22 results about "Hexaldehyde" patented technology

The invention relates to a method for preparing an at least partially acetal-protected sugar, involving the step of reacting a sugar or a sugar derivative selected from the group consisting of valeraldoses, hexanoses, valeraldoglycosides and hexanoglycosides with an aldehyde or a source of aldehyde in the presence of a heterogeneous acidic catalyst, forming an at least partially acetal-protected sugar selected from the group consisting of compounds of formulae (I), (II), (III), (IV), (V), (VI,) (VII), (VIII), (IX), (X), (XI) and (XII), # imgabs0, r1, R1 ', R2, R2', R3, R3 ', R4, R5, R6, R7, R8, R9, R10, R11, R12 and R12' are Y or Z-E, where R1 and R1 ', R2 and R2', R3 and R3 ', R12 and R12' are equal to or different from each other and Y is hydrogen or a linear, branched or cyclic hydrocarbon moiety having 1 to 20 carbon atoms, Z is a linear, branched or cyclic hydrocarbon moiety having 0 to 12 carbon atoms, optionally substituted with 1 to 4 C1 to C4 alkyl groups, 1 to 4 halogen atoms or benzyl groups, e is-COOH,-CH (COOH) 2,-COOR19,-CH (COOR20) (COOR21),-CHO,-CH (CHO) 2,-C2H3, CH (C2H3) 2,-CHCHR22,-CHCR23R24,-C2H,-C2R25,-N3,-NH2,-CH (NH2) 2,-NHR26,-CH (NHR27) (NHR28),-NR29R30,-CH (NR36OH),-OH,-OR35,-CH (R36OH), and R19, R20, R21, R22, R23, R24, R25, R26, R27, R28, R29, R32, R33, R34 and R37OH and R13, R14, R15, R16, R17 and R18 are each independently hydrogen or a linear, branched or cyclic hydrocarbon moiety having 1 to 20 carbon atoms.

The application provides a black fungus provenance characteristic molecular marker and application thereof, and the molecular marker comprises the following: the molecular marker 2-acetyl furan, beta-pinene and 2-pinene of Shaanxi black fungus; the molecular marker 2-propanol and 2, 6-dimethyl pyrazine of Heilongjiang black fungus; the molecular marker pentanal and 2-butanone of Jilin black fungus; the molecular marker n-hexanal and acetic acid of Zhejiang black fungus; and the molecular marker 2-methyl propionaldehyde and hexanoic acid of Fujian black fungus. The molecular marker can be used for identifying the provenance of black fungus. The application first provides the provenance characteristic molecular marker of black fungus, the molecular marker can replace all chemical components of black fungus and serve as a detection basis of the provenance of black fungus; compared with existing black fungus physical and chemical indexes and artificial sensory recognition analysis, the provenance characteristic molecular marker of black fungus provided by the application improves the accuracy and recognition rate of detection, and provides a simple, rapid and effective scheme for provenance identification of black fungus.

A process for making an acrylate selected from n-butyl acrylate and 2-ethylhexyl acrylate includes subjecting a feedstock comprising ethanol of a renewable source to dehydration to produce an ethylene stream of a renewable source. Mutually converting the ethylene stream of renewable source with olefins to obtain propylene of renewable source; the interconversion of olefins comprises dimerization of ethylene to obtain n-butene; and obtaining propylene according to (i) a metathesis reaction between the obtained n-butenes and ethylene. Subjecting the propylene of renewable origin to a series of chemical conversions including alpha), beta), delta) and epsilon) or alpha), gamma), delta) and epsilon) to obtain an acrylate selected from n-butyl acrylate and 2-ethylhexyl acrylate: alpha) hydroformylation of the propylene to produce n-butyraldehyde; beta) a hydrogenation reaction of the n-butyraldehyde obtained in alpha) to produce n-butanol; gamma) condensation of the n-butyraldehyde obtained in alpha) to produce 2-ethyl-3-hydroxyhexanal, and subjecting the 2-ethyl-3-hydroxyhexanal to a hydrogenation reaction to produce 2-ethylhexanol; delta) an oxidation reaction of the propylene to produce acrylic acid; epsilon) the esterification reaction of the acrylic acid with one of the n-butanol obtained in beta) or the 2-ethylhexanol obtained in gamma) to produce an acrylate. The process provides a reaction scheme for n-butyl acrylate and 2-ethylhexyl acrylate of renewable sources.

