A kind of probe and its preparation method and application
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of probes and reactants, applied in the field of probes and their preparation, can solve problems such as threats to health, difficulty in rapid decomposition, long-term residue, etc., and achieve direct analysis, simple operation, and visible test results
Active Publication Date: 2019-04-26
GUIZHOU UNIV
View PDF7 Cites 0 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
Especially heavy metal ions are not easy to decompose quickly after entering the environment so that they can remain in the environment for a long time; and after entering the human body, they seriously threaten human health
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0039] Embodiment 1: a kind of probe, the molecular formula of described probe is: C 40 h 45 N 4 Br, the structural formula of the probe is attached figure 1 Shown; NMR spectrum as attached Image 6 shown.
Embodiment 2
[0040] Embodiment 2: a kind of preparation method of the probe described in embodiment 1, its steps are as follows:
[0041] (1) Using 4-bromobenzaldehyde, 2-acetylpyridine, 4-pyridineethylene and brominated alkanes, ammonia water, palladium acetate, triphenylphosphine, triethylamine and dimethylformamide (DMF) as raw materials, at 3°C Stir for 2 hours, reflux for 22 hours, and stir at room temperature for 45 minutes to obtain a precipitate, filter it, and recrystallize in acetic acid to obtain a reactant;
[0042] (2) The reactant in step (1) was taken out and cooled to room temperature to produce a precipitate, which was filtered to obtain a solid, and then the solid was dried to obtain a probe.
Embodiment 3
[0043] Embodiment 3: a kind of preparation method of the probe described in embodiment 1, its steps are as follows:
[0044] (1) With 4-bromobenzaldehyde, 2-acetylpyridine, 4-pyridineethylene and brominated alkanes, ammonia water, palladium acetate, triphenylphosphine, triethylamine and dimethylformamide (DMF) at 0°C Stir for 3 hours, reflux for 18 hours, and stir at room temperature for 30 minutes to obtain a precipitate, filter it, and recrystallize in acetic acid to obtain a reactant;
[0045] (2) The reactant in step (1) was taken out and cooled to room temperature to produce a precipitate, which was filtered to obtain a solid, and then the solid was dried to obtain a probe.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention discloses a probe and a preparation method and application thereof. The preparation method includes mixing and stirring 4-bromobenzaldehyde, 2-acetylpyridine, 4-vinyl pyridine, brominated alkanes, ammonium hydroxide, palladium acetate, triphenyl phasphine, triethylamine and DMF (dimethylformamide) prior to reflux, stirring for 1 hour at a room temperature to obtain a precipitate, filtering and recrystallizing in acetic acid so as to obtain a reactant; taking the reactant out, cooling the reactant to the room temperature to generate a precipitate, filtering to obtain a solid and drying the solid so as to obtain the probe. The probe is capable of quantitatively analyzing Zn<2+> concentration in a solution and has the advantages of low quantitative analysis concentration, high anti-interference capability, simplicity in operation, visual results and simplicity and convenience in analysis.
Description
technical field [0001] The invention relates to a probe and its preparation method and application, in particular to a fluorescent probe and its preparation method and application. Background technique [0002] The pollution problem caused by metals and their related ions is a serious environmental and social problem. Especially heavy metal ions are not easy to decompose quickly after entering the environment so that they can remain in the environment for a long time; and after entering the human body, they seriously threaten human health. For example, zinc ion, which is the second most abundant transition metal ion, plays an important role in many physiological processes, such as structural and catalytic factors, signal transmission and regulation, gene expression regulation and cell apoptosis. Studies have shown that the imbalance of zinc ion metabolism is closely related to many serious neurological diseases, such as Alzheimer's disease, amyotrophic lateral sclerosis, Pa...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more