103 results about "Nanocomposite hydrogels" patented technology

The invention provides a self-repairing and self-adhering nano composite hydrogel material as well as a preparation method and application thereof. The self-repairing and self-adhering nano composite hydrogel material provided by the invention comprises a boric acid derivative modified first monomer, a second monomer and a conductive filler. A macromolecular network formed by the two monomers generates crosslinking through reversible interaction so as to improve the mechanical strength of the hydrogel, and meanwhile, the hydrogel is endowed with reliable self-repairing performance; in addition, a macromolecular chain of the hydrogel contains more free active groups, and the hydrogel can be adhered to materials such as skin through reversible interaction among the groups. The doping of the conductive filler is also beneficial to improving the mechanical property, the conductivity and the sensing property of the hydrogel, so that a flexible wearable sensor assembled by the hydrogel can sensitively and stably monitor a human body motion signal and an electrophysiological signal.

The invention discloses multifunctional hydrogel for promoting healing of diabetic wounds and a preparation method of the multifunctional hydrogel. The multifunctional hydrogel is prepared from Ti3C2Tx-Ag, paeoniflorin (PF), a gel matrix oxidized konjac glucomannan (OKGM) solution and carboxymethyl chitosan (CMCS). The method comprises the following steps: mixing Ti3C2Tx powder with AgNO3 in deionized water, heating to boiling, adding a proper amount of a sodium citrate solution, reacting to obtain Ti3C2Tx-Ag (TA) powder, and mixing the powder with a paeoniflorin (PF) and oxidized konjac glucomannan (OKGM) solution and a carboxymethyl chitosan (CMCS) solution to prepare the KC-PF-TA hydrogel. The multifunctional hydrogel has excellent photo-thermal antibacterial performance, anti-inflammatory performance and angiogenesis promoting performance, shows a remarkable effect of promoting healing of diabetic wounds through the synergistic effect of Ti3C2Tx-Ag and paeoniflorin, and has good biocompatibility; the multifunctional nano-composite hydrogel disclosed by the invention has great application prospect and value in the field of wound repair materials.

The invention discloses a near-infrared responsive injectable MXene / fibroin / carboxymethyl chitosan / oxidized hyaluronic acid nano composite hydrogel SCO (at) M, and relates to the technical field of biomedical materials. The method disclosed by the invention comprises the following steps: 1) preparing an MXene single-layer nanosheet by adopting LiF-HCl in-situ HF etching; (2) modifying the fibroin through glycidyl methacrylate to obtain SF-MA; 3) oxidizing hyaluronic acid with sodium periodate to obtain oxidized hyaluronic acid OHA; (4) uniformly dispersing MXene in the SF-MA solution, and sequentially adding carboxymethyl chitosan CMCS and OHA, so as to prepare the injectable nano composite soft hydrogel with the shear thinning characteristic; and 5) through ultraviolet irradiation crosslinking, rapid in-situ curing of the hydrogel is realized, and the mechanical strength of the hydrogel is improved. The hydrogel provided by the invention has excellent injectability and mechanical property, has good photo-thermal antibacterial property, oxidation resistance and cell compatibility, can be used as a carrier of cells, medicines and bioactive substances in the field of biological medicines, and has a wide application prospect.

The invention discloses organic nano composite hydrogel as well as a preparation method and application of the organic nano composite hydrogel, and belongs to the technical field of biological medicine delivery. The polysaccharide-based nano prodrug in the composite hydrogel can be subjected to surface protonation under the stimulation of a tumor extracellular slightly acidic environment, so that cellular uptake is promoted, low-pH / high-concentration glutathione in tumor cells is responded, intracellular aggregation and controllable release of the nano drug are realized, the retention time of the drug in the cells is prolonged, and the bioavailability of the drug is improved. The technical effect of killing tumor cells through combined chemotherapy is achieved. According to the preparation method disclosed by the invention, the release of the polysaccharide-based nano prodrug from the hydrogel and the tissue infiltration capacity are accelerated by adopting fluorinated orthoester, the infiltration of the polysaccharide-based nano prodrug to cells is increased, and then the drug-loaded compound is encapsulated by using gellan gum, so that the slow-release effect of the polysaccharide-based nano prodrug is enhanced; therefore, the efficient enrichment of the medicine at the tumor part is realized.

