33 results about "2-Acetylpyridine" patented technology

The invention discloses a method for synthesizing doxylamine succinate. 2-acetylpyridine is taken as an initiative material, and the method comprises the following steps of: reacting the 2-acetylpyridine with a Grignard reagent prepared from bromobenzene and magnesium to obtain 2-pyridyl phenyl methyl carbinol; reacting the 2-pyridyl phenyl methyl carbinol with sodium amide and 2-dimethylaminoethyl chloride in turn to obtain doxylamine; and performing salt-forming reaction on the doxylamine and succinic acid to obtain the doxylamine succinate. The synthesis route is orientation reaction without byproduct. The doxylamine succinate is an ethanol antihistamine, and has antihistaminic and cholinolytic effects and obvious tranquillizing effect.

The invention discloses salted egg yolk essence which is composed of caprylic capric glyceride, dimethyl sulfide, 3-hydroxy-2-butanone, dimethyl disulfide, 1-octylene-3-alcohol, furfural, 5-methyl furfural, 3-methylthiopropanal, 2-acetylpyridine, 3-methyl methylthiopropionate, 2-acetylthiazole, methyl(2-methyl-3-furyl)disulfide, isovaleric acid, 2, 4-decadiene aldehyde, ethyl maltol, 3-methylthiopropanol, caprylic acid, 2, 4-dimethyl-5-acetylthiazole, heliotropin, vanillin, capric acid, 2-pentylfuran, isovaleraldehyde, furanone and 2-acetylpyrazine. The salted egg yolk essence is authentic andfull in fragrance, low in cost, good in fragrance lasting and penetrating in fragrance, has the advantage of being delicious, fragrant and oily and can serve as a food additive to be applied in producing food like bake and beverages.

The invention provides an organic white light material o-pyridine p-benzene bis(imino) cadmium/mercury complex and a preparation method thereof, relates to an organic light-emitting material and a preparation method therefore, and aims at solving the problems of the conventional white light-emitting material that the synthesis process is complex, the yield is low and the service life of fluorescence is short. The organic white light material consists of an o-pyridine p-benzene bis(imino) cadmium complex [N, N'-bis(2-acetylpyridine methylene) benzene-1, 4-diamine] CdCl2 and an o-pyridine p-benzene bis(imino) mercury complex [N, N'-bis(2-acetylpyridine methylene) benzene-1, 4-diamine] HgCl2. The preparation method comprises the following steps of: 1, dissolving N, N'-bis(2-acetylpyridine methylene) benzene-1, 4-diamine and CdCl2 or HgCl2 into methanol, and heating and refluxing; 2, filtering turbid reaction liquid and collecting solid powder; and 3, washing with methanol to obtain the organic white light material. The preparation method is simple in synthetic process, the yield can be up to more than 60%, and the service life of fluorescence is relatively long.

The invention discloses a probe and a preparation method and application thereof. The preparation method includes mixing and stirring 4-bromobenzaldehyde, 2-acetylpyridine, 4-vinyl pyridine, brominated alkanes, ammonium hydroxide, palladium acetate, triphenyl phasphine, triethylamine and DMF (dimethylformamide) prior to reflux, stirring for 1 hour at a room temperature to obtain a precipitate, filtering and recrystallizing in acetic acid so as to obtain a reactant; taking the reactant out, cooling the reactant to the room temperature to generate a precipitate, filtering to obtain a solid and drying the solid so as to obtain the probe. The probe is capable of quantitatively analyzing Zn<2+> concentration in a solution and has the advantages of low quantitative analysis concentration, high anti-interference capability, simplicity in operation, visual results and simplicity and convenience in analysis.

The invention belongs to the technical field of cigarette filter production and in particular relates to Chinese yam flavor essence for cigarette popping beads and application of the essence in cigarettes. The Chinese yam flavor essence is composed of Chinese yam extract, 2,3,5-trimethyl pyrazine, vanillin, 2-acetylpyridine, ethyl maltol, bitter almond oil and caprylic capric triglyceride. The Chinese yam flavor cigarette popping beads can be prepared by utilizing the essence, and the popping beads can be added into cigarette filters and can be applied to preparing the cigarette popping beads. By providing specific Chinese yam flavor essence for cigarette popping beads and combining with a perfect popping bead production process, the cigarette popping bead products with stable and uniform forming quality can be prepared. After the popping beads are arranged in the cigarette filters, irritation of the cigarettes can be well weakened, flavor of the cigarettes is improved and enriched, and the flavor enrichment, sensory quality and smoking interestingness of the cigarettes can be obviously improved. Therefore, the Chinese yam flavor essence has high application value and popularization and application significances on design, development, production and sales of the cigarette popping beads.

