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device including a flexible portion that is suited to access target anatomy. The flexibility of an elongate portion of the delivery device can be varied. Additionally, the delivery device can include structure that maintains the positioning of the delivery device in patient anatomy.

Devices, systems (100, 200), and methods for separating tissue by moving a material layer (140, 240) with respect to a tissue-separating end effector (110, 210). The material layer is moved over a contact surface (152, 252) of the tissue-separating end effector. Contact of the material and the contact surface with tissue, with the moving material moving with respect to the contacted tissue, causes separation of contacted tissue. The tissue-separating end effector may be considered a blunt tissue dissector.

A modular surgical device is disclosed for efficient tissue dissection and fluid evacuation during surgical procedures. The device comprises a first portion with a cutting end tapered to a sharpened tip, a fluidic channel, and a uniquely shaped aperture. The aperture features an elliptical cross-section oriented at an angle relative to the device's longitudinal axis, potentially enhancing fluid flow dynamics. A releasable locking assembly securely connects the first portion to a second handle portion containing a fluidic channel and an angled external port for evacuation hose attachment. The device's modularity allows for customization and its angled port configuration is designed to minimize interference during surgical procedures.

A histotripsy therapy system configured for tissue treatment, which may include any number of features, is provided. Systems and methods providing effective, non-invasive and minimally invasive therapeutic, diagnostic, and research procedures are provided herein. Systems and methods are provided to facilitate real-time monitoring of delivered dose and tissue dissection. Techniques may include monitoring received acoustic cavitation emission signals or using dMRI.

The cardiac valve tissue dissection device includes a housing having an elongated opening formed therein, a cutting guide arm pivotally connected to the housing by a hinge assembly, the cutting guide arm having a slot formed therein, and an actuator wire coupled to the cutting guide arm. Movement of the actuator wire causes the cutting guide arm to pivot outward from the housing. A cutting element including a blade with a sharp tip is coupled to a track link configured to move along a track within the housing. An actuation slider is coupled to the elongated element and movable through a passage within the housing. Movement of the actuation slider causes the track link and cutting element to move along the track. When the track link is at one end of the track, the blade does not protrude from the housing, and when the track link is not at that end of the track, the blade protrudes from the housing.

The invention relates to a method for generating ultrasonic cavitation and a tissue fragmentation robot system, and the method comprises the steps: carrying out the multi-modal image matching, and obtaining a fusion display image; marking an interested target area and a sensitive medium; extracting acoustic parameters of the multilayer medium, and calculating amplitude compensation values and phase compensation values of a plurality of array element driving signals; according to the tissue type, region division is carried out, and at least one of an inherent threshold value, impact scattering and a boiling cavitation region is included; cavitation focuses are arranged; different sound pressure and pulse parameters are set for the inherent threshold value, the impact scattering area and the boiling cavitation area; and generating ultrasonic cavitation at the position of one cavitation focus, and moving the ultrasonic transduction device to generate ultrasonic cavitation on the other cavitation focus until the ultrasonic cavitation of all the cavitation focuses is completed. Compared with the prior art, the method realizes diversification of ultrasonic emission modes, and has the advantages of high pulse emission precision, remarkable tissue fragmentation effect, small side effect, high cost effectiveness and high registration precision.

This invention discloses a device and method for creating a mouse model of chronic pancreatitis by impact, belonging to the technical field of animal experimental equipment. The device includes a vibration generator, a vibration rod, and a vibration head, and can also be equipped with an outer shell, levers, and a buffer sleeve. The vibration generator drives the vibration rod to generate high-frequency reciprocating vibrations in the vibration head. The vibration head is a miniature rigid structure with various end shapes such as spherical, spoon-shaped, and forceps-shaped. The outer shell enables tissue dissection, pancreatic clamping, and axial extension and retraction of the vibration head. The buffer sleeve blocks vibration transmission. The modeling method involves pre-setting the device parameters, exposing the pancreas through levers after abdominal incision, allowing the vibration head to contact the target area and initiate high-frequency vibration to complete the modeling. This device achieves precise targeted stimulation of the mouse pancreas, with controllable damage intensity, avoiding collateral damage to surrounding organs. It is simple to operate, has high model repeatability, and can construct mouse models of chronic pancreatitis of different degrees, making it suitable for basic research on pancreatic diseases.

An assembly and / or system has a cutting device configured to cut tissue; and an inflatable device configured to be inserted into the cut tissue to further separate the cut tissue. The inflatable device may be wedge-shaped to separate the cut tissue upon insertion into an incision. The inflatable device is inflatable and otherwise adjustable to separate the tissue to a medically indicated degree. For example, the inflatable device can move axially relative to the cutting device; and / or can be inserted into or removed from the sheathing canal to adjust the exposed inflation length thereof; and / or may include two or more individually inflatable elements. The inflatable device can thus achieve blunt tissue dissection after making an initial incision into the tissue with a sharper instrument.