The present invention relates to a process for preparing an at least partially acetal-protected sugar, comprising the step of reacting a sugar or sugar derivative selected from the group consisting of aldopentoses, aldohexoses, aldopentosides and aldohexosides with an aldehyde or aldehyde source in the presence of a heterogeneous acidic catalyst to form an at least partially acetal-protected sugar selected from the group consisting of compounds of formula (I), (II), (III), (IV), (V), (VI), (VII), (VIII), (IX), (X), (XI) and (XII): In the formula, R1, R1', R2, R2', R3, R3', R4, R5, R6, R7, R8, R9, R 10 , R 11 , R 12 and R 12 and R and R′, R and R′, R and R′, and R 12 and R 12 are identical or different from one another; and Y is hydrogen or a straight, branched, or cyclic hydrocarbon moiety having 1 to 20 carbon atoms; Z is a linear, branched, or cyclic hydrocarbon moiety having 0 to 12 carbon atoms, optionally substituted with 1 to 4 C1-C4 alkyl groups, or 1 to 4 halogen atoms, or a benzyl group; and E is -COOH, -CH(COOH)2, -COOR 19 , -CH(COOR 20 )(COOR 21 ), -CHO, -CH(CHO)2, -C2H3, -CH(C2H3)2, -CHCHR 22 , -CHCR 23 R 24 , -C2H, -C2R 25 , -N3, -NH2, -CH(NH2)2, -NHR 26 , -CH(NHR 27 )(NHR 28 ), -NR 29 R 30 , -CH(NR 31 R 32 )(NR 33 R 34 ), -OH, -OR35 , or -CH(R 36 OH)(R 37 OH); and R 19 , R 20 , R 21 , R 22 , R 23 , R 24 , R 25 , R 26 , R 27 , R 28 , R 29 , R 30 , R 31 , R 32 , R 33 , R 34 and R 35 are C1 to C 20 is alkyl; and R 20 and R 21 , R 23 and R 24 , R 27 and R 28 , R 29 and R 30 , R 31 and R 32 , and R 33 and R 34 are identical to or different from one another; and R 36 and R 37 are, independently of one another, absent or straight-chain or branched C1-C 12 is a hydrocarbon chain; and R 13 , R 14 , R 15 , R 16 , R 17 and R 18 are each independently hydrogen or a straight-chain, branched-chain, or cyclic hydrocarbon moiety having 1 to 20 carbon atoms. JPEG2025536078000039.jpg83102

The invention discloses a preparation method of trans-2-hexenal. The preparation method comprises the step of enabling n-hexanal to react in the presence of a palladium catalyst, a bipyridine ligand and an oxidizing agent to obtain the trans-2-hexenal. According to the method, the trans-2-hexenal is prepared through the selective oxidative dehydrogenation reaction of the n-hexanal in the presence of the palladium catalyst, the bipyridine ligand and the oxidizing agent, the reaction yield and selectivity are greatly improved, the content of cis-configuration byproducts can be controlled to be 1% or below, and the rectification purification difficulty of the trans-2-hexenal is greatly reduced.

A 1,3-diol monoesters of formula (la): (Ia) Wherein each R' is independently C1-10 alkyl; one Ra group is hydrogen and the other Ra group is –C(O)CH(R)2; each R is independently C1-10 alkyl; or two R groups on the same carbon atom are taken together to form a cyclic group selected from heteroaryl, heterocycloalkyl, cycloalkyl and aryl, each of which is optionally substituted; and wherein the compound comprises at least one cyclic group as defined above. Compounds wherein all R and R’ may be C1-10 alkyl are also disclosed. Use of the compounds as coalescence agents in coating compositions is also disclosed. Processes for preparing the compounds are disclosed, such processes being based upon the Aldol-Tishchenko reaction. Compositions comprising the compounds, along with methods of coating a substrate using the compositions, and substrates coated with the compositions are also disclosed. The cyclic group is preferably a heterocyclic group, particularly furan or tetrahydrofuran. The compounds may in particular be the Aldol-Tishchenko product of furfural and 2-ethybutyraldehyde or 2-ethylhexanal; or 2-ethylhexanal and 2-ethylbutyraldehde. [See Formula Ia of Claim 1 a filed]

