9 results about "Increased heart rate" patented technology

Disclosed are methods and systems for treating epilepsy by stimulating a main trunk of a vagus nerve, or a left vagus nerve, when the patient has had no seizure or a seizure that is not characterized by cardiac changes such as an increase in heart rate, and stimulating a cardiac branch of a vagus nerve, or a right vagus nerve, when the patient has had a seizure characterized by cardiac changes such as a heart rate increase.

This invention discloses a traditional Chinese medicine composition for assisting in the improvement of hand-foot-mouth disease in infants and young children, belonging to the field of traditional Chinese medicine technology. The composition consists of eight medicinal herbs: lotus leaf, coix seed, angelica dahurica, kudzu root, platycodon root, agastache rugosa, cimicifuga rhizome, and dandelion, with a defined optimal medicinal ratio. Based on the seasonal differences in the pathogenesis of hand-foot-mouth disease, this invention targets the core pathologies of winter (cold congestion of microvessels, water and sodium retention, and internal heat generation) and spring and summer (hypothalamic sympathetic activation, increased heart rate, and visceral heat overload). It also addresses the technical deficiencies of clinical Western medicine, cold-natured traditional Chinese medicine, calamine lotion, and diuretics, such as vasoconstriction, kidney damage, central nervous system disorders, increased skin exudation, and rebound water retention. This invention employs a combination of warming and cooling herbs, regulating the ascending and descending functions, and promoting diuresis and protecting the body's vital energy. The synergistic effects of these herbs can dilate spasmodic microvessels, improve renal perfusion, stabilize abnormal heart rates, stabilize the hypothalamic center, and assist in antagonizing enteroviruses. By targeting and reducing abnormal permeability of skin capillaries with Angelica dahurica and Platycodon grandiflorus, it reduces blood extravasation and inhibits the formation and exudation of herpes from the root cause. This invention has mild medicinal properties, is suitable for all seasons, and has high safety. It can effectively improve symptoms of hand-foot-mouth disease such as fever, herpes, irritability, and cold extremities, reduce the risk of severe illness, antagonize the toxic side effects of commonly used clinical drugs, and is suitable for the delicate constitution of infants and young children, possessing good prospects for clinical application and promotion.

To lower systolic blood pressure while having little or no effect on diastolic blood pressure, or to lower systolic blood pressure while still increasing diastolic blood pressure, a system and method for controlling blood pressure using the difference in the effects on systolic and diastolic blood pressure are provided. **Solution**: A controller configured to perform transmission of stimulation pulses of one or more stimulation patterns to at least one heart chamber of a patient's heart is provided. In a first operating mode, both the patient's systolic and diastolic blood pressures are lowered by a first stimulation pattern. In a second operating mode, the systolic blood pressure of the patient is lowered while controlling the diastolic blood pressure so as to reduce the difference between the systolic and diastolic blood pressures by a second stimulation pattern. In particular, the second stimulation pattern can combine a stimulation pattern that lowers blood pressure with a stimulation that increases heart rate to lower the systolic blood pressure while limiting the effect on the diastolic blood pressure to a level that does not prevent the achievement of a therapeutically effective reduction in pulse pressure.

The application belongs to the technical field of medicine, and particularly relates to application of acacetin or 6-hydroxyflavone in preparation of anti-angina pectoris drugs, and aims to solve the problems of adverse reactions such as blood pressure drop, reflex tachycardia and the like caused by non-selective vasodilation of existing anti-angina pectoris drugs, wherein the drug improves myocardial blood supply by selectively dilating coronary vessels of the heart, wherein acacetin dilates coronary vessels of the heart by inhibiting cardiac coronary vessel myosin light chain kinase and activating myosin light chain phosphatase, and 6-hydroxyflavone dilates coronary vessels of the heart by inhibiting protein kinase C and enhancing myosin light chain phosphatase activity; and the acacetin or 6-hydroxyflavone significantly reduces the symptoms of myocardial ischemia of rats caused by isopropyl adrenaline, improves characteristic ECG abnormal changes of angina pectoris, does not affect heart rate and systemic blood pressure, and is safer, thereby providing a potential drug selection for anti-angina pectoris treatment.

