188 results about "Isonicotinic acid" patented technology

The invention provides a method for preparing a metal ion imprinting adsorbent with an underwater selective recognition performance. The method comprises the steps of: preparation of an amino functional material: dispersing a nuclear body material into a methanol solution, slowly adding 3-propylaminoethoxy silane, uniformly stirring, and then, continuously adding a cross-linking agent and a stabilizer to form the amino functional material; and preparation of the metal ion imprinting adsorbent: dispersing the amino functional material in the methanol solution, and exposing to ultrasound to obtain a solution A; dissolving isonicotinic acid and metal template ions in deionized water to form a solution B; dripping the solution B into the solution A, and reacting to obtain a white sol-like product; and eluting the metal template ions: performing Soxhlet extraction by using an acetic acid-methanol solution, then eluting the metal template ions by using a hydrochloric acid, and drying to obtain the metal ion imprinting adsorbent. The metal ion imprinting adsorbent disclosed by the invention can be widely applied to advanced treatment of drinking water as well as enrichment recovery or rapid analysis detection of metal ions in different water bodies, such as industrial waste water, aquaculture water and seawater.

The invention provides a test method, which includes the following steps: distilling soil in pH<2 acidic medium, hydrogen cyanide is formed, absorbing with the sodium hydrate solution, and analyzing total cyanide in soil with isonicotinic acid-barbituric acid spectrophotometry. The invention has the advantages of good sensitivity and good repeatability, which provides a convenient and reliable method for analyzing total cyanide in soil, and meets the needs of soil pollutant analysis as well as research work.

The invention discloses a metal organic framework material as well as a preparation method and an application thereof. The material comprises components of raw materials as follows: zinc halide, a nitrogen-rich ligand and a second ligand, wherein the nitrogen-rich ligand is imidazole or adenine, and the second ligand is isonicotinic acid. The metal organic framework material facilitates adsorption and activation of CO2; the cycle opening capacity of epoxides is improved and CO2 is further activated due to introduction of nucleophilic halogen, so that the CO2 reaction is promoted, and the material has high catalytic activity for a CO2 cycloaddition reaction.

The invention discloses an electroplating liquid for pulse electroplating for a compact silver film on a ceramic surface and an electroplating method thereof. The electroplating liquid comprises 2-50g / L of silver citrate, 10-120g / L of 2-sulpho-5,5-dimethyl hydantoin, 10-50g / L of succinimide, 10-50g / L of potassium hydroxide, 10-40g / L of potassium citrate, 1-3g / L of ammonium molybdate, 0.5-2g / L of polyethylene glycol, 20-150g / L of sodium sulphite, and 5-20g / L of isonicotinic acid, wherein the pH value of the electroplating liquid is adjusted to 8-10 by virtue of potassium hydroxide, and the temperature of the electroplating liquid is kept at 25-45 DEG C; and the ceramic pre-plated metal layer surface is electroplated by a square-wave pulse current method, and a layer of compact silver film can be electrodeposited. The electroplating liquid is high in stability; and the plating layers obtained by the pulse electroplating method are smooth and compact, uniform in brightness, and high in performance of binding with a ceramic matrix.

The invention discloses a method for determining and correcting cyanide. The method is characterized by comprising the following steps of: 1) putting 10 milliliters of distillate in a colorimetric tube which has a volume of 25 milliliters and is provided with a plug; 2) adding 5 milliliters of phosphate buffer solution into the tube, mixing uniformly, quickly adding 0.2 milliliter of chloramine solution, immediately inserting the plug, mixing uniformly and placing for 3 to 5 minutes; 3) adding 5 milliliters of isonicotinic acid-pyrazolone mixed solution into the tube, uniformly mixing, adding water to dilute until mixture reaches a marked line, shaking uniformly, and placing in an aqueous solution at the temperature of between 25 and 35 DEG C for 40 minutes; and 4) determining absorbance by using a cuvette with height of 1cm, and using reagent blank as reference at the wave length of 638nm, and finding out the corresponding cyanide content from the standard curve. By using an intermediate medium, the cost of purchasing, storing and managing toxic and dangerous chemicals is reduced, and potential unsafe factors of the toxic and dangerous chemicals in using operation can be reduced.

