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270results about How to "Easy to prime" patented technology

Fluid dispenser

A method and apparatus for an automated biological reaction system is provided. In the processing of a biological reaction system, there is a need for consistently placing an amount of fluid on a slide. In order to accomplish this, several methods are used including a consistency pulse and a volume adjust means. Moreover, in order to reliably operate an automated biological reaction system, the dispenser must be reliable, easy to assemble and accurate. Among other things, in order to accomplish this, the dispense chamber is substantially in line with the reservoir chamber, the reservoir chamber piston is removed, and the flow of fluid through the dispenser is simplified. Further, in order to operate the automated biological reaction system more reliably, the system is designed in modular pieces with higher functions performed by a host device and the execution of the staining operations performed by remote devices. Also, to reliably catalog data which is used by the automated biological reaction system, data is loaded to a memory device, which in turn is used by the operator to update the operator's databases. The generation of the sequence of steps for the automated biological reaction device based on data loaded by the operator, including checks to determine the ability to complete the run, is provided.
Owner:VENTANA MEDICAL SYST INC

Perfused three-dimensional cell/tissue disease models

A system has been constructed that recapitulate the features of a capillary bed through normal human tissue. The system facilitates perfusion of three-dimensional (3D) cell monocultures and heterotypic cell co-cultures at the length scale of the capillary bed. A major feature is that the system can be utilized within a “multiwell plate” format amenable to high-throughput assays compatible with the type of robotics commonly used in pharmaceutical development. The system provides a means to conduct assays for toxicology and metabolism and as a model for human diseases such as hepatic diseases, including hepatitis, exposure-related pathologies, and cancer. Cancer applications include primary liver cancer as well as metastases. The system can also be used as a means of testing gene therapy approaches for treating disease and inborn genetic defects.
Owner:MASSACHUSETTS INST OF TECH +1

Fluid dispenser

A method and apparatus for an automated biological reaction system is provided. In the processing of a biological reaction system, there is a need for consistently placing an amount of fluid on a slide. In order to accomplish this, several methods are used including a consistency pulse and a volume adjust means. Moreover, in order to reliably operate an automated biological reaction system, the dispenser must be reliable, easy to assemble and accurate. Among other things, in order to accomplish this, the dispense chamber is substantially in line with the reservoir chamber, the reservoir chamber piston is removed, and the flow of fluid through the dispenser is simplified. Further, in order to operate the automated biological reaction system more reliably, the system is designed in modular pieces with higher functions performed by a host device and the execution of the staining operations performed by remote devices. Also, to reliably catalog data which is used by the automated biological reaction system, data is loaded to a memory device, which in turn is used by the operator to update the operator's databases. The generation of the sequence of steps for the automated biological reaction device based on data loaded by the operator, including checks to determine the ability to complete the run, is provided.
Owner:VENTANA MEDICAL SYST INC

Lancing device

A lancing device is used with a lancet for lancing body tissue to result in a wound for bleeding. An improved lancing device has a priming knob having a slanted priming notch rotatably connected to the lancing device about an axis of rotation generally parallel to a central axis of the lancing device and a strike path of a lancet carrier. Rotation, translation, or both rotation and translation of the priming knob allows a user to prime the lancing device.
Owner:AGAMATRIX INC

Perfused three-dimensional cell/tissue disease models

A system has been constructed that recapitulate the features of a capillary bed through normal human tissue. The system facilitates perfusion of three-dimensional (3D) cell monocultures and heterotypic cell co-cultures at the length scale of the capillary bed. A major feature is that the system can be utilized within a “multiwell plate” format amenable to high-throughput assays compatible with the type of robotics commonly used in pharmaceutical development. The system provides a means to conduct assays for toxicology and metabolism and as a model for human diseases such as hepatic diseases, including hepatitis, exposure-related pathologies, and cancer. Cancer applications include primary liver cancer as well as metastases. The system can also be used as a means of testing gene therapy approaches for treating disease and inborn genetic defects.
Owner:MASSACHUSETTS INST OF TECH +1