A tissue dissection device and method thereof, the tissue dissection device is connectable to a needle used to define a puncture path. The tissue dissection device includes a blade (170) that cuts the skin while inserting the device into the puncture path to enlarge the puncture path. The tissue dissection device may be configured to laterally separate from an elongated medical device (50) (e.g., a guidewire). The tissue dissection device may include a channel (131) for receiving the elongated medical device. The channel may be configured to (i) retain the elongated medical device within the channel in the absence of intentional manipulation by a clinician and (ii) facilitate lateral removal of the elongated medical device from the channel in response to intentional manipulation. A needle assembly includes a needle coupled to the tissue dissection device. The tissue dissection device may include a sheath (121) extending along a distal portion of the tissue dissection device.

A laparoscopic instrument includes fluid carrying channels incorporated into lateral aspects of jaws of the instrument and extending to outlets adjacent distal tips of the jaws, fluid carrying channels incorporated into a shaft of the instrument, and flexible fluid carrying channels connecting the distal ends of the shaft channels with the proximal end of respective jaw channels. An actuator on the device handle controls either delivery of fluid jets emanating lateral to tissue grasped between the instrument jaws or suction from the distal tips of the jaws to remove fluid in the vicinity of the jaws. The fluid jets perform atraumatic tissue dissection lateral to the structures grasped by the jaws, while the grasping jaws provide counter traction while conducting soft tissue hydro-dissection, by stabilizing the tissue in a direction opposite to the force exerted by the hydro-dissection fluid jets.

A surgical instrument comprises first and second jaws movable relative to each other between open and closed positions, a cutting electrode with a cutting surface for tissue dissection and at least one sealing electrode for sealing or coagulating tissue. The cutting electrode includes one or more insulation layers for securing the cutting electrode to one of the jaws and for protecting the jaws from the heat and energy generated at the cutting surface during operation. An actuator mechanism is coupled to the first and second jaws for moving the jaws between the open and closed positions. At least one portion of the actuator mechanism comprises a conductive pathway for electrically coupling the cutting and / or sealing electrode(s) to a source of energy. Thus, the mechanical components of the actuator mechanism include electrically conductive pathways to reduce the number of conductors extending through the device, thereby providing a more compact and maneuverable instrument.

An ablation system includes an ablation generator, catheter, and a closed-loop ablation processor operably coupled thereto. The processor receives baseline tissue properties, such as baseline tissue impedance, tissue thickness, tissue anatomical location, tissue type, catheter-tissue contact force, catheter stability against the tissue, and baseline electrogram signal morphology. The processor also receives waveform parameters for the generator. Using the baseline tissue properties and the waveform parameters, the processor determines whether pulsed field or radiofrequency ablation therapy should be delivered and computes corresponding target ablation metric(s), such as a target ablation index. The processor then commands the generator to deliver ablation therapy to the tissue and monitors lesion formation using intra-therapeutic tissue properties (and waveform parameters) to compute intra-therapeutic ablation metric(s) and comparing the intra-therapeutic ablation metric(s) to the target ablation metric(s). Ablation therapy ceases when the intra-therapeutic ablation metric(s) satisfy the target ablation metric(s).

In one aspect, the invention relates to a method of quality control in an image registration process, the result of which is used in an automated anatomical process of anatomy of tissue from an anatomical slide on which tissue slices cut from a tissue sample are placed. The method (10) comprises the steps of: obtaining (11) a first image of a reference slide comprising a reference sample cut from the same tissue sample; obtaining (12) a second image of the anatomical slide; registering (20) the first image onto the second image wherein the transformation matrix is calculated as part of the image registration process to produce a best fit between the first image and the second image; calculating (30) a first quality metric for the image registration process based on a degree of overlap between the first image and the second image; calculating (40) a second quality metric for the image registration process based on parameters indicative of skewness and asymmetric scaling of the transformation matrix; comparing (50) each value of the calculated first and second quality metrics with a corresponding threshold to determine if each quality metric is satisfied; if the first or second quality metric is not satisfied, it is determined that the image registration quality is unsatisfactory, and the determination is reported (60) to the user.

An ablation system includes an ablation generator, catheter, and a closed-loop ablation processor operably coupled thereto. The processor receives baseline tissue properties, such as baseline tissue impedance, tissue thickness, tissue anatomical location, tissue type, catheter-tissue contact force, catheter stability against the tissue, and baseline electrogram signal morphology. The processor also receives waveform parameters for the generator. Using the baseline tissue properties and the waveform parameters, the processor determines whether pulsed field or radiofrequency ablation therapy should be delivered and computes corresponding target ablation metric(s), such as a target ablation index. The processor then commands the generator to deliver ablation therapy to the tissue and monitors lesion formation using intra-therapeutic tissue properties (and waveform parameters) to compute intra-therapeutic ablation metric(s) and comparing the intra-therapeutic ablation metric(s) to the target ablation metric(s). Ablation therapy ceases when the intra-therapeutic ablation metric(s) satisfy the target ablation metric(s).