Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

31 results about "Perfluorohexane" patented technology

Perfluorohexane (C₆F₁₄), or tetradecafluorohexane, is a fluorocarbon. It is a derivative of hexane in which all of the hydrogen atoms are replaced by fluorine atoms. It is used in one formulation of the electronic cooling liquid/insulator Fluorinert for low-temperature applications due to its low boiling point of 56 °C and freezing point of −90 °C. It is odorless and colorless. Unlike typical hydrocarbons, the structure features a helical carbon backbone.

Preparation method of alpha, omega-diiodo perfluoroalkane

The invention provides a preparation method of alpha, omega-diiodo perfluoroalkane, and belongs to the technical field of iodo perfluoroalkane synthesis. The preparation method disclosed by the invention comprises the following steps: under a protective atmosphere, enabling a nano flower type magnesium fluoride catalyst, 1, 2-diiodo tetrafluoroethane and tetrafluoroethylene to react, so as to obtain 1, 4-diiodo perfluorobutane and 1, 6-diiodo perfluorohexane. The nano flower type magnesium fluoride catalyst has high specific surface area and abundant coordination unsaturated sites, can effectively activate reactant molecule bonding sites, and avoids the problems of side reaction and catalyst deactivation caused by free radical paths; by optimizing the pore structure and reaction conditions of the catalyst, efficient synergistic conversion of IPF-2 and TFE can be realized, and the selectivity and yield of IPF-4 and IPF-6 are remarkably improved. The method provided by the invention has the advantages of mild conditions, safe operation, adjustable product distribution and the like, and meets the requirements of industrial production on high-selectivity fluorine-containing bifunctional compounds.
Owner:ZHEJIANG NORMAL UNIV +1

Flame-retardant electrolyte, preparation method and application thereof

This invention belongs to the field of lithium-ion battery flame retardant technology, specifically relating to a flame-retardant electrolyte, its preparation method, and its application. The electrolyte comprises: lithium salt, carbonate organic solvent, co-solvent, and flame-retardant additive; the concentration of lithium salt in the electrolyte composed of lithium salt and carbonate organic solvent is 0.5–5 mol / L; the volume ratio of carbonate electrolyte to flame-retardant additive is 100:(1–30); the volume ratio of co-solvent to flame-retardant additive is (4–120):(1–5); the co-solvent is a solvent capable of dissolving the flame-retardant additive, and the flame-retardant additive is a perfluorohexane derivative. This invention proposes introducing a co-solvent that does not interact with lithium ions into the electrolyte. Through the bridging effect of the co-solvent, the insoluble flame retardant is introduced into the conventional electrolyte. The flame-retardant electrolyte prepared by this method does not deteriorate its electrochemical performance due to the addition of the flame retardant, thus solving the problem of incompatibility between the flame-retardant performance and electrochemical performance of lithium-ion battery electrolytes.
Owner:HUAZHONG UNIV OF SCI & TECH +1

A method for preparing a high carbon number diiodoperfluoroalkane

ActiveCN117843440BAlkaneCarbon number
The application relates to the technical field of fluorine-containing iodoalkane preparation, in particular to a preparation method of high-carbon-number diiodoperfluoroalkane, which comprises the following steps: reacting tetrafluoroethylene and elemental iodine to generate diiodotetrafluoroethane; and under the action of a catalyst, the diiodotetrafluoroethane is subjected to telomerization reaction with tetrafluoroethylene to generate high-carbon-number diiodoperfluorobutane and diiodoperfluorohexane; and the catalyst is a metal nickel catalyst supported on silicon dioxide. The metal nickel catalyst supported on silicon dioxide is used to make the diiodotetrafluoroethane and the tetrafluoroethylene subjected to telomerization reaction to obtain diiodoperfluoroalkane with higher carbon number. The application has the advantages of simple process, low reaction temperature and the like, and can significantly improve the yield of diiodoperfluorobutane and diiodoperfluorohexane.
Owner:ZHONGHAO CHENGUANG RES INST OF CHEMICALINDUSTRY CO LTD