Method and apparatus for modifying pressure within a fluid dispenser

A method and apparatus for an automated biological reaction system is provided. In the processing of a biological reaction system, there is a need for consistently placing an amount of fluid on a slide. In order to accomplish this, several methods are used including a consistency pulse and a volume adjust means. Moreover, in order to reliably operate an automated biological reaction system, the dispenser must be reliable, easy to assemble and accurate. Among other things, in order to accomplish this, the dispense chamber is substantially in line with the reservoir chamber, the reservoir chamber piston is removed, and the flow of fluid through the dispenser is simplified. Further, in order to operate the automated biological reaction system more reliably, the system is designed in modular pieces with higher functions performed by a host device and the execution of the staining operations performed by remote devices. Also, to reliably catalog data which is used by the automated biological reaction system, data is loaded to a memory device, which in turn is used by the operator to update the operator's databases. The generation of the sequence of steps for the automated biological reaction device based on data loaded by the operator, including checks to determine the ability to complete the run, is provided.
Owner:VENTANA MEDICAL SYST INC

Method and apparatus for modifying pressure within a fluid dispenser

A method and apparatus for an automated biological reaction system is provided. In the processing of a biological reaction system, there is a need for consistently placing an amount of fluid on a slide. In order to accomplish this, several methods are used including a consistency pulse and a volume adjust means. Moreover, in order to reliably operate an automated biological reaction system, the dispenser must be reliable, easy to assemble and accurate. Among other things, in order to accomplish this, the dispense chamber is substantially in line with the reservoir chamber, the reservoir chamber piston is removed, and the flow of fluid through the dispenser is simplified. Further, in order to operate the automated biological reaction system more reliably, the system is designed in modular pieces with higher functions performed by a host device and the execution of the staining operations performed by remote devices. Also, to reliably catalog data which is used by the automated biological reaction system, data is loaded to a memory device, which in turn is used by the operator to update the operator's databases. The generation of the sequence of steps for the automated biological reaction device based on data loaded by the operator, including checks to determine the ability to complete the run, is provided.
Owner:VENTANA MEDICAL SYST INC

Terahertz radiation sensor and imaging system

This invention relates to apparatus and methods for sensing terahertz radiation, in particular over an area, and to terahertz radiation imaging systems. A terahertz radiation sensor, the sensor comprising an optical beam input to receive an optical probe beam, a detector to modulate said probe beam responsive to terahertz radiation, and a photosensitive detector to provide an output responsive to said probe beam modulation. The sensor being configured to provide a first optical path between said optical beam input and said electro-optic detector and to provide a second optical path between said electro-optic detector and said photosensitive detector, and wherein said sensor further comprises a polarizer, said polarizer being located in both said first and said second optical paths. We further describe imaging systems for use with such a probe.
Owner:CRAWLEY DAVID ALEXANDER

Retrograde plunger delivery system

Cannulas are provided for delivering therapeutic material to a treatment site. The cannula includes a cannula body with a plurality of openings at the distal end, including a longitudinal opening and a plurality of transverse openings that are axially spaced from each other. The cannula also includes a plunger that is configured to be slidably disposed within the cannula lumen. When the plunger is proximally displaced in the cannula lumen, the plunger seals the distal end and deflects the therapeutic material out the transverse openings. As the plunger is proximally displaced within the lumen, the therapeutic material is forced to perfuse out transverse openings located proximal of the plunger position. In one embodiment, the plunger includes an additional pliable sealable member. In another embodiment, the distal end of the cannula body may be implanted by separating the distal end from the cannula body.
Owner:BOSTON SCI SCIMED INC

Cushion with bladders running different pressurization modes inside and outside dynamically selected target bladder group

A responsive cushion system includes a pressure adjustment system and a cushion formed by an array of bladders coupled to the pressure adjustment system. At least two of the bladders are independent from one another such that that each can be independently pressurized and depressurized by the pressure adjustment system. A processor is coupled to the pressure adjustment system and a user interface, and the processor is operable to select a target group of one or more bladders according to data received via a communication interface. The processor is further operable to control the pressure adjustment system to adjust pressurization of bladders outside the target group according to a first pressurization mode, and control the pressure adjustment system to concurrently adjust pressurization of the target group of bladders according to a second, different pressurization mode. At least one of the first and second pressurization modes dynamically changes pressure over time.
Owner:1834958 ALBERTA INC

