21 results about "Functional medicine" patented technology

The invention discloses lotus leaf homogeneous polysaccharide LLP3-1 as well as a separation and purification method and application thereof, and belongs to the technical field of plant polysaccharide. The lotus leaf homogeneous polysaccharide LLP3-1 is composed of rhamnose, arabinose, galactose and galacturonic acid, the molar percentage of monosaccharide is 21.95: 25.33: 21.10: 31.62, the lotus leaf homogeneous polysaccharide LLP3-1 is acidic pectin polysaccharide with RG-I as a main structural domain and with part of side chains, the main chain is mainly composed of galacturonic acid and rhamnose, and the side chains are mainly composed of arabinose and galactose. The lotus leaf homogeneous polysaccharide LLP3-1 has the beneficial effects that the lotus leaf homogeneous polysaccharide LLP3-1 can obviously improve the symptoms of ulcerative colitis; the compound can be widely applied to preparation of medicines for treating ulcerative colitis, medicines for inhibiting proinflammatory factor secretion, antioxidation medicines, medicines for improving intestinal barrier integrity and functions, medicines for promoting short-chain fatty acid generation and medicines for improving intestinal flora disorder of ulcerative colitis.

The invention discloses a lactobacillus delbrueckii subsp. Bulgaricus CCFM1520 for transforming curcumin to produce tetrahydrocurcumin to relieve nervous anxiety, and belongs to the technical field of microorganisms. The lactobacillus delbrueckii subsp. Bulgaricus CCFM1520 screened by the invention has the capability of converting curcumin, and can utilize curcumin and generate tetrahydrocurcumin. The invention further provides a synbiotic preparation prepared from the lactobacillus gasseri CCFM1481 and curcumin, the synbiotic preparation can be used as an anti-fatigue functional medicine, the individual behavioral memory level can be improved, the imbalance of body neurotransmitters (DA, 5-HT and NE) can be slowed down, the expression of body neuroprotection related genes (BDNF, TrkB, DRD1 and TH) can be improved, and the synbiotic preparation has a huge application prospect.

The invention belongs to the field of biological medicine, and particularly relates to a dendritic multi-targeting antibody coupling carrier, an antibody coupling medicine as well as a preparation method and application of the dendritic multi-targeting antibody coupling carrier and the antibody coupling medicine. The dendritic multi-targeting antibody coupling carrier is composed of a targeting module and a drug coupling module, wherein the targeting module has multispecificity and a multivalent binding receptor function; the drug coupling module can realize fixed-point coupling and high drug loading capacity of drugs. The fusion proteins of the two modules can be specifically bound by a spy reaction through spontaneously formed covalent bonds. According to the present invention, the dendritic multi-targeting antibody coupling carrier is further utilized to construct the antibody coupling drug, such that the targeting property of the drug is improved, the relative drug loading capacity of the drug is improved, and the tumor treatment effect of the antibody coupling drug is finally improved.

The invention discloses lactobacillus gasseri CCFM1481 for converting curcumin to produce tetrahydrocurcumin and enhance an anti-fatigue effect, and belongs to the technical field of microorganisms. The lactobacillus gasseri CCFM1481 obtained through screening has the capacity of converting curcumin, curcumin can be utilized, tetrahydrocurcumin can be generated, and the conversion rate is 89.83%. The invention further provides a synbiotic preparation prepared from the lactobacillus gasseri CCFM1481 and curcumin, and the synbiotic preparation can be used as an anti-fatigue functional medicine and has a good application prospect and an industrialization foundation.

