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119 results about "Damages skin" patented technology

Burn and damaged skin recovery degree evaluation method based on skin image recognition

The invention discloses a burn and damaged skin recovery degree evaluation method based on skin image recognition, and the method comprises the steps: obtaining a visible light image and an infrared thermal imaging image of a skin burn patient, carrying out the preprocessing, and fusing into a skin burn image; performing feature extraction, recognition and segmentation to obtain a burn area image; constructing a static feature set based on the burn feature parameters, constructing a three-dimensional model of the burn wound based on the burn area image and the depth image, and constructing a dynamic feature set; and inputting the extracted static and dynamic features into the optimized deep learning-support vector machine fusion model for training, carrying out final classification on a recovery stage, and calculating the time required for complete healing. The method provided by the invention not only can effectively capture the static feature information of the burn area, but also can dynamically monitor the recovery change trend of the wound in real time, accurately predict the time required for complete healing, and can significantly improve the accuracy and personalized assistance of burn diagnosis and treatment.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Oil-control acne-removal composition and application thereof

The invention relates to the field of cosmetics, in particular to an oil-controlling and acne-removing composition and application thereof. The black tea fermentation liquor, the olive leaf extract and the silybum marianum extract are compounded and have a synergistic effect after being combined, a stronger oil control network is formed, and the oil control effect is greatly improved compared with that when a single component is used; a multi-channel and multi-target acne removal path is formed, and the acne removal effect is multi-dimensionally improved compared with that when a single component is used; the skin barrier function can be further enhanced, the water loss is reduced, and the acne skin damaged skin can be recovered more quickly. The black tea fermentation liquor, the olive leaf extract and the silybum marianum extract are all natural plant extracts, are high in safety and are suitable for sensitive skin. After the three components are compounded, the safety is high, the oil-controlling and acne-removing effects of the oil-controlling and acne-removing composition are remarkably improved through the synergistic effect, and the acne problem can be more comprehensively solved.
Owner:GUANGZHOU ZHONGZHUANG BEAUTY COSMETICS CO LTD +1

Repair composition based on mussel mucin and application of repair composition in skin barrier repair

The invention relates to the technical field of repair compositions, and discloses a repair composition based on mussel mucin and application of the repair composition in skin barrier repair. The invention discloses a mussel mucoprotein-zinc composite microcapsule repair agent, which is prepared from the following components in parts by weight: mussel mucoprotein-zinc composite microcapsules, modified carboxymethyl chitosan, isolactone palmitate, a pH response type ceramide slow release system, dimeticone, cetostearyl alcohol, a calcium ion activating agent, an auxiliary repair factor, beheneth-25, caprylic / capric triglyceride, glyceryl monostearate, glyceryl distearate, pentanediol and citric acid. The preparation method comprises the following steps: adding ethanol, phenoxyethanol / ethylhexylglycerin, trehalose, beta-glucan and purified water; according to the whole technical scheme, through functional complementation and process optimization of all the components, synergistic interaction is achieved, the transpedermis water loss amount can be rapidly reduced, the water content of the skin cuticle is increased, the damaged skin barrier structure can be repaired from the source, and the resistance and stability of the skin are remarkably improved.
Owner:HEFEI SHELL PARTY INNOVATIONS TECH CO LTD

Liquid crystal bionic water-locking and oxygen-permeating nursing composition as well as preparation method and application thereof

The invention provides a liquid crystal bionic water-locking and oxygen-permeating nursing composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The skin care product is prepared from components in percentage by weight as follows: 20%-40% of glycerin, 5%-10% of hydrogenated lecithin, 5%-10% of phytosterols, 0.1%-0.5% of sodium stearoyl glutamate, 0.01%-0.05% of sodium methyl stearoyl taurate, 0.1%-1% of ceramide NP, 1%-10% of caprylic / capric triglyceride, 1%-10% of squalane, 0.1%-1% of tocopheryl acetate, 0.01%-0.3% of DNA sodium, 0.001%-0.1% of fibronectin and the balance of water. 0.001-0.1% of soluble collagen and the balance of water. The liquid crystal bionic water-locking and oxygen-permeating nursing composition provided by the invention can better form a breathable protective film on the surface of skin, reduce water loss of the skin and help to repair a damaged skin barrier, so that the water-locking and oxygen-permeating nursing effect is achieved.
Owner:GUANGDONG ZAIMETIAN BIOTECHNOLOGY CO LTD