The invention discloses two fluorinated metal organic framework materials, preparation and low-carbon hydrocarbon separation application thereof, and belongs to the technical field of crystalline porous material preparation and gas separation. The two microporous copper-based MOF materials are formed by a cheap and easily available multi-coordination organic ligand 3-fluoroisonicotinic acid (FINA)and copper nitrate under different solvothermal conditions. The two MOF crystal structures have high porosity and have regular one-dimensional channels, the size of the channels is slightly larger than the molecular dynamics size of low-carbon hydrocarbon, and a structural basis is provided for adsorption separation of the low-carbon hydrocarbon gas molecules. Besides, hydrogen bond interaction sites exist in the pore channels, and alkyne molecules with smaller kinetic sizes can enter the pore channels easily after the pore channels are cut by fluorine atoms, and the acting force between alkyne gas molecules and the framework is enhanced so that the effect of preferentially adsorbing acetylene gas in acetylene-ethylene mixed gas and preferentially adsorbing propyne in propyne-propylene mixed gas is achieved, ethylene and propylene components in the mixed gas are purified, and the energy consumption in the separation process is reduced.

The invention relates to a Method for preparation of 4-aminopyridine. This invention is based on the Hofmann degradation rezction of iosniacinamide to prepare 4-aminopyridine, making catalyzer by low-cost iodine or alkali metal iodide, sodium hydroxide orporassium hudroxide and bromine according to certain proportion and condition. The productivity of Hofmann degradation rezction of iosniacinamide is improved above 90%, the purity of 4-aminopyridine is higher than 99%. This can not only improve the productivity of 4-aminopyridine which is made by isonicotinic acid, but also reduce the cost of catalyzer greatly. It has important application-value to prepare 4-aminopyridine which is made by isonicotinic acid.

The invention relates to a detection reagent for fast detecting cyanide in water. The detection reagent comprises a release reagent and a color developing reagent, wherein the release reagent comprises monopotassium phosphate, methylcellulose, lactic acid and acetone mixed solvents and chloramine T, the color developing reagent comprises sodium hydroxide, isonicotinic acid, barbituric acid and methylcellulose, and the release reagent and the color developing reagent are encapsulated in a separated way according to the consumption for each time. The release reagent comprises the preparation steps that: 1, major ingredients and deionized water are mixed and ground into paste; 2, the paste is placed in a vacuum drying box for drying; 3, dried materials are cooled and ground into powder; 4, the lactic acid and acetone mixed solvents are used for preparing 5% chloramine T solution; and 5, the chloramine T solution is added into the prepared powder, the materials are dried in the air, and the powdery release reagent is obtained. The preparation steps of the release reagent refer to the partial steps. The detection reagent disclosed by the invention can be matched with a colorimetric tube and a standard colorimetric card to be used, the carrying is convenient, the detection range is wide, the time is short, and convenience can be provided for the fast detection of the cyanide in water in various sites.

The invention relates to isoalantolactone derivatives and salts thereof and provides an isoalantolactone derivative as shown in a formula (I). Salification acids are selected from inorganic acids or organic acids; the inorganic acids are selected from hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boric acid, seleninic acid, phosphomolybdic acid, phosphorous acid and sulphurous acid; the organic acids are selected from citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-acid, oxalic acid, methylsulfonic acid, pentanoic acid, oleic acid, lauric acid, p-toluene sulfonic acid, 1-naphthalenesulfonic acid, 2-naphthalenesulfonic acid, phthalic acid, tartaric acid, malonic acid, succinic acid, fumaric acid, glycolic acid, mercaptan acid, glycine, sarcosine, sulfonic acid, nicotinic acid, methylpyridine acid, isonicotinic acid, benzoic acid or substituted benzoic acid.