The utility model belongs to the technical field of medical auxiliary instrument, concretely relates to a percutaneous electric medicine synergic treatment device, including host computer and with the electric medicine treatment unit of host computer electric connection, the electric medicine treatment unit includes annular adhesive member, ring electrode, drug loading disc and medicine gel piece, annular adhesive member, ring electrode and drug loading disc coaxial arrangement, ring electrode is fixed between drug loading disc side surface and annular adhesive member inboard, the thickness of drug loading disc is less than the thickness of ring electrode, and the inboard of ring electrode and the surface of drug loading disc form the recessed cavity for accommodating medicine gel piece, and when medicine gel piece sets up in recessed cavity, medicine gel piece side surface and ring electrode inboard are pasted. The utility model can improve medicine transdermal absorption rate on the basis of guaranteeing electric stimulation itself effect, thereby more effectively realizes electric stimulation and medicine synergic effect, to improve synergic curative effect, realizes the flexible replacement use of different function medicine gel piece, satisfies the individualized treatment demand.

This utility model relates to the field of medical packaging technology and provides a multifunctional drug container interface, including a capsule and a sealing plug. One end of the capsule has an integrally formed base post, and the base post has wings on two opposite sides for welding to an infusion bag or for holding. The capsule has an interior cavity for storing drugs, with open ends. One open end has a sealing diaphragm that can be ruptured by squeezing the capsule. The sealing plug is located at the other open end. When oral or intravenous administration is required, a steel or plastic needle can be inserted into the cavity through the sealing plug. The interface provided by this utility model can be used for welding to infusion bags as an infusion accessory, and also as a container for oral medications, making the interface versatile and reducing packaging material waste.

The utility model discloses a pharmacy multifunctional medicine shelf partition relates to pharmacy equipment field, including fixed axle, soft partition and accomodation axle, and fixed axle fixed connection is in soft partition one side, and the other side fixed connection of soft partition is in accomodation axle inside, and soft partition is magnetic material, and whole can be bent, and fixed axle includes axle body main part, first sucking disc, second sucking disc and third sucking disc, and first sucking disc and second sucking disc fixed connection are in axle body main part outside, and third sucking disc fixed connection is in axle body main part bottom end, the utility model provides a pharmacy multifunctional medicine shelf partition, and the soft partition of the device is the writing board with magnetism, can be convenient for pharmacist to write medicine expiration date and other related information on it, and is designed as erasable, and the fixed axle and accomodation axle of the device can utilize built -in sucking disc structure and be adsorbed and fixed in the arbitrary place of medicine shelf, and can be moved at will according to demand simultaneously, and can accomodate and save space at any time when not using.

1. Name of the product in this design: Medicine Box. 2. Purpose of this design: For use in a multi-functional medicine box. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention provides the application of *Pleurotus oosporum* polysaccharide in the preparation of drugs and health foods that regulate intestinal barrier function or protect against intestinal damage-related diseases. Its protective effect against a mouse model of intestinal damage induced by sodium dextran sulfate was investigated. Results showed that *Pleurotus oosporum* polysaccharide significantly improved symptoms such as weight loss, loose stools, and colonic atrophy caused by intestinal damage in mice, reduced the disease activity index, inhibited colonic epithelial destruction, inflammatory cell infiltration, and goblet cell necrosis, and enhanced intestinal mucosal barrier function. As a fungus, *Pleurotus oosporum* has high safety and is a potential source of active ingredients against intestinal damage, showing promising development prospects in intestinal barrier protection.

1. The name of the design product: multi-functional medicine storage box. 2. The use of the design product: medicine storage box. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best shows the design points: perspective view 1.

This invention provides a functional medicine proactive health management method and system for large-scale model fine-tuning engineering. The method includes the following steps: S101, pre-training a general large-scale model using functional medicine literature and clinical guidelines; S102, fine-tuning the general large-scale model using medical tasks to form a medical-specific large-scale model; S103, integrating LSTM and Transformer temporal algorithms, and introducing autoencoder model reconstruction error as an anomaly scoring indicator; S104, integrating reinforcement learning and generative adversarial networks to output personalized health intervention suggestions based on user health risks; S105, collecting user health behavior data in real time through IoT wearable devices and portable detection instruments, preprocessing the health behavior data to generate a structured health dataset, and inputting it into the medical-specific large-scale model for user health assessment and management. This invention achieves a closed-loop process from data collection, accurate assessment, dynamic early warning to personalized intervention, meeting the needs of functional medicine proactive health management.

