The invention discloses a composition and a soft capsule for treating cold for night use. The composition comprises acetaminophen, dextromethorphan hydrobromide, succinic acid doxylamine, polyethylene glycol, polyhydric alcohols and povidone; the soft capsule comprises a soft capsule shell and content in the soft capsule shell, wherein the content comprises acetaminophen, dextromethorphan hydrobromide, succinic acid doxylamine, polyethylene glycol, polyhydric alcohols and povidone, and the soft capsule shell comprises the following components: gelatin, plasticizer, purified water and colorant. Aiming at overcoming the defects of the prior art, the invention provides the composition for treating cold for night use, and the composition has simple components and is stable and effective. The invention also aims at providing the soft capsule comprising the composition, and the soft capsule is applicable to relieving cold symptoms such as headache, fever, cough, rhinobyon, rhinorrhea, irritability, and the like.