86results about How to "Avoid bacterial infection" patented technology

The invention provides a method of treating degenerative disc disease and discogenic pain by disposing a hydrogel tissue sealant within the intervertebral disc, where the hydrogel fills voids and tears in the annulus fibrosus and replaces leaked material from the nucleus pulposus. The hydrogel is formed in situ from a substantially liquid premix, which can be emplaced with a syringe needle or a catheter into the intervertebral disc, where it forms the hydrogel by gelation. The hydrogel can also include a therapeutic or a protective material, or a radiopaque or MRI-active agent to aid in visualization.

A genetically modified bacteriophage is disclosed which comprises:

• • (i) an exogenous polynucleotide which encodes an agent which reduces the toxicity of a bacterium; and
  • (ii) an exogenous polynucleotide which encodes a selectable marker.

Uses thereof and kits comprising same are also disclosed.

This invention relates to the field of antimicrobial agents and more specifically it relates to Efflux Pump Inhibitor (EPI) compounds to be co-administered with antimicrobial agents for the treatment of infections caused by drug resistant pathogens. The EPI compounds are soft drugs which exhibit a reduced propensity for tissue accumulation. The invention includes novel compounds useful as efflux pump inhibitors, compositions and devices comprising such efflux pump inhibitors, and therapeutic use of such compounds.

The invention relates to devices (1) for draining or closing a natural or artificial bladder outlet by means of a balloon body (3) made of preferably micro-scale thin-walled Polyurethane, which has a vesical anchor, is transurethrally sealing and is extended into the urethra or through the urethra. According to the invention, the balloon body is seated on a shaft body (2) supporting the balloon, and the filling of the balloon body is preferably done with air.

A cochlear implant electrode includes an electrode carrier having an electrode array with a groove disposed in a longitudinal direction along the electrode carrier, and a stopper positioned around the electrode carrier. The stopper has a protrusion on its inner surface that is configured to be positioned within the groove such that the stopper is movable with respect to the electrode carrier.

The invention discloses a hair tonic appliance and health products, which is characterized by the following: constituting with nitrogen agent and acid agent; choosing the nitrogen from sodium nitrite (sodium nitrite density at 0. 02%-2. 0%) or plant extract of concentrated enriched nitrite; choosing the acid agent from organic acid or inorganic acid; combining the nitrogen agent and the acid agent; discharging effective element nitric oxide; diastolizing capillary blood of brain with nitric oxide; accelerating blood circulation; increasing local blood providing quantity and oxygen delivery. This invention can reach ideal germinal effect.

The invention relates to the technical field of educational toys, and particularly discloses a robot with a sterilizing device. The robot with the sterilizing device comprises a robot cavity and a motor, wherein a sterilizing device is arranged in the robot cavity and comprises a disinfectant storage chamber; a motor is rotatably connected with a stirring column; the stirring column is provided with stirring blades and a cam; a piston cylinder is arranged on the right side of the cam; a piston and a piston rod is arranged in the piston cylinder; the other end of the piston rod is attached to the outline of the cam; the piston cylinder is further provided with a one-way air inlet valve and a one-way air outlet valve; the one-way air outlet valve is connected with an air bag; a box body is arranged on the outside of the air bag; an automatic valve is arranged at an outlet of the air bag; a control mechanism for the automatic valve is arranged on the inner wall of the box body; the automatic valve is connected with a venturi tube; a throat portion of the venturi tube communicates with the disinfectant storage chamber through a suction tube; and an outlet of the venturi tube is connected with a sprayer through a pipe. The invention aims to solve the problem that bacteria on the surface of the robot can infect a user.

The invention discloses a preparation method of an amur grape beibinghong dry red wine. The method comprises the steps of preparing grape mash by artificially threshing and crushing raw materials; adding potassium metabisulfite; adjusting the sugar content of the grape mash by adding sugar; performing first fermentation by adding active dry yeast; separating skins and dregs to obtain a supernatant liquor; performing second fermentation on the supernatant liquor; separating wine lees to obtain a raw wine; performing tank turning and ageing; rapidly cooling the raw wine by adding a clarification stabilizer, and freezing; filtering and sterilizing; bottling; storing. The preparation method is scientific, reasonable and easy to control operations, and can be applied to special wine manors for producing high-grade dry red wines in a small scale.