The invention belongs to the technical field of medicine, and provides substituted mercaptonicotinic acid compounds and a preparation method thereof. The structural general formula of the compounds is shown as formula I described in the specification, and the compounds comprise a pharmaceutically acceptable salt, ester and solvate. A substituted aniline compound is used as a raw material and reacted with chloroacetyl chloride or bromoacetyl chloride to generate amide, and then the amide is reacted with a mercapto-substituted nicotinic acid or isonicotinic acid compound to obtain the mercaptonicotinic acid compounds. The invention further provides an application of the compounds in a medicament.

The invention discloses a process for one-step air catalytic oxidation synthesis of picolinic acid type compounds, particularly picolinic acid type compounds comprising 2-picolinic acid, nicotinic acid and isonicotinic acid. According to the process, a continuous fixed bed reactor is adopted, air or oxygen-rich air is adopted as an oxidant, methylpyridine is prepared by one-step oxidation under the action of a catalyst and is then subjected to desublimation to obtain a picolinic acid product, and after the product in reaction gas is separated, the reaction gas is returned to the reactor, reacts and is recycled. The process has advantages of simple process operation, low raw material cost, high yield, low energy consumption, capability of being free of generation of harmful waste gas and waste liquid in the preparation process, capability of being widely used for industrial production of the picolinic acid, and the like.

The invention discloses a photochromic nylon fiber and a preparation method thereof. The photochromic nylon fiber is composed of the following components in parts by weight: 6-100 parts of nylon, 1-5 parts of photochromic material, and 1-10 parts of spinning auxiliary; the photochromic material is selected from phosphomolybdic acid isonicotinic acid, spiropyrane derivatives or azobenzenes. The photochromic nylon fiber disclosed by the invention has the beneficial effect that the obtained photochromic nylon fiber can become as yellow green from primary faint yellow under the effect of ultraviolet light; and the discoloring function cannot be lost along the time, the processing is simple and the industrial implementation is convenient; the photochromic nylon fiber has great application prospect in the fields of national defenses, civilian use and counterfeiting prevention.

The invention relates to a method for quickly detecting pesticide residue of cyanogens-containing synthetic pyrethroids in tea. The method comprises the following steps of: leaching cyanogens-containing synthetic pyrethroids in tea in advance; removing interference components in the tea and then heating the pesticide residue of cyanogens-containing synthetic pyrethroids for full alkaline hydrolysis to generate cryanide ions; adding acid to generate HCN (Hydrocyanic Acid) gas; transferring, absorbing and measuring the concentration of a CN (Cyanide) ion by using an air suction device; and realizing accurate quantitative measurement by using thiocyanate-isonicotinic acid pyrazolone spectrophotometry development. According to the method, an alkaline hydrolysis reaction and HCN gas transfer are thoroughly realized by heating, stirring and extracting air, thus the detection sensitivity is high; and meanwhile, interference substances in the tea are eliminated so as to facilitate the accurate quantitative detection. In addition, the method has low cost, is realized by adopting simple equipment, is simple and convenient and is easy to popularize; and the strict on technical requirements is inferior to that of instrument analysis; and the method is a simple accurate analysis method for detecting pesticide residue of fresh leaves in the production of tea and analyzing the quality of finished tea.

The invention relates to novel heterocyclic compounds and to the use thereof, to pharmaceutical compositions containing said chemical compounds as an active ingredient and to the use thereof for producing medicinal preparations for the human being and warm-blood animals for treating diseases caused by the aberrant activity of an Hedgehog (Hh)-signal system, in particular oncological diseases. The invention also relates to the use of the above-mentioned compounds in the form of ‘molecular pharmacological tools’ for examining (in vitro and in vivo) the biochemical features of the Hh-signal system, in particular, the interaction of Hh protein and transmembrane proteins, namely, suppressor Patched (Ptc) and protooncogenic proteins. The eight groups of the claimed compounds comprise the derivatives of 2,6-dihydro-7H-pyrazolo[3,4-d]pyridazine-7-one and 1,4-dihydropyrazolo[3,4-b][1,4]thiazine-5-one; N-acidylated 4-imidazo[1,2-a]pyrimidine-2-il-anilines; ([4H-thino[3,2-b]pyrrol-5-il) carbonyl]piperidine-4-carbonic acid amides; 2-(4carbomoilpyperidine-1-il)-isonicotinic acid amides; N-sylphonyl-1,2,3,4-tetrahydroquinoline-6-carbonic acid amides; and pyridine 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]N-acidylated 3-azole derivatives.

