89results about How to "Qualitative high" patented technology

The invention discloses a system for predicting geologic hazard based on rainfall intensity, moisture content of slope soil and deformation. The system comprises an automatic rainfall gauge, a soil moisture sensor, an omnibearing tilt sensor, an omnibearing vision sensor, an embedded system and a monitoring center computer, wherein the automatic rainfall gauge is used for monitoring rainfall and rainfall intensity of a geologic hazard point; the soil moisture sensor is used for monitoring moisture in soil at the geologic hazard point; the omnibearing tilt sensor is used for detecting earth surface deformation and internal deformation of the geologic hazard point; the omnibearing vision sensor is used for evaluating geologic hazard scale; the embedded system is used for wirelessly transmitting video and monitoring data; and the monitoring center computer is used for predicting and forecasting the geologic hazard and comprises a communication module, a data receiving module, a rainfall and rainfall intensity-based geologic hazard prediction module, a slope displacement-time curve-based geologic hazard prediction module, a soil moisture, rainfall and rainfall intensity-based geologichazard prediction module and a soil moisture content and slope deformation-based geologic hazard prediction module. The system has the advantages of complete monitoring means, accurate prediction andforecast, high intelligence and on-line real time.

The invention relates to a qualitative and quantitative analysis method for polyoses, which comprises the following steps: (1) the zymohydrolysis and the verification of the polyoses: measuring the content of a polyoses water solution by a colorimetric method; (2) comparing the change of a polyoses mapping before and after zymohydrolysis by HPSEC-ELSD analysis; (3) saccharide ingredient direct HPLC analysis of a polyoses zymohydrolysis solution or HPLC analysis after pre-column derivatization: identifying polyoses mapping and chromatogram peaks by taking a standard monosaccharose, a uronic acid, a disaccharide, and the like as contrasts and taking a chromatogram peak mass-to-charge ratio as reference, and using stable characteristic sections as a quantitative analysis index; and (4) realizing the qualitative and quantitative analysis of the polyoses by establishing polyoses zymohydrolysis responding characteristics and polyoses zymohydrolysis mapping which are based on structural information through the independent or combining application of the steps. The qualitative and quantitative analysis method can be used for the identification and quantitative measurement of the polyoses of traditional Chinese medicine, such as panax, panax pseudoginseng, gen-seng, aweto, cordyceps, ganoderma lucidum, fomes japonica, milk veteh, angelica, and the like and provides an effective method for controlling the quality of the polyoses and the products thereof.

The invention discloses a rare earth metal-organic frame with a fluorescent recognition function. The chemical formula is {[Tb2(TATAB)2)].4H2O.6DMF}n, wherein the TATAB in the formula is 4,4',4''-s-triazine-1,3,5-tri-para aminobenzoic acid; each metal framework structure elementary unit comprises two crystallographically independent Tb<3+> ions and two TATAB ligands, and the two Tb<3+> ions are connected into a dual-core elementary unit [Tb2(CO2)4] through six oxygen atoms on the two TATAB ligands; the dual-core units are connected into a one-dimensional Tb-carboxyl chain through the ligands, and extend towards four directions respectively through rigid benzene ring carboxyl on TATAB to form a three-dimensional porous network frame. The rare earth metal-organic frame has the advantages that the material synthesis process is simple, the crystal purity is high, the structure is novel, the stability in organic solvent is high, and formaldehyde and benzaldehyde can be recognized at the same time.

The invention relates to a cigarette mainstream smoke on-line analysis device and a cigarette mainstream smoke on-line analysis method. The device comprises a smoking machine and an atmospheric pressure chemical ionization tandem mass spectrometer. The on-line analysis method comprises the steps that: when the cigarette is smoked, mainstream smoke is collected into a mainstream smoke collection bottle; the smoke sample is directly introduced into the atmospheric pressure chemical ionization tandem mass spectrometer through a feeding valve, and is subjected to fast analysis. Compared with a traditional cigarette mainstream smoke analysis method, the smoking machine and the sample collection and introduction device have the advantages of simple structure and convenient operation. The sampling bottle of the smoking machine is connected to an ion source of the mass spectrometer through a capillary, such that sample direct introduction can be realized. Only a few seconds are needed from cigarette smoking to feeding and analysis. The sensitivity is high, and repeatability is good. The method and the device are suitable for on-line analysis of organic compounds in single-suction and suction-by-suction cigarette mainstream smoke.