A hair implant includes at least two strands including at least one of mammalian hair and synthetic hair; and an anchor, which: (a) includes silicone, (b) is configured for subcutaneous implantation, (c) includes a fracture line configured to facilitate fracturing of the anchor along the fracture line for ease of removal of the implant after subcutaneous implantation, and (d) is configured to provide a scaffold for collagen growth after subcutaneous implantation, wherein at least one of the at least two strands is joined to the anchor on one side of the fracture line and at least one of the at least two strands is joined to the anchor on an opposite side of the fracture line such that each fragment formed by fracturing the implant includes at least one of the at least two strands. Looped implants, a hair restoration method and an implant manufacturing method are also disclosed.

Disclosed herein is the crystalline form of the potassium salt of 2-((3R,6S)-2-hydroxy-3-(2-(thiophen-2-yl)acetamido)-1,2-oxaborinan-6-yl)acetic acid. The crystalline form maybe formulated for treating subjects with bacterial infection. Accordingly, some embodiments relate to compositions and methods of administering the potassium salt of 2-((3R,6S)-2-hydroxy-3-(2-(thiophen-2-yl)acetamido)-1,2-oxaborinan-6-yl)acetic acid.

The present invention provides a method for mineralizing commercially available guided bone regeneration membranes. The method comprises the steps of (a) providing a commercially available guided bone regeneration membrane, (b) applying a mineralizing solution, and (c) microwaving the membrane. The method may further comprise (d) rinsing the membrane in a solution such as distilled water and (e) drying the membrane. The mineralizing solution may be a solution capable of supplying or delivering a mineral such as calcium or zinc. The invention further provides guided bone regeneration membranes made by the methods described. The guided bone regeneration membrane comprises a mineral, such as, for instance calcium or zinc at a weight percent of at least 5%, at least 10%, at least 12%, at least 15%, at least 18%, at least 20% or at least 25% (weight percent) of the membrane. Further, the invention provides methods for enhancing bone regeneration and methods for inhibiting bacterial infection and inflammation.

The invention discloses a traditional Chinese medicine residue fermented feed for livestock and poultry and a preparation method of the traditional Chinese medicine residue fermented feed. The traditional Chinese medicine residue fermented feed comprises the following raw materials in parts by weight of 58-62 parts of gypsum decoction residues, 10-13 parts of rhizoma anemarrhenae decoction residues, 14-16 parts of radix trichosanthis decoction residues, 10-12 parts of fructus gardeniae decoction residues, 27-31 parts of reed rhizome decoction residues, 10-12 parts of lophatherum herb decoctionresidues, 7-9 parts of pale butterflybush flower decoction residues, 12-15 parts of semen celosiae decoction residues, 13-16 parts of common selfheal fruit-spike decoction residues, 11-13 parts of pipewort decoction residues, 15-17 parts of semen cassiae decoction residues, 9-11 parts of radix scutellariae decoction residues, 3-6 parts of rhizoma coptidis decoction residues, 10-13 parts of cortexphellodendri decoction residues, 5-7 parts of radix gentianae decoction residues, 8-10 parts of radix sophorae flavescentis decoction residues, 28-32 parts of radix rehmanniae decoction residues andthe like. According to the traditional Chinese medicine residue fermented feed disclosed by the invention, various wasted traditional Chinese medicine decoction residues are sufficiently utilized, sothat effects of clearing heat and removing toxicity can be achieved for the livestock and the poultry, environmental pollution caused by the traditional Chinese medicine decoction residues is effectively avoided, a large amount of labor cost is reduced, the production cost is low, and the traditional Chinese medicine residue fermented feed is quite environmentally-friendly.

The present disclosure uses different kinds of surface treatment processes on titanium-made dental implants. The growth and attachment conditions of bone cells (MC3T3-E), fibroblasts(NIH 3T3) and epidermal cells (XB-2) on the metal surface of titanium slices with different surface treatments are observed. Tetra-calcium phosphate is used to perform secondary sand-blasting process to clean up the metal surface and provide calcium ions for osteoblastoma physiology. Thus, by adjusting the cells adhesive and proliferative abilities, the success rate of the clinical applications in dental implant is improved.

Disclosed herein are Efflux Pump Inhibitor (EPI) compounds that can be co-administered with antimicrobial agents for the treatment of infections caused by drug resistant pathogens. The EPI compounds are soft drugs which exhibit a reduced propensity for tissue accumulation. It is demonstrated that the EPIs can be used to increase the potency, decrease bacterial resistance and development of bacterial resistance, and increase killing effectivness of tigecycline. Also disclosed are methods of treatment and pharmaceutical compositions for co-administering tigecylcine with an EPI.