The present invention relates to new processes for the preparation of 2-cyclopentyl-6-methoxy-isonicotinic acid, which is a useful intermediate for the synthesis of pyridine-4-yl derivatives as immunomodulating agent. Moreover, the present invention also relates to new intermediates used in those processes.

The present invention provides a cotton topping agent, which comprises, by weight, 0.8-2 parts of paichongding, 0.8-2 parts of hydroxypropylmethylcellulose, 3-6 parts of beta-methylnaphthalene, 5-10 parts of fosamine-ammonium, 10-15 parts of isonicotinic acid, 10-15 parts of iodophenoxyacetic acid, 15-20 parts of p-chlorotoluene, and 15-20 parts of sodium disec-octyl maleate sulfonate. According to the present invention, the cotton topping agent is organically dissolved, such that the cotton top can be killed, the cotton length can be effectively controlled, the ideal plant type can be shaped,the flower and the bud can be retained, the photosynthesis of cotton can be enhanced, the cotton boll can be increased, the diseases can be prevented and controlled, the boll opening early maturity can be achieved in advance by more than seven days, the micronaire value of cotton is not affected, and the purposes of high yield and stable production are achieved.

The invention discloses a topiroxostat impurity synthesis method, and belongs to the chemical pharmaceutical technical field. The method comprises the steps: with methyl isonicotinic acid-N-oxide (2) as a starting material, generating 2-cyano-4-pyridine carboxylic acid methyl ester from methyl isonicotinic acid-N-oxide (2) and trimethylsilyl cyanide; carrying out hydrazinolysis of the compound (3) to generate 2-cyano-isoniazid (4); and carrying out ring self-formation of the compound (4) to generate a target 2-(3-(2-amino pyridine-4-yl)-1H-1,2,4-triazole-5-yl)isoniazide (1). The synthesized high-purity topiroxostat impurity can be used as an impurity standard in topiroxostat finished product detection analysis, so as to enhance accurate positioning and qualitation on the impurity in the topiroxostat finished product detection analysis, be conducive to strengthening of the control of the impurity, and improve the quality of the topiroxostat finished product; the method provided by the invention has the advantages of cheap and easily obtained raw materials, and simple operation; the yield of the obtained product is 85%+ / -5%, and the HPLC purity is not less than 98%.

The invention discloses a preparation method of isoniazid. The method comprises the following steps: 1) performing esterification reaction to isonicotinic acid, alcohol and acylating reagent to obtain isonicotinic acid ester; 2) performing condensation reaction to isonicotinic acid ester and hydrazine hydrate and performing post-treatment to reaction liquid to obtain isoniazid finished products. The isoniazid is prepared firstly through esterification of isonicotinic acid and alcohol and then condensation of the obtained ester and hydrazine hydrate. The method can well control the content of impurities in the target product isoniazid, high-purity isoniazid can be obtained, the purity is above 99.9 percent and the content of individual impurity is smaller than 0.10 percent. The method is simple to operate, is easy to control and is applicable to industrial operation. In addition, by using recovered isonicotinic acid to prepare isoniazid, the cyclic utilization of resources can be realized, the waste emission is reduced, the cost is reduced and the method is very suitable for industrial production.