Composite particles

To provide composite particles that can efficiently generate ammonia. [Solution] The present invention provides composite particles in which an ammonia-generating compound is supported on a carrier, wherein the carrier is at least one selected from the group consisting of silicon carbide, alumina, titania, silica, zirconia, ceria, silica-alumina, calcia, magnesia, and carbon black, and the ammonia-generating compound is a compound that generates ammonia upon heating, is insoluble in perfluorohexane, and has a specific gravity lower than that of perfluorohexane at 20°C.
Owner:NISSHIN ENG +1

Cleanness detection device for perfluoropolyether lubricating oil

The invention discloses a cleanliness detection device for perfluoropolyether lubricating oil, and relates to the technical field of lubricating oil cleanliness detection, the cleanliness detection device comprises a body, and a light resistance detection assembly for detecting the cleanliness of an oil sample is installed in the body. According to the invention, the micro vacuum pump and the compressed gas cylinder are cooperatively linked, and pertinent medium selection of a fluorocarbon solvent (such as perfluorohexane) and high-purity nitrogen is matched, so that the detection pipe is firstly efficiently cleaned, and then residual cleaning liquid in the pipeline is thoroughly removed through backflushing and blow-drying, so that the detection deviation caused by oil sample dilution and micro-particle adsorption is fundamentally avoided, and the detection accuracy is improved. The accuracy and authenticity of the cleanliness detection result are greatly improved, the high-precision quality control requirement in the high-end field is met, through the linkage design of the telescopic valve plate, the opening and closing valve plate and other structures, automatic and orderly switching of cleaning, blow-drying, oil sample extraction and detection procedures is achieved, manual intervention of the pretreatment process is not needed, the operation process is simplified, the detection efficiency is improved, and the detection cost is reduced. And the labor cost is reduced.
Owner:DONGGUAN HONGWEI LUBRICATING OIL CO LTD

Directional synthesis process of electronic-grade hexafluoroethane based on composite catalyst

The invention relates to the technical field of electronic-grade fluorine-containing special gas synthesis, in particular to an electronic-grade hexafluoroethane directional synthesis process based on a composite catalyst, which comprises the following steps: S1, carrying out reflux treatment on activated carbon by hydrofluoric acid-nitric acid mixed liquor, sequentially loading aluminum trichloride, cesium fluoride, lanthanum oxide and graphene quantum dots, and roasting in a nitrogen atmosphere to prepare the composite catalyst; s2, mixing tetrafluoroethylene and hydrogen fluoride in proportion, dehydrating through a molecular sieve, and removing impurities through a nano-zinc oxide coating purification tower; s3, introducing the raw materials into a fixed bed with a guide plate, and carrying out segmented temperature control reaction under the adjustment of a composite catalyst and perfluorohexane; and S4, condensing, alkali-washing and drying the reaction product, and rectifying in a rectifying tower to obtain the electronic-grade hexafluoroethane. And S5, adsorbing the rectification tail gas by a composite adsorbent, and resolving and recycling the raw materials for pretreatment. The process improves the selectivity and purity of hexafluoroethane, prolongs the service life of the catalyst, is good in regeneration effect, reduces energy consumption and raw material loss, reduces wastewater discharge, and meets the requirements of the semiconductor industry.
Owner:HEFEI JINSHI CHEMICAL CO LTD

Multi-temperature-range ice slurry cold storage system for liquefied natural gas cold energy cascade recovery