The invention provides a novel efficient fire and burn injuries plaster agent and its preparation method, it achieves the purpose of the treatment of burns using the action of nitrogen agent storing drug layer(4) prepared by nitrite and acid agent storing drug layer(2) prepared by reductant.Pharmacological experiments confirmed that the new efficient fire and burn injuries plaster agent based nitric oxide in the invention can treat 1 and 2 degree fire and burn injuries and accelerate skin healing.

RNAIII inhibiting peptide (RIP) has been established as an effective inhibitor of staphylococcal infections. Non-peptide small molecule analogs based on a pharmacophore conforming to the putative atomic structure of RIP, can be identified by computer screening of that pharmacophore against established libraries of known small molecules other than peptides. One such identified structural analog is hamamelitannin. When tested for effective inhibition of staphylococcal infections, hamamelitannin demonstrated inhibition similar to that exhibited by RIP. Other analogs can be identified and similarly used.

A method of treating or preventing a bacterial infection in an animal comprises administering to the animal an effective amount of an antibacterial peptide, the antibacterial peptide being derived from degraded date pits which are degraded by solid state degradation by a fungus, Trichoderma reesei. The antibacterial peptide has a molecular mass of less than 10 kDa and an amino acid sequence including (a) SEQ ID NO:4 or (b) SEQ ID NO:6. The bacterial infection is caused by a Gram-positive bacteria or a Gram-negative bacteria, for example, a Salmonella species, a Campylobacter species, a Shigella species, an Escherichia species, a Pseudomonas species, and a Staphylococcus species.

The invention discloses a long-hair rabbit feed capable of reducing the death rate in a young rabbit period. The feed is prepared from the following raw materials in parts by weight: 50-150 parts of corn flour, 1-50 parts of bean meal, 1-50 parts of bagasse, 1-50 parts of wheat bran, 1-10 parts of carrot powder, 1-10 parts of pine needle powder, 0.5-3 parts of bone meal, 0.5-3 parts of fish meal, 0.5-3 parts of spirulina, 0.1-5 parts of a Chinese herbal medicine additive, 0.1-2 parts of a nutrition additive and 0.1-1 part of a microelement additive. Long-hair rabbits are raised by the feed, so that the appetite can be enhanced; the immunity and the disease resistance are improved; and the death rate of the long-hair young rabbits is effectively reduced.

The present invention provides methods and compositions for treating or preventing bacterial infections, where a pharmaceutically acceptable iron chelator that reduces biological availability of iron for one or more strains of bacteria, such as VK28 or an analog or derivative thereof is administered to a patient in need of treatment. The method also provides methods and compositions where an iron chelator and an antibiotic are administered to a patient in need of treatment for a bacterial infection.

A hair implant suitable for subcutaneous implantation is provided having an anchor comprising an anchor body, and at least one collagen receiving structure selected from the group consisting of at least one tunnel disposed through the anchor body and an external surface feature of the anchor body. The anchor further comprises at least one hair strand projecting from a distal end of the anchor body, wherein the at least one collagen receiving structure is configured to support collagen ligature growth after subcutaneous implantation of the hair implant so as to anchor the anchor to a hair implant recipient, and the collagen receiving structure is free of hair. A fracture line in the anchor body allows the body to fragment, thereby releasing collagen ligatures and allowing the implant fragments to “release” and fall out of the skin. The at least one hair strand may comprise a primary hair element with emerging hair elements.

The invention relates to hemorrhoid ointment, belonging to the technical field of traditional Chinese medicines. The hemorrhoid ointment is prepared from the following raw materials in parts by weight: 50-80 parts of dendrobium huoshanense, 30-45 parts of borneol, 20-30 parts of honeysuckle flowers, 20-30 parts of camphor, 15-25 parts of dandelions, 10-20 parts of rhizoma picrorhizae, 10-20 parts of radix angelicae, 4-8 parts of vinegar and 90-150 parts of vaseline. The hemorrhoid ointment has a high effect taking speed, has the effects of clearing away heat and toxic materials and preventing bacterial infection, inflammation and fester, has a wide range of treatment, and has good curative effects on internal hemorrhoids, external hemorrhoids and mixed hemorrhoids. The hemorrhoid ointment which adopts pure plant medicines does not have side effects on human bodies, is low in cost and simple in use, and greatly relieves the pain of patients.