The invention relates to a measurement method for total cyanide in solid wastes containing thiocyanate and sulfide, and belongs to the technical field of total cyanide measurement in solid wastes. Themeasurement method comprises the following steps: selecting a reasonable weighing sample, using ethyl alcohol as a dispersing agent, adding distilled water to further increase the dispersibility of the cyanogens-containing solid wastes, adding silver nitrate to shelter the interference of thiocyanate and sulfide, and adopting a sodium hydroxide solution as absorption liquid. When the content of the cyanide inside a sample is greater than 100 mg / kg, silver nitrate titration is used for measurement, and when the content of the cyanide inside the sample is greater than 100 mg / kg, isonicotinic acid-pyrazolone spectrophotometry is used for measurement. The ethyl alcohol is successfully found as the dispersing agent, and the silver nitrate is successfully found as a masking agent for masking thiocyanate and sulfide. According to the method, the content of total cyanide in the cyanogens-containing solid wastes containing thiocyanate and sulfide can be measured accurately.

The invention discloses a method for preparing isonicotinic acid without catalytic hydrolysis of isonicotinic nitrile in near-critical water medium. The method comprises the following steps: 1) deionized water and the isonicotinic nitrile with the mass ratio of 2 to 1 to 8 to 1 are added into a high-pressure reactor kettle and stirred. Under normal pressure, the temperature is raised until the liquid boils. An exhaust valve is opened for 2-5min; 2) the exhaust valve is closed, and the temperature is continuously raised to 200-300 DEG C for the hydrolysis for 30-600min; 3) hydrolytic products are cooled, the pH value is regulated to 3-4, and after the crystallization, crude isonicotinic acid is obtained; 4) the crude isonicotinic acid is dissolved in hot water and after decolorizing by activated carbon, secondary crystallization and vacuum drying, the isonicotinic acid products are obtained. During the reaction, no catalysts are required to be added, and the hard problem of pollution caused by acid and alkaline catalytic hydrolysis is solved. The method has the advantages of simple and green process and high purity and yield of products.

The invention relates to an application of an isoalantolactone derivative and a salt thereof in the preparation of medicines for treating lung fibration, and provides an isoalantolactone derivative represented by formula (I). An acid for forming the salt is an inorganic acid or an organic acid, the inorganic acid is selected from hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boric acid, seleninic acid, phosphomolybdic acid, phosphorous acid and sulfurous acid, and the organic acid is selected from citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-lactic acid, oxalic acid, methanesulfonic acid, pentanoic acid, oleic acid, lauric acid, p-methyl benzenesulfonic acid, 1-naphthalenesulfonic acid, 2-naphthalenesulfonic acid, phthalic acid, tartaric acid, propane diacid, succinic acid, fumaric acid, glycollic acid, thioglycollic acid, glycine, sarcosine, sulfonic acid, nicotinic acid, methylpyridine acid, isonicotinic acid, benzoic acid and substituted benzoic acid.

The invention belongs to the technical field of a pharmaceutical co-crystal, and particularly relates to a novel febuxostat pharmaceutical co-crystal and a preparation method thereof. The space group of piracetam pharmaceutical co-crystal prepared by the invention is a monoclinic system, one isonicotinic acid molecule and two febuxostat molecules are combined together through a hydrogen bond respectively to form a basic structural unit of the febuxostat pharmaceutical co-crystal. A solvent selected in a preparation process of pharmaceutical co-crystal is ethyl acetate, and a solvent room temperature volatilization method is adopted. Due to a relatively low boiling point of the selected organic solvent, crystal is separated out during the process of solvent volatilization. The pharmaceutical co-crystal prepared by the invention inherits characteristics of traditional medicaments in preparing hyperuricemia of gout patients, and also has obvious change on solubility, stability and bioavailability.