Terahertz radiation sensor and imaging system

This invention relates to apparatus and methods for sensing terahertz radiation, in particular over an area, and to terahertz radiation imaging systems.A terahertz radiation sensor, the sensor comprising an optical beam input to receive an optical probe beam, a detector to modulate said probe beam responsive to terahertz radiation, and a photosensitive detector to provide an output responsive to said probe beam modulation. The sensor being configured to provide a first optical path between said optical beam input and said electro-optic detector and to provide a second optical path between said electro-optic detector and said photosensitive detector, and wherein said sensor further comprises a polarizer, said polarizer being located in both said first and said second optical paths. We further describe imaging systems for use with such a probe.
Owner:CRAWLEY DAVID ALEXANDER

Inhaler

An inhaler (1) for the delivery of a dose of powdered medicament for inhalation by a user comprising a housing (2) containing a cylinder (5) defining a chamber (5a) and a piston (6) movably received in the cylinder to enable a user to generate a charge of compressed air in the chamber to entrain a dose when the charge is released, wherein the cylinder and the piston include co-operating means (8, 9) thereon operable to draw the piston into the cylinder to compress a charge of air in the chamber in response to rotation of the piston.
Owner:VECTURA LTD

Synchronization of repetitive therapeutic interventions

A medical device of the type used for assisting a user in manually delivering repetitive therapy to a patient (e.g., chest compressions or ventilations in cardiac resuscitation), the device comprising a feedback device configured to generate feedback cues to assist the user in timing the delivery of the repetitive therapy, at least one sensor or circuit element configured to detect actual delivery times, at which the user actually delivers the repetitive therapy, and a processor, memory, and associated circuitry configured to compare the actual delivery times to information representative of desired delivery times to determine cue times at which the feedback cues are generated by the feedback device.
Owner:ZOLL MEDICAL CORPORATION

Fluid pressure sensing chamber

A pressure sensing chamber having a tubing extension with a reduced diameter portion extending through the chamber. The tubing contains a plurality of ports so as to allow the purging of air from the chamber, but the ports are sized so that bubbles entering the tubing cannot easily flow into the chamber. The reduced diameter portion creates a pressure differential between the holes. This differential pressure creates flow through the chamber under high liquid flow and turbulent liquid flow events.
Owner:ALCON INC

Room-temperature self-repairing fiber-reinforced epoxy composite material and preparation method thereof

The invention discloses a room-temperature self-repairing fiber-reinforced epoxy composite material and a preparation method thereof. According to the method, a repairing agent is loaded in a capillary tube, and buried among fiber-reinforced epoxy composite material layers, and the repairing agent contains a certain amount of foaming agent. After being formed, the composite material is heated above the decomposition temperature of the foaming agent, so that the interior of the capillary tube produces positive pressure. When the material is damaged to cause the breakage of the capillary tube, the repairing agent can fast flow to a breakage surface and produce reaction under the promotion of pressure, thus rebinding cracks together and repairing the damage of the material. The material has the outstanding characteristics that the capillary tube can provide enough repairing agent, so that the material has higher repair efficiency; through the introduction of the foaming agent, the repairing agent in the capillary tube can be guaranteed to fast flow automatically when the material is damaged.
Owner:SUN YAT SEN UNIV

Fluid pressure sensing chamber

A pressure sensing chamber having a tubing extension extending through the chamber. The tubing contains a plurality of ports so as to allow the purging of air from the chamber, but the ports are sized so that bubbles entering the tubing cannot easily flow into the chamber.
Owner:ALCON INC