The invention relates to the technical field of energy recycling, in particular to a multi-temperature-range ice slurry cold storage system for liquefied natural gas cold energy gradient recycling. Comprising a deep cooling stage unit, an intermediate cooling stage unit and a shallow cooling stage unit which are sequentially connected in series in the flowing direction of liquefied natural gas, and each stage unit integrates the functions of ice slurry preparation, slurry separation, dynamic storage and cooling capacity output and is provided with a monitoring regulation and control assembly; the refrigerant circulating mechanism is connected with each stage of unit to form a closed cycle, light liquid toluene is used as a refrigerant to transfer cooling capacity, and a light refrigerant layer, an ice slurry generation base liquid layer and a heavy liquid perfluorohexane isolation liquid layer are arranged in each stage of ice slurry making tank from top to bottom. According to the system and the method, LNG full-temperature-range cold energy release from-162 DEG C to 0 DEG C is adapted through a multi-stage unit, precise energy and mass matching is realized by utilizing freezing point differences of base liquids with different concentrations, ice blockage is avoided by virtue of an immiscible isolation liquid layer, and the energy utilization rate and the operation stability are improved in combination with refrigerant recovery and a real-time monitoring mechanism.
Owner:DALIAN UNIV OF TECH

Method of forming a living coating on the surface of a degradable occlusion device and degradable occlusion device

The embodiment of the application relates to the technical field of medical coating materials, and particularly relates to a method for forming an active coating on the surface of a degradable occlusion device and the degradable occlusion device, the method comprising the following steps: preparing perfluorohexane liposomes loaded with stromal cell-derived factor-1 alpha (SDF-1 alpha); preparing polylactic acid-glycolic acid copolymer@rapamycin@nitric oxide donor nanoparticles; preparing a methacrylated gelatin-tannic acid hydrogel carrier; mixing the liposomes and the nanoparticles into the hydrogel carrier; soaking the degradable occlusion device in the mixture obtained in the previous step, and performing light crosslinking treatment on the mixture, so that an active coating is formed on the surface of the degradable occlusion device. Therefore, comprehensive consideration of "endothelialization repair in the early implantation period - myocardial tissue remodeling after implantation" is realized, controllable time-sequencing repair of the degradable occlusion device on the heart defect site is ensured, and the endogenous functional repair effect of the heart of a patient is improved.
Owner:FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE

Compositions and molded articles containing fluorine-containing polymers

PendingJP2026061973ACarbide siliconPolymer science
To provide a composition that allows for the crosslinking of fluorine-containing polymers in a short time, and that yields molded articles with low compression set. [Solution] A composition containing a fluorine-containing polymer and composite particles, wherein the composite particles are composite particles on which an ammonia-generating compound is supported, the support is at least one selected from the group consisting of silicon carbide, alumina, titania, silica, zirconia, ceria, silica-alumina, calcia, magnesia, and carbon black, and the ammonia-generating compound is a compound that generates ammonia upon heating, is insoluble in perfluorohexane, and has a specific gravity less than that of perfluorohexane at 20°C.
Owner:DAIKIN INDUSTRIES LTD

A nano-lipid preparation for encapsulating perfluorohexane and antioxidant, its preparation method and application for preparing a medicine for treating myocardial infarction

The application belongs to the field of biological medicine, and discloses a nano-lipid preparation for loading perfluorohexane and an antioxidant, wherein the nano-lipid preparation is a core-shell structure, the core-shell structure takes a phospholipid liposome membrane layer as an outer shell, and perfluorohexane and the antioxidant loaded in the outer shell serve as an inner core; the phospholipid liposome membrane layer is made of hydrogenated lecithin, distearoyl phosphatidyl ethanolamine-polyethylene glycol 2000 and cholesterol; and the application discloses an application of the nano-lipid preparation for loading perfluorohexane and the antioxidant in preparation of a medicine for treating myocardial infarction. The nano-lipid preparation has a suitable particle size, can be passively targeted and enriched to a myocardial infarction site, is stable, has a high encapsulation efficiency, and has a simple administration mode; after the lipid preparation is taken by myocardial cells, oxygen and the antioxidant are released, the oxygen can relieve an anoxic condition of a myocardial ischemia site, and the antioxidant can reduce ROS damage, both of which play a synergistic role, improve the survival rate of ischemic myocardial cells, and improve heart function.
Owner:CHINA PHARM UNIV

Method for forming active coating on surface of degradable plugging device and degradable plugging device