The invention discloses a Cu/ZnO catalyst, a preparation method thereof and application thereof to CO2 chemical conversion and belongs to the fields of catalysis and greenhouse gas CO2 emission reduction. The preparation method of the Cu/ZnO catalyst includes the steps that soluble zinc salt and hexamethylene tetramine are dissolved in an ethylene glycol aqueous solution; under the inert atmosphere, a ZnO carrier is synthesized through reaction in a microwave reactor at the power of 200-300 W; by means of a deposition precipitation method, active metal copper is supported on the synthesized ZnO carrier. The synthesized ZnO carrier has uniform flowerlike or nanorod morphology, and the Cu loading is 5-15 wt%. The catalyst represents high activity and stability in the reaction of synthesizing low-carbon alcohol through CO2 catalytic conversion. The synthesized catalyst has the advantages of being simple in technology, low in cost, high in catalytic performance and the like, and accords with the development trend of green chemical engineering. Besides, the catalyst has wide application prospects in the field of synthesizing important chemicals through CO2 chemical conversion.

The invention discloses a synthetic method of a parecoxib sodium impurity, namely N-[[3-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]propanamide, belonging to the technical field of chemical pharmacy; the parecoxib sodium impurity is obtained by carrying out sulfonation reaction, amination reaction and propionylation reaction by taking 5-methyl-3,4-diphenyl isoxazole as the raw material; the synthesized high-purity parecoxib sodium impurity can be used as an impurity standard sample in detection and analysis of parecoxib sodium finished products; therefore, the accurate positioning property and the qualitative diagnosis to impurities in detection and analysis of parecoxib sodium finished products are increased; control of the impurity is strengthened easily, so that the quality of the parecoxib sodium finished products is increased; the synthetic method disclosed by the invention is cheap and available in raw materials and simple to operate; the yield of the prepared parecoxib sodium impurity is 85+/-5%; and the HPLC (High Performance Liquid Chromatography) purity is more than or equal to 98%.

The invention provides a method for monitoring the gas types and concentrations by utilizing an array gas sensor. The method comprises the steps of: acquiring the resistance value of the array gas sensor in real time, and calculating the resistance change rates of multifunctional sensing components within a pre-set time period in real time; pre-judging whether target gas exists in current air or not; if not, judging whether m-x resistance change rates in m resistance change rates of the continuous multifunctional sensing components are greater than the first resistance change rate threshold theta<r1> or not, and if so, determining that the target gas exists in the current air; extracting the related characteristics of the resistance value detected by the array gas sensor, and forming a characteristic vector; identifying the characteristic vector by adopting a classifier, so that the type of the target gas is identified; according to the type of the target gas, calculating the first response value of the target single sensing component responding to the target gas at this time; and, according to a response value-concentration formula and the first response value, obtaining the concentration value of the target gas by calculation.

The invention relates to a full-ion monitoring and quantifying method based on a second-level mass spectrum. The method comprises a mass spectrum data collection step and a mass spectrum data processing step, wherein the mass spectrum data collection step comprises the step of combining a peptide fragment liquid phase classification technique with a mass spectrum gas phase classification technique, and collecting mass spectrum data by virtue of a non-dynamic exclusion type data dependence mass spectrum scanning mode, so as to realize full collection of mass spectra of fragment ions of all peptide fragments; and the mass spectrum data processing step comprises the step of after the collection of the mass spectrum data, making comparison on intensities of mass spectrum peaks of second-level spectrum ions of multiple labeled peptide fragments of the same peptide fragment, so as to realize the quantitative analysis of proteins among different samples. The method has the advantages of high detection sensitivity, low noise disturbance, good repeatability and high quantifying accuracy and further has wide application prospects in the large-scale qualitative and quantitative analysis of proteomics.

The invention aims at providing an electric power industry control system network management method based on a multi-dimensional virtual link, wherein the electric power industry control system network management method based on the multi-dimensional virtual link can effectively promote the network management level of an electric power industry control system. According to the network management characteristics of the electric power industry control system, a network management model based on the multi-dimensional virtual link is established by means of the abstract electric power industry control system service logical relation, and accordingly the network management level of the electric power industry control system is promoted comprehensively and systematically. The electric power industry control system network management method based on the multi-dimensional virtual link can be applied to the network management field.

The invention discloses a detection method of carbon tetrafluoride in a column type circuit breaker for a 1100kV filter. The detection method comprises the following steps: 1) using gas in the columntype circuit breaker for the 1100kV filter as a to-be-detected sample; injecting the to-be-detected sample into a gas chromatography-quadrupole time-of-flight tandem gas chromatograph-mass spectrometer to obtain the peak area of CF4 of the to-be-detected sample in an ionic chromatogram; 2) comparing the peak area obtained in the step 1) with a standard curve of a CF4 standard product according toa chromatographic analysis external standard method so as to obtain content of the detected CF4 in the column-type circuit breaker for the 1100kV filter. The method is strong in pertinency, high in sensitivity and is suitable for detecting the content of the CF4 in the column-type circuit breaker for the 1100kV filter; moreover, the quantitative lower limit is up to 0.13 micro liter/liter.