Fluid dispenser

A method and apparatus for an automated biological reaction system is provided. In the processing of a biological reaction system, there is a need for consistently placing an amount of fluid on a slide. In order to accomplish this, several methods are used including a consistency pulse and a volume adjust means. Moreover, in order to reliably operate an automated biological reaction system, the dispenser must be reliable, easy to assemble and accurate. Among other things, in order to accomplish this, the dispense chamber is substantially in line with the reservoir chamber, the reservoir chamber piston is removed, and the flow of fluid through the dispenser is simplified. Further, in order to operate the automated biological reaction system more reliably, the system is designed in modular pieces with higher functions performed by a host device and the execution of the staining operations performed by remote devices. Also, to reliably catalog data which is used by the automated biological reaction system, data is loaded to a memory device, which in turn is used by the operator to update the operator's databases. The generation of the sequence of steps for the automated biological reaction device based on data loaded by the operator, including checks to determine the ability to complete the run, is provided.
Owner:VENTANA MEDICAL SYST INC

Pulsation axial flow blood pump

An axial-flow pulse blood pump for the patient of acute heart failure and final-phase heart disease is composed of a stator consisting of windings and shell, and a rotor consisting of high-energy magnet and propulsion unit. Said propulsion unit comprises spiral rotor, central axle and three pairs of cylindrical magnets to form a sealed one-way spiral blood channel. The rotation speed of rotor is pulsed by changing the pulse width and frequency of voltage or current in stator.
Owner:张杰民 +1

Light composite external wall panel and manufacturing method thereof

The invention provides a lightweight composite external wall panel and preparing method, which is composed of fabric reinforced cement flat and loading layer, wherein the loading layer is steel net reinforced light aggregate concrete layer; the fabric reinforced cement flat is composed on each side; the thermal insulation material is filled in the hollow cavity. The preparing method comprises the following steps: A. putting the fabric reinforced cement flat in the mould two sides; B. places the steel net with thermal insulation material in the middle between two fabric reinforced cement flats; C. pouring the light aggregate concrete among two fabric reinforced cement flats and thermal insulation material; D. waiting the mould demoulding to generate lightweight composite external wall panel.
Owner:广州益群板业有限公司

Electric control scanning waveguide leaky-wave antenna based on liquid crystal

The invention provides an electric control scanning waveguide leaky-wave antenna based on liquid crystal, belongs to the technical field of microwave antenna engineering, and aims at solving problems that a conventional electric control scanning leaky-wave antenna based on a varactor and other conventional electrically controlled elements is difficult to work at a microwave high-frequency band, and existing liquid crystal electric control scanning leaky-wave antennas require the special design of a bias circuit. The electric control scanning waveguide leaky-wave antenna comprises a top part dielectric plate layer, a metal layer, an insulation paste layer, a liquid crystal layer and a bottom part waveguide slot. The metal layer is arranged at the lower surface of the top part dielectric plate layer. The metal layer has a leaky-wave structure with etching of periodic transverse seams. Equivalent series inductance of electromagnetic wave is enabled to be increased by the periodic transverse seams when electromagnetic wave is transmitted between the bottom part waveguide slot and the metal layer. The metal layer is provided with N periodic seam units. Seam unit spacing distance p is from lambdag / 2 to lambdag. The seams of the middle part are main radiation units. Seam length l of the main radiation unit is from lambdag / 4 to lambdag / 2. The former four and the latter four seams are auxiliary radiation units.
Owner:北京超材信息科技有限公司

Joint filling machine with joint clearing function

InactiveCN108060770AImprove stabilityFor subsequent perfusionBuilding repairsBrickSpiral blade
The invention discloses a joint filling machine with a joint clearing function. The joint filling machine comprises an annular frame. Symmetrical suction cups are distributed at the four corners of the annular frame, opposite sliding grooves are formed in the inner wall of the annular frame, and movable blocks are sleeved with the sliding grooves in an inlaid mode. Pouring cylinders are arranged on the left sides of the movable blocks, and handles are fixedly connected to the upper surfaces of the movable blocks. According to the joint filling machine, the suction cups and the annular frame are arranged, the annular frame is fixed through the suction cups, thus the stability of construction operation is better, and the construction effect is improved; through arrangement of an abrasion wheel, a brush roll and a scraping knife, hardened clay is crushed through the abrasion wheel, the clay is cleared away from brick joints through the scraping knife and the brush roll, the brick joints are thoroughly cleared, subsequent pouring of a joint filling agent is facilitated, and the construction effect is ensured; the pouring cylinders are arranged, spiral blade rolls are arranged in the pouring cylinders and conduct stirring and mixing on the joint filling agent, by comparing with manual stirring, the effect is better, the efficiency is higher, and meanwhile, the joint filling agent isextruded and discharged through the spiral blade rolls.
Owner:HENAN GAOSHENG ENTERPRISE MANAGEMENT CONSULTING CO LTD