The embodiment of the invention relates to the technical field of medical coating materials, in particular to a method for forming an active coating on the surface of a degradable plugging device and the degradable plugging device, and the method comprises the following steps: preparing a perfluorohexane liposome loaded with stromal cell-derived factor-1 alpha (SDF-1 alpha); preparing nano particles of the polylactic acid-glycolic acid copolymer, the rapamycin and the nitric oxide donor; preparing a methacryloyl gelatin-tannic acid hydrogel carrier; mixing the liposome and the nanoparticles into the hydrogel carrier; and soaking the degradable plugging device in the mixture obtained in the previous step, and carrying out photo-crosslinking treatment on the mixture, so that an active coating is formed on the surface of the degradable plugging device. Therefore, comprehensive consideration of'implantation early endothelial repair-implantation later cardiac muscle tissue remodeling 'is realized, controllable sequential repair of the degradable plugging device on the heart defect part is ensured, and the endogenous function repair effect of the heart of a patient is improved.
Owner:FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE

Phase change explosion suppression device for solid hydrogen storage device

The utility model discloses a phase change explosion suppression device for a solid hydrogen storage device, and belongs to the technical field of safety devices or accessories of hydrogen storage devices. The device comprises a liquid storage tank, a liquid inlet pipe, a liquid inlet electric valve, a multi-nozzle liquid spraying pipe, a porous nozzle, a temperature sensor and a stainless steel solid hydrogen tank. The multi-nozzle liquid spraying pipe is inserted into the stainless steel solid hydrogen tank and connected with the liquid inlet pipe through the liquid inlet electric valve, and the rear end of the multi-nozzle liquid spraying pipe is connected with the liquid storage tank. When the temperature sensor detects that the temperature reaches a threshold value, the liquid inlet electric valve is opened, perfluorohexane flows through the liquid inlet pipe from the liquid storage tank and then can flow into the multi-nozzle liquid spraying pipe, high-pressure fine liquid mist is generated through the multi-hole nozzles, and heat can be rapidly absorbed for cooling. According to the utility model, the explosion in a solid hydrogen storage place can be quickly inhibited, the use is more convenient and faster, the safety is improved, and the utilization rate and the safety can be improved as perfluorohexane does not react with hydride.
Owner:DALIAN UNIV OF TECH

Composition containing fluorine-containing polymer, and molded article

PCT designated stageWO2026071239A1Carbide siliconFluoropolymer
Provided is a composition containing a fluorine-containing polymer and composite particles, wherein: the composite particles are composite particles in which an ammonia-generating compound is supported on a carrier; the carrier comprises at least one selected from the group consisting of silicon carbide, alumina, titania, silica, zirconia, ceria, silica alumina, calcia, magnesia, and carbon black; and the ammonia-generating compound is a compound that generates ammonia when heated, is insoluble in perfluorohexane, and has a specific gravity smaller than the specific gravity of perfluorohexane at 20°C.
Owner:DAIKIN INDUSTRIES LTD

Method for producing fluororesin

The present invention pertains to: a fluororesin that includes a residue unit represented by formula (1), and a terminal group represented by formula (2); and a fluororesin that includes a residue unit represented by formula (1) and has a transmittance of 50% or more measured at an optical path length of 10 mm and a wavelength of 275 nm when dissolved in perfluorohexane to produce a 10 wt % perfluorohexane solution.In formula (1): Rf1, Rf2, Rf3, and Rf4 each independently represent one selected from the group consisting of fluorine atoms, C1-7 linear perfluoroalkyl groups, C3-7 branched perfluoroalkyl groups, or C3-7 cyclic perfluoroalkyl groups; the perfluoroalkyl groups may have an etheric oxygen atom; Rf1, Rf2, Rf3, and Rf4 may bond to each other to form a ring having 4 to 8 carbon atoms; and the ring may include an etheric oxygen atom.In formula (2), i is an integer of 3-20. The present invention provides: a fluororesin that includes an oxolane ring, has suppressed yellowing after heating and melting, and especially has reduced discoloration, even in molding of thick products; and a method for producing said fluororesin.
Owner:TOSOH CORP