The invention discloses a method for simultaneously preparing pyrazinamide and isonicotinic acid through uncatalyzed hydrolysis of isonicotinic nitrile in a near critical water medium. The method comprises the following steps: adding deionized water and the isonicotinic nitrile into a high-pressure reaction kettle, stirring the mixture, raising the temperature to the boiling point at normal pressure, and opening an exhaust valve for 2 to 5 minutes; closing the exhaust valve, continuously raising the temperature to be between 200 and 300 DEG C, and hydrolyzing for 10 to 15 minutes; cooling hydrolysate, adjusting the pH value of the hydrolysate to be between 3 and 4, performing crystallization and filtration on the hydrolysate and obtaining coarse isonicotinic acid and filtrate; making the coarse isonicotinic acid subjected to hot-water dissolution, activated carbon decolorization, secondary crystallization and vacuum drying and obtaining isonicotinic acid products; adjusting the pH value of the filtrate to be between 8 and 9, performing crystallization and obtaining coarse pyrazinamide; and making the coarse pyrazinamide subjected to hot-water dissolution, activated carbon decolorization, secondary crystallization and vacuum drying and obtaining pyrazinamide products. The method does not add any catalyst during reaction, solves the pollution problem of acid and alkali catalyzed hydrolysis, has simple and green process, and has high purity and yield of the products.

The invention provides a blind hole filling electroplating copper solution. The electroplating copper solution comprises the components of 40g / L to 120g / L of sulfuric acid, 120g / L to 240g / L of coppersulfate pentahydrate, 40ppm to 80ppm of chloride ions, 0.2ml / L to 2ml / L of an accelerator, 10ml / L to 30ml / L of an inhibitor, and 1ml / L to 10ml / L of a leveling agent. The leveling agent is an aqueous solution formed by mixing isonicotinic acid compounds and oligomeric quaternary ammonium compounds according to the mass ratio of 1 to 2 or 2 to 1. The solute concentration of the leveling agent is 10g / L. Because of the mutual collaborative mating action between the isonicotinic acid compounds and oligomeric quaternary ammonium compounds in the leveling agent and the other components in the electroplating copper solution, the blind hole filling electroplating process is taken under effective control, it is achieved that the surfaces of filled blind holes are good in smoothness, and sunken partsor protruding parts on the surfaces of hole ports of the filled blind holes are smaller than 5 microns in size.

The invention discloses a preparation method of a crystal material {[NH4][TbCu(ina)4(CN)].2DMF}n with the function of selectively adsorbing organic dye. The method comprises the steps that hydrogen sulfide is introduced into an ammonia solution of tungstic acid for a reaction, and suction filtration and drying are carried out to obtain ammonium tetrathiotungstate; the ammonium tetrathiotungstate and cuprous cyanide are added into N,N'-dimethyl formamide and stirred to obtain an orange red solution; isonicotinic acid is added into the obtained orange red solution, stirring is performed, ammonium hydroxide is dropwise added, the mixture is filtered after being completely dissolved, an acetonitrile solution containing terbium nitrate is added to the upper layer of filtrate, crystallization, filtration, washing and drying are performed, and therefore the crystal material {[NH4][TbCu(ina)4(CN)].2DMF}n is obtained. The preparation method has the advantage that the crystal material {[NH4][TbCu(ina)4(CN)].2DMF}n with the function of selectively adsorbing the organic dye is obtained.

The invention discloses a detection device and a detection method for continuous flow of total cyanide in water. The detection method comprises the following steps: firstly, decomposing complex cyanide in a sample flow through an ultraviolet lamp under a condition of weak acidic medium; filtering stray light by using a borosilicate glass spiral pipe; carrying out on-line vacuum distilling; causing a processed to-be-detected water sample to be mixed and reacted with chlorine ammonia-T reactant, isonicotinic acid and 1,3-dimethyl barbituric acid color developing agent at different flow speeds; performing continuous flow sampling on a solution after reacting; and injecting a spectrophotometer for detecting. According to the detection method provided by the invention, the operation is simple; the quantity of the required reagent and sample is small; the detection speed is high; the limit of detection is lower and the precision and the accuracy are excellent; the detection method is applied to the accurate and quick detection for the total cyanide in an unstable sample with serious matrix interference, such as seawater; and the detection method is suitable for the detection for the total cyanide in mass samples, such as surface water, underground water and water at draining outlets.

