Anti-free-radical composition and preparation method and application thereof

Abstract

The invention discloses an anti-free-radical composition and a preparation method and application thereof, and belongs to the field of cigarette additives and application thereof. The composition is prepared from the following raw materials in parts by weight: 3 to 10 parts of cryptoxanthin, 4.5 to 20 parts of curcumin, 0.2 to 2 parts of an antioxidant, 0.4 to 1.2 parts of an excipient, 8 to 15 parts of vegetable oil and 72 to 89 parts of a water-soluble polymer. The method comprises the following steps: 1) mixing the cryptoxanthin, the curcumin, the antioxidant, the excipient, the vegetable oil and the water-soluble polymer in parts by weight to obtain a mixture; and (2) adding the mixture into a double-screw extruder, and performing extruding to obtain a powder, namely the anti-free-radical composition. The invention discloses the application of the anti-free-radical composition in the field of preparation of electronic cigarette additives, and the anti-free-radical composition has agood effect of scavenging free radicals, and is easy to atomize, stable in character and free from toxic or side effect.

Description

technical field [0001] An anti-free radical composition and its preparation method and application belong to the field of cigarette additives and its application. Background technique [0002] E-cigarettes are a product that atomizes e-cigarette liquid through an atomizer to form smoke for users to use instead of traditional cigarettes. Among them, the e-cigarette liquid is mainly made of tobacco leaf extract, adding additives, and mixing to make different flavors. Cigarettes made of traditional shredded tobacco are less harmful to the human body when burned, and electronic cigarettes are effective, so they are widely used. [0003] The applicant discovers the following issues through research: [0004] First, in the prior art, tobacco leaf extracts are mostly obtained from tobacco leaves through solvent extraction, and tobacco leaf extracts contain nicotine, which still damages free radicals in the human body. [0005] At present, there are not many studies on free radic...

AI Technical Summary

Problems solved by technology

Moreover, nicotine itself has direct damage to the human cardiovascular system, resulting in increased heart rate, increased blood pressure, coronary artery constriction, and damage to the vascular endothelium. It also produces nicotine poisoning and increases the risk of lung cancer. A study in the United States found that nicotine in tobacco may be one of the factors leading to the metastasis of lung cancer

In the prior art, there is a design for anti-free radical effect by adding antioxidants, but the anti-free radical effect is not ideal

[0006] Second, although there are formula designs for researching free radical scavengers in the prior art, they are not suitable for use as electronic cigarette additives

1. Electronic cigarettes are atomized through an atomizer. Although they are breathed into the lungs for absorption, the existing free radical scavengers have poor solubility and fluidity in water, resulting in unsatisfactory atomization effects and cannot be used in the field of electronic cigarettes; 2. 1. Most of the existing free radical scavengers have side effects and low tolerance doses, and users who are more addicted to smoking will frequently use e-cigarettes many times a day. Ingested in large quantities, high doses of existing free radical scavengers have relatively large side effects

3. In the prior art, there are many anti-oxidation and free-scavenging ingredients, but most of them have the disadvantages of poor taste and unstable properties, such as vitamin C taste sour and unstable, astaxanthin is easily decomposed when exposed to light, anthocyanin The taste is both bitter and astringent, which makes most of the existing free radical scavenging compositions unsuitable for use in the field of electronic cigarette additives