67 results about "Screening programs" patented technology

A method and system for prefetching of data, such as, image data of medical images, for example, digital radiographic images, into a cache. The prefetching relies on workflow information. The method and system is particularly advantageous for use in screening programs where a large number of individuals are screened for a disease, such as cancer, in particular, breast cancer.

The present invention relates to an automatic electrode position apparatus for connecting an electrode to a cell. The invention further provides methods for utilizing the apparatus of the invention. Apparatus and methods are described for studying electrical activities in cell membranes. These methods are especially useful in large scale screening programs in the pharmaceutical industry.

The invention provides a program screening method with a mood identifying function. The program screening method includes steps of acquiring user face characteristic information and voice information; comparing the acquired user face characteristic information and the voice information with a preset historic mood comparison database to judge mood types of a user; and screening program information corresponding to the current mood type of the user according to the mood types of the user. The invention further discloses a program screening system with a mood identifying function and a television with the program screening system. By comparing the acquired user face characteristic information and the voice information with the preset historic mood comparison database to judge the mood types of the user and screening historically watched television programs and network movie programs corresponding to the mood type finally, the television program and the network movie program accordant with the mood of the current are selected on the premise of no user operation, and time for screening programs is saved for the user.

Described herein is an isolated polynucleotide encoding an LPA receptor. Also described is a recombinant DNA molecule comprising a nucleic acid encoding an LPA receptor and expression controlling elements linked therewith, as well as the use of nucleic acid coding for an LPA receptor for expression to obtain a functional receptor protein and for further gene cloning to identify structurally related receptor proteins. Also described herein is LPA receptor as a product of recombinant production in a cellular host. Described is a method of utilizing the LPA receptor in a chemical screening program to identify LPA receptor ligands. The invention further describes antibodies directed to the LPA receptor for use for example in diagnosis of conditions wherein the levels of LPA are altered.

This invention relates to methods for preparing cyclic peptides and peptidomimetic compounds in solution and bound to solid supports, and to cyclic peptide or peptidomimetic libraries for use in drug screening programs. In particular, the invention relates to a generic strategy for synthesis of cyclic peptides or peptidomimetics that enables the efficient synthesis under mild conditions of a wide variety of desired compounds. Two approaches were evaluated for their improvements in solution and solid phase synthesis of small cyclic peptides: positioning reversible N-amide substituents in the sequence; and applying native ligation chemistry in an intramolecular sense. Systematic investigation of the effects of preorganising peptides prior to cyclisation by using peptide cyclisation auxiliaries, and developing new linkers and peptide cyclisation auxiliaries to aid cyclic peptide synthesis gives surprising improvements in both yields and purity of products compared to the prior art methods. The combination of these technologies provides a powerful generic approach for the solution and solid phase synthesis of small cyclic peptides. The ring contraction and N-amide substitution technology of the invention provide improved methods for the synthesis of cyclic peptides and peptidomimetics. When used in conjunction with linker strategies, this combination provides solid-phase avenues to cyclic peptides and peptidomimetics.

Human somatic cells obtained from individuals with a genetic heart condition are reprogrammed to become induced pluripotent stem cells (iPS cells), and differentiated into cardiomyocytes for use in analysis, screening programs, and the like.

The invention relates to a discrimination method for advanced persistent threat attack. The discrimination method comprises the following steps: collecting an API (Application Program Interface) calling sequence of a terminal sample program system; extracting the API calling short sequence of the terminal sample program system through a MapReduce module, then, calculating the information gain of the short sequence, and screening program behavior characteristics with huge information gain; scanning the API calling sequence of the terminal sample program system again to obtain the behavior characteristics of a terminal sample program; using the behavior characteristics of each sample program as input by a statistical machine learning model module, training the statistical machine learning model module until the classification correction rate of the training sample program by the statistical machine learning model module is above 90%, determining a model parameter, and taking the model parameter as an APT (Advanced Persistent Threat) attack discriminator; collecting the system calling sequence of a target terminal program; and after the API calling sequence of the target program is collected and the behavior characteristics of the target program are extracted, judging whether the target program has attack behaviors. The discrimination method is high in APT attack detection capability and shortens the extraction time of program behavior characteristics.

A system for on-line dynamic screening of contingencies comprising postulated disturbances which an electric power system may experience, the system comprising a dynamic contingency screening program for evaluating a plurality of contingencies with a plurality of contingency classifiers based on the method of finding the controlling unstable equilibrium point of the power system known as the boundary of stability region based controlling unstable equilibrium point method by sequentially applying the contingencies to a network islanding problem classifier, S.E.P problem classifier, a large stability regions classifier, an exist point problem classifier, a ray adjustment problem classifier, an energy function problem classifier, a CUEP convergence problem classifier, and a controlling UEP (unstable equilibrium point) classifier to form a first group of stable contingencies and a second group of unstable or undecided contingencies, and a time-domain simulation program for determining which of the second group of contingencies are unstable.