Process for the preparation of acetal-protected sugars comprising the step of reacting a diol group of a sugar selected from the group consisting of valeralose and hexaldehyde with one or both compounds of formula (Ia) and / or formula (Ib) in the presence of a homogeneous or heterogeneous catalyst, to form an acetal protected sugar selected from the group consisting of compounds of formula (II), formula (III) and formula (IV); wherein R1 and / or R2 are each independently-Z-X, and wherein Z is a linear, branched or cyclic hydrocarbon moiety having 1 to 10 carbon atoms, optionally substituted by 1 to 4 C1-C4 alkyl groups or 1 to 4 halogen atoms, or Z is-B-D, where B is a linear hydrocarbon moiety having 1 to 3 carbon atoms and may be present or absent, D is an aromatic moiety having 6 carbon atoms, wherein Z may be present or absent, and X is-COOH,-CH (COOH) 2,-COOR3, CHO,-C2H3,-C2H,-CHOR4OR5,-N3,-NHR6,-NR7R8,-F,-Cl,-Br,-I, or, if Z is present, X is-OH, NH2, or-SH, optionally substituted by 1 to 4 C1-C4 alkyl groups, 1 to 2-OH groups, 1 to 2-OCH3 groups, or 1 to 4 halogen atoms, and wherein Z may be present or absent,-COOR3, CHO,-C2H3,-C2H,-CHOR4OR5,-N3,-NHR6,-NR7R8,-F,-Cl,-Br,-I; r3, R4 and R5 are independently selected from the group consisting of linear, branched or cyclic hydrocarbon moieties having 1 to 20 carbon atoms and optionally substituted by 1 to 4 C1 to C4 alkyl groups and / or 1 to 4 halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; r6 is a C1-C4 alkyl group; r7, R8 and R9 are each independently a C1-C4 alkyl group; r30 and R31 are each independently selected from the group consisting of hydrogen and a linear or branched hydrocarbon moiety having 1 to 4 carbon atoms, with the proviso that R30 and R31 cannot be hydrogen at the same time; r < 10 > is selected from the group consisting of-H,-OH,-CH2OH,-OR13 or-CH2OR14; r < 11 > and R < 12 > are independently selected from the group consisting of-OH or-OR13; r13 and R14 are independently selected from hydrocarbon moieties having from 1 to 10 carbon atoms; and n and p are each independently 0 or 1.

The present invention discloses the screening of exhaled breath markers for early diagnosis of lung cancer using HPPI-TOFMS and their applications. The present invention provides the application of 16 volatile organic compounds as exhaled breath biomarkers for lung cancer in the development of products for diagnosing or assisting in the diagnosis of lung cancer. The 16 volatile organic compounds are: acetaldehyde, 2-hydroxyacetaldehyde, isoprene, valeraldehyde, butyric acid, toluene, 2,5-dimethylfuran, cyclohexanone, hexanal, heptanal, acetophenone, propylcyclohexane, octanal, nonanal, decanal and 2,2-dimethyldecane. The inventors of the present invention identified 16 exhaled breath biomarkers for lung cancer by performing perioperative exhaled omics testing using HPPI-TOFMS. The combination of these 16 exhaled breath biomarkers can distinguish between lung cancer patients and healthy people, and can be used in clinical practice to optimize lung cancer screening programs.

