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48 results about "Blood group antibodies" patented technology
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Blood group antibodies in the serum are the clinically significant antibodies, which can specially identify antigens locate on the surfaces of red cells of another blood group, typically for transfusion purposes. As we all know, if mixing incompatible blood groups, blood clumping or agglutination will occur.
Human erythrocyte membrane antigen coated microsphere and application thereof
InactiveCN101957366AMaintain and preserve antigenic activityLong validity periodBiological testingAntiendomysial antibodiesMicrosphere
The invention provides a method for preserving the activity of a human cell membrane blood group antigen, which comprises the steps of: preparing an erythrocyte membrane blood group antigen extract, and then coating the prepared erythrocyte membrane blood group antigen on a solid microsphere so as to replace a fresh erythrocyte to be used for detecting a blood group antibody in a sample.
Owner:INTEC PROD INC
Erythrocyte membrane antigen magnetic ball kit and applications on blood group antibody detection
InactiveCN101387648AExtended shelf lifeEasy to storeBiological testingErythrocyte membraneMagnetic bead
A red cell membrane antigen magnetic bead kit and an application in blood type antibody test belong to the biological technical field, for using red cell membrane antigen magnetic beads to prepare a kit and provide the application in blood type antibody test. The kit comprises red cell membrane antigen magnetic beads, a U-shaped reaction plate of 96 holes and a red cell membrane antigen magnetic bead diluent. The invention has the advantages that the red cell membrane antigen magnetic beads have long storage period, thus is beneficial for the storage of red cell rare antigens.
Owner:长春博德生物技术有限责任公司
Test strip for specifically measuring IgM, IgG and IgA blood group antibodies
The invention belongs to the field of biological medicines and discloses an immunochromatography test paper technology, which is used for specifically measuring the negative, positive and titer of IgM, IgG and IgA blood group antibodies in blood or body fluid or tissue fluid or secretion of people. The technology comprises the following steps: (1) preparing a sample filter membrane and a sample pad; (2) preparing a tracer and a tracing pad; (3) preparing a fiber membrane detection area and a quality control area; (4) labeling a test strip; (5) assembling the test strip; (6) injecting a sample and detecting; and (7) reading a result. The test strip can be used for measuring IgM anti-A and anti-B antibody titer, monitoring implantation of bone marrow transplantation and measuring the titer of immune IgG anti-A and anti-B antibodies of individuals, particularly prenatal pregnant women and newborns, the reverse typing of blood groups can be accurately judged by specifically measuring the IgM anti-A and anti-B antibodies, and the reverse typing of the blood group of an individual can be judged through saliva without blood sampling by specifically measuring IgA anti-A and anti-B antibodies in secretion.
Owner:邵超鹏
Method for detecting Miltenberger blood group antibody
InactiveCN104360087AAchieving Simultaneous DetectionEnsure safetyBiological testingFluorescenceMagnetic bead
The invention discloses a method for detecting a Miltenberger blood group antibody. The method comprises the steps of coupling nano magnetic beads with avidin to form avidin magnetic beads; coupling the avidin magnetic beads with a multipeptide antigen with a biotin-modified tail end, and closing non-coupled sites to obtain immune magnetic beads; uniformly mixing the immune magnetic beads with a detection sample, then performing incubation and washing, adding fluorescence labeled second antibody or enzyme-labeled second antibody, performing incubation and washing, and measuring a result. In the mode, the method for detecting the Miltenberger blood group antibody based on nano magnetic bead immunoassay is low in operation difficulty and is simple and convenient to operate, can be used for simultaneously detecting complete antibodies and incomplete antibodies; the detection process is short in time, and the result is easy to judge; automation is easily realized, and the detection result is accurate; in combination with a detector, semi-quantitative or quantitative detection can be realized; clinical safe, effective and scientific blood transfusion can be guaranteed.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
Method and detection strip for rapidly detecting human blood group antibodies
InactiveCN101957370AEasy to storeEasy and convenientBiological testingImmune complex formationImmune complex deposition
The invention relates to a method for the immunodetection of human blood group antibodies, particularly relating to a method and a used detection strip for rapidly detecting human blood group antibodies. The method comprises the following steps: a blood group antigen is precoated on a solid-phase carrier; the blood group antigen with a signal mark is fixed on a fiber mat adhered on one end of the carrier; and a sample is added dropwise, if the sample to be detected contains an antibody which can be combined with the blood group antigen, a macroscopic immune complex can be observed on the solid-phase carrier, and otherwise, the macroscopic immune complex is not formed, thus the blood group antibody in the sample is detected.
