The application discloses an anti-
red blood cell membrane
antibody and application thereof, and relates to a
heavy chain and a light chain, wherein the
amino acid sequence of the variable region of the
heavy chain is shown as SEQ ID NO:1, or is a conservative
mutant obtained by adding, deleting, replacing or modifying one or more amino acids of the sequence; the
amino acid sequence of the variable region of the light chain is shown as SEQ ID NO:2, or is a conservative
mutant obtained by adding, deleting, replacing or modifying one or more amino acids of the sequence; the sequences of CDR1, CDR2 and CDR3 of the variable region of the
heavy chain are shown as SEQ ID NO:3, SEQ ID NO:4 and SEQ ID NO:5; the sequences of CDR1, CDR2 and CDR3 of the variable region of the light chain are shown as SEQ ID NO:6, SEQ ID NO:7 and SEQ ID NO:8; and the anti-
red blood cell membrane
antibody is used in the construction of a
bifunctional antibody reagent. The anti-
red blood cell membrane antibody is used in
chromatography detection, and rbc can be intercepted on a sample pad by
processing on the sample pad, so that
whole blood can be detected.