Composition for repairing skin barrier as well as preparation method and application thereof

The invention provides a composition for repairing a skin barrier as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The invention discloses a composition for repairing a skin barrier. The composition comprises ceramide NP1, ceramide AP, ceramide EOP, asiaticoside and DNA sodium. The composition is used for repairing skin from related proteins such as endogenous and endogenous injury, inflammatory factor inhibition, light injury, skin cuticle barrier and the like, and can deeply resist inflammation, relieve and maintain stability in an endogenous and endogenous two-way manner, and repair the damaged skin barrier in a multi-level and multi-dimensional manner, so that the skin problems such as skin dryness, roughness, desquamation, redness and swelling, pruritus and the like are improved.
Owner:SICHUAN LIYAN WORKSHOP BIOTECHNOLOGY CO LTD

Treatment gun clamping device and treatment gun

The utility model provides a treatment gun clamping device and a treatment gun, the treatment gun clamping device comprises a gun seat assembly and a clamping seat assembly, the gun seat assembly comprises two clamping blocks, one end points of the two clamping blocks are hinged with each other, the other end points of the two clamping blocks are connected with each other through a connecting piece to form a hoop, and the clamping seat assembly is connected with the gun seat assembly. The gun seat assembly is used for clamping a treatment gun and externally connecting an auxiliary device, the gun seat assembly is detachably connected with the clamping seat assembly, and the clamping seat assembly supports the treatment gun through the gun seat assembly. The treatment gun can be placed through the gun base assembly, the situation that in the treatment process, medical staff need to hold the treatment gun for a long time, so that arms are sour and fatigued is avoided, the labor intensity of doctors is reduced, the ultrasonic treatment effect is improved, and meanwhile the different treatment requirements that the skin of a patient is not damaged or damaged can be met.
Owner:CHONGQING HAIFU (HIFU) TECHNOLOGY CO LTD

Medical bacterial cellulose dressing with high water retention capacity and preparation method and application thereof

The application provides a medical bacterial cellulose dressing with high water retention capacity and a preparation method and application thereof, and belongs to the technical field of medical supplies. The medical bacterial cellulose dressing with high water retention capacity is prepared by reacting a bacterial cellulose membrane with a sodium hyaluronate solution in the presence of tetramethylphosphonium chloride, and the water retention time of the dressing is not less than 2000 min. The prepared medical bacterial cellulose dressing with high water retention capacity has great advantages in actual medical application. For burn and scald patients, traditional dressings are often difficult to keep the wound moist for a long time, and if they are removed after drying, secondary wound damage will be caused. However, the dressing can provide a persistent and stable moist environment for the wound and accelerate the repair and regeneration of damaged skin cells due to its excellent water retention capacity.
Owner:HUNAN DEPUS MEDICAL TECH CO LTD

Multifunctional biomaterial with photoprotection and repair functions and preparation method and application thereof

The application discloses a multifunctional biomaterial with light protection and repair functions, which comprises the following components in percentage by mass: 4-8% of methacrylated gelatin, 0.5-2% of nanomicelles of ferulic acid, 0.5-1% of adhesive peptides, 0.5-1.5% of hyaluronic acid and 0.5-1% of ekdromicin. The application further discloses a preparation method of the multifunctional biomaterial and application thereof. The multifunctional biomaterial realizes a trinity synergistic effect of 'protection-repair-regeneration', target enrichment of active ingredients to damaged parts, and can stimulate vascular regeneration, improve skin microcirculation, has antioxidant, anti-inflammatory and healing functions, and promotes repair of light-damaged skin.
Owner:GUANGDONG ADAPTIVE BIOTECHNOLOGY CO LTD

A water-soluble, breathable, skin protective film composition, and methods of making and using the same

The application provides a water-soluble breathable skin protection film composition and a preparation method and application thereof, relates to the technical field of skin care products and functional coating, and the water-soluble breathable skin protection film composition contains the following components in percentage of total weight: (a) 5-30% of a film-forming polymer component, the film-forming polymer component is a combination of polyvinylpyrrolidone / vinyl acetate copolymer and partially alcoholized polyvinyl alcohol; (b) 5-25% of C2-C4 lower alcohol and / or C2-C10 aliphatic diol; (c) 0.01-10% of a polyether-modified silicone surfactant; (d) 0.01-18% of a functional auxiliary agent; (e) the balance is water. The composition can form a breathable film with a water vapor transmission rate greater than 500 g / (m 2 ·24h) on the skin, which can be removed within 90 seconds by using 25-30 DEG C normal temperature water. When used in medical treatment, the composition does not contain lower alcohol and has no irritation to damaged skin.
Owner:KONGJIA TECHNOLOGY (FOSHAN) CO LTD