The invention discloses a method for synthesizing a rivaroxaban process impurity, and belongs to the technical field of chemical pharmacy. The method comprises the following steps: preparing 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholin)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione (4) from 4-(4-aminophenyl)morpholin-3-one (2) and (S)-N-glycidyl phthalimide (3); hydrolyzing the compound (4), and salifying the hydrolyzed compound (4) to generate (S)-4-(4-((3-amino-2-hydroxypropyl)aminophenyl)morpholin-3-one hydrochloride (5); and preparing (S)-5-chloro-N-(3-(5-chlorothienyl-2-formamido)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)thiophene-2-carboxamide (1) from the compound (5) and 5-chlorothiophene-2-carbonyl chloride (6). The highly-pure rivaroxaban impurity synthesized in the inventioncan be used s an impurity standard product in the detection and analysis of a rivaroxaban finished product, so the accurate localization and qualitative diagnosis of the impurity in the detection andanalysis of the rivaroxaban finished product are improved, and the enhancement of the control of the impurity is benefited, thereby the quality of the rivaroxaban finished product is improved. The method has the advantages of cheap and easily available raw materials, and simplicity in operation, and allows the yield of the obtained product to be (70 +/- 5)% and the HPLC purity of the product to be equal to or more than 98%.

The invention provides a carboxylic acid derivatization reagent as well as a preparation method and application thereof, and belongs to the technical field of analytical chemistry. The carboxylic acidderivatization reagent is specifically ammonium N,N,N-trimethyl-2-(piperazine-1-yl)ethane-1-iodide, and the structural formula of the carboxylic acid derivatization reagent is shown in the specification. The carboxylic acid derivatization reagent can be used as a derivatization reagent for carboxylic acid metabolite spectrum detection, and has a good mass spectrum sensitization effect, so that the carboxylic acid derivatization reagent has good practical popularization and application values.

The invention discloses a chromatographic column for analyzing multiple pesticide residues in a complex matrix and an applying method of the chromatographic column, and belongs to the field of monitoring of pesticide residues. The invention firstly discloses a chromatographic column for analyzing multiple pesticide residues in a complex matrix. The chromatographic column comprises a chromatographic column tube and filler, wherein the filler comprises the following components: anhydrous sodium sulfate, graphitized carbon and magnesium silicate. The invention further discloses a method for analyzing multiple pesticide residues in a complex matrix by applying the chromatographic column. The method comprises the following steps: (1) pre-leaching the chromatographic column by using a leaching solution; (2) adding an elution solvent in a to-be-purified sample for being dissolved to prepare a sample loading solution; (3) adding the sample loading solution in the chromatographic column treated by the step (1); and (4) eluting with the elution solvent, and collecting an eluant. The chromatographic column disclosed by the invention has a good purifying effect, is clear and distinguishable in a chromatographic peak of a target compound and high in sample recovery rate; the method is simple, convenient and rapid to operate.

The invention relates to a chromatographic analysis system which comprises a sample inlet, a sample introduction unit, a control unit, a chromatographic column and a detector and has the characteristic that the control unit is used for controlling the communication between the sample introduction unit and the sample inlet; a sample channel is arranged in the sample inlet; mobile phases carry a sample injected into the sample inlet to flow along the sample channel; and when the mobile phases pass through the sample channel at any moment, the mobile phases positioned on the cross section of the sample channel at the previous moment are all replaced. The invention also provides a chromatographic analysis method. The chromatographic analysis system and the chromatographic analysis method have the advantages of wide application scope, good separation, high sensitivity and the like.

The invention discloses a salfaprodil impurity B, and a preparation method and application thereof, belonging to the field of pharmaceutical and chemical industry. The structure of the salfaprodil impurity B is disclosed as Formula (I), and the salfaprodil impurity B is not reported in the documents currently. The preparation method of the salfaprodil impurity B comprises the following step: by using salfaprodil as the raw material, carrying out acidification and reduction to obtain the impurity B. The synthesis of the salfaprodil impurity B provides a qualified reference substance for quality control on salfaprodil.

The invention discloses a synthetic method for two bisoprolol fumarate process impurities, and belongs to the technical field of chemical medicines. The method provided by the invention takes p-hydroxybenzyl alcohol as a starting material, and the p-hydroxybenzyl alcohol reacts with 2-(2-chloroethoxy)propane to form (4-(2-isopropoxyethoxy)phenyl)methanol; the compound (4-(2-isopropoxyethoxy)phenyl)methanol reacts with oxirane-2-ylmethanol to form 2-((((4-(2-isopropoxyethoxy)benzyl)oxy)methyl)oxirane; and the compound 2-((((4-(2-isopropoxyethoxy)benzyl)oxy)methyl)oxirane reacts with isopropylamine (7) to form 1-((4-(2-isopropoxyethoxy)benzyl)oxy)-3-(isopropylamino) propan-2-ol, the synthesized high-purity bisoprolol fumarate impurities can be used as impurity standard products in the detection analysis of a finished product of bisoprolol fumarate, thereby improving the accuracy positioning and qualitatively of impurities in bisoprolol fumarate finished-product detection analysis, facilitating reinforcement of the control of the impurities, and improving the quality of the finished product of the bisoprolol fumarate.

