11results about How to "Guaranteed Features" patented technology

This invention discloses an APLN monoclonal antibody, its preparation method, and its applications. The APLN monoclonal antibody includes a light chain variable region and a heavy chain variable region. The amino acid sequence of the light chain variable region is shown in SEQ ID No:1, and the amino acid sequence of the heavy chain variable region is shown in SEQ ID No:2. The APLN monoclonal antibody is obtained by immunizing mice with APLN protein, followed by single-cell B-cell sorting and single-cell PCR. Utilizing advanced single-cell B-cell cloning technology combined with single-cell PCR, a novel APLN monoclonal antibody has been developed. The obtained antibody sequence is the result of natural affinity maturation screening by the in vivo immune system, requiring no additional humanization or in vitro affinity maturation steps. It retains the natural high affinity and specificity, and can directly obtain all-natural antibodies with high affinity and high specificity.

The invention discloses a floating foot structure for floating sleep-aiding equipment. The problems that existing equipment is insufficient in buoyancy, large in resistance, high in noise and inflexible in state switching are solved. The floating foot structure comprises a buoyancy tank, a floating foot body sleeved in the buoyancy tank, a guide mechanism between the buoyancy tank and the floating foot body, and a liquid adjusting adaptive part in the floating foot body; the floating foot body is in a big-end-down outline, and both buoyancy and sinking and floating sensitivity are considered. The guide mechanism is arranged to be a plurality of balls, a columnar rod or an anti-collision assembly, so that resistance is reduced and collision is prevented; the liquid adjusting adaptation part is matched with the external assembly to adjust the total mass of the floating foot body, and smooth floating / landing switching of the floating foot body is achieved. The invention further provides equipment applying the structure, and the equipment can be provided with a driving module and a balancing module to optimize the using effect. The structure is matched with a sleeping-aiding bed baby sleeping basket and the like, light, high in strength, capable of being optimized in a scene mode, low in noise, capable of saving energy, stable in movement and outstanding in practicability.

The invention belongs to the technical field of polymer composite materials and functional electrolyte materials, and relates to an interface covalently constructed MOF composite electrolyte film, and a preparation method and application thereof. The method comprises the following steps: preparing a polymer matrix formed by polymerizing imidazole zwitterionic monomers and a metal organic framework material; the preparation method comprises the following steps: sequentially adding a polymer matrix formed by polymerizing imidazole zwitterionic monomers, a metal organic framework material, an ionic liquid and a photoinitiator into a methanol solvent to obtain a precursor suspension; initiating free radical polymerization reaction of acrylate double bonds by the precursor suspension in a photo-initiation or thermal initiation mode to form an initial three-dimensional cross-linked network; and heating the initial three-dimensional cross-linked network to volatilize the methanol solvent, and cooling to room temperature to obtain the interface covalently constructed MOF composite electrolyte film. Through covalent bonding interface engineering design, the problems of poor dispersibility and weak interface bonding of MOF in a polymer matrix are solved. The obtained film has excellent mechanical properties and ionic conductivity.

This invention relates to a Cr and Br dual-element doped polyanionic sodium-ion battery cathode material, sodium iron phosphate pyrophosphate, its preparation method, and its application, belonging to the field of sodium-ion battery technology. The general chemical formula of the cathode material of this invention is: Na₄Fe₂O₃. 3‑x Cr x (PO4)2P2O7Br y Where 0 < x < 0.5, 0 < y < 0.7; the precursor wet gel is obtained through a sol-gel process, dried, and then sintered. This invention relates to a Cr- and Br-doped polyanionic sodium-ion battery cathode material, sodium iron phosphate pyrophosphate. The Cr dopant enhances bulk stability, while the gradient distribution of Br forms a fast ion conduction layer on the surface. The two elements together improve the rate capability and cycle performance of the sodium-ion battery. This provides a modification strategy of significant reference value for cathode materials that suffer from low discharge specific capacity and poor cycle performance at high rates due to electron conductance differences.

This invention discloses a bivalent anti-Vibrio parahaemolyticus nanobody, its preparation method, a self-sandwich ELISA kit, and a detection method. The aim is to provide a bivalent anti-Vibrio parahaemolyticus nanobody, kit, and detection method with high accuracy, specificity, and sensitivity for detecting Vibrio parahaemolyticus. The amino acid sequence of the bivalent anti-Vibrio parahaemolyticus nanobody is shown in SEQ ID NO.7. This invention belongs to the field of biodetection technology.