The present invention relates to a process for the preparation of 2-isopentyl-2- isopropyl-1,3-dimethoxypropane, said process comprising the steps of: i) contacting iso-valeraldehyde with an aqueous solution of a hydroxide base selected from the group consisting of sodium hydroxide (NaOH), potassium hydroxide (KOH) or a combination thereof, said solution having an amount of said hydroxide base of at least 20% w / v, and (m) ethanol; form (2Z)-2-isopropyl-5-methyl-2-hexenal; step ii) contacting (2Z)-2-iso-propyl-5-methyl-2-hexenal with a reducing system to form 2-isopropyl-5-methylhexanal; step iii) contacting 2-isopropyl-5-methylhexanal with formaldehyde and an inorganic base to form 2-isopentyl-2-isopropylpropane-1,3-diol; and step iv) contacting 2-isopentyl-2-isopropylpropane-1,3-diol with a methylation agent and a base to form 2-isopentyl-2-isopropyl-1,3-dimethoxypropane.

The invention belongs to the technical field of fine chemical engineering, and particularly relates to a synthesis method of cis-6-nonene-1-ol. The preparation method comprises the following steps: enabling 1, 6-hexanediol to react with tert-butyldimethylsilyl chloride, so as to obtain 6-((tert-butyldimethylsilyl) oxy) hex-1-alcohol; and adding an oxidizing agent into the 6-((tert-butyldimethylsilyl) oxy) hexane-1-alcohol to obtain the 6-((tert-butyldimethylsilyl) oxy) hexanal. And adding triphenyl (propylidene)-phosphorus into the 6-((tert-butyldimethylsilyl) oxy) hexanal to obtain the (Z)-tert-butyldimethyl (6-alkene-1-oxy) silane. The preparation method comprises the following steps: adding triphenyl (propylidene)-phosphorus into the 6-((tert-butyldimethylsilyl) oxy) hexanal; tetrabutylammonium fluoride is added into the (Z)-tert-butyl dimethyl (6-ene-1-oxy) silane, and the cis-6-nonene-1-ol is obtained. The synthetic route is mild in reaction condition, low in cost and suitable for industrial production, and the total yield can reach 29%. And secondly, the synthetic route does not generate harmful substances or dangerous compounds, and is environment-friendly.

The invention provides a comprehensive utilization method of m-pentadiene, and relates to the technical field of resource utilization, and the method comprises the following steps: S1, carrying out selective hydrogenation on m-pentadiene as a raw material under the action of a catalyst to generate n-pentene and 2-pentene; s2, the pentene prepared in the step S1 and synthesis gas are subjected to a carbonyl synthesis reaction under the action of a rhodium catalyst and a carrier to generate n-hexanal and iso-hexanal, the n-hexanal and the iso-hexanal are mixed and then hydrogenated, and n-hexanol and iso-hexanol are prepared; and S3, carrying out carbon-carbon double bond nucleophilic addition on n-hexanal and iso-hexanal prepared in the step S2 under the action of a basic catalyst, then carrying out deprotonation on hydroxyl to generate dodecenal, and finally carrying out hydrogenation on the generated dodecenal to prepare the isododecanol. The invention provides a new method for comprehensively utilizing the m-pentadiene, which not only opens up a new production line for comprehensively utilizing the m-pentadiene, but also utilizes the m-pentadiene as a raw material to produce different new material chemicals with high added values, thereby greatly enhancing the utilization value of the m-pentadiene.

The invention discloses a deodorizing method of a regenerated polypropylene material. According to the deodorizing method of the regenerated polypropylene material, supercritical CO2 extraction treatment is carried out on the regenerated polypropylene material by adopting an extracting agent, wherein the extracting agent comprises supercritical CO2 and a cosolvent; wherein the volatile odor substance of the regenerated polypropylene material comprises one or more of isoparaffin with 10 to 20 carbon atoms, isoolefin with 10 to 20 carbon atoms, decane, n-dodecane, n-tetradecane, octanal, hexanal, limonene, isoterpinene, octanone and terpene alcohol. The odor removal method can effectively remove volatile odor substances in the regenerated polypropylene material, and the odor grade of the obtained regenerated polypropylene material can meet the application requirements of automotive interiors.