The invention discloses a stereo-selective synthesis method of a 6beta-hydroxymorphine derivative. The synthesis method comprises the following steps: (i) reducing a compound of a formula VI to a compound of a formula VII by sodium borohydride in a hydrophilic organic solvent in the presence of a catalytic amount of a C1-C4 alkanoic acid; and (ii) separating the compound of the formula VII obtained in the step (i) to obtain a compound of a formula VIII, wherein definitions of substituents in the formula VI, the formula VII and the formula VIII are detailed in the specification.

The invention relates to a non-contact type automobile electronic throttle pedal, which comprises a pedal arm, a shaft, an outer spring, an inner spring, a spring base seat, a bottom seat, a magnetic body partition board, a magnetic body, a chip, a wiring terminal and a connector, wherein the shaft is arranged in the center of the lower end of the pedal arm, one end of the outer spring and the inner spring is connected with the bottom of the pedal arm, the other end of the outer spring and the inner spring is arranged in the spring base seat, the spring base seat is arranged on the bottom seat, the magnetic body partition board is arranged at the front part of the lower end of the pedal arm, the magnetic body is riveted and connected inside the magnetic body partition board, the chip is welded on the bottom seat through ultrasonic waves, and the wiring terminal and the connector are welded on the chip. Compared with the prior art, the invention ensures the requirements of the precision and the stability of products, avoids the abrasion and other problems generated in the contact type automobile electronic throttle pedal, perfectly ensures the linear precision and the stability of the products, simultaneously ensures long service life and high precision of the products, and solves the problems of fuel oil waste and potential personnel safety hidden trouble caused by abrasion.

The invention discloses a piecewise two-point correlation self linear spectrum baseline correction method which comprises the following steps: step one, spectrum ranges which are non-sensitive to all target components or very low in sensitivity to all the target components as non sensitive areas are determined; step two, a transmittance spectra value mean value of each non sensitive area is respectively calculated, spectral line a which is most close to the corresponding transmittance spectra value mean value in each non sensitive area is determined, and a spectra value of the spectral line a is determined; step three, two adjacent spectral lines a are selected respectively, a baseline correction constant value and a correlation coefficient of a region between the two adjacent spectral lines a are calculated; baseline correction constant values and correlation coefficients of two end regions are consistent with that of an adjacent area. The piecewise two-point correlation self linear spectrum baseline correction method can improve the accuracy of spectrum qualitative and quantitative analysis, improves the recognition accuracy of the components in spectral analysis, saves time and labor, and reduces technical requirements of spectral operators or analysts.

The invention discloses a method for testing wear resistance of printing layers of tipping paper for cigarettes. The method includes: randomly cutting to-be-tested paper 18cm in length, fixing to the bottom of a 4-pound weight, and mounting the weight on a friction instrument, and fixing a white cardboard 21cm in length and 8cm in width onto a base of the friction instrument; adjusting parameters including the swing speed, the swing times and the like of the weight prior to conducting a friction test; taking the white cardboard as a blank to subject a colorimeter to origin calibration, and selecting three detection points on the white cardboard after completion of the friction test, wherein a center point of a friction portion of the white cardboard, a point about 3cm higher than the center point and a point about 3cm lower than the center point are selected as the three detection points; averaging detection data of the three detection points to obtain an average chromatic aberration value. The method for testing wear resistance of the printing layers of the tipping paper for the cigarettes is high in precision of qualitative comparison and quantitative analysis and has the advantages of short test time, convenience and quickness.

The invention puts forward VOCs (Volatile Organic Chemicals) detection equipment based on ion mobility spectrometry. The equipment comprises one or more acquisition devices, a sample pretreatment device for dust removal and water removal, a VOCs detector and a controller, wherein the VOCs detector comprises an ion mobility spectrometry; a dimethyl silicon film and/or a polypropylene film are/is arranged at a sample gas inlet of the ion mobility spectrometry; each sampling device is respectively communicated with a sample treatment device through a pipeline; an electromagnetic valve is arrangedon the pipeline between each sampling device and the sample pretreatment device; the sample pretreatment device is communicated with the sample gas inlet of the ion mobility spectrometry; and the controller respectively controls the acquisition devices, the electromagnetic valve, the sample pretreatment device and the ion mobility spectrometry. The equipment can effectively remove the interference of dust, moisture and ammonia molecules in the sample gas, improve the resolution of the ion mobility spectrometry, and quickly, qualitatively and quantitatively analyze VOCS at different positions,so as to make a purification treatment scheme in a targeted manner.