Children skin soothing and repairing cream containing egg yolk oil extract and preparation method of children skin soothing and repairing cream

The invention relates to the technical field of child skin care products, in particular to a child skin soothing and repairing cream containing egg yolk oil extract and a preparation method of the child skin soothing and repairing cream. The prepared children skin soothing and repairing cream is long in acting time and high in repairing efficiency; wherein the egg yolk oil hydrogel beads are easy to break at the damaged skin, and the egg yolk oil emulsion is released, so that the action time can be prolonged, the egg yolk oil emulsion is released at the damaged skin in a targeted manner, and the utilization rate and the repair efficiency are effectively improved; the silk fibroin microspheres reduce active oxygen and have good ultraviolet resistance; through the synergistic effect of the components in the plant extract, various problems of fragile skin barrier, dryness, water shortage, redness, inflammation and the like of children can be effectively solved; the auxiliary materials can promote mutual fusion of the components while playing a role in moistening and moisturizing, and compared with the prior art, the composition has a wide application prospect.
Owner:SANMU HEALTH SERVICE YUNNAN CO LTD

Whitening and Anti-aging composition, and method for preparing same, and use thereof

The present invention relates to the field of cosmetic technology, and particularly, to a whitening and anti-aging composition, a method for preparing same, and use thereof. The whitening and anti-aging composition is prepared from the following ingredients in parts by weight: 0.1-2 parts of hydroxypropyl cyclodextrin; 0.1-2 parts of tocopherol; 1-5 parts of an emulsifier; 0.5-1 part of a preservative; 1-5 parts of a functional solvent; 0.1-0.9 part of retinol; 0.1-3 parts of an adjusting mixed acid agent; and 90-100 parts of deionized water. The adjusting mixed acid agent consists of lactobionic acid, inositol hexaphosphate, and ferulic acid, and the ratio of lactobionic acid to inositol hexaphosphate to ferulic acid is (5-7):(0.5-1):1. The method for preparing the whitening and anti-aging composition comprises: dissolving the adjusting mixed acid agent in a portion of deionized water; adding hydroxypropyl cyclodextrin, the emulsifier, and retinol into the remaining deionized water and heating for dissolution; and finally, mixing and stirring the two resulting solutions along with the addition of tocopherol and the preservative during the process to give the composition. The composition exhibits excellent whitening and anti-aging effects with low irritation, and is also suitable for populations having sensitive skin with damaged skin barriers.
Owner:SHANGHAI ZUNYA IND CO LTD

Topical Chemical Composition

A topical cutaneous composition remarkably reduced eczema, psoriasis, and other skin problems in human patients. The topical cutaneous composition is formulated using natural and toxicologically harmless components as a skin cream with an acidic or a caustic property. When the topical cutaneous composition is applied to the afflisted area, the topical cutaneous composition attacks, sooths, and cures damaged skin.
Owner:SIMPLY ROOTS LLC

Ginsenoside composition gel liquid soap for double residence on skin and preparation method thereof

The invention relates to the technical field of skin care compositions, in particular to a ginsenoside composition gel soap liquid capable of doubly residing on skin. The composition does not contain a surfactant and a foaming agent, takes a panaxoside composition in a specific proportion as a core active component, and cooperates with a licorice extract, hyaluronic acid, a rapeseed extract, a bearberry leaf extract and a willow bark extract to form a stable gel system. The composition replaces traditional surfactants and foaming agents, solves the problems that traditional components damage skin barriers and cannot stay for a long time, has dual functions of deep cleaning and skin care, and has two characteristics of cleaning type non-staying products and cream type staying products at the same time. Experiments prove that the composition has excellent effects of resisting oxidation, whitening, deodorizing and removing cutin scales, is high in safety, does not contain harmful ingredients such as hormones and antibiotics, and can stay on the skin for a long time to play a continuous role.
Owner:潘东凯