The invention discloses a preparation method of 2-acetylpyridine. The preparation method comprises the following steps: (1) with 2-picolinic acid as a raw material, adding a first inert solvent and acatalyst, stirring and heating to 55-65 DEG C, dropwise adding a chlorinating agent, heating until a reflux reaction is occured, and performing reduced pressure distillation to obtain 2-pyridinecarbonyl chloride; (2) adding an inorganic salt catalyst, a second inert solvent, an alkaline substance and dialkyl malonate in a reaction bottle, sufficiently stirring, dropwise adding the 2-pyridinecarbonyl chloride, performing a heating reaction, neutralizing with hydrochloric acid, separating out an organic layer, washing with saturated sodium bicarbonate and a saturated salt solution in sequence, drying, and performing vacuum concentration to obtain 2-pyridinecarbonyl Di-tert-Butyl malonate; and (3) adding the 2-pyridinecarbonyl Di-tert-Butyl malonate in a mixed solution of water, organic acidand inorganic acid to perform a reflux reaction, regulating to be neutral with alkaline liquid, extracting with an organic solvent, and performing vacuum concentration to obtain 2-acetylpyridine. Thepreparation method has the advantages of being simple in raw materials, simple in operation, mild in condition, high in yield and small in pollution.

The invention discloses an indium complex taking APT as a ligand and having a potential leaving group as well as a synthesis method and application of the indium complex. The synthesis method comprises the following steps: dissolving 2-acetylpyridine in a mixed solution of methanol and acetonitrile, adding aminothiourea, uniformly mixing the mixture, dropwise adding acetic acid, uniformly mixing the mixture, refluxing the mixed solution, performing vacuum concentration to obtain a concentrate, extracting the concentrate with ethyl acetate, washing a product with saturated sodium bicarbonate and water in order after the extraction step, and carrying out silica gel column chromatography separation to obtain a ligand; adding the ligand obtained in the step 1) and INCl3 into a closed reactionkettle, dropwise adding a mixed solution of methanol and ethanol for dissolving, sealing the reaction kettle after dissolving, and standing the reaction kettle in a vacuum drying oven at 65-80 DEG C for 72 hours to obtain the indium complex. The complex shows good inhibition activity on a cisplatin drug-resistant strain, new data is provided for application of the novel metal-based complex to drug-resistant tumor cell strains, and the synthesis method is simple to operate and convenient to implement.

The invention relates to a novel rapeseed oil flavor enhancer and an application method thereof in preparation of a concentrated-fragrance rapeseed oil, and belongs to the field of edible oil processing technology. The invention discloses the rapeseed oil flavor enhancer. With 2,5-dimethylpyrazine, hydroxyl acetone, 2-methylpyrazine, isovaleraldehyde, hexaldehyde, 2,3,5-trimethylpyrazine, furfuryl alcohol, 2-methyl-5-ethylpyrazine, 1-methyl-4-cyclohexene, 2-heptenal, 2-methylbutyraldehyde, 2-acetylthiophene, 3-phenyl furan, 2-acetylpyrrole and 2-acetylpyridine as raw materials, the rapeseed oil flavor enhancer is formed through mixing, stirring and canning. The concentrated-fragrance rapeseed oil is prepared by directly adding the novel rapeseed oil flavor enhancer into a rapeseed oil.

The present invention relates to a corn essence for food and a preparation method thereof. The corn essence is prepared from the following raw materials: vanillin, ethyl maltol, 2-acetyl pyrazine, dimethyl sulfide, 2-acetyl thiazole, 2-acetylpyridine, tetrahydroquinoxaline, 4-methyl-5-hydroxyethylthiazole, butanedione, and propylene glycol. The corn essence has rich corn aroma, and is mellow in flavor and long in fragrance lasting.

The invention relates to a method for producing propylene epoxide through propylene epoxidation reaction, which mainly solves the problem that methods for catalyzing epoxidation of styrene by adopting a molybdenum Schiff alkali compound are undisclosed in the previous literatures. According to the method, tert-butyl hydroperoxide and propylene are taken as raw materials and are in contact with a catalyst for 1-12 hours to generate propylene epoxide in the presence of a solvent under the conditions that the reaction temperature is 40-120 DEG C, the reaction pressure is 0.5-5 Mpa and the molar ratio of the tert-butyl hydroperoxide to the propylene is 1:(1-10), wherein the catalyst is a 2-acetylpyridine isonicotinic acid hydrazide molybdenum complex, the chemical structural formula of the 2-acetylpyridine isonicotinic acid hydrazide molybdenum complex is shown in the specification, and the technical scheme that R1 is selected from -OHR2 or R2 is CnH2n+1, and n is 2-10 better solves the problem. The method can be applied to the industrial production of propylene epoxide prepared through propylene epoxidation reaction.

The invention relates to a 2-acetylpyridine benzoyl hydrazine molybdenum complex and a preparation method thereof, mainly solving the problem that a molybdenum Schiff alkali coordination compound is undisclosed in previous patents. The technical scheme of the invention is adopted to solve the problem, and in the technical scheme, the chemical structural formula of the 2-acetylpyridine benzoyl hydrazine molybdenum complex is shown in the specification, wherein R1 is selected from -OHR2 or R2 is CnH2n+1, and n is 2-10. The preparation method can be applied to the industrial production of the 2-acetylpyridine benzoyl hydrazine molybdenum complex.