Owner:INTEC PROD INC
Method of implementing erythrocyte blood group antigen detection on haemocyte analysis instrument
InactiveCN1904618AImprove accuracyImprove work efficiencyBiological testingPre-DilutionErythrocyte parameter
The invention relates to a testing method for red corpuscle blood group antigen. It takes the processes of over pre-dilution, reacting, and testing, respectively testing the reacting system formed by tested red corpuscle and blood group antibody that is already known and the red corpuscle parameter of the comparing system constructed by the tested red corpuscle suspension without blood group antibody, gaining the alteration of the two system red corpuscle parameters, taking comparison analysis to the restricted range to judge whether the agglutination reaction is occurred and indirectly testing whether the tested red corpuscle has the blood type antibody corresponding to that has already been known.
Owner:潘干华
Helicobacter pylori adhesin binding group antigen
A novel blood group antigen binding (BAB) adhesin protein was isolated and purified, whereby said protein or fractions thereof bind specifically to Helicobacter pylori fucosylated blood group antibodies. Said adhesin has a molecular weight of about 73.5 kDa and the N-terminal sequence for the adhesin and the corresponding DNA show homologies between different strains of H. pylori. Said adhesin and / or DNA is useful for diagnose and therapy and / or profylax directed against H. pylori induced infections, e.g. gastritis and acid peptic disease.
Owner:BOREN THOMAS +4
Novel Miltenberger blood group antibody detecting method
ActiveCN103344772ASolve the problem of shortage of sourcesSolve Simultaneous DetectionBiological testingFluorescenceMagnetization
The invention discloses a non-blood red cell dependent type Miltenberger blood group antibody detecting method. The detecting method comprises the following steps of: coupling sheep red blood cell subjected to hydroformylation and magnetization with polypeptide antigen containing a connecting chain to form an artificial screening cell; and uniformly mixing the artificial screening cell with a detecting sample for cultivating and washing, and measuring the result after adding fluorescence-labeled secondary antibody for cultivating and washing. By virtue of the way, the non-blood red cell dependent type Miltenberger blood group antibody detecting method provided by the invention is free of centrifuging for the washing due to the application of magnetic force, simple and convenient to operate, capable of realizing simultaneously detecting complete antibody and incomplete antibody, short in detecting process time consumption, easy to automate, accurate in detected result and capable of realizing semi-quantitative or quantitative detection by combining with a detecting apparatus, and the result is easy to judge. Besides, the detecting method can guarantee safe, efficient and scientific blood transfusion in clinic.
Owner:SUZHOU GUOKE MEDICAL TECH DEV CO LTD
Micropipe for blood grouping, one-piece ABO/RhD blood typing test card for blood grouping and preparation thereof
The invention discloses a micropipe for blood grouping, a one-piece ABO / RhD blood typing test card for blood grouping and a preparation thereof. The micropipe for blood grouping includes a gel, an antibody working solution and a serum separation gel from bottom to top in order. The antibody working solution comprises a blood group antibody and an antibody diluent which can make the blood group antibody maintain activity, and the serum separation gel having a specific gravity of 1.075-1.077 can perform thixotropy to turn the solid into the fluid in the presence of centrifugal force of 150 G to 300 G. The specific gravity of the antibody diluents is more than that of the serum separation gel and less than that of the erythrocyte. The one-piece ABO / RhD blood typing test card prepared by the micropipe can add peripheral blood directly to test, and has no need to test the blood sample after diluting the peripheral blood removed the erythrocyte by centrifuging. So that the sensitivity and specificity of the blood type test card are guaranteed, the operation steps of the traditional ABO / RhD blood typing test card are reduced, and the efficiency is improved.
