The application provides a
clinical marker screening method and
system after metabolic response
typing and application. Specifically, according to the change of metabolic indexes of
normal weight people and
overweight / obese people before and after meals, three clusters based on
respiratory quotient (RQ) are found; the fasting
fat oxidation capacity, postprandial metabolic response and postprandial blood glucose response of people belonging to different clusters also have different dynamic
change patterns. In addition, key biomarkers distinguishing the three clusters are also found; the prediction model constructed by using the key biomarkers can accurately divide the subjects into three RQ clusters and can be used for predicting the results of
weight loss intervention and life intervention guidance. The
system constructed according to the clinical markers of the application has high sensitivity and accuracy, the indexes used are easy to obtain, and has good clinical application prospect.