A system comprising a toilet seat and an evaluation unit (20), wherein a sensor system (10) for detecting a plurality of vital parameters is integrated into the toilet seat, and the toilet seat has a technology box (4) in which a control unit for controlling the sensor system (10) and for the individualized detection of the measurement data detected by the sensor system (10), in particular vital parameters, and a communication interface for receiving and transmitting data are accommodated, wherein the communication interface is in data communication with the evaluation unit (20), which is designed with a diagnostic unit configured to evaluate the detected vital parameters on the basis of databases stored in the evaluation unit (20) or connected via a further communication interface, and to output corresponding information or recommendations to the user or a unit operating the toilet seat (1) via an output interface, characterized in that the sensors (10) sensors for recording an ECG, the Body temperature, blood oxygen saturation and pulse rate, and wherein the evaluation unit (20) is designed with an artificial intelligence (AI) which is designed to output a finding according to a class based on the recorded measurement data, The AI ​​issues a Class 1 finding if a normal ECG, normal oxygen saturation, normal body temperature, normal weight and normal BMI are detected, the AI ​​issues a Class 2 finding if an increased heart rate, reduced oxygen saturation, elevated temperature, increased weight and / or abnormal BMI is detected, the AI ​​issues a Class 3 finding if a cardiac arrhythmia or atrial fibrillation, or low oxygen saturation, high temperature, significantly excessive weight or BMI is detected, The AI ​​is designed to detect a certain trend by comparing it with the user's existing data, indicating an improvement or deterioration in vital signs, and the AI ​​can determine whether a medication is working.

A method of modulating blood glucose levels and / or treating diabetes is disclosed. The method comprises the step of administering a fusion peptide of a GLP-1 peptide and an Fc region. The Fc region is a hybrid Fc region comprising a hinge region, a CH2 domain and a CH3 domain in a direction from N-terminus to C-terminus wherein the hinge region comprises a human IgD hinge region, the CH2 domain comprises part of amino acid residues of the CH2 domain of human IgD and human IgG4, and the CH3 domain comprises part of amino acid residues of the CH3 domain of human IgG4 and is glycosylated in the IgD hinge region. The fusion peptides exhibit reduced side effects, such as emesis, nausea and / or increased heart rate.

The invention discloses a data processing method and system based on virtual reality, and the method comprises the steps: analyzing the influence of expression information and muscle signals of a patient on training actions, adjusting a virtual training model according to an analysis result, analyzing the training amount of the patient under the adjusted training actions, and adjusting a rehabilitation training scheme of the patient. Whether the training action is excessive or not is judged by analyzing the facial expression change of the patient during the training action, for example, the conditions of eyebrow wrinkling, mouth micro-tension, heart rate acceleration and the like possibly caused by pain of the patient, then the expression change of the patient in the action process is analyzed, the limit action range of the virtual training model is determined, and the virtual training model is adjusted. The virtual training model meets the training requirements, the situation that the rehabilitation training effect is poor due to overtraining of the patient is avoided, then the better training effect is achieved, and the method has the advantages of being high in accuracy and good in rehabilitation training effect.

The invention relates to application of ITSA1 in preparation of a medicine for treating or preventing cardiac remodeling or hypertension, and belongs to the technical field of prevention of cardiovascular diseases. The method comprises the following steps: constructing a chronic intermittent hypoxia (CIH) animal model by using a mouse, performing blood pressure measurement 2 weeks, 4 weeks and 8 weeks before and during construction of the animal model, and performing cardiac ultrasound, Masson staining, alpha-SMA immunohistochemistry, WGA staining and the like after the model is finished. Experimental results show that the ITSA1 relieves blood pressure rise, accelerated heart rate, cardiac function, myocardial fibrosis and myocardial cell hypertrophy caused by chronic intermittent hypoxia. Experiments prove that the ITSA1 can effectively relieve blood pressure rise and cardiac remodeling caused by chronic intermittent hypoxia, and a foundation is laid for widening the clinical application range of the ITSA1.

This invention discloses a traditional Chinese medicine composition for improving acne, consisting of Platycodon grandiflorus, Citronella rotundus, Taraxacum mongolicum, Angelica dahurica, Angelica sinensis, fermented soybean, Prunus persica, and Saffron. Studies have shown that anti-inflammatory Western medicines, heat-clearing and cooling traditional Chinese medicines, and topical anesthetic acne-removing drugs can constrict visceral capillaries or inhibit skin heat dissipation nerves, causing the body's heat to be unable to dissipate normally. This leads to increased heart rate and abnormally increased facial blood flow through hypothalamic regulation, compensating for heat loss and forming acne, while also increasing the burden on the heart. Long-term renal capillary constriction can also disrupt bone marrow hematopoietic homeostasis and increase the risk of leukemia. Platycodon grandiflorus, Citronella rotundus, Taraxacum mongolicum, Angelica sinensis, and Prunus persica can dilate visceral microvessels; Angelica dahurica bidirectionally regulates skin-visceral blood flow; fermented soybean stabilizes the body temperature center; and Saffron, within a safe dosage of 0.5-2 parts, bidirectionally regulates microvessels, achieving anti-inflammatory effects on the face, heat dissipation in the internal organs, and kidney protection and detoxification. This invention combines various drugs to dilate visceral blood vessels, stabilize central body temperature regulation, and suppress compensatory heart rate and facial congestion, thereby improving acne and acne scars from the root cause. It also protects the heart, kidneys, and blood system. The medicine is mild and can be taken for a long time. It is hormone-free, does not cause drug resistance, and is not prone to recurrence, making it suitable for industrial application.