Owner:SHENZHEN DAKEWE BIOENG
Kit for screening blood type irregular antibody
InactiveCN107202898AReduce missed detectionIncrease reaction strengthBiological testingK antigensRed blood cell
The invention provides a kit for screening a blood type irregular antibody, and belongs to the technical field of blood type antibody detection. The kit contains six parts of erythrocytes which are packaged separately and divided into three groups; the three groups of erythrocytes come from three persons respectively; at least two of D, C, c, E, e, s, Le, Fy and K antigens in the erythrocytes of each person are positive, and at least one of M, N, S, Le, JK, JK, Fy and P1 antigens is positive; antigen components of the three persons are complementary; each group of erythrocytes consists of two parts of independent erythrocytes packaged in the same specification; one part of erythrocytes is treated with bromelain, and the other part of erythrocytes is not treated with the bromelain; the concentrations of the six parts of erythrocytes in the kit are the same, and can be 1 to 5 percent. The kit is suitable for various blood type antibody detection methods in the prior art. By adopting the kit, the omission ratio of irregular antibodies is reduced, and the clinical blood transfusion risk is lowered.
Owner:SICHUAN MACCURA BIOTECH CO LTD
Blood type detection method based on membrane structure
InactiveCN104714034AShort detection timeThe result is objectiveBiological testingRed blood cellGroup A - blood
The present invention discloses a blood type detection method based on a membrane structure. According to the method, a filtration membrane allowing a single red blood cell to pass through is selected as a core material, blood type antibodies are bound to the filtration membrane, a water absorption material is surrounding the periphery of the filtration membrane, red blood cells with a certain concentration are added on the filtration membrane surface in a dropwise manner during detecting, rinsing is performed with a rinsing liquid, the red blood cells with no antigen-antibody binding exude along with the rinsing liquid, the red blood cells with the antigen-antibody binding are remained on the membrane surface so as to form the visible red clumps, and an operator can judge the result according to whether the red blood cells form the visible red clumps on the filtration membrane so as to determine the blood type of red blood cells. The method of the present invention has beneficial effects of short detection time and objective result.
Owner:TIANJIN DEXIANG BIOTECHNOLOGY CO LTD
Casset based on solid-phase type quick blood grouping and grouping method
PendingCN107907696AEasy to operateEasy to carryBiological testingErythrocyte membraneBlood group antigens
The invention relates to a casset based on solid-phase type quick blood grouping and a grouping method. The casset comprises a casset body, a sample groove, an antibody groove and a gold mark groove,wherein the sample groove is arranged in the middle part of the casset body; the antibody groove is arranged at one side of the sample groove; the gold mark groove is arranged at the other side of thesample groove; a monoclonal antibody is arranged in the antibody groove; a gold mark erythrocyte membrane antigen is arranged in the gold mark groove; an upper water absorbing paper is arranged between the sample groove and the antibody groove; a blood filtering membrane is arranged between the sample groove and the gold mark groove; a lower water absorbing paper is arranged under the blood filtering membrane. The casset has the advantages that the anti-A, anti-B and anti-D specific monoclonal antibodies are used as positive typing reagents of A, B and O blood groups, the A, B and O blood group antigens (gold mark antigens) marked with the specific erythrocyte membranes are used as reverse typing immune colloidal gold reagents, and the positive and reverse typing reagents are respectivelyarranged on the casset body; the operation is simple and quick, the carrying is convenient, the accuracy is high, the casset is suitable for the condition that the positive and reverse typing reagents of the blood group typing reagent are simultaneously placed into a blasting ball at mobile blood collection sites and during emergency blood transfusion.
Owner:BEIQIUEN INT PEACE HOSPITAL P L A
Immunochromatographic test strip for determining IgG anti-A and anti-B blood group antibodies of pregnant woman or human blood-group reverse typing
The invention relates to an immunochromatographic test strip for determining IgG anti-A and anti-B blood group antibodies of a pregnant woman or human blood-group reverse typing, and belongs to the technical field of biological medicines. The immunochromatographic test strip comprises a sample pad, a tracing pad, a cellulose membrane, an IgM blocking area, an IgG detecting area, a quality control area, a water absorbing pad and a supporting plate, wherein the supporting plate is positioned at the bottom part and is provided with the cellulose membrane, and the two ends of the cellulose membrane are respectively overlapped with the tracing pad and the water absorbing pad; and the sample pad is overlapped on the other end of the tracing pad. The immunochromatographic test strip has the advantages that the existence and the titer of human blood IgG-type anti-A and anti-B antibodies can be simply and rapidly determined in a specific manner, the traditional and current determination mode 'IgM inactivation, anti-human ball test and agglutination observation 'is replaced, the operation steps are greatly simplified, and the time consumed is shortened; and the immunochromatographic test strip also can be used for determining the reverse typing of human blood.
