3 results about "Increased heart rate" patented technology

This invention discloses a traditional Chinese medicine composition for assisting in the improvement of hand-foot-mouth disease in infants and young children, belonging to the field of traditional Chinese medicine technology. The composition consists of eight medicinal herbs: lotus leaf, coix seed, angelica dahurica, kudzu root, platycodon root, agastache rugosa, cimicifuga rhizome, and dandelion, with a defined optimal medicinal ratio. Based on the seasonal differences in the pathogenesis of hand-foot-mouth disease, this invention targets the core pathologies of winter (cold congestion of microvessels, water and sodium retention, and internal heat generation) and spring and summer (hypothalamic sympathetic activation, increased heart rate, and visceral heat overload). It also addresses the technical deficiencies of clinical Western medicine, cold-natured traditional Chinese medicine, calamine lotion, and diuretics, such as vasoconstriction, kidney damage, central nervous system disorders, increased skin exudation, and rebound water retention. This invention employs a combination of warming and cooling herbs, regulating the ascending and descending functions, and promoting diuresis and protecting the body's vital energy. The synergistic effects of these herbs can dilate spasmodic microvessels, improve renal perfusion, stabilize abnormal heart rates, stabilize the hypothalamic center, and assist in antagonizing enteroviruses. By targeting and reducing abnormal permeability of skin capillaries with Angelica dahurica and Platycodon grandiflorus, it reduces blood extravasation and inhibits the formation and exudation of herpes from the root cause. This invention has mild medicinal properties, is suitable for all seasons, and has high safety. It can effectively improve symptoms of hand-foot-mouth disease such as fever, herpes, irritability, and cold extremities, reduce the risk of severe illness, antagonize the toxic side effects of commonly used clinical drugs, and is suitable for the delicate constitution of infants and young children, possessing good prospects for clinical application and promotion.

The application belongs to the technical field of medicine, and particularly relates to application of acacetin or 6-hydroxyflavone in preparation of anti-angina pectoris drugs, and aims to solve the problems of adverse reactions such as blood pressure drop, reflex tachycardia and the like caused by non-selective vasodilation of existing anti-angina pectoris drugs, wherein the drug improves myocardial blood supply by selectively dilating coronary vessels of the heart, wherein acacetin dilates coronary vessels of the heart by inhibiting cardiac coronary vessel myosin light chain kinase and activating myosin light chain phosphatase, and 6-hydroxyflavone dilates coronary vessels of the heart by inhibiting protein kinase C and enhancing myosin light chain phosphatase activity; and the acacetin or 6-hydroxyflavone significantly reduces the symptoms of myocardial ischemia of rats caused by isopropyl adrenaline, improves characteristic ECG abnormal changes of angina pectoris, does not affect heart rate and systemic blood pressure, and is safer, thereby providing a potential drug selection for anti-angina pectoris treatment.

This invention discloses a traditional Chinese medicine composition for improving acne, consisting of Platycodon grandiflorus, Citronella rotundus, Taraxacum mongolicum, Angelica dahurica, Angelica sinensis, fermented soybean, Prunus persica, and Saffron. Studies have shown that anti-inflammatory Western medicines, heat-clearing and cooling traditional Chinese medicines, and topical anesthetic acne-removing drugs can constrict visceral capillaries or inhibit skin heat dissipation nerves, causing the body's heat to be unable to dissipate normally. This leads to increased heart rate and abnormally increased facial blood flow through hypothalamic regulation, compensating for heat loss and forming acne, while also increasing the burden on the heart. Long-term renal capillary constriction can also disrupt bone marrow hematopoietic homeostasis and increase the risk of leukemia. Platycodon grandiflorus, Citronella rotundus, Taraxacum mongolicum, Angelica sinensis, and Prunus persica can dilate visceral microvessels; Angelica dahurica bidirectionally regulates skin-visceral blood flow; fermented soybean stabilizes the body temperature center; and Saffron, within a safe dosage of 0.5-2 parts, bidirectionally regulates microvessels, achieving anti-inflammatory effects on the face, heat dissipation in the internal organs, and kidney protection and detoxification. This invention combines various drugs to dilate visceral blood vessels, stabilize central body temperature regulation, and suppress compensatory heart rate and facial congestion, thereby improving acne and acne scars from the root cause. It also protects the heart, kidneys, and blood system. The medicine is mild and can be taken for a long time. It is hormone-free, does not cause drug resistance, and is not prone to recurrence, making it suitable for industrial application.