The invention discloses a method for preparing a light-emitting crystal material [WS4Cu4(SCN)4Tb2(INA)4(HMPA)8]n with a picric acid detecting function. Hydrogen sulfide is introduced into an ammonia water solution of tungstic acid to react, and ammonium tetrathiotungstate is prepared through suction filtration and drying; ammonium tetrathiotungstate and cuprous thiocyanate are added into a hexamethylphosphoric triamide solvent to prepare a solution, isonicotinic acid is added into the prepared solution to be stirred and dissolved, and after a red clear solution is prepared, the pH of the solution is adjusted to range from 8 to 10; a solution of terbium trinitrate is added into the red clear solution, and the light-emitting crystal material [WS4Cu4(SCN)4Tb2(INA)4(HMPA)8]n is obtained through crystallization, filtration, washing and drying. The method has the advantage that the light-emitting crystal material [WS4Cu4(SCN)4Tb2(INA)4(HMPA)8]n capable of efficiently detecting picric acid is obtained.

The invention provides a CeO2-based nano electrocatalytic hydrogen evolution catalyst. The CeO2-based nano electrocatalytic hydrogen evolution catalyst is prepared from porous nickel and transition metal doped CeO2 which is loaded on the porous nickel, wherein the transition metal is selected from at least one of Co<2+> and Ni<2+>; the transition metal is uniformly dispersed in the CeO2. A preparation method of the CeO2-based nano electrocatalytic hydrogen evolution catalyst comprises the following steps: synthesizing a porous nickel loaded Ce-based metal organic framework containing transition metal M by taking Ce<3+> and the transition metal M as metal ions, isonicotinic acid as an organic ligand and the porous nickel as a carrier, wherein M is selected from at least one of Co<2+> and Ni<2+>; roasting the porous nickel loaded Ce-based metal organic framework containing the transition metal M in air, thus obtaining the CeO2-based nano electrocatalytic hydrogen evolution catalyst. Transition metal ions in the CeO2-based nano electrocatalytic hydrogen evolution catalyst provided by the invention are uniformly dispersed in a CeO2 matrix, and meanwhile, the CeO2-based nano electrocatalytic hydrogen evolution catalyst as large specific surface area and high electrocatalytic hydrogen evolution activity.

The invention relates a three-dimensional azido copper-nickel coordination compound which contains a three-dimensional network structure with a one-dimensional pore canal. A secondary structural unit of the three-dimensional azido copper-nickel coordination compound is a crystal which pertains to a monoclinic system with the space group of C2 / c; an azido-bridged copper-nickel unit forms a one-dimensional chain with which univalent anions of isonicotinic acid is connected to form a three-dimensional network and during the connection process, a one-dimensional pore canal is formed between the anions of isonicotinic acid. The preparation method of the three-dimensional azido copper-nickel coordination compound comprises the steps that isonicotinic acid, copper chloride, nickelous chloride and sodium azide are dissolved in 15ml of water to produce massive crystals of the three-dimensional azido copper-nickel coordination compound through a hydro-thermal reaction. The three-dimensional azido copper-nickel coordination compound has the advantages of magnetism and magnetic variation and can be applied as molecule-based magnetic materials, thus having good application prospect in the field of material science.

The invention discloses a cyanide-free gold-plated electroplating liquid and method for electroplating the ceramic surface with a dense gold thin film through pulses. The electroplating liquid is prepared from 2-50 g / L of gold organic silicate, 10-120 g / L of 2-sulfo-5,5-dimethyl hydantoin, 10-50 g / L of succinimide, 40-100 g / L of potassium citrate, 10-40 g / L of citric acid, 1-3 g / L of antimony potassium tartrate, 0.5-2 g / L of polyethylene glycol, 20-150 g / L of sodium sulfite and 2-10 g / L of isonicotinic acid. The pH value is 5+ / -0.5. The ceramic pre-plated metal layer surface is electroplated through a square-wave pulse electric potential method or a square-wave pulse current method so that the dense gold thin film can be deposited electrically. The electroplating liquid is high in stability; the plated layer obtained through the pulse electroplating method is highly smooth and dense, uniform in luminance and high in binding force with a ceramic matrix.