Owner:邵超鹏
Miltenberger blood group antibody detection test strip and detection method thereof
ActiveCN103389384ASimple and fast operationAchieve semi-quantitativeBiological testingFluorescenceBlood group antigens
The invention discloses a Miltenberger blood group antibody detection immunofluorescent chromatography test strip and a detection method thereof. The Miltenberger blood group antibody detection immunofluorescent chromatography test strip comprises a sample pad, a reaction film and an absorption pad which are in an ordinal overlap joint relationship. Two ends of the sample pad are provided with a first sample injection point and a second sample injection point. An inner quality control band and at least one antibody detection band are fixed to the reaction film. The detection method comprises the following steps of mixing a biotin-labelled polypeptide blood group antigen and a serum sample, adding the mixture into the sample pad, adding a fluorescent label second antibody into the sample pad, and carrying out detection by a fluorescence detector. The Miltenberger blood group antibody detection immunofluorescent chromatography test strip solves the problem that a simple and practical clinical conventional Miltenberger blood group antibody detection technology and a reagent are deficient, is used for assistant clinical diagnosis of Miltenberger blood group antibody-caused hemolytic disease of the newborn, and adverse effects of blood transfusion, and guarantees clinical safety, effectiveness and scientific blood transfusion.
Owner:SUZHOU GUOKE MEDICAL TECH DEV CO LTD
Opposing blood group antibodies, foodstuffs and dietary supplements
InactiveUS20070110830A1Good for healthBiocideAnimal repellantsEnvironmental healthDietary supplement
A dietary supplement comprises substances selected so as not to trigger a blood type antibody response. A method of improving health of an individual comprises determining an individual's blood antigenicity and providing to said individual ingestible substances non-reactive to said blood antigenicity.
Owner:DADAMO PETER J
Indirect Dot-ELISA (enzyme-linked immunosorbent assay) method and application of blood group antibody
InactiveCN103487590AImprove detection accuracyTo achieve the purpose of automatic operationBiological testingAssayCell membrane
The invention particularly discloses an indirect Dot-ELISA (enzyme-linked immunosorbent assay) method and application of a blood group antibody. The method comprises the following steps of fixing a nitrocellulose membrane on a 96-hole plate, then directly coating the nitrocellulose membrane with a red cell membrane, and reacting the red cell membrane with a to-be-detected antibody, so as to form an antigen-antibody compound through a second enzyme-labeled antibody. A Dot-ELISA plate can be prepared by utilizing a commercialized ELISA analysis instrument, so that the automatic operation can be achieved, and purposes of saving manpower, reducing personal errors and realizing high-throughput test are achieved. The Dot-enzyme-linked immunosorbent assay method for researching has the advantages that the efficiency is higher than 8 times of that of an indirect Coombs experiment; as the sensitivity is high, the detection accuracies of low-concentration and low-affinity antibodies can be increased, and a blood group detection method and the blood transfusion safety are further improved.
Owner:SOUTH CHINA AGRI UNIV
Automatic detection card and detection method of multi-blood group system
PendingCN111443211ASolving Clinical Testing ProblemsReduce workloadBiological testingType antigenBiology
The invention relates to an automatic detection card and detection method of a multi-blood group system. The automatic detection card comprises four parts, namely a sample addition layer, a reaction layer, a developing layer and an identification layer from top to bottom, wherein a sample addition hole is formed in the sample addition layer, a full-blood pad or a filter pad for filtering red bloodcells from full blood is arranged on the reaction layer, the bottom of the sample addition hole is connected with the full-blood pad or the filter pad, a tail end of the full-blood pad is connected with a plurality of antibody pads pre-coated with blood group antibodies, a tail end of the filter pad is connected with an antigen pad, pre-coated with a blood group antigen, through a delay pad, thereaction layer is separately provided with a quality control strip, a plurality of developing regions connected with tail end(s) of the antibody pads or the antigen pad are arranged on the developinglayer, and the identification layer is reversely connected with the developing layer. In the automatic detection card, blood group detection and a coding technology are combined, multiple blood groupscan be rapidly detected, automatic identification of multiple blood groups is achieved, artificial judgment errors are reduced, the detection efficiency is improved, special equipment is not needed,and rapid, accurate, automatic and portable detection of the blood groups is achieved.