The invention discloses nano-composite hydrogel based on active oxygen removal as well as a preparation method and application of the nano-composite hydrogel, and relates to the technical field of biomedicine. The nano composite hydrogel based on active oxygen removal comprises a three-dimensional network skeleton structure formed by cross-linking oxidized chondroitin sulfate and carboxymethyl chitosan, and melatonin-loaded mesoporous polydopamine nanoparticles are encapsulated in the three-dimensional network skeleton structure. According to the invention, a nano material is combined with a three-dimensional network skeleton structure of the hydrogel, a novel nano composite hydrogel is developed, and the nano composite hydrogel has self-healing ability, good biocompatibility, good mechanical properties and long-acting drug release ability; meanwhile, the melatonin is loaded into the nano-composite hydrogel to develop a medicine compound, the medicine activity and the treatment effect are better than those of the melatonin, inflammation and oxidative stress can be relieved more effectively, and symptoms can be improved more effectively.

The invention discloses a preparation method of recombinant collagen nano-composite hydrogel for repairing wounds infected by multiple drug-resistant bacteria, which comprises the following steps: binding copper porphyrin pi-pi on titanium carbide nanosheets to form MXene coated CuTCPP nanoparticles, and carrying out amidation reaction on 3-aminophenylboronic acid and recombinant collagen to obtain the recombinant collagen nano-composite hydrogel for repairing wounds infected by multiple drug-resistant bacteria. MXene coated CuTCPP is doped into a modified recombinant collagen system and mixed with a polyvinyl alcohol solution, and the recombinant collagen nano-composite hydrogel is prepared. The self-healing property endowed by the dynamic cross-linking characteristic of the phenylboronic acid ester bond in the composite hydrogel disclosed by the invention can be highly adapted to irregular wounds; the nano particles with the heterojunction structure can be combined with photothermal therapy and photodynamic therapy to efficiently sterilize wounds; the hydrogel has the antibacterial property and the property of promoting wound healing, and can comprehensively and efficiently treat wounds infected by multiple drug-resistant bacteria.

The invention provides nano-composite hydrogel based on Mg-MOFs (magnesium-metal organic frameworks), which is characterized in that hollow mesoporous silica nanoparticles (HMSNs) are used as a core of the nano-composite hydrogel, magnesium-gallic acid metal organic frameworks (Mg-MOFs) are used as a shell of the nano-composite hydrogel, and a core-shell nano-composite material HMMs is formed; carrying out amination treatment on the core-shell nano composite material HMMs, and loading naringin (Nar) to obtain a drug-loaded core-shell nano composite material (N-HMMs (at) Nar); and carrying out a cross-linking reaction on the drug-loaded core-shell nano composite material (N-HMMs (at) Nar), methacrylic acid gelatin and PEGDA (Polyethylene Glycol Diacrylate), so as to form the nano composite hydrogel. The N-HMMs (at) Nar (at) GP hydrogel prepared by the invention has great application potential in bone defect repair.

The invention relates to the technical field of composite hydrogel preparation, in particular to a nano composite hydrogel preparation process based on a microfluidic technology. The gel comprises the following components in parts by mass: 50-70 parts of a gel matrix, 5-9 parts of a nano enhancement system, 8-14 parts of a functional carrier, 3-6 parts of a dynamic response system, 4-7 parts of a hyaluronic acid-sulfhydrylated heparin compound and 0.5-1.5 parts of L-ascorbyl palmitate. Precise mixing and directional arrangement of all component materials on a micro-level are realized through a microfluidic technology, so that a nano reinforcing system and a functional carrier are uniformly distributed in a gel matrix, the synergistic effect of all the components is fully exerted, the mechanical property and the biological function of the gel are effectively improved, and the preparation method is suitable for industrial production. And quaternized chitosan nanofibers, a dynamic response system for responding to external environment change and a hyaluronic acid-sulfhydrylated heparin compound for promoting angiogenesis are introduced, so that the gel has the biological functions of resisting bacteria and promoting angiogenesis through a synergistic effect.

