2 results about "Systemic blood" patented technology

This invention provides a topical finasteride formulation and its preparation method, belonging to the field of pharmaceutical formulation technology. The topical finasteride formulation provided by this invention is a topical dosage form, comprising finasteride and excipients; after scalp administration, the concentration in hair follicles and the epidermis is 999-5021 pg / mL, and the systemic blood concentration is 17.1-178.9 pg / mL; the systemic blood concentration is 1-10% of that of oral finasteride formulations. The method involves preparing finasteride and excipients, followed by steps of dissolving / preparing the matrix, fine filtration / homogenization, and filling to obtain finasteride topical formulations of different dosage forms. This invention effectively solves the shortcomings of existing finasteride formulations, such as high systemic absorption, high risk of adverse reactions, and difficulty in industrializing the process, making it suitable for large-scale clinical application in androgenetic alopecia, combining efficacy and safety.

The application relates to a post-illness limb function recovery training device, which comprises a chassis, a cushion fixed at the upper end of the chassis and a fixing frame fixed at one end of the chassis, two sliding frames are fixed at the upper end of the fixing frame, and the right lower end of the sliding frame is fixedly connected with the chassis. The device can move forward and backward through the soft foot cover and the horizontal rod after operation, and can perform lower limb training such as leg stretching and knee bending, improve the knee joint activity, prevent postoperative joint stiffness, and can separate and approach the two soft foot covers, open the two feet from the close to the two sides, and then recover the close, improve the hip joint activity and the lower limb stability, further improve the postoperative lower limb rehabilitation training effect, and in addition, during the lower limb training, the backrest can be slightly rotated, the upper body can be moderately moved during the lower limb training, the whole body coordination is enhanced, the whole body blood circulation is promoted, and the risk of local blood stasis of the upper body is reduced.