Owner:CHONGQING UNIV
Therapeutic apparatus for treating maternal-fetal blood group incompatibility-type hemolytic disease
ActiveCN106267405AImprove bindingFacilitate perfusionOther blood circulation devicesHaemofiltrationSide effectImmune complex deposition
The invention relates to a therapeutic apparatus for treating a maternal-fetal blood group incompatibility-type hemolytic disease in the medical field. The therapeutic apparatus is characterized in that hemoglobin with toxic and side effects is removed from Rh-positive red blood cells through diapedesis by using PB lysate, but ghost cells which only absorb an Rh antibody and do not absorb other blood group antibodies are retained; together with an immunologically prepared anti-Rh antibody, the ghost cells are fixed to agarose with a special concentration according to a specific ratio; thereafter, the agarose is enwrapped by a cylindrical container made of a highly-biocompatible material so as to form gradually decreasing antibody valence, gradually increasing agarose concentration and uniform ghost cell distribution from a sample inlet end to a sample outlet end; near the sample outlet end, the agarose with the special concentration with gradually increasing concentration and gradually diminishing micropores can effectively intercept fragments formed after the red blood cells of a patient suffering from the hemolytic disease are destroyed, as well as macromolecular immune complexes combined with the fragments. The therapeutic apparatus provides a new toxic and side effect-free method for treating the maternal-fetal blood group incompatibility-type hemolytic disease, by which only pathogenic antibodies are removed, but plasma components are not removed.
Owner:ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV +1
Superparamagnetism functional particles, magnetized red blood cells and clinic application of superparamagnetism functional particles and magnetized red blood cells
The invention provides superparamagnetism functional particles and magnetized red blood cells. The surfaces of bacterial magnetic particles naturally carry rich -NH2 groups, the bacterial magnetic particles are modified through a certain chemical method so as to be activated and are in coupling connection with an anti-red blood cell GP (Glycoprotein) A monoclonal antibody, so that the superparamagnetism functional particles are prepared; before clinical blood group antibody detection, the superparamagnetism functional particles can be in incubation with red blood cells and can be quickly magnetized, then sample detection can be carried out, and centrifugal separation is replaced with magnetic separation during a detection process. A quick, simple and convenient testing method is provided for clinical application, and the superparamagnetism functional particles provided by the invention are especially beneficial for quick magnetization of the red blood cells and solid-liquid separation during a clinical blood group antibody detection process.
Owner:BEIJING GUO KE RONG ZHI BIOTECH CO LTD
A maternal and fetal blood group incompatibility immunosorbent therapeutic apparatus
InactiveCN109157694ASpeed can be adjustedEasy to transportOther blood circulation devicesMedical devicesExtracorporeal circulationCardiopulmonary bypass
A maternal-fetal blood group incompatibility immunosorbent therapy apparatus used in the medical field is characterized in that a blood separator and a plasma adsorber are connected through a circulation line to form a cardiopulmonary bypass adsorption device, wherein the blood separator is used for separating blood cells and plasma, as the separated plasma flows through and filters through the plasma adsorber, wherein the pathogenic antibody is adsorbed, the filtered plasma is combined with the separated blood cells and then re-enters a cardiopulmonary bypass adsorption device for circulatingadsorption to achieve the purpose of cleaning the pathogenic antibody, and the plasma adsorber is filled with a solid-phase carrier coated with blood group antigen or anti-blood group antibody with high to low gradient titer from an inlet to an outlet in a layered manner.
Owner:翁炳焕
Indirect Dot-ELISA (enzyme-linked immunosorbent assay) method and application of blood group antibody
InactiveCN103487590BImprove detection accuracyTo achieve the purpose of automatic operationBiological testingAssayImmune adsorption
Owner:SOUTH CHINA AGRI UNIV
Method and system for detecting Rh blood group antigen and application thereof
PendingCN113092793ALow costGet rid of dependenceBiological testingSolid phase adsorptionBlood group antibodies
Owner:JIANGYIN LIBO MEDICINE BIOTECH
Crossmatching blood samples
ActiveUS20170168075A1Reduce and preventMinimise any false positiveBiological material analysisBiological testingCrossmatching bloodPre transfusion
The present invention provides novel methods for the detection of antibodies, in particular, blood group antibodies. The methods of this invention may be applied to pre-transfusion blood compatibility testing for the detection of incompatibility between donor units (comprising donor red blood cells (erythrocytes)) and a recipient.
