A kind of doxylamine succinate hydrochloride pyridoxine enteric-coated tablet medicinal composition and preparation method thereof

Abstract

The invention provides a compound doxylamine succinate-pyridoxine hydrochloride enteric-coated tablet pharmaceutical composition and a preparation method thereof. The composition comprises a tablet core containing doxylamine succinate and pyridoxine hydrochloride, an isolation coating, an enteric coating and other medicinal auxiliary materials. The preparation method has simple processes. The pharmaceutical composition has good stability, is insoluble in the stomach and can be fast released in the intestine so that the problem that the existing pharmaceutical composition has a reduced release rate when entering into an intra-intestinal neutral environment from a gastric acid environment.

Description

technical field

[0001] The invention relates to a doxylamine succinate hydrochloride pyridoxine enteric-coated tablet pharmaceutical composition and a preparation method thereof, belonging to the technical field of medicines. Background technique

[0002] Morning sickness is a natural reaction during pregnancy. The main symptoms are weakness, depression, dizziness, nausea, nausea, poor appetite, sensitivity or strong reaction to peculiar smell, especially in the early morning or when you just wake up. These symptoms generally occur around the fifth week of pregnancy. After the sixteenth week, most people's morning sickness will gradually reduce until it disappears naturally, but there are also a few pregnant women who have morning sickness throughout pregnancy, which is quite painful. Morning sickness is not only detrimental to the recuperation of pregnant women, but also because most people's appetite is affected during pregnancy, and the nutrition of the fetus comes from t...

Images