A time-sharing sampling system for sampling uranium hexafluoride mixed gas

The application relates to the technical field of sampling, in particular to a time-sharing sampling uranium hexafluoride mixed gas sampling system. The system comprises a first sampling device, a second sampling device and a third sampling device which are connected with a sampling pipeline through electromagnetic valves respectively, the sampling outlet of the first sampling device is connected with a first vacuum tank, the first vacuum tank is connected with a vacuum pump, a solid particle sampling membrane is arranged between the sampling inlet and the sampling outlet, the sampling outlet of the second sampling device is connected with a second vacuum tank, the second vacuum tank is connected with a vacuum pump, perfluorohexane solution is arranged between the sampling inlet and the sampling outlet, the sampling outlet of the third sampling device is connected with a third vacuum tank, the third vacuum tank is connected with a vacuum pump, hydrogen fluoride sampling powder is arranged between the sampling inlet and the sampling outlet, and a control unit is used for controlling the electromagnetic valves and the vacuum pumps in the sampling process. The uranium hexafluoride mixed gas sampling system can sample different substances in the uranium hexafluoride mixed gas in a time-sharing and fixed-point mode.
Owner:CHINA INST FOR RADIATION PROTECTION

A filtration membrane and a method for producing the same

PendingCN122321652AFiltration membraneMeth-
This invention provides a filter membrane and its preparation method. The preparation method includes the following steps: placing a porous filter membrane substrate in an environment containing plasma and a precursor, and performing plasma treatment to obtain the filter membrane; wherein the precursor includes at least one selected from hexamethyldisiloxane, perfluorooctyltriethoxysilane, pentane, ethylene, toluene, perfluorohexane, styrene, divinylbenzene, hexamethyldisiloxane, tetramethylsilane, tetraethoxysilane, tetrafluoroethylene, and hexafluoropropylene. The filter membrane obtained by this preparation method can significantly reduce the swelling rate and simultaneously increase the permeation flux in organic solvents, achieving precise molecular weight cutoff.
Owner:CHINA UNIV OF PETROLEUM (BEIJING) +1

Ultrasonic responsive apoptosis bionic targeting nano-carrier delivery material and preparation method thereof

The invention belongs to the technical field of nano-drugs, and particularly relates to an ultrasonic responsive apoptosis bionic targeting nano-carrier delivery material and a preparation method thereof. According to the invention, a beta-cyclodextrin polymer (PCD) is used as a core skeleton, and phosphorylserine (PS) is modified through a phosphate bond so as to enhance the targeting ability; pFH (perfluorohexane) is entrapped as an ultrasonic response core under a low-temperature condition by utilizing interaction of a subject and an object; liposome (soya bean lecithin and cholesterol) is used for outer layer coating, so that the in-vivo stability and the circulation half-life period of the system are remarkably improved, and the breakthrough of the PCD-PS system from local administration to systemic administration is realized for the first time; the system has excellent ultrasonic responsiveness, and can be accurately triggered at a targeted part and release contents; meanwhile, the apoptotic cell imitating design endows the system with active targeting property, and the dual-coating structure ensures the stability of in-vivo circulation, so that the synergistic interaction of stable circulation, active targeting and ultrasonic triggering is realized.
Owner:JINAN UNIVERSITY

Radiation resistant sealing material for photolithography processes and method for producing same

The application discloses a kind of radiation-resistant sealing materials for photoetching process and preparation method thereof, belong to high molecular sealing material technical field.The material is made of fluorine rubber raw rubber, 1-iodine perfluorohexane or 1-iodine perfluorooctane, reinforcing filler, bisphenol AF vulcanizing agent and benzyl triphenyl phosphonium chloride accelerator, etc.According to specific weight part, it is made by batch dropwise mixing and gradual temperature two-step vulcanization.The application utilizes perfluoroalkyl iodide under plasma C-I bond preferentially homolysis generates I·, terminates fluorine rubber free radical chain degradation;And through theoretical calculation and ion chromatography verification, ensure that processing process does not decompose, no corrosive iodine ion release in service.The application breaks the application technology prejudice of halogen, solves the defect that conventional fluorine rubber particle releases high, plasma life is short, avoids the problem that perfluoroether rubber is high in cost and difficult to process, the obtained material is low in particle release amount, long in radiation life, small in compression permanent deformation, adapts to 7nm and below node semiconductor equipment sealing demand, easy to scale up.
Owner:ANHUI DUOKEN INNOVATION TECHNOLOGY CO LTD