The invention provides an application of fructus psoraleae polysaccharide in preparation of a medicine or health food for regulating an intestinal barrier function. Specifically, the fructus psoraleae polysaccharide acts on an intestinal tract. In the intestinal tract action process, the fructus psoraleae polysaccharide effectively improves damaged intestinal tract barrier repair; the number of CD4 + and CD8 + T cells in intestinal tracts is increased, and the immune barrier of the intestinal tracts is improved; according to the present invention, the expression of tight junction proteins Claudin-1, Occludin and ZO-1 can be promoted, the intestinal mechanical barrier can be repaired and enhanced, and the polypeptide can be used for preventing, relieving or treating intestinal barrier damage, has excellent performance in the regulation of the intestinal barrier function, and has good application prospects.

1. The name of the design product: multi-functional medicine transport case. 2. The use of the design product: for medicine transport. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view. 5. The right view is the same as the left view, and the right view is omitted.

The invention discloses a green tea extract, hydrolyzed keratin and vitamin C composition for delaying senescence of cats and dogs, and belongs to the technical field of pet anti-aging food preparation. The composition of the three components can promote the proliferation of cat mammary gland cells and dog mammary gland cells, and obviously improve the cell proliferation capacity decline caused by actinomycin D; meanwhile, the expression level of senescence-related proteins (such as p16, p21, p53 and the like) can be down-regulated, and the up-regulation trend of the senescence-related proteins in a senescence-induced state can be reversed. In addition, the composition has a remarkable protection effect on oxidative damage of cat mammary gland cells and dog mammary gland cells, and is regulated and controlled by a Hippo signal channel. Animal experiment results show that the composition can improve the athletic ability and oxidative stress level of aged mice and delay the aging process of the aged mice. The technical scheme provided by the invention is high in safety and remarkable in biological activity, and has a wide application prospect in the fields of pet anti-aging nutrition intervention and functional medicine development.

The utility model relates to the technical field of medical tools, in particular to a multifunctional medicine box which comprises a box body, a cover plate, a storage box, a plurality of partition plates, a plurality of turning covers, a plurality of ultraviolet lamps, a circuit board, a storage battery, a help seeking assembly and a positioning assembly. The box body is provided with a plurality of grooves, the ultraviolet lamps are arranged in the corresponding grooves respectively, the box body is provided with a cavity, the circuit board is arranged in the cavity, the storage battery is electrically connected with the circuit board, the positioning assembly is arranged in the cavity, and the cover plates are attached to the cavity. By means of the arrangement, the medicine box has the functional effect and the sterilization function, and medicine is prevented from being polluted.

The application relates to the field of biological medicine, and discloses application of a treatment target in preparation of a drug for treating heart function after myocardial infarction, and the treatment target is NR1D1. The application discloses that NR1D1 is a key target for treating heart dysfunction after myocardial infarction, and it is proved that by exciting NR1D1, the heart function can be significantly improved, the myocardial injury can be reduced, the fibrosis and cell apoptosis can be inhibited, NR1D1 plays a protection role by directly activating RABGAP1L, a "HIF-PHIs-NR1D1-RABGAP1L" signal shaft is formed, a new target and mechanism are provided for the treatment of myocardial infarction, an experimental basis is provided for a new use of Roxadustat in the protection of heart function after myocardial infarction, and the application has a good clinical application prospect.