Moisturizing and repairing medical spray containing glycosylglycerol and preparation method of moisturizing and repairing medical spray

The invention relates to a moisturizing and repairing medical spray containing glycosylglycerol and a preparation method of the moisturizing and repairing medical spray. The anti-inflammatory and anti-inflammatory gel is prepared from the following components: 0.5%-2% of glycosylglycerol (wherein the mass ratio of 2-beta GG to 2-alpha GG is 0.08: 1), 0.01%-0.5% of recombinant humanized III-type collagen, 0.3%-0.7% of trehalose, 0.05%-0.3% of beta-glucan (wherein the molecular weight ratio is specific), 3%-10% of a humectant, 0.1%-1% of a soothing anti-inflammatory agent, 0.01%-0.5% of a pH regulator, 0.01%-0.3% of a preservative and the balance of deionized water. Wherein the four active components meet a specific relational expression. The invention also provides a preparation method and application of the medical spray. According to the medical spray disclosed by the invention, through the specific proportion and synergistic matching of the active ingredients, excellent moisturizing performance, barrier repairing function, wound healing activity and soothing and anti-inflammatory effects are realized, and the medical spray is high in safety, good in use experience and suitable for nursing of various skin types, particularly sensitive skin and damaged skin.
Owner:青岛中科蓝智生物科技发展有限公司

Skin repair composition, skin repair product and application of skin repair composition and skin repair product

The invention provides a skin repair composition, a skin repair product and application of the skin repair composition and the skin repair product. The skin repair composition comprises the polydeoxyribonucleotide and the salt thereof, the Ectoine or the derivative thereof and the schizophyllan, overcomes the defect of single function of bioactive substances, and has the effects of inhibiting expression of inflammatory factors and accelerating repair of damaged skin pigmentation. The three active ingredients in the skin repair composition are not simply superposed, but generate a synergistic gain effect of '1 + 1 + 1gt, 3', the safety and effectiveness are obviously superior to those in the prior art, and a brand-new and excellent solution is provided for solving the problems of light and moderate acne of teenagers and hyperpigmentation after healing.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

Medicine applying device for premature infant iatrogenic skin injury

The utility model relates to the technical field of medical instruments, in particular to a medicine applying device for premature infant iatrogenic skin injury. Comprising a material guide pipe, a chassis and a disc, the bottom of the material guiding pipe is fixedly connected with a base plate, at least one through hole is formed in the base plate, the through holes are evenly distributed in the circumferential direction of the base plate, the base plate is connected with a disc in an inserted mode through the through holes, a flowing hole is formed in the middle of the disc, and the disc is communicated with the material guiding pipe through the flowing hole. Through the arrangement of the material guide pipe and the circular sponge, liquid medicine is injected into the circular sponge from the material guide pipe, the circular sponge is in contact with the skin injury position of the premature infant after being stained with the liquid medicine, and the skin injury position of the premature infant can be massaged while the liquid medicine is smeared through the circular sponge; the skin injury part of the premature infant can be massaged before liquid medicine is smeared, different nursing tools do not need to be replaced, and the medicine smearing efficiency is improved.
Owner:邢台市人民医院

A liquid crystal biomimetic water-locking and oxygen-permeable nursing composition, its preparation method and application

This invention provides a liquid crystal biomimetic water-locking and oxygen-permeable skincare composition, its preparation method, and its application, belonging to the field of cosmetic technology. It comprises the following components by weight percentage: 20-40% glycerin, 5-10% hydrogenated lecithin, 5-10% phytosterols, 0.1-0.5% sodium stearoyl glutamate, 0.01-0.05% sodium methylstearoyl taurate, 0.1-1% ceramide NP, 1-10% caprylic / capric triglyceride, 1-10% squalane, 0.1-1% tocopheryl acetate, 0.01-0.3% sodium DNA, 0.001-0.1% fibronectin, 0.001-0.1% soluble collagen, and the balance being water. The liquid crystal biomimetic water-locking and oxygen-permeable skincare composition provided by this invention can better form a breathable protective film on the skin surface, reduce skin moisture loss, and help repair damaged skin barriers, thereby achieving the effect of water-locking and oxygen-permeable skincare.
Owner:GUANGDONG ZAIMETIAN BIOTECHNOLOGY CO LTD

Pure natural bacteriostatic anti-allergic olive oil handmade soap and preparation process thereof