The invention provides a hexamethylene(meth)acrylate composition suitable for producing a cured product with excellent physical properties, and a resin composition curable by active energy beams, and a cured product utilizing the same. The composition according to the present invention relates to a hexamethylene(meth)acrylate composition containing hexamethylene(meth)acrylate, in which the total content of a compound having two or more secondary hydroxyl groups in one molecule (A1) and a (meth)acrylate compound (A2) of compound (A1) is 100 ppm by mass or less, and the total content of 6-hydroxyhexanal and a derivative thereof (B1) and a (meth)acrylate compound (B2) of compound (B1) is 1,500 ppm by mass or less.

The application discloses a kind of Ni modified micropore-mesopore type molecular sieve and its preparation method and application, which comprises the following steps: a. in alkaline environment and normal temperature, silicon source, aluminum source, micropore directing agent, nickel source are mixed in water, after stirring, microporous molecular sieve precursor is prepared by crystallization;B. mesoporous directing agent is added to microporous molecular sieve precursor at normal temperature, after being fully stirred, micropore-mesopore type molecular sieve is obtained by crystallization, filtration, washing, calcination.The application proposes a kind of Ni modified micropore-mesopore type molecular sieve, the molecular sieve is applied to the reaction rectification of 2-ethylhexene aldehyde hydrogenation reaction liquid, can decompose acetal type heavy component, improve the yield of product 2-ethylhexanal, and kettle bottom product is rich in 2-ethylhexene aldehyde, can be reused to hydrogenation process to improve raw material utilization rate.

This invention discloses a method for preparing 3,5,5-trimethylhexanoic acid and its application, belonging to the technical field of 3,5,5-trimethylhexanoic acid preparation. The method for preparing 3,5,5-trimethylhexanoic acid includes the following steps: S1, dehydrating tert-butanol to prepare isobutylene; wherein the tert-butanol used contains <0.3% by mass of n-propanol, <0.3% by mass of isopropanol, <0.3% by mass of n-butanol, and <0.3% by mass of isobutanol; S2, preparing diisobutylene from the isobutylene obtained in S1; S3, preparing 3,5,5-trimethylhexanal from the diisobutylene obtained in S2 via hydroformylation; S4, preparing 3,5,5-trimethylhexanal from the 3,5,5-trimethylhexanal obtained in S3 via oxidation. The 3,5,5-trimethylhexanoic acid obtained by this invention has high purity.

A Pt / a-CO / TiO2 catalyst with a C–O–M dual interface and its application in VOCs purification belong to the fields of catalytic chemistry and environmental chemistry. By precisely controlling the structure and thickness of the amorphous oxygen-containing carbon layer (a-CO) on the TiO2 surface, a C–O–M (M = Pt and Ti) dual interface structure was successfully constructed, significantly improving the photothermal synergistic catalytic elimination efficiency of typical VOCs (including but not limited to pentane, heptane, octane, ethanol, hexanal, ethyl acetate, or toluene). The innovative design of the Pt / a-CO / TiO2 catalyst not only demonstrates its universal applicability for the purification of a variety of VOCs, but also opens up new ideas for the further application of photothermal catalytic technology in the field of VOCs purification. It has good application prospects in the field of air pollution control and has the potential to promote the development of environmental chemistry and catalytic chemistry technologies.

The present invention discloses a catalyst suitable for isooctenal hydrogenation, its preparation method and application. The catalyst carrier is a mesoporous alumina composite material modified by g-carbon nitride, the main active component is one or two of Ni and Co, and the second active component is one or two of Mo and W. Among them, the mass of g-carbon nitride accounts for 5-35 wt% of the carrier, preferably 15-25 wt%. The present invention significantly increases the specific surface area of the traditional alumina catalyst, improves its pore structure, enhances the dispersion degree and stability of the active component, has more stable reaction performance, mild reaction conditions, and the selectivity of 2-ethylhexanal can reach 99%.

Process for producing 3,5,5-trimethylhexanal, which is a process for producing 3,5,5-trimethylhexanal by reacting diisobutene (DIB) with carbon monoxide and hydrogen in the presence of a cobalt-based catalyst, the production process comprising: a step of reacting DIB with carbon monoxide and hydrogen in the presence of a cobalt-based catalyst until the conversion rate of DIB reaches 50 to 85% (first-stage reaction step); a step of separating unreacted DIB from the reactants obtained in the aforementioned first-stage reaction step (unreacted DIB separation step); and a step of reacting the separated unreacted DIB with carbon monoxide and hydrogen in the presence of a cobalt-based catalyst (second-stage reaction step).