A method and apparatus for preparing perfluorohexane

This application relates to a process for preparing fluorinated liquids, specifically a method and apparatus for preparing perfluorohexane. The method involves first reacting hexafluoropropylene with a fluorine-containing gas to obtain crude perfluorohexane; then subjecting the crude perfluorohexane to primary and secondary alkaline washing, followed by water removal; and finally, primary and secondary condensation. The primary condensation yields the product perfluorohexane, while the secondary condensation recovers hexafluoropropylene for recycling. The apparatus comprises a reaction tower, a buffer tank, a primary alkaline washing tower, a secondary alkaline washing tower, a drying tower, a first cold trap, and a second cold trap, connected in sequence. This application features a simple production process, high hexafluoropropylene conversion rate, high product purity, and low overall cost, demonstrating good economic benefits and application prospects.
Owner:PERIC SPECIAL GASES CO LTD

Perovskite solar cell, preparation method thereof and photovoltaic product

The invention provides a perovskite solar cell, a preparation method thereof and a photovoltaic product. The perovskite solar cell comprises a conductive substrate, a first charge transport layer, a modified perovskite light absorption layer, a second charge transport layer and an electrode which are sequentially stacked, the modified perovskite light absorption layer contains a perovskite material and a composite additive, and the composite additive comprises potassium perfluorobutanesulfonate and potassium perfluorohexane sulfonate. According to the invention, potassium perfluorobutanesulfonate and potassium perfluorohexane sulfonate are used as additives, and the potassium perfluorobutanesulfonate and the potassium perfluorohexane sulfonate cooperate to passivate and jointly adjust defect concentration, so that phase degradation of perovskite is hindered, and the quality of the perovskite thin film is remarkably improved. Through the passivation strategy, the efficiency and the stability of the battery are greatly improved, and a foundation is laid for commercial production.
Owner:WUXI UTMOST LIGHT TECH CO LTD

Targeted oxygen-carrying and drug-carrying hollow gold nanosphere connected with photosensitizer and preparation method of targeted oxygen-carrying and drug-carrying hollow gold nanosphere

The invention belongs to the technical field of medical materials, and discloses a targeted oxygen-carrying and drug-carrying hollow gold nanosphere connected with a photosensitizer and a preparation method thereof. The preparation method comprises the following five steps: preparing hollow gold nano-spheres, coupling folic acid, conjugating Ce6, carrying Dox and carrying oxygen, so that the hollow gold nano-particles connected with a photosensitizer Ce6 and folic acid with a targeting effect are successfully loaded with oxygen-containing perfluorohexane and a chemotherapeutic drug doxorubicin. The invention provides an efficient and safe tumor oxygenation strategy, develops a tumor specific targeting nano artificial oxygen carrier, realizes tumor oxygen supply, and solves the problem of poor curative effects of chemotherapy and photodynamic therapy caused by oxygen deficit.
Owner:TIANJIN INST OF MEDICAL SCI (TIANJIN MEDICINE & HEALTH RES CENT)

Active transient thermal management module based on graphene composite material, control method and application

The invention discloses a graphene composite transient heat management module and method, efficient heat conduction is realized through cooperation of a three-dimensional porous heat conduction network and a gradient honeycomb, the three-dimensional porous heat conduction network is formed by compounding graphene, carbon nanotubes (CNTs) and / or metal nanoparticles, and an active cooling module comprises a thermoelectric cooler (TEC) and a micro fluid channel. A working medium in the microfluid channel is perfluorohexane and circulates through the piezoelectric micropump, the thermoelectric refrigeration sheet and the microfluid channel are combined to realize millisecond-level passive response and active cooling under the control of double thresholds, the flexible structure can be in curved surface fitting, the cost is reduced by half, and the device is suitable for high-heat-flow scenes such as high-power LEDs, GPUs and 5G equipment.
Owner:SHENZHEN YUNLU NEW ENERGY CO LTD