The invention belongs to the technical field of biological materials, and particularly relates to nano composite hydrogel as well as a preparation method and application thereof. In the preparation process of the hydrogel, preparation of gelatin hydrazide and preparation of pullulan oxidation are sequentially completed, then preparation of active component loaded PLGA nanoparticles and self-assembly coating with metal-polyphenol are completed, and finally, the metal-polyphenol coated PLGA nanoparticles are mixed with gelatin hydrazide and pullulan oxidation to form gel in situ. The hydrogel has the characteristics of injectability, self-healing, wet adhesion and the like, the metal-polyphenol layer has the effects of resisting inflammation, resisting oxidation and promoting angiogenesis and generates photo-thermal response to near infrared rays, on-demand controllable release of the drug-loaded nanoparticles is achieved, the composite hydrogel can improve the wound surface microenvironment, promote angiogenesis and inhibit inflammation and scar formation, and the drug-loaded nanoparticles can be applied to wound healing. The ointment is suitable for burns, scalds and various complex wounds.

This research indicates a new kind of bio-self-assembled nanocomposite hydrogel based on natural xanthan polymer and sodium montmorillonite nanoparticle in the field of polymers, which is modified by Triaminopropyl triethoxysilane. This process does not contain any chemical cross-linking agent and it also has been synthesized; this bio-self-assembled nanocomposite hydrogel aims to function as a removal of heavy metals from drinking water and wastewater because it has the property to absorb ions. The self-assembling hybrid nanocomposite hydrogel is composed of xanthan gum which is a natural polymer and sodium montmorillonite which is an unmodified clay nanoparticle with precursor triaminopropylene triethoxysilane and hydrolysis of the precursor to stabilize nanoparticles to increase the surface area absorbent matrix, abundant binding and absorption sites, improvement of swelling behavior; the increase of the absorption capacity of heavy metals in the absence of any crosslinking agent was designed and synthesized.

The present disclosure relates to a field of biomedical technology. Embodiments of the present disclosure provide a leonurine nanocomposite hydrogel and preparation method and application thereof, including: dissolving dopamine (DA) monomers and inducing oxidation and self-polymerization of the DA to obtain polydopamine (PDA) nanoparticles, grafting thiol polyethylene glycol folic acid (SH-PEG-FA) on a surface of the PDA nanoparticles to obtain folic acid polydopamine (FA-PDA) nanocarriers; loading a leonurine (Leon) using the FA-PDA nanocarriers of the step 1 to obtain FA-PDA@Leon; encapsulating the FA-PDA@Leon of the step 2 into a gel matrix to obtain gel@FA-PDA@Leon hydrogel.

The invention discloses composite hydrogel with a photo-thermal antibacterial effect and a preparation method of the composite hydrogel. The composite hydrogel is prepared from the following components: gold nanorods with a photo-thermal effect; silver nanoparticles grow on the surface of a gold nanorod through a reduction deposition method, and a silver-coated gold nanorod of a core-shell structure is formed; oxidized hyaluronic acid and carboxymethyl chitosan are subjected to Schiff base reaction and cross-linking to form a self-healing hydrogel matrix; the advantages of the Au-Ag-PEG nanoparticles and the hydrogel are combined, so that the Au-Ag-PEG hydrogel has an excellent antibacterial effect in vitro and in vivo; therefore, the nano composite hydrogel wound dressing has huge application potential in the aspect of treating infectious skin wounds.

