The invention provides a metformin anti-aging skin care product, which comprises metformin, other active ingredients, conventional raw materials, auxiliary materials and the like, and can be preparedinto paste, emulsion, cream, a gel, spray, milk, lotion and other forms through dissolving, heating, stirring, cooling and other process methods. According to the invention, the anti-aging drug metformin and other active ingredients in the skin care product can directly act on the surface of skin, or permeate into local or whole-body blood circulation through skin so as to achieve the effect of transdermal drug delivery, and can be used for skin aging resistance, body aging resistance and treatment of various diseases such as type 2 diabetes mellitus, polycystic ovarian syndrome, tumors and other like; with the metformin anti-aging skin care product, the damage to the oral metformin medicine in the gastrointestinal tract, the possible first-pass effect of live and the gastrointestinal inactivation are avoided, the damage to liver and kidney is reduced, toxic and side effects are reduced, and a new method and way are provided for safely and effectively expanding the range of users; andthe anti-skin aging or anti-body aging and the medication method are simple, convenient, easy and acceptable.