20 results about "Pentanone" patented technology

This invention discloses a method for producing 4-methyl-2-pentanone, which is implemented using a 4-methyl-2-pentanone production apparatus. The apparatus includes a reactive distillation column, a condenser connected to the top of the reactive distillation column, and a reboiler connected to the bottom of the column. The reactive distillation column has a rectification section, a reaction section, and a stripping section arranged sequentially from top to bottom. During operation, a catalyst is placed in the reaction section, and 4-methyl-2-pentanol is introduced into the reaction section. The temperature of the reaction section is controlled at 180–280°C. The gas phase produced by the reaction is condensed by the condenser to produce 4-methyl-2-pentanone. This production method features high conversion rate, stable product quality, and low energy consumption.

This invention relates to "an efficient and safe method for synthesizing perfluoropentanone," belonging to the field of organic chemical synthesis. The method for synthesizing perfluoropentanone is characterized by the following steps: under the action of hexafluoropropylene CF2=CF-CF3, fluorophosgene CF2O, and trifluorobromomethane CF3Br, perfluoropentanone (C5F) is generated in the gas phase. 10 O. The raw materials of this invention are inexpensive and readily available; the product separation and purification are simple; it is easy to industrialize; and it produces less industrial waste.

The application belongs to the technical field of organic chemical synthesis and heterogeneous catalysis, and particularly relates to a catalyst for preparing 2,4-dimethyl-3-pentanone from isobutyric acid or isobutyric anhydride and a preparation method thereof. The application overcomes key technical bottlenecks in the existing gas-phase ketonization reaction, such as serious cracking side reactions, quick deactivation of the catalyst due to carbon deposition, and low selectivity of the target product. The application provides a method for efficiently preparing 2,4-dimethyl-3-pentanone from isobutyric acid or isobutyric anhydride. The method innovatively constructs a modified HZSM-5 molecular sieve catalyst with a micropore-mesopore multi-level pore structure, and introduces specific metal oxide active components to construct acid-base synergistic active centers, thereby realizing directional regulation of the reaction path. The method not only significantly inhibits the competitive monomolecular cracking reaction, greatly improves the selectivity of the bimolecular coupling ketonization reaction for generating 2,4-dimethyl-3-pentanone, but also effectively eliminates the diffusion resistance of macromolecular products by using mesoporous channels, thereby fundamentally solving the problem of easy carbon deposition and deactivation of the catalyst, and having excellent industrial application prospects and technical progress.

This invention belongs to the field of ketoxime synthesis technology and provides a method for synthesizing 3-pentanone oxime. The method uses 3-pentanone, hydrogen peroxide, and ammonia as raw materials, adds a catalyst, and reacts in a closed system. After the reaction, the mixture is filtered and distilled under reduced pressure to obtain 3-pentanone oxime. The catalyst is a fluorine-modified Ti-MOR molecular sieve, obtained by reacting the Ti-MOR molecular sieve with an NH4F-alcohol solution. The method provided by this invention features high yield, high purity, and low waste, with a single-pass yield ≥96% and purity ≥99.0%. The catalyst can be recycled up to 6 times without significant activity decline. The entire process involves no organic solvent discharge and low salt content in the wastewater, meeting the requirements of green production.

The application discloses a kind of metal organic framework UiO-66 modified terahertz super surface detection lung cancer marker 2-pentanone method.The method is based on a kind of terahertz multi-resonance super surface sensor, and its unit structure is composed of two S-shaped open resonant ring and an antenna, produces three independent resonant valleys.To improve detection selectivity and structural stability, the application is functionalized to super surface using three-layer modification strategy: APTES is introduced in sequence to form stable interface layer, spin-coated amino-rich PEI layer is provided with additional adsorption sites to interact with ketone molecules, and finally spin-coated metal organic framework UiO-66 is used as sensing layer to realize effective pre-enrichment of 2-pentanone.During detection, three resonant valleys show linear red shift with the increase of 2-pentanone concentration, and the lowest test concentration is 20 ppm.The application uses multi-resonance characteristics combined with multi-dimensional response mode to realize rapid, high-sensitivity and high-selectivity non-contact detection of lung cancer marker 2-pentanone.

This invention relates to the field of chemical synthesis technology, specifically a method for preparing 2,3,3,5-tetramethylindole. The method comprises using p-methylphenylhydrazine hydrochloride and 3-pentanone as raw materials, generating 2,3,3,5-tetramethylindole through a one-step condensation-cyclization reaction in acetic acid medium, followed by further processing steps. This synthetic method offers significant advantages: First, it is highly efficient, with a one-step condensation-cyclization reaction, a molar yield of 60-68%, HPLC endpoint control, and a total processing time of one day, making it suitable for industrial production. Second, it operates under mild conditions, using acetic acid as both solvent and catalyst, with a reaction temperature of 112℃, allowing the use of ordinary enamel-lined reactors and avoiding corrosion from traditional strong acid equipment. Third, it achieves excellent purity, with no isomers and a purity exceeding 99%, offering flexible purification at low cost. Fourth, it is more environmentally friendly, with a dichloromethane recovery rate ≥90%, and wastewater with a near-neutral pH for easy treatment. Fifth, it is easily scaled up, with quantitative formulas for parameters and flexible process adjustments, adaptable to various production fields.