Ultrasound-responsive pickering emulsion and use thereof in the preparation of tumor treatment preparations

This invention discloses an ultrasound-responsive Pickering-like emulsion and its application in the preparation of tumor therapeutic agents, relating to the field of tumor therapeutic nanomaterials. The emulsion consists of oxygen-carrying perfluorohexane droplets and copper-coordinated 1 / 4-carboxyphenyl porphyrin nanoparticles, wherein the nanoparticles act as colloidal surfactants, armoring the surface of the perfluorohexane droplets to form a Pickering-like emulsion. The preparation method includes: coordinating 1 / 4-carboxyphenyl porphyrin with copper chloride and co-assembling it with Pluronic F127 to obtain FTC NPs; then emulsifying perfluorohexane with the FTC NPs to obtain PFTC EMs, which can be further oxygen-saturated to obtain an oxygen-carrying emulsion. Under ultrasound, the emulsion undergoes responsive disintegration and simultaneously releases oxygen and FTC NPs, which can both deplete glutathione and alleviate tumor hypoxia, and promote the generation of reactive oxygen species and Cu. + Induced copper death, thereby reshaping the tumor microenvironment and enhancing the synergistic antitumor effect of sonodynamics / copper death.
Owner:ZHEJIANG UNIV

Method for preparing and purifying perfluorohexane

The invention provides a novel process route for preparing perfluorohexane (C6F14), and the preparation method comprises the following steps: diluting fluorine gas with inert gas to obtain first mixed gas, and mixing hexafluoropropylene dimer (C6F12) with perfluorinated liquid to obtain first mixed liquid; the first mixed gas and the first mixed solution are treated through a microchannel reactor and then transferred into a reaction kettle, a product in the reaction kettle is collected, the product is separated, and the crude perfluorohexane product is obtained. The problems that in the prior art, the C6F14 preparation process is complex, and the conversion rate is low are solved. On the other hand, the invention discloses a purification method for obtaining a high-purity C6F14 finished product. The conversion rate and the purity of the perfluorohexane obtained by the scheme of the invention are obviously improved.
Owner:GUANGDONG HUATE GAS CO LTD

Lactic acid metabolism regulation nano preparation, preparation method and application

The invention relates to the field of biological medicine, in particular to a lactic acid metabolism regulation nano preparation, a preparation method and application thereof.The lactic acid metabolism regulation nano preparation contains an oxygen-enriched phase change agent, the oxygen-enriched phase change agent serves as a core, the outer side of the oxygen-enriched phase change agent is wrapped with lipidosome, the lipidosome is cRGD peptide modified lipidosome, the lipidosome is loaded with a GLUT-1 inhibitor, the GLUT-1 inhibitor is BAY-876, and the oxygen-enriched phase change agent serves as the core. The oxygen-enriched phase change agent is perfluorohexane. After the HIFU operation, the nano preparation can regulate lactic acid and reduce the generation of lactic acid, so that the problems that cells in a sublethal heat stress area undergo metabolic disorder and a large amount of lactic acid is generated after the HIFU operation are solved.
Owner:THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

Composite particles

Provided are composite particles in which an ammonia-generating compound is supported on a carrier, the composite particles being characterized in that: the carrier is at least one selected from the group consisting of silicon carbide, alumina, titania, silica, zirconia, ceria, silica alumina, calcia, magnesia, and carbon black; and the ammonia-generating compound is a compound that generates ammonia upon heating, is insoluble in perfluorohexane, and has a specific gravity smaller than the specific gravity of perfluorohexane at 20°C.
Owner:NISSHIN ENG +1