The invention belongs to the technical field of biomedical materials, and discloses a preparation method of nano composite hydrogel and application of the nano composite hydrogel in acceleration of healing of diabetic wounds. The invention constructs the hydrogel based on the epsilon-polylysine grafted by the oxidized hyaluronic acid and the phenylboronic acid and the ZIF-8. Due to the existence of the dynamic Schiff base, the boric acid ester bond and the coordination bond, the hydrogel has ideal mechanical property, strong viscosity, injectability, self-healing property and pH / ROS responsiveness. Due to the existence of chlorogenic acid and zinc ions, the hydrogel regulates macrophage phenotypes, relieves oxidative stress and accelerates healing of diabetic wounds through an NF-kappa B / JAK-STAT signal channel.

The invention provides nano-composite hydrogel with double-load eye protection factors as well as a preparation method and application of the nano-composite hydrogel. Specifically, the invention provides a nano-composite hydrogel, which comprises zein nanoparticles loaded with xanthophyll, and zein nanoparticles loaded with xanthophyll, the raw materials comprise anthocyanin, caseinate and arabinoxylan; a glucolactone; and water. The nano-composite hydrogel disclosed by the invention can be used for simultaneously embedding, protecting and delivering the xanthophyll and the anthocyanin, and is very suitable for preparing functional foods for relieving asthenopia.

The present invention discloses a pH / GSH program-responsive photothermal nanocomposite hydrogel co-drug-carrying system and a preparation method and application thereof, and belongs to the field of anti-tumor materials. The nanocomposite hydrogel co-drug-carrying system of the present invention is a pH-sensitive chitosan hydrogel co-carrying GSH stimulus-responsive drug-carrying nanoparticles encapsulated by hyaluronic acid and indocyanine green. The drug-carrying nanoparticles encapsulate tyrosine kinase inhibitors, and the chitosan hydrogel is obtained by cross-linking chitosan with polyethylene glycol-4-formylbenzoic acid. The nanocomposite hydrogel is easy to administer in situ, and the photothermal conversion of indocyanine green under near-infrared light irradiation is used to accurately thermally ablate the primary tumor; at the same time, the drug-carrying nanoparticles escape from the gel, respond to the release of the loaded tyrosine kinase inhibitor by GSH in the tumor cells, and inhibit tumor recurrence and metastasis. The nanocomposite hydrogel can achieve chemotherapy-photothermal synergistic therapy, enhance the therapeutic effect on tumors and reduce toxic side effects.

The invention discloses traditional Chinese medicine nano hydrogel for treating recurrent oral ulceration as well as a preparation method and application of the traditional Chinese medicine nano hydrogel, and belongs to the technical field of medicines. According to the preparation method disclosed by the invention, the modified daochiSan is introduced into hydrogel prepared from sodium alginate and chitosan to prepare the modified daochiSan iron nano composite hydrogel (FeNPs at DaochiSan hydrogel), and the hydrogel has the characteristics of high mechanical strength, strong stability, high swelling ratio, long adhesion time, oxidation resistance, biocompatibility and the like; by improving the bioavailability, the stability, the targeting property and the controlled release property of the medicine, the compliance of a patient is improved, the treatment effect is improved, and a new way is provided for the inheritance and the application of the traditional modified Daochi powder.

The invention discloses nano composite hydrogel modified silica gel as well as a preparation method and application thereof. The method comprises the following steps: (1) preparing carbon nanoparticles; (2) preparing a polyvinyl alcohol aqueous solution and a pre-polymerized solution of carbon nanoparticles and hydrogel; (3) preparation of nano-composite hydrogel modified silica gel: adding the pre-polymerized liquid and silica gel into the polyvinyl alcohol aqueous solution under stirring, adding an initiator, carrying out hot bath, carrying out condensation reflux in an inert atmosphere for reaction, and then adding a polyvinyl alcohol cross-linking agent and an HCl aqueous solution for reaction; and after the reaction is finished, centrifugally washing and drying to obtain the nano-composite hydrogel modified silica gel. The nano-composite hydrogel modified silica gel has excellent hydrophilicity, can be used as a hydrophilic mode liquid chromatography filler, and has great development space and application potential in the field of chromatographic separation and analysis.