The present invention provides methods and kits for determining the metabolic stability of compounds (e.g., stability to oxidative metabolism). In particular embodiments, the invention provides a method of determining the susceptibility of a compound to metabolism by an enzyme. In one representative embodiment, the enzyme is a cytochrome P450 enzyme. The invention is well-adapted for use in high throughput drug screening programs.

The invention relates to a parallel marine drug screening method based on a heterogeneous many-core architecture, and belongs to the technical field of drug screening, and the method comprises the steps of constructing a high-performance computing architecture of heterogeneous many cores, inputting, outputting and parallelizing a drug high-throughput screening program, scoring and optimizing a molecular structure. According to the method, the heterogeneous many-core high-performance computing architecture is utilized, so that drug screening is more efficient and accurate, and the finally screened molecular structure is simple and has a good effect on a target point.

Human pluripotent stem cells are differentiated in vitro into human cortical spheroids (hCS), which contain astrocytes, as well as cortical progenitors and neurons for use in analysis, screening programs, and the like.

An intelligent data processing method includes following steps: collecting and storing operation data of product operation equipment, and analyzing and classifying; finding and providing a product solution according to the operation data after being analyzed and classified; according to the product solution, modifying a product or displaying content of the solution. The invention further providesan intelligent data processing system. A lot of time and manpower are not needed to analyze and solve problems, and the system intelligently analyzes problems from massive data and is combined with anartificial intelligence system to constantly improve solution screening ability and select an optimal solution to finally solve the problems, so that a problem solving system is formed; once restoration fails, related personnel is notified timely for solution, so that the system can constantly improve screening programs and improve problem solving level.

The invention relates to an XLPE power cable typical defect partial discharge type identification system. The identification system is characterized by comprising a data module, a characteristic quantity extraction module, a training module and an identification module, wherein the data module is used for carrying out weight fitting on typical XLPE power cable partial discharge data measured by utilizing multiple partial discharge measurement methods; and the partial discharge data are generated energy and a corresponding phase, the obtained partial discharge data are superposed, and a partialdischarge pulse signal is obtained through a discharge screening program. According to the system, the accuracy and convergence rate of XLPE power cable partial discharge type identification can be improved.

The invention provides a television program recording method and a television program recording system. The television program recording method comprises the steps of: memorizing programs which a user made requests to watch in the past, and generating a historical playing program list; screening programs with a high playing degree of interest from the historical playing program list, and forming a reserved recording program list; receiving program data streams corresponding to television channels, and processing the program data; and judging whether program update exists in the currently playing program data stream of the television channel when compared with program information fields of the corresponding program in the reserved recording program list, if so, recording the updated program quickly and saving the recorded program in a program database. The television program recording system comprises the program database, a historical memory module, a program screening module, a data receiving module, a program update judgment module and a program updating module. The television program recording method and the television program recording system can automatically reserve program recording according to user watching records, so as to prevent the situation that the program is missed or cannot be watched timely because the program recording cannot be reserved in advance.

The invention discloses a method for screening root media by using tobacco sterile seedlings. The method comprises the following steps: A, sterilizing tobacco seeds; B, cultivating the sterile seedlings; C, shearing the sterile seedlings; D, allocating a plurality of root media to be screened; and E, screening the optimal root media. The method is simple in process, labor-saving and time-saving, economic and reliable, and can shorten the screening period effectively, simplify the screening program, and save the screening material; and the sterile seedlings materials are obtained by seeds in a culture vessel directly, and enter the stage of root screening directly, which omits the trouble of cultivating adventitious buds as compared with the conventional screening test, so that manpower, material resources and time are saved. The tobacco sterile seedlings are adopted to screen the media, and the tobacco sterile seedlings screening can synchronize with the callus induction, so that the test schedule is speeded up. Besides, the induction effect of the method is consistent with that of a method for screening root media by using adventitious buds.

Human pluripotent stem cells are differentiated in vitro into forebrain subdomain structures, which are then fused to generate an integrated system for use in analysis, screening programs, and the like.

The invention discloses a sign language translation method based on a BP neural network. The sign language translation method is characterized by comprising the following steps: 1, acquiring a gesturevoltage signal by utilizing Raspberry Pi 3B through a wearable data glove; 2, compiling sign language words and common sign language sentences corresponding to each group of gesture voltage signals into a sign language sentence library by utilizing a signal screening program; 3, writing a neural network classification program comprising a BP neural network structure framework model, a data transmission module and a storage module, wherein the BP neural network structure framework model adopts a three-layer neural network comprising an input layer, an output layer and a hidden layer; 4, converting the gesture voltage signals received each time into sign language words through a BP neural network framework model; and 5, converting the sign language words obtained in the step 4 into sign language word groups within a period of time, matching the sign language word groups with a sign language statement library, associating and filling into sentences, and outputting a result. According tothe invention, automatic real-time translation identification of sign language is realized by combining a neural network and a sensing technology.