The handmade soap contains a lipidosome nano-emulsion compound system, has good film-forming property, can protect sensitive components, can encapsulate active components in traditional Chinese medicinal material extracts which are easy to oxidize, and can resist a strong alkaline environment of the medicated soap, so that the handmade soap has a good anti-allergy effect, and the handmade soap has a good anti-allergy effect and a good anti-allergy effect. The nano-emulsion increases fat-soluble components, improves bioavailability and promotes skin absorption, and the nano-scale particle size (100-200nm) of the liposome and the nano-emulsion can penetrate through the cuticle, so that slow-release delivery is realized, and the drug effect is prolonged. Meanwhile, an artificial moisturizing barrier can be constructed for the skin, and moisture evaporation on the surface of the skin is reduced; the traditional Chinese medicinal material extract has relatively strong bacteriostatic activity and very strong antioxidant activity on pathogenic bacteria and pathogenic fungi. Therefore, the handmade soap disclosed by the invention has the effects of moisturizing, cleaning, inhibiting bacteria, resisting inflammation, resisting allergy and the like, can better protect fragile skin, and can help wounded skin heal at the same time.
Owner:兰州海关技术中心

Liquid foundation suitable for sensitive skin and preparation method

PendingCN121588014ACosmetic preparationsMake-upPurslane extractCrocus sativus
The invention discloses liquid foundation suitable for sensitive skin and a preparation method, and belongs to the technical field of cosmetics. The invention relates to a liquid foundation suitable for sensitive skin. The liquid foundation comprises an active core component: 3-8% of an aloe barbadensis leaf extract; the base component comprises 45%-60% of A-phase raw materials, 25%-35% of B-phase raw materials and 8%-15% of C-phase raw materials; synergistic soothing and repairing components: 0.5%-1.2% of a purslane extract, 0.3%-0.8% of a crocus sativus flower extract and 0.2%-0.6% of a cardiospermum halicacabum flower and leaf extract; a low-irritation antibacterial auxiliary component: 0.01% to 0.05% of chlorhexidine digluconate; by adopting a synergistic antibacterial system of the aloe barbadensis leaf extract and the low-concentration chlorhexidine digluconate, while the dosage of a synthetic antibacterial agent is reduced, broad-spectrum efficient antibacterial is realized, and the sensitization rate of a human patch test is less than or equal to 0.1%; on the other hand, the plant-derived emulsifier is used for replacing part of the synthetic thickening agent and matched with the relieving and repairing effects of the peptide compound component, so that the overall irritation of the formula is further reduced, and the composition is further suitable for sensitive skin and barrier damaged skin to be used for a long time.
Owner:SHANGHAI DUOXUAN BIOTECHNOLOGY CO LTD

Bionic cuticle moisturizing barrier composition and preparation method thereof

The invention belongs to the field of skin care materials, and provides a bionic cuticle moisturizing barrier composition and a preparation method thereof. Sodium pyrrolidone carboxylate, an amino acid compound, bimodal molecular weight sodium hyaluronate, trehalose and betaine are used as water-phase humectants, squalane, caprylic / capric triglyceride and phytosterol oleate are used as oil-phase carriers, and cholesterol, hydrogenated lecithin, octyldodecanol and ceramide NP are used as sebum-like barrier components. A layered liquid crystal and alpha gel double-network structure is constructed through a segmented phase inversion emulsification and microjet homogenization process, and a narrow distribution system with the emulsification drop diameter D50 being 0.3-5 microns and SPAN being not larger than 1.2 is achieved. The technical problems that a high-density barrier, ventilation and refreshing are difficult to obtain at the same time, rheological unbalance of a high-solid-content system is caused, and irritation and phase structure damage are caused by traditional high-energy homogenization are solved, and the application value in sensitive skin and barrier damaged skin care is achieved.
Owner:SHANTOU QIWEI IND CO LTD

A composition with soothing sensitive skin function and its preparation method and application