A nano-composite hydrogel for radiosensitization after breast-conserving surgery for breast cancer and a preparation method therefor. The nano-composite hydrogel comprises a hydrogel loaded with mesoporus gold nanoparticles M@AuNPs. The preparation method is as follows: The starting materials include a modified chitosan solution, a modified hyaluronic acid solution, and M@AuNPs. M@AuNPs are dispersed in the modified hyaluronic acid solution and the modified chitosan solution is isovolumetrically mixed with the modified hyaluronic acid solution to give the hydrogel. An injectable hydrogel encapsulating nanoparticles. The injectable hydrogel has a structure uniformly encapsulating outer-layer modified gold nanoparticles, and is capable of implementing immunotherapy by means of the targeted sustained-release of therapeutic drugs and meanwhile achieving ray energy accumulation due to the higher atomic number of the gold nanoparticles, thereby effectively killing tumor cells at the tumor bed position. The strategy effectively reduces the radiation dose in the whole breast radiotherapy, and is beneficial to protecting normal tissues of the breast outside the tumor bed.

The invention discloses a method for preparing an immobilized enzyme by using nano composite hydrogel and application of the immobilized enzyme, the composite hydrogel is adopted to immobilize the enzyme, negatively charged zymoprotein is enriched on a positively charged nanoparticle carrier through the charge effect, the physical acting force is increased, and a three-dimensional network structure is formed through an in-situ polymerization method; the carbonyl reductase or lipase is immobilized in the hydrogel, so that the pore volume, the specific surface area, the average pore size and the pore width of the immobilized enzyme are improved, the loading capacity of the enzyme is further improved, the maximum loading rate is 3422mg / g, and the problem that the immobilized enzyme is easy to leak by an embedding method is solved. The method is mild in reaction condition, and the stability and catalytic activity of the immobilized enzyme are improved.

The invention relates to the technical field of biological materials, and discloses a preparation method of novel antibacterial nano composite hydrogel for repairing diabetic oral ulcer. Comprising the following steps: grafting 2-formylphenylboronic acid on titanium carbide (MXene) nanosheets to form MXene (at) FPBA nanoparticles, carrying out an amidation reaction on lipoic acid and recombinant collagen to obtain modified recombinant collagen, doping the MXene (at) FPBA into the modified recombinant collagen system, and carrying out photo-crosslinking to obtain the novel antibacterial nano composite hydrogel. The hydrogel combines the strong anti-oxidation and anti-inflammatory capabilities of lipoic acid, does not need to add anti-inflammatory drugs, and also has good adhesiveness; the MXene (at) FPBA nano particles can be used for capturing bacteria and carrying out efficient sterilization; and the raw materials used by the material have biological safety. Therefore, the hydrogel has the antibacterial property and the anti-inflammatory function, and can comprehensively and efficiently manage and treat diabetic oral ulcer wounds.

The invention provides a device for detecting pesticide in water based on nano-composite hydrogel and a preparation method. The device comprises first hydrogel and second hydrogel which are attached to each other, first ITO conductive glass is attached to the side, away from the second hydrogel, of the first hydrogel, second ITO conductive glass is attached to the side, away from the first hydrogel, of the second hydrogel, and the first ITO conductive glass and the second ITO conductive glass are covered with ITO films; the ITO film is connected with a voltage detection unit through a wire, and the voltage detection unit is connected with a display; the wall surface of the porous structure in the first hydrogel is positively charged and has anion selectivity; the wall surface of the porous structure in the second hydrogel is negatively charged and has cation selectivity. According to the invention, the information of the pesticide in water can be judged by detecting the voltage signal by utilizing an ion diffusion migration mechanism, and the method has the advantages of high detection speed, portability, easiness in operation and the like.

The invention provides biological nano composite hydrogel as well as a preparation method and application thereof, and the preparation method of the biological nano composite hydrogel comprises the following steps: dissolving VVPS and beta-CD in a NaOH aqueous solution, heating to 60-63 DEG C, and stirring for more than 30 minutes until the VVPS and the beta-CD are completely dissolved; slowly adding PEGDGE into the solution, continuously stirring until the cross-linking agent is dissolved, raising the temperature to 65 DEG C or above, and reacting for 4 hours or above to form hydrogel; and performing swelling treatment on the hydrogel, drying, soaking in an ethanol water solution containing capsaicin for more than 48 hours, filtering, and performing freeze drying. The biological nano composite hydrogel prepared by the preparation method disclosed by the invention has good application in delivery of capsaicin and alleviation of type II diabetes mellitus.