This invention discloses a method for producing 4-hydroxy-2-pentanone from acetone and acetaldehyde, belonging to the field of fine chemical intermediate synthesis technology. The method uses bio-based acetone and bio-based acetaldehyde as raw materials, and 1,8-diazabicyclo[5.4.0]undec-7-ene as a catalyst. In a DBU-H₂O catalytic system, high-purity 4-hydroxy-2-pentanone is obtained through a cross-aldol condensation reaction followed by separation and purification. This invention solves the technical problems of low product yield, numerous by-products, dark product color, strong odor, and difficulty in catalyst recovery in existing technologies by optimizing reaction parameters and selecting specific catalysts. The reaction conditions are mild, the operation is simple, and the energy consumption is low. The catalyst can be recycled, and all raw materials are bio-based, meeting the requirements of green chemical development. It is suitable for large-scale industrial production, and the product can be widely used in bakelite preparation, flavorings, pharmaceutical intermediates, and other fields.

This invention discloses a method for preparing 1,2-pentanediol, comprising using 2-pentanone as a substrate, adding 2-keto reductase, linalool dehydratase, formate dehydrogenase, lysozyme, coenzyme NAD+, and water to react and obtain n-pentene. The obtained n-pentene is then thoroughly mixed with ethanol. This mixture is then fed into a reaction system containing olefin monooxygenase, epoxide hydrolase, formate dehydrogenase, lysozyme, coenzyme NAD+, MgSO4, and water using a fed-batch method. After the n-pentene and ethanol mixture has been completely added, the reaction continues for a period of time, followed by extraction to obtain 1,2-pentanediol. This preparation method uses 2-pentanone as a raw material, catalyzing the synthesis of 2-pentanol via 2-keto reductase. 2-pentanol is then catalyzed by a dehydrating enzyme to generate n-pentene, which is then catalyzed by an olefin monooxygenase to generate 1,2-epoxypentane. Finally, epoxide hydrolase ring-opens the 1,2-pentanediol. This process requires only four enzymatic catalytic reactions for efficient synthesis.

This invention discloses a method for synthesizing 2-pentylcyclopentenone and the catalyst used. The method uses 2-pentylcyclopentenone and hydrogen as raw materials, and performs a hydroisomerization reaction in the presence of a catalyst to obtain 2-pentylcyclopentenone. The catalyst is a supported catalyst and includes a support, an active metal, a rare earth metal oxide, and a modifier. The active metal and rare earth metal oxide are supported on the support. The support includes zinc aluminate with a spinel structure. The modifier contains phosphorus and / or nitrogen. This synthesis method achieves high conversion of 2-pentylcyclopentenone, high selectivity and high purity of the target product 2-pentylcyclopentenone, and the process is relatively simple, suitable for industrial production. The catalyst exhibits high catalytic activity and high stability.

The application provides a method for determining ultra-low content thallium in iron ore, which adopts an extraction separation method to extract thallium from a multi-component test solution containing iron, calcium, aluminum and silicon, realizes separation and enrichment, and then determines by using an inductively coupled plasma emission spectrometer; the application utilizes the chemical properties of thallium and alkane compounds containing active oxygen substituents represented by 4-methyl-2-pentanone, adopts an extraction method for separation and enrichment, establishes a suitable analysis method, and completes the detection of ultra-low content thallium in ore.

The application relates to the technical field of synthesis of organic silicon materials, and particularly discloses a safe and efficient pentanone oxime silane and a preparation method thereof. The preparation method of the safe and efficient pentanone oxime silane comprises the following steps: dissolving 2-pentanone oxime in a first organic solvent to obtain a first solution; dissolving vinyl trihalosilane in a second organic solvent to obtain a second solution; under the conditions of stirring and 20-35 DEG C, the second solution is added dropwise into the first solution, after the dropwise addition is completed, the reaction is continuously carried out until completion, and a reaction liquid is obtained; the reaction liquid is cooled to room temperature, filtration is carried out, the filtrate is collected, and concentration drying is carried out, so that 2-pentanone oxime silane is obtained. The application can improve the boiling point of 2-pentanone oxime silane, the viscosity of the 2-pentanone oxime silane is moderate, the 2-pentanone oxime silane has good processing performance, and the application range is wide.

The present invention provides a method for synthesizing 5-hydroxy-4,6-dimethylbenzocyclopentanone, which relates to the field of organic chemical synthesis technology and includes a two-step reaction. Specifically, using 2-methoxy-1,3-dimethylbenzene as a starting material, it first reacts with 3-chloropropionyl chloride to obtain 4-methoxy-3,5-dimethyl-1-(3-chloropropionyl)benzene. Then, the 4-methoxy-3,5-dimethyl-1-(3-chloropropionyl)benzene undergoes intramolecular cyclization and demethylation to obtain 5-hydroxy-4,6-dimethylbenzocyclopentanone. The synthetic route of the present invention is short and feasible, the starting materials and excipients are inexpensive and readily available, the reaction is highly reactive, the operation is simple and easy to control, and the yield of the target product is high.