Perfusion balloon angioplasty catheter

A balloon angioplasty catheter having a balloon head assembly carried at the distal end of an elongated catheter body. The balloon head assembly includes an inflatable balloon envelope and a perfusion lumen extending through the balloon envelope to provide a blood flow passage during inflation of the balloon envelope. The invention also encompasses embodiments having a collapsible guidewire lumen for increasing perfusion blood flow upon guidewire withdrawal. Also within the scope of the invention is a distally stepped down perfusion catheter, allowing for decreased distal cross section. In another preferred embodiment, the perfusion lumen is inflatable. In yet another embodiment, the guidewire lumen is external to the perfusion lumen.
Owner:BOSTON SCI SCIMED INC

Liquid crystal electrical control zero-crossing scanning leaky wave antenna based on comb-line waveguide

The invention discloses a liquid crystal electrical control zero-crossing scanning leaky wave antenna based on comb-line waveguide, which belongs to the technical field of microwave antenna construction. The problems that a conventional electrical control scanning leaky wave antenna based on a varactor and other traditional electric tuning elements difficultly works in a microwave high frequency band and the existing liquid crystal electrical control fixed-frequency scanning leaky wave antenna is difficult to realize zero-crossing scanning and requires a bias circuit which is specially designed are solved. The antenna provided by the invention comprises a top dielectric plate layer, a metal layer, a liquid crystal layer and a bottom waveguide groove. The metal layer is arranged between the top dielectric plate layer and the bottom waveguide groove. A longitudinal groove structure is arranged on the upper surface of a rectangular plate to form the bottom waveguide groove. The metal layer is in a comb-line structure. N periodic slit units are arranged between two columns of comb teeth on the comb-line structure. N periodic slit units comprise two groups of vertical slit columns and a group of transverse slit column. Through periodic transverse slits, the equivalent series inductance of electromagnetic waves spreading between the bottom waveguide groove and the metal layer is increased. Through periodic vertical slits, the equivalent parallel capacitance is increased.
Owner:北京超材信息科技有限公司

3D filter for prevention of stroke

InactiveCN107530177AEnough to bypass efficacyEasy to primeStentsHeart valvesProsthesisRadial compression
The present invention relates to implantable endoluminal prostheses and methods of using such devices in preventing clots migration to avoid ischemic strokes. The implantable endoluminal prosthesisissuitable for deployment from the aortic annulus to the aorta and comprises a self-expandable braided framework able to expand from a radially compressed state in a delivery configuration to a radiallyexpanded state, and a radially collapsible valve body comprising an impermeable material.The self-expandable braided framework isformed of braidedwires having a given diameter,and hasa proximal end configured to extend toward the heart and a distal end configured to extent toward away from the heart and extending along an axis.The braided framework comprises a main tubular body at the distal end of the self-expandable braided framework,a neck at the proximal end of the self-expandable braided framework, a transition portion extending between the proximal end of the main tubular body and the distal end of the neck. The main tubular body 3 and the neck comprisea lumen in a cylindrical form with a circular cross-section and a constant diameterrespectively, and the diameter of the main tubularbody is larger than the one of the neck. The main tubular body, theneck and thetransition portion consistof an integrated structure comprising plurality of layers of made of biocompatible material, being devoid of any impermeable cover layer, and forming a wall having a thickness. The valve body is placed within the lumen of the neck.
Owner:FRID MIND TECH