The present application relates to the technical field of skin care products, and discloses a composition with the effect of soothing sensitive skin, which is composed of the following components in mass percentage: plant extract 10-12%, skin repair factor 2-3%, jasmine hydrolat 10%, humectant 6-7%, and the balance being water. The composition with the effect of soothing sensitive skin has significant soothing effect, which is close to the soothing effect of common hormone ointments on the market. The composition can significantly reduce inflammatory factors, has good anti-inflammatory effect, simultaneously repairs damaged skin, enhances the moisturizing function, and enhances the skin barrier through the moisturizing and repairing effect. The composition has the effect of resisting anaphylaxis by reducing the content of trypsin and inhibiting the allergic reaction of mast cells. Human patch test and fish embryo development toxicity test prove that the composition with the effect of soothing sensitive skin has no skin adverse reactions and no development toxicity, is mild, safe and non-irritating, and is suitable for preparing skin care products for adults and infants.
Owner:工毅设计有限公司

A multi-ceramide-containing repair composition and a method for preparing the same

This invention discloses a repair composition containing multiple ceramides and its preparation method, belonging to the field of cosmetic technology. The repair composition, by mass parts, comprises ceramide AP, ceramide EOP, ceramide NP, phytosphingosine, Centella asiatica extract, Portulaca oleracea extract, Hydrangea macrophylla extract, ectoine, and tripeptide-1. This invention utilizes multiple ceramides and phytosphingosine to biomimetically replenish the lipids of the stratum corneum, combined with the synergistic effects of various plant active ingredients and active peptides, to effectively achieve multiple effects such as skin barrier repair, soothing and anti-inflammatory properties, and anti-allergy. This invention also provides a barrier repair serum containing this repair composition and its preparation method. The serum has stable physicochemical properties and, verified by in vitro cell experiments and human efficacy tests, can rapidly repair damaged skin barriers, improve sensitive symptoms such as redness and stinging, and is gentle and non-irritating, suitable for daily skincare use by people with sensitive skin and damaged skin barriers.
Owner:ANJIEYU COSMETICS TECH CO LTD +1

Plant extract composition for repairing sensitive skin and preparation method thereof

The invention belongs to the technical field of cosmetic preparation, and particularly relates to a plant extract composition for repairing sensitive skin and a preparation method of the plant extract composition. The chamomile extract, the purslane extract, the scutellaria baicalensis extract, the centella asiatica extract, the calendula extract, the salvia miltiorrhiza root extract and the witch hazel extract are specifically combined, and the raw materials can inhibit release of inflammatory factors and exert a higher anti-inflammatory effect; meanwhile, the natural active ingredients in the extract can fundamentally regulate the inflammatory response of the skin and enhance the elasticity and compactness of the skin, so that the damaged skin structure is favorably repaired, and the overall health state of the skin is improved; in addition, the composition is extracted from plants, is mild and does not cause additional stimulation to sensitive skin. Therefore, the plant extract composition provided by the invention not only has a good repairing effect, but also is green and safe.
Owner:科奕美(广州)健康产业有限公司

Use of polymer dots for treating skin

Local tissue defects, liquefaction, infection, and necrosis of skin resulted from various reasons may lead to skin damage and vascular regeneration disorders. Wound hypoperfusion, metabolic disorders, and delayed epithelial cell formation disrupt the process of normal wound healing, thereby leading to the formation of chronic ulcer. To solve the aforementioned problems, a use of polymer dot is provided. The polymer dot may be used for manufacture of a component for the treatment of skin to a subject in need, in order to restore skin damage of the subject, minimize a scar on the damaged skin of the subject, and enhance recovery of the skin of the subject after cosmetic or dermatologic surgery. The polymer dot includes a carbon dot.
Owner:CHINA MEDICAL UNIVERSITY(TW)

Skin injury organ model and method for screening drugs by using same

The invention relates to a skin injury organ model and a method for screening drugs by using the skin injury organ model, and the skin injury organ model is characterized in that skin cells, accessory structures, nerve cells, fat cells and the like form structures similar to actual skin by using an air-liquid interface skin organ preparation technology; and the damaged skin is prepared by irradiating the skin-like organ with ultraviolet rays which actually reach the ground surface. In the present invention, the skin barrier is damaged and the activity of a matrix proteolytic enzyme is improved to promote the decomposition of collagen while increasing the secretion of pro-inflammatory cytokines by irradiating with solar-simulated ultraviolet light comprising 94.5% ultraviolet light (UV-A) and 5.5% ultraviolet light (UV-B), thereby well simulating the characteristics of skin injury caused by ultraviolet light. Therefore, the invention can be used as a model of skin injury and photoaging caused by ultraviolet rays, and can be useful in potential therapeutic drug screening.
Owner:KANGSTEM BIOTECH