Owner:QBD QS IP
A kind of pool-checking red blood cell blood group irregular antibody detection kit based on solid-phase agglutination technology and preparation method
ActiveCN110174519BImprove coating efficiencyReduce testing costsBiological testingAgainst vector-borne diseasesLow ionic strengthFreeze-drying
Owner:广州血液中心
A kind of blood group antibody complex, preparation method
The present invention provides a blood group antibody complex whose structure is blood group antibody I-bridged secondary antibody-blood group antibody II. The present invention also provides a method for preparing the above-mentioned blood group antibody complex, comprising the following steps: S1, selecting two antibodies derived from the same biological species, namely blood group antibody I and blood group antibody II; S2, according to the blood group antibody Species sources of I and blood group antibody II, select a bridged secondary antibody that can specifically bind to blood group I and blood group antibody II at the same time; Mix evenly at a ratio of 1:1:1, and place at room temperature for 15-30 minutes to prepare a complex with the structure of blood group antibody I-bridged secondary antibody-blood group antibody II. The preparation method of the blood group antibody complex provided by the present invention can increase the specificity of the blood group antibody or improve the affinity and titer of the blood group antibody by utilizing the specific recognition between the antibody and its specific antibody, and the operation is simple and fast. Wide range of applications.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
Rapid detection kit for IgG blood group antibody titer
PendingCN111458524AGet rid of distractionsBright redBiological testingAntiendomysial antibodiesTiter
The invention discloses a rapid detection kit for IgG blood group antibody titer. The rapid detection kit comprises a standard red blood cell suspension, a flushing fluid and a detection test strip; the detection test strip comprises a sample adding part, a reaction part and a water absorption part which are sequentially arranged in a contact manner from the upstream side to the downstream side; the sample adding part is sequentially provided with a washing sample adding area, an erythrocyte sample adding area and a sample adding area from the upstream side to the downstream side; the reactionpart is provided with at least one detection point and a contrast point, wherein at least one detection point is coated and cured with an anti-human IgG antibody, and the contrast point is coated andcured with an anti-RBC antibody. When the kit is used, only one-step sample adding, red blood cell adding and flushing fluid adding are needed, and a result can be obtained after 3-5 minutes.
Owner:INTEC PROD INC
Crossmatching blood samples
ActiveUS10161942B2Reduce and preventMinimise any false positiveBiological material analysisBiological testingCrossmatching bloodPre transfusion
Owner:QBD QS IP
Novel immune medicine for treating solid tumors
ActiveCN111840210APoor treatment effectShrink tumorPharmaceutical delivery mechanismVertebrate antigen ingredientsTumor reductionAntiendomysial antibodies
The invention provides a novel immune medicine for treating solid tumors, the immune medicine comprises a virus expression vector for simultaneously expressing a Fut1 gene and an ABO blood group gene,and the ABO blood group gene comprises an N-acetylgalactosamine transferase gene and / or a galactosyl transferase gene. According to the immune drug, a human ABO blood group gene is cloned to a medical drug-grade lentiviral vector; co-expression with a Fut1 gene is carried out; the prepared medical drug-grade lentiviral drug is injected into a tumor part through a solid tumor local injection method; according to the present invention, the target gene sequence is permanently translated in tumor cells, such that a large amount of the blood group antigen is expressed on the surface of the tumor cell membrane, and the blood group antigen can be recognized by the corresponding blood group antibody existing in serum so as to activate the complement so as to kill the tumor cells and achieve the tumor reduction purpose;
Owner:王磊 +1
Microtube for blood type testing, integrated abo/rhd blood type testing card and its preparation
ActiveCN105223366BGuaranteed SensitivityGuaranteed FeaturesBiological testingSerum igeRed blood cell
Owner:SHENZHEN DAKEWE BIOENG
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