The present application relates to a kind of methods for synthesizing corresponding alcohol by electrocatalytic hydrogenation of carbonyl compound, using flow electrolytic cell or split H-type electrolytic cell, adding carbonyl compound in cathode electrolyte, collecting liquid phase alcohol product at reaction output end.The carbonyl compound includes formaldehyde, acetaldehyde, acetone, n-propyl aldehyde, n-butyl aldehyde, n-pentanal, 4-hydroxy-2-butanone, diacetone alcohol, 2-pentanone, cyclobutanone, furfural and other carbonyl-containing compounds.Different types of electrolytic cell are used, and the iron-based electrocatalyst constructed has the characteristics of low cost, high activity and high selectivity.Compared with traditional thermal catalytic technology, the electrocatalytic hydrogenation of carbonyl compound to synthesize corresponding alcohol technology is carried out at room temperature and normal pressure, using water as hydrogen source, which not only reduces energy consumption and production cost, but also is green, safe and efficient, in line with the requirements of green chemical industry.

The application provides a continuous separation system and process for a glycerol-glycerol carbonate mixture, which comprises an extraction column, an extract phase extractant recovery rectifying column and a raffinate phase extractant recovery rectifying column; a first inlet, a second inlet and a third inlet are respectively arranged at the bottom, the top and the middle of the extraction column, the third inlet of the extraction column is used for receiving the glycerol-glycerol carbonate mixture, the first inlet of the extraction column is used for receiving a first extractant, and the second inlet of the extraction column is used for receiving a second extractant; the first extractant is methyl isobutyl ketone, cyclohexanone or 2-pentanone, and the second extractant is water; the top outlet of the extraction column is connected with the feed inlet of the extract phase extractant recovery rectifying column, and the bottom outlet is connected with the feed inlet of the raffinate phase extractant recovery rectifying column. The system and the process thereof have a simple separation process, a wide applicable concentration range and can realize efficient separation of the glycerol-glycerol carbonate mixture.

The negative pressure tower ethanol purification system comprises a negative pressure tower, a rectifying tower, a reflux tank and a vacuum unit, one end of a gas phase outlet pipe at the top of the negative pressure tower is connected with the rectifying tower, one end of a gas phase outlet pipe at the top of the rectifying tower is connected with a condenser through a condensation pipe, and one end of a discharge pipe of the condenser is connected with the reflux tank; one end of the return tank discharging pipe is connected with a finished product collecting tank. Under the action of negative pressure, an ethanol material mixed with isopropanol and 2-pentanone is introduced into the negative pressure tower, the isopropanol and ethanol are gasified and enter the rectifying tower for rectification, the 2-pentanone flows downwards and is discharged through the first liquid phase discharge pipe, the ethanol is gasified and is condensed through the condenser and then enters the reflux tank, and the isopropanol flows downwards and is discharged through the second liquid phase discharge pipe. In a negative pressure environment, light components and heavy components can be more quickly enriched towards the tower top or the tower bottom, the separation time is shortened, meanwhile, the system pressure is reduced, the boiling point of materials can be obviously reduced, and heat required by separation can be reduced. And through cooperation of the negative pressure tower and the rectifying tower, the ethanol purification effect and efficiency can be improved.

The application discloses a method for continuously synthesizing terpinolene. The method uses citral and amine R-NH2 as initial raw materials to perform a reaction to obtain a citral imine compound, which is subjected to a cyclization reaction under the catalysis of an acidic cation resin to obtain a cyclization product; the cyclization product and water are subjected to a hydrolysis reaction in a water-miscible organic solvent to obtain a cyclic citral; the cyclic citral is subjected to a condensation reaction with 2-pentanone, and finally subjected to a hydrogenation reaction to obtain terpinolene; and each step is continuously reacted in a continuous reaction device. The synthesis method can significantly reduce the degree of side reactions in each synthesis step, improve the selectivity and yield of the target product, and can realize continuous production and is suitable for industrial production.

This invention discloses a method and apparatus for producing high-purity 6PPD from crude antioxidant 6PPD. The method includes: using crude antioxidant 6PPD as raw material, separating light component impurities through thin-film evaporation to obtain high-purity 6PPD antioxidant; simultaneously, the separated light components are collected by condensation, and the solvent is recovered. The apparatus includes a falling film evaporator, a material transfer pump, a rotary thin-film evaporator, a vacuum trap, a gas-liquid separator, a Roots screw vacuum unit, and a condenser. The antioxidant 6PPD product obtained by this invention through thin-film evaporation has stable quality and a purity ≥98.5%, and the separated light components, such as 4-methyl-2-pentanone and 4-methyl-2-pentanol, can be recycled, improving economic efficiency while meeting environmental protection requirements.