In some embodiments, a call urgency screening system may include one or more of the following features: (a) a data storage device comprising, (i) a call urgency screening program that allows a recipient to choose whether to accept a call from a caller or offer to the caller other alternate call handling of the call based on interaction with the caller and a dialog engine, and (b) a processor coupled to the data storage device that executes the call urgency screening program.

The present invention relates to biomarkers useful for detection of types, grades and stages of human breast cancer. The present invention particularly relates to the development of these identified biomarkers as a miRNA chip for the early and accurate diagnosis of human breast cancer. This patent application highlights the novelty in the utility of these miRNAs, that they could be used as a diagnostic kit (miRNA chip) for early and accurate detection of breast cancer grades, stages and subtypes. Few to hundreds of samples can be checked within a span of 2 to 3 hrs and hence this becomes an easy, fast, robust and high throughput technology for screening program for early detection of breast cancer.

The present invention provides methods and kits for determining the metabolic stability of compounds (e.g., stability to oxidative metabolism). In particular embodiments, the invention provides a method of determining the susceptibility of a compound to metabolism by an enzyme. In one representative embodiment, the enzyme is a cytochrome P450 enzyme. The invention is well-adapted for use in high throughput drug screening programs.

The invention provides a software performance risk detection method and device, and the method comprises the steps: obtaining a to-be-detected software program set, screening programs with performancerisks according to predefined performance indexes, and generating a risk program set; processing the operation behaviors of the programs in the risk program set to obtain logic feature vectors; and performing risk detection by utilizing the logic feature vector. The software performance risk detection method provided by the invention comprises index definition, risk identification and behavior analysis, feature storage, risk learning, operation management and the like. The performance risk can be prevented from influencing the operation of the software, and a guarantee is provided for performance risk identification in the early stage of software research and development, so that possible risk problems can be optimized in the research and development stage.

In a screening program, the Antarctic sponge Dendrilla membranosa was found to produce diterpenoid secondary metabolites with activity against the leishmaniasis-causing parasite Leishmania donovani. The present invention concerns compositions useful for control of Leishmania spp. parasites in vitro and in vivo and treatment of leishmaniasis; methods for treatment of leishmaniasis; and methods for controlling Leishmania spp. parasites in vitro and in vivo.

The invention discloses a personalized content recommendation method and device and a storage medium. The method comprises the following steps: generating a program label for each program in a film and television library; collecting user behavior data, and generating a user current label according to the user behavior data and the current watching time; screening programs in a film and televisionlibrary according to the current label of the user to obtain a plurality of recommended programs; performing weighted integral calculation on the recommended programs by utilizing the current user label and the program labels of the recommended programs to obtain recommended values of the recommended programs; and displaying the recommended programs and the recommended values corresponding to therecommended programs to the user. According to the invention, the personalized label and the program label are used for scoring according to the preset scoring rule, the recommended resources are output to the user according to the scores of the resources, automation and personalization of content recommendation are achieved, meanwhile, the recommendation result is more accurate, and the preference of the user is met.

Human somatic cells obtained from individuals with a genetic heart condition are reprogrammed to become induced pluripotent stem cells (iPS cells), and differentiated into cardiomyocytes for use in analysis, screening programs, and the like.

Human pluripotent stem cells are differentiated in vitro into forebrain subdomain structures, which are then fused to generate an integrated system for use in analysis, screening programs, and the like.

Human pluripotent stem cells are differentiated in vitro into oligodendro-spheroids comprising oligodendrocytes for use in analysis, screening programs, and the like.

The invention discloses a fungus expression vector. The expression vector is a constructive expression vector which consists of a plasmid expression vector pEX and an acidic trehalase gene serving as a screening marker, wherein the plasmid expression vector pEX is formed by removing a Bar gene in an expression vector pBarEx; and the screening marker gene belongs to acidic trehalase genes such as an ataxia telangiectasia mutated (ATM) gene or an ancient technology activation (ATA) gene. In the invention, a safe and environment-friendly screening marker is used for the fungus expression vector,and insect pathogen project fungi constructed by the fungus expression vector are released to the environment and cannot adversely influence the environment due to the screening marker. The fungus expression vector has a unique design principle, an ingenious construction method, a simple program, a simple screening program for an insect pathogen fungus transgenic bacterial strain of the fungus expression vector and high screening efficiency, does not influence the metabolic balance of the fungi, and has a potential and wide application prospect in the transgenic fungus research and marketization process.