This invention provides a Cr2Se3 single crystal and its preparation method, relating to the field of crystal materials technology. The Cr2Se3 single crystal preparation method, from raw material proportioning and powder preparation to single crystal growth, involves coordinated steps to suppress impurity introduction and impurity phase formation, while simultaneously promoting ordered atomic arrangement and eliminating lattice vacancies and dislocations, resulting in a Cr2Se3 single crystal with good single-phase properties, high crystallinity, and extremely low defect density. The high-purity, low-defect single crystal structure ensures its semiconductor transport properties and antiferromagnetic order; it also eliminates interference from impurity scattering and lattice distortion, optimizing the magnetic field's control over the magnetic moments of Cr atoms, enabling the single crystal to exhibit a strong CMR effect approaching -100%. Furthermore, the coordinated steps ensure consistency in size, phase composition, and structural integrity of the prepared Cr2Se3 single crystal, significantly improving the success rate, process controllability, and repeatability.

This invention relates to the field of fluorescence sensing materials technology, specifically to a biporous cationic covalent organic framework material, its preparation method, a ratiometric fluorescent probe, and its applications. The unit cell parameters of the biporous cationic covalent organic framework material are: a = 72.3305 Å, b = 72.3305 Å, c = 3.7877 Å, α = β = 90.000°, γ = 120.000°; its structure is shown in Formula I. This invention utilizes the strong electrostatic interaction between the nanoscale pore wall ion sites of the biporous cationic covalent organic framework material and the charged groups of fluoroquinolone antibiotics, combined with a spatial matching effect, to achieve highly selective recognition of FQs.

The application discloses an epitaxial structure of a semiconductor device, a preparation method of the epitaxial structure and the semiconductor device, and the epitaxial structure comprises a substrate, a transition layer and a gallium nitride epitaxial layer; the transition layer is located on one side of the substrate; the gallium nitride epitaxial layer is located on a side, away from the substrate, of the transition layer; wherein the thickness X of the transition layer and the thickness Y of the gallium nitride epitaxial layer satisfy: Y=c-(X-b)*a; X+Y<c+b; in the formula, c represents an initial thickness reference value of the gallium nitride epitaxial layer, Y<c; b represents an initial thickness reference value of the transition layer, X>b; the units of X, Y, c and b are all nanometers; a is a first coefficient, and is unitless, 1<a<=10. The scheme can guarantee the performance of the device, reduce the thickness of the epitaxial structure of the device, reduce the cost, and improve the production capacity of a production line.

This invention discloses a semi-quantitative RT-LAMP method and kit for viral nucleic acid detection based on dispensed lyophilized microspheres and a multi-channel microfluidic chip. The method includes: designing two independent LAMP primer sets (P1 and P2) for each of the SARS-CoV-2 Omicron strain N gene, Zika virus NS5 gene, H1N1 influenza virus M1 gene, and H3N2 influenza virus NP gene; preparing two independent types of lyophilized microspheres by independently mixing RT-LAMP premix containing Bst DNA polymerase and other components with LAMP primer mixture and a lyophilization protectant; and using an N-channel microfluidic chip to perform serial dilutions and parallel RT-LAMP amplification of the same sample, determining the concentration of viral nucleic acid in the sample by the positive / negative inflection points of each channel. This invention is simple to operate, requires no equipment such as a real-time PCR instrument, and is suitable for rapid virus detection in various scenarios.

This application discloses a method for fabricating a thermoelectric device and the thermoelectric device itself. The method includes: polishing a first connecting surface of a target silicon-germanium alloy and a second connecting surface of a target electrode material; fabricating a target connecting layer based on a target connecting material, wherein the target connecting material includes silicon carbide or a silicon carbide-based multiphase ceramic; bonding the first connecting surface, the target connecting layer, and the second connecting surface; and holding the material at a preset temperature and pressure range for a preset time to connect the target silicon-germanium alloy and the target electrode material to fabricate the thermoelectric device. This application uses silicon carbide or a silicon carbide-based multiphase ceramic as the connecting layer. Utilizing its high stability and compatibility with the silicon-germanium alloy, it can alleviate joint cracking caused by stress mismatch. Simultaneously, by selecting transition metals and high-entropy alloys in the multiphase ceramic, it utilizes metallic bonding characteristics to ensure good conductivity, thereby reducing contact resistance and ensuring the functional characteristics of the thermoelectric device.