The invention provides a preparation method of acacia gum nano-composite hydrogel. The preparation method comprises the following steps: S1, mixing an acacia gum aqueous solution with a free radical initiator, and then sequentially adding acrylonitrile, CuFe2O4 nanoparticles and a cross-linking agent into the mixture to obtain the acacia gum nano composite hydrogel. The acacia gum nano-composite hydrogel combines the characteristics of a natural polymer, a synthetic polymer and inorganic nanoparticles, and is an effective adsorbent for removing heavy metals in an aqueous solution, the prepared magnetic hydrogel is treated by hydroxylamine hydrochloride, so that a nitrile group is converted into an amidoxime group to serve as a bidentate ligand, and the adsorption capacity of the hydrogel is improved. The existence of CuFe2O4 in the acacia gum nano-composite hydrogel makes the recoverable magnetic hydrogel possible, the recoverable magnetic hydrogel can be easily removed from an aqueous solution and regenerated, and after three continuous cycles, the recoverable magnetic hydrogel still has high heavy metal adsorption capacity.

The present invention provides a preparation method for a nano-drug composite dynamic cross-linked hydrogel with curcumin / nitric oxide / photothermal synergistic antibacterial effect. The present invention uses copper salt to chelate curcumin to form first nanoparticles, and then uses polydopamine to coat the first nanoparticles to form nano-drug P Cur Sodium nitroprusside and sodium phytate were used as raw materials and nano-coprecipitation method was used to prepare second nanoparticles; polydopamine was then used to coat the second nanoparticles to prepare a core-shell structure nano drug P NO ; The nano drug P cur and P NO The nanocomposite hydrogel is mixed evenly with carboxymethyl chitosan and oxidized hyaluronic acid to form a nanocomposite dynamically cross-linked hydrogel. In addition to its significant antibacterial properties, the nanocomposite hydrogel of the present invention also has significant advantages such as high antibacterial efficacy, good biosafety, convenient preparation, and low cost. The present invention also combines drug, photothermal, and gas therapy in a single device, facilitating synergistic and precise bacterial elimination.

The application discloses a kind of low modulus high ductility super-retarding concrete, the concrete includes by weight ratio: cement 254~360 parts, fly ash 68~108 parts, slag powder 68~70 parts, 5~16mm gravel 352~393 parts, 16~25mm gravel 660~729 parts, medium sand 669~705 parts, rubber powder 20 parts, polystyrene plastic 15 parts, water 150 parts, water reducing agent 5.9~7.5 parts, super-retarding agent 3.1~4.0 parts, water-based polyurethane 15 parts, nano composite hydrogel 15 parts, polyolefin elastomer 5 parts, polypropylene fiber 1.0 part, can have higher toughness, lower elastic modulus, and can reach design requirement strength and durability, simultaneously, when practical application, first, a layer of low modulus high ductility super-retarding concrete is poured, then continue to pour ordinary concrete, combined with other anti-cracking measures, can effectively reduce the constraint degree of bottom plate to upper portion, prevent temperature cracks.

The present invention belongs to the technical field of hydrogel preparation, and specifically relates to a force-induced color-changing nanocomposite hydrogel, its preparation method and application. The force-induced color-changing nanocomposite hydrogel is composed of covalently cross-linked polyacrylamide and rod-shaped cellulose nanocrystals. Among them, polyacrylamide forms a gel matrix with a cross-linked network structure, and the rod-shaped cellulose nanocrystals are interspersed in the gel matrix and arranged in a chiral nematic structure; the pitch is 1.9 - 3.0 μm; the nanocomposite hydrogel is colorless and transparent under a pressure < 150 kPa, and under a pressure ≥ 150 kPa, the nanocomposite hydrogel presents visible structural colors. Compared with the current sensitive hydrogels, the nanocomposite hydrogel needs to be under the action of at least 150 kPa of pressure to present structural colors, which can meet the requirements of some special pressure sensing fields.