The present invention discloses a bio-based packaging material and a preparation method thereof, relating to the field of polymer materials. When preparing the bio-based packaging material of the present invention, a flame-retardant crosslinking agent is prepared by reacting 6-maleimido-1-hexanal with bis(3-aminopropyl)phenylphosphine; a modified chitosan is prepared by reacting N-(2-bromoethyl)maleimide with chitosan; zinc oxide is first reacted with [3-(trimethoxysilyl)propyl]succinic anhydride and then with the modified chitosan, and finally quaternized with methyl iodide to obtain modified zinc oxide; 2,5-furandicarboxylic acid and propylene glycol are reacted to obtain a furan copolyester; the flame-retardant crosslinking agent, the modified zinc oxide and the furan copolyester are subjected to mixing, molding and heat preservation to obtain the bio-based packaging material. The bio-based packaging material prepared by the present invention has good tensile properties, flame-retardant properties, antibacterial properties and recyclability.

The disclosure provides polypeptides and encoding nucleic acids of engineered carboxylic acid reductases and / or engineered alcohol dehydrogenases. The disclosure also provides cells expressing an engineered form of the carboxylic acid reductases and / or engineered alcohol dehydrogenases. The disclosure further provides methods for producing a bioderived compound, such as 1,6 hexanediol (HDO), hexamethylenediamine (HMD), upstream precursors (e.g., adipate semi-aldehyde, 6-aminocaproic acid, 6-aminocaproate semialdehyde, 6-hydroxyhexanoic acid, 6-aminohexanol, caprolactone, caprolactam, and / or 6- hydroxyhexanal), and products derived therefrom comprising culturing cells expressing an engineered carboxylic acid reductase and / or engineered alcohol dehydrogenases.

The present invention relates to a method for preparing an at least partially acetal-protected sugar involving the step of reacting a sugar or a sugar derivative selected from the group consisting of an aldopentose, an aldohexose, an aldopentoside and an aldohexoside with an aldehyde or an aldehyde source in the presence of heterogeneous acidic catalyst to form the at least partially acetal-protected sugar selected from the group consisting of a compound of formula (I), (II), (III), (IV), (V), (VI), (VII), (VIII), (IX), (X,)(XI) and (XII) wherein R1, R1′, R2, R2′, R3, R3′, R4, R5, R6, R7, R8, R9, R10, R11, R12, and R12′ are Y or Z-E, and wherein R1 and R1′, R2 and R2′, R3 and R3′, and R12 and R12′ are the same or different from each other and Y is hydrogen or a linear, branched or cyclic hydrocarbon moiety having 1 to 20 carbon 69 atoms, Z is a linear, branched or cyclic hydrocarbon moiety with 0 to 12 carbon atoms, optionally substituted with 1 to 4 C1 to C4 alkyl groups, 1 to 4 halogen atoms, or benzyl groups and E is —COOH, —CH(COOH)2, —COOR19, —CH(COOR20)(COOR21), —CHO, —CH(CHO)2, —C2H3, CH(C2H3)2, —CHCHR22, —CHCR23R24, —C2H, —C2R25, —N3, —NH2, —CH(NH2)2, —NHR26, —CH(NHR27)(NHR28), —NR29R30, —CH(NR31R32)(NR33R34), —OH, —OR35, —CH(R36OH)(R37OH), and R19, R20, R21, R22, R23, R24, R25, R26, R27, R28, R29, R30, R31, R32, R33, R34, and R35, are independent from each other C1 to C20 alkyl, and R20 and R21, R23 and R24, R27 and R28, R29 and R30, R31 and R32, as well as R33 and R34 are the same or different from each other, and R36 and R37 are independent from each other absent or a linear or branched C1 to C12 hydrocarbon chain and R13, R14, R15, R16, R17 and R18 are independent from each other hydrogen or a linear, branched or cyclic hydrocarbon moiety having 1 to 20 carbon atoms.