The invention provides a multi-rotor hybrid power plant protection unmanned aerial vehicle, which comprises a gasoline engine rotor, an engine, a battery, aircraft frames, a foot support frame, a pesticide box, a spray rod, a spray head and a remote controller, wherein the gasoline engine rotor is a single wing; the number of the aircraft frames is an even number, and the aircraft frames are uniformly and horizontally arranged on the periphery of a fixing plate arranged in the middle of the aircraft frames; the end part of each aircraft frame is provided with a small rotor, and each small rotor is driven by a small motor; two spoilers are arranged on the aircraft frame arranged under the single gasoline engine rotor. The multi-rotor hybrid power plant protection unmanned aerial vehicle has the advantages that the structure is simple, the self weight is light, the manufacturing cost is low, the load capacity is great, the duration time is long, the flight is stable, no pollution is caused, the repair is simple, and the like. The repair and the flight training are very simple, the long-time maintenance-free effect can be realized, and the after-sales service intensity is greatly reduced; the operation and control simplicity and stability of the unmanned aerial vehicle are greatly improved; the maintenance simplicity is realized; the time cost is reduced; the use efficiency of a battery is greatly improved.