A filtration membrane and a method for producing the same

ActiveCN122321652BMeth-Filtration membrane
The application provides a filter membrane and a preparation method thereof, and the preparation method comprises the following steps: placing a porous filter membrane substrate in an environment containing plasma and a precursor, and performing plasma treatment to obtain the filter membrane; wherein the precursor comprises at least one of hexamethyldisiloxane, perfluorooctyltriethoxysilane, pentane, ethylene, toluene, perfluorohexane, styrene, divinylbenzene, hexamethyldisiloxane, tetramethylsilane, tetraethoxysilane, tetrafluoroethylene, hexafluoropropylene. The filter membrane prepared by the preparation method can significantly reduce the swelling rate in an organic solvent, and simultaneously improve the permeation flux, so that the precise molecular weight cut-off is realized.
Owner:CHINA UNIV OF PETROLEUM (BEIJING) +1

Method for the preparation of pulse laser-responsive micro-nanorobots for drug delivery

The application belongs to the technical field of micro robots, and particularly relates to a preparation method of a pulse laser responsive micro-nano robot for drug delivery, which comprises the following steps: S1, preparation of a micro-nano robot core layer: preparing perfluorohexane through high-energy ultrasonic mechanical emulsification; S2, assembly of a micro-nano robot functional layer: dispersing perfluorohexane droplets in deionized water, adding tetrachloropalladic acid for stirring, then adding ascorbic acid solution for a reduction reaction, and centrifugally collecting to obtain perfluorohexane droplets assembled with palladium nanoparticles; and S3, assembly of a micro-nano robot modification layer: dispersing the perfluorohexane droplets assembled with palladium nanoparticles in an alkaline solution with a pH value of 8.5, then dropwise adding a dopamine hydrochloride solution, stirring in air at 25 DEG C, and centrifugally collecting to obtain the micro-nano robot after assembly and modification. The preparation method is simple, has high repeatability and controllability, and is conducive to large-scale production and application.
Owner:CHONGQING UNIV

Non-invasive near-infrared light triggered gold-perfluorohexane photo-thermal cavitation nanoparticles as well as preparation method and application of non-invasive near-infrared light triggered gold-perfluorohexane photo-thermal cavitation nanoparticles

The invention belongs to the field of functional material synthesis, and particularly relates to a non-invasive near-infrared light triggered gold-perfluorohexane photo-thermal cavitation nano-particle and a preparation method and application of the non-invasive near-infrared light triggered gold-perfluorohexane photo-thermal cavitation nano-particle. The preparation method comprises the steps of fat cell targeting peptide solution preparation, gold nanoparticle preparation, perfluorohexane emulsion preparation, lipid membrane preparation, nanoparticle assembly and the like. The nano-particles are combined with fat cells through targeting peptides, near-infrared light triggers photothermal conversion of the gold nano-particles and phase change cavitation of perfluorohexane, the fat cells are synergistically destroyed to release lipid droplets, and the nano-particles have the advantages of non-invasiveness, high targeting property, no drug side effect and precise weight losing effect, and can be used for preparing weight losing products.
Owner:CHENGDU INTERGENO BIOTECHNOLOGY CO LTD

A method for degrading perfluorohexane sulfonic acid in wastewater based on ionizing radiation technology

ActiveCN119873950BWater/sewage treatment by irradiationWater contaminantsIonizing irradiationPerfluorohexanesulfonic acid
This invention provides a method for degrading perfluorohexanesulfonic acid (PFHA) in wastewater based on ionizing irradiation technology. The method includes: adding reagent A to wastewater containing PFHA, followed by ionizing irradiation treatment to reduce and defluorinate the PFHA in the wastewater. Hydrogen peroxide is then added to the defluorinated solution, followed by a second ionizing irradiation treatment to complete the deep decomposition and mineralization of PFHA in the wastewater. This invention has advantages such as simple process, mild conditions, high defluorination efficiency, good mineralization effect, and ease of scale-up. It can efficiently reduce, defluorinate, and mineralize PFHA in wastewater and is suitable for treating various wastewaters containing PFHA pollutants.
Owner:TSINGHUA UNIVERSITY +1