The utility model relates to the technical field of medicine bags, and provides a multifunctional medicine bag which comprises a box body and a box cover rotatably arranged on the box body, the box body and the box cover are connected through a zipper, at least two medicine bottle grooves are formed in the box body, one side of each medicine bottle groove is provided with a threaded hole, the threaded hole is in threaded connection with a threaded rod, and the threaded rod is connected with the box cover through a zipper. One end of the screw rod is rotationally connected with a fixing plate, at least two medicine box grooves are formed in the box body, at least one sliding groove is formed in the side wall of each medicine box groove, a sliding strip is arranged in each sliding groove in a sliding mode, a bearing plate is arranged at the bottom of each sliding strip, medicine boxes are placed on the bearing plates, and the medicine boxes can be lifted by pulling the sliding strips. The medicine bag is suitable for stably clamping medicine bottles with different sizes, the medicine box on the bearing plate is lifted through the sliding strip, the needed medicine box is very easy to take out, and the technical problems that an existing medicine bag is poor in fixing effect, and medicine is inconvenient to take out rapidly are solved.

The utility model discloses a multi -functional medicine -dispensing trolley belongs to medicine -dispensing trolley technical field, this medicine -dispensing trolley includes the cabinet body, the cabinet body bottom four corners are installed with universal wheel, the cabinet body one side is installed with a plurality of front drawers, the both sides of cabinet body are installed with domestic garbage can, medical waste can, storage box and storage basket, the cabinet body one side top is installed with handle, the both sides rotation of handle install horizontal board, the horizontal board one end is provided with the sliding slot, the both sides of cabinet body are provided with the annular groove of matching with the horizontal board, the sliding slot inner wall fixed mounting baffle, the baffle one side rotation installs screw rod, the both sides of cabinet body are provided with the screw groove of matching with screw rod, the both sides of handle pass through gear set with screw rod transmission connection, this medicine -dispensing trolley can classify and store medicine, mark information, and it is convenient for garbage disposal and article storage, handle adjustable, still increased the space of placing.

The invention belongs to the field of medical materials, and particularly relates to a time-space matched patterned hydrogel dressing and a preparation method thereof. The preparation method comprises the following steps: preparing a hydrophilic-hydrophobic interval pattern dressing, preparing drug-loaded hydrogel, and preparing the hydrophilic-hydrophobic interval dot matrix gel dressing by a rolling water method. Space confinement distribution of drugs is achieved through the hydrophilic-hydrophobic patterned substrate, drugs with different functions are accurately delivered to specific areas of a wound, and the limitation of traditional homogenization design is broken through; based on the slow release characteristic of the double-gel system, the dynamic controlled release of the medicine in different healing stages is realized, and the dynamic requirement of the whole wound healing period is met; the antibacterial adhesion characteristic of the super-hydrophobic coating and the antibacterial / anti-fibrosis function of the drug-loaded hydrogel are combined, the anti-infection capacity is improved through the synergistic effect, the wound surface microenvironment is optimized, and the contradiction between safety and functionality of a traditional antibacterial dressing is solved.

1. The name of the design product: multi-functional medicine cutter for cutting (QY009). 2. The use of the design product: for cutting, grinding and storing of medicine tablets. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.

According to the spreading mechanism assembling device, an umbrella head pipe and a functional medicine pipe are fed to the feeding mechanism, the assembling mechanism assembles the umbrella head pipe and the functional medicine pipe, the conveying mechanism conveys the umbrella head pipe and the functional medicine pipe which are assembled on the feeding mechanism to the machining and positioning mechanism, the machining and positioning mechanism conducts gluing on the functional medicine pipe, and then the umbrella head pipe and the functional medicine pipe are assembled. The umbrella head pipe and the functional medicine pipe are connected in a buckled mode, then drilling, dispensing and rivet punching are conducted on the connecting position of the umbrella head pipe and the functional medicine pipe, so that connection between the umbrella head pipe and the functional medicine pipe is stable, and the machined umbrella head pipe and the machined functional medicine pipe are placed on the discharging frame through the conveying mechanism. Therefore, the umbrella head pipes and the functional medicine pipes in the spreading mechanisms are automatically assembled, and the consistency in the spreading mechanisms is guaranteed through gluing, drilling and riveting treatment on the spreading mechanisms.