The invention relates to the field of animal and plant and plant application research (combination), particularly to a preparation process and method of serum for skin repairing. The serum comprises the following raw materials: a propolis extract, a honey extract, a royal jelly extract, beta-glucan, acetyl Hexapeptide-8, L-Carnosine, oligopeptide-32, oligopeptide-1, peony flower/leaf/root extract,aloe vera extract, carbomer, xanthan gum, a mung bean extract, a centellae herba extract, a plantain herb extract, a hyperforin perforatum extract, rosemary leaf water, imidazolidinyl urea, xylitol,capryloyl hydroxamic acid, glycerol, sodium hyaluronate, butanediol, and water. According to the invention, animal extracts are combined with plant extracts to prepare the skin care product having theeffects of repairing skin injuries, supplementing skin nutrition, improving skin blood circulation, updating skin cell regeneration, improving skin elasticity and softness, improving skin quality, removing skin yellow melanin and enabling skin to be white and bright.