Polymer composition, soft tissue filler and preparation method and application thereof

The invention discloses a polymer composition, a soft tissue filler and a preparation method and application thereof, and belongs to the technical field of biomedical materials. The polymer composition comprises a biomacromolecule and a bioresponsive polymer, and the biomacromolecule and the bioresponsive polymer can form physical entanglement in the presence of active oxygen. As an effective component of the soft tissue filling agent, the polymer composition not only can significantly prolong the metabolism time and achieve a lasting filling effect, but also can endow the following properties: the process of network entanglement and tissue filling repair can be visually tracked; rOS generated in the aged skin can be removed for a long time, and the anti-inflammatory, anti-oxidation and anti-aging effects are achieved; long-term retention in skin tissues can be realized; the generation of collagen in tissues can be effectively promoted; water can be effectively locked and moisturized, and the dry state of the skin is improved; the skin repairing agent can repair damaged skin tissues and promote skin cell regeneration, and has good biocompatibility and biodegradability, and degradation products are non-toxic.
Owner:SICHUAN UNIV

An injectable wound dressing with antibacterial and near-infrared response and a preparation method thereof

The application discloses an injectable wound dressing with antibacterial and near-infrared response and a preparation method thereof, and belongs to the biomedical field.The wound dressing is made of components including the following raw materials: dendritic macromolecules, a biomacromolecule solution, a trivalent iron ion solution and a crosslinking agent solution.The wound dressing can be quickly prepared by mixing the biomacromolecule solution, the trivalent iron ion solution, the dendritic macromolecules and EDC / NHS to generate metal chelation and amide reaction, and has antibacterial and near-infrared response;the wound dressing is in a liquid state before gelation, has injectability and good adhesion, and can completely adhere to damaged skin to realize the function of protecting the skin;the wound dressing also has the advantages of high biocompatibility, simple preparation method, easy availability of raw materials and easy scale production.
Owner:TSINGHUA SHENZHEN INTERNATIONAL GRADUATE SCHOOL +1

Solid depilatory wax and preparation method thereof

The present invention discloses a solid depilatory wax and a preparation method thereof, relating to the technical field of depilatory wax. The solid depilatory wax comprises the following raw material components by mass fraction: 30-70% natural resin, 5-20% fatty alcohol, 3-20% natural wax, 2-10% tackifier, 0.2-5% natural plant oil, 0.2-5% anti-inflammatory, soothing and repairing agent, 0.2-3% skin conditioner, 0.2-3% antioxidant, and 0.2-2% stabilizer; wherein the tackifier is selected from at least one of polyisobutylene, hydrogenated polydicyclopentadiene, hydrogenated (styrene / methylstyrene / indene) copolymer, and hydrogenated (styrene / butadiene) copolymer; and the anti-inflammatory, soothing and repairing agent comprises component A and component B, wherein component A is guaiacyl ether, and component B is peppermint oil, purslane extract, golden chamomile extract, houttuynia cordata extract, and scutellaria baicalensis extract. The depilatory wax provided by the present invention has a low melting point and a good depilatory effect, and can improve the damaged skin barrier function caused by hair plucking, thereby preventing skin or skin follicle inflammation caused by hair removal.
Owner:深圳市汇尚科科技有限公司

Skin care composition for eczema based on sebum film bionics as well as preparation method and application of skin care composition

The invention discloses a skin care composition for eczema based on sebum membrane bionics as well as a preparation method and application of the skin care composition for eczema based on sebum membrane bionics, the skin care composition for eczema based on sebum membrane bionics comprises active ingredients such as rosa palmifolia fruit oil, oat kernel oil, ceramide, phytosterol oleate, simmondsia chinensis seed oil and squalane, the mass ratio of the rumex mairei fruit oil to the oat kernel oil to the ceramide to the phytosterol oleate to the simmondsia chinensis seed oil to the squalane is (0.005 to 5) to (0.02 to 20) to (0.001 to 5) to (0.001 to 20) to (0.01 to 15) to (0.01 to 15). By implementing the method, the lipid composition structure of a human body sebum film can be accurately simulated, the damaged skin barrier can be effectively repaired, the anti-inflammatory soothing characteristic is achieved, multiple protection is provided for the special pathological state of eczema skin, and the method can be widely applied to the field of cosmetics.
Owner:GUANGDONG DEMA HEALTH PROD CO LTD