The invention belongs to the field of injectable conductive hydrogel, and discloses high-stability injectable conductive nano composite hydrogel and a preparation method thereof. The method comprises the following steps: pre-polymerizing a dopamine monomer by adopting a nano clay dispersion liquid in a weakly alkaline oxygen-containing environment to form a polydopamine functionalized PDA-LAP nanosheet, and introducing the polydopamine functionalized PDA-LAP nanosheet into dopamine grafted gelatin and a conductive high-molecular polymer poly (3, 4-ethylenedithiophene) / polystyrene sulfonate; the injectable conductive nano composite hydrogel GPLP is constructed based on the non-covalent bond supramolecular interaction. The GPLP hydrogel prepared by the invention has excellent shear thinning, self-repairing, tissue adhesion, stability, conductivity and biocompatibility, and has a huge application prospect in the fields of electrical stimulation therapy, tissue engineering and regenerative medicine.

The application relates to a sizing agent for rayon and a preparation method thereof, which comprises the following components in mass fractions: 900-1100 parts of methyl acrylate, 100-140 parts of acrylic acid, 110-150 parts of methyl methacrylate, 340-380 parts of acrylonitrile, 330-340 parts of ethanol, 2.5-3 parts of mercaptan, 130-150 parts of sodium dodecyl benzene sulfonate, 1.5-2.5 parts of whiting, 280-300 parts of smoothing agent, 18-20 parts of antistatic agent, 13-17 parts of bactericide, and the balance of water; and further comprising a nano composite hydrogel, wherein the nano composite hydrogel comprises L-arginine, silicotungstic acid, acrylic acid and a modified montmorillonite system. The application has the effects of improving the flexibility and wear resistance of the sizing agent for rayon.

The application discloses a temperature-sensitive nanocomposite hydrogel for extinguishing and preventing re-ignition of lithium iron phosphate batteries and a preparation method thereof, and relates to the technical field of battery extinguishing and re-ignition prevention. First, a phase change heat storage microcapsule material is prepared by taking a dodecahydrate sodium hydrogen phosphate solution, an alkali compound and an ethanol solution of tetraethyl orthosilicate as raw materials; then, polyphosphoric acid-amino acid polymer is prepared by adding arginine into an ethanol solution of polyphosphoric acid; finally, the temperature-sensitive nanocomposite hydrogel is prepared by adding the phase change heat storage microcapsule material and the polyphosphoric acid-amino acid polymer into a hydrophilic gel material. The temperature-sensitive nanocomposite hydrogel has the comprehensive advantages of efficient extinguishing, rapid cooling and persistent re-ignition prevention, and the temperature-sensitive nanocomposite hydrogel reduces economic losses caused by lithium ion battery fires by combining physical cooling, chemical inhibition and physical isolation.

This invention discloses a temperature- and pressure-sensitive, high-strength, and tough multifunctional nanocomposite hydrogel and its preparation method, belonging to the field of hydrogel technology. The invention first isolates tunicin from sea squirts and hydrolyzes it with acid to obtain sea squirt nanocellulose. Hydroxypropyl cellulose is dissolved in deionized water, sodium dodecyl sulfate is added, and the mixture is sonicated until dissolved. Then, octadecyl methacrylate, acrylamide, sea squirt nanocellulose suspension, and MXene / Ag nanosheet dispersion are added sequentially, and the mixture is mixed with an initiator. Emulsion polymerization is then performed to obtain the nanocomposite hydrogel product. The reaction disclosed in this invention is easy to operate and operates under mild conditions. Furthermore, the nanocomposite hydrogel prepared by the method disclosed in this invention exhibits high efficiency in multiple sensitivities (temperature and pressure), high strength, and excellent biocompatibility, showing broad application prospects in disease diagnosis and daily monitoring in the medical and pharmaceutical fields.