Casting light composite foam floating material and preparation method thereof

The invention relates to a casting light composite foam floating material and a preparation method thereof. The composite foam floating material consists of a component A and a component B, wherein the component A comprises an epoxy resin, an epoxy active diluent, a surfactant, a thixotropic agent, a silane coupling agent, a foaming agent and hollow glass beads; the component B comprises a curing agent and a catalyst. The invention aims to provide a casting light composite foam floating material suitable for a casting process. The casting light composite foam floating material has the characteristics of low material viscosity, high flowing and leveling properties, high pouring and penetrating properties. The casting light composite foam floating material is suitable for pouring gaps and complex cavity structures, so that the defect that a prefabricated solid buoyancy material cannot be poured is overcome, and the casting light composite foam floating material is convenient to use and wide in application range.
Owner:QINGDAO ADVANCED MARINE MATERIAL TECH

Electrofluid spraying device and method for printing three-dimensional biological scaffold

The invention discloses a device and method for printing a three-dimensional biological scaffold. The printing method comprises the following steps that an polycaprolactone (PCL) solution after beingmixed with glacial acetic acid evenly is added into a solution supplying system; the motion speed and path of a motion platform during printing are set through a motion control system, the distance between a spraying needle and a polished silicon crystal substrate is adjusted, and the solution injection rate is set; and a power supply is adjusted, and voltage is exerted between the spraying needleand a loading platform. The three-dimensional biological scaffold which is printed by the method and has various helical structure micro morphologies has higher strength, greater contact area and higher porosity, and thus is more favorable for cell adsorption during cell seeding and differentiation and multiplication during cell culture.
Owner:NAT UNIV OF SINGAPORE SUZHOU RES INST +1

Colloidal electrolyte and battery containing colloidal electrolyte

The present invention discloses a colloidal electrolyte, which comprises: solvent water; an electrolyte salt, wherein the electrolyte salt can be ionized in a solvent to obtain cation and anion, the cation comprises first metal ion and second metal ion, the first metal ion can be reversibly removed-embedded at the positive electrode during a charging-discharging process, the second metal ion is subjected to reduction deposition at the negative electrode during a charging process to form a second metal, the second metal is oxidized and dissolved during the discharging process to form the second metal ion, and the anion is selected from sulfate ions or chloride ions; a gelling agent silica, wherein the gelling agent silica accounts for 1-10% of the weight of the colloidal electrolyte; and an additive, wherein the additive comprises at least one selected from poly sodium styrene sulfonate, alkyl sulfonate and borate. According to the present invention, the colloidal electrolyte is convenient to pour, and the battery processing technology is simple.
Owner:POSITEC POWER TOOLS (SUZHOU) CO LTD +1

Manufacturing device and method of resin transparent concrete block

The invention discloses a manufacturing device and a method of a resin transparent concrete block, and belongs to the technical field of novel concrete materials. The device used by the method is characterized by comprising a light guide body prototype part, a mold separation piece, cushion plates and a surrounding mold, wherein the light guide body prototype part comprises connecting parts acting a connecting effect, and multiple light guide branches; all the light guide branches can be connected as a whole due to the existence of the connecting parts thereby facilitating demoulding of a silicone mould and facilitating concreting; the mold separation piece is a middle-hollowed rectangular sheet, so that the mold can be naturally divided into two parts of a top mold and a bottom mold, and contact surfaces of the top mold and the bottom mold are smooth and compact in connection; and the cushion plates are two wood plates with the same size to raise the mold separation piece to a needed height. The device can conveniently and quickly apply a mold turning method to manufacture the silicone mold so as to produce resin light guide bodies in batches, so that the production efficiency of resin transparent concrete is improved.
Owner:DALIAN UNIV OF TECH

Fluid pressure sensing chamber

A pressure sensing chamber having a tubing extension extending through the chamber. The tubing contains a plurality of ports so as to allow the purging of air from the chamber, but the ports are sized so that bubbles entering the tubing cannot easily flow into the chamber.
Owner:ALCON INC

Folding water-storing water-retaining water wall

The invention relates to a folding water-storing water-retaining water wall, comprising more than one water bag units; the water bag unit comprises a flexible water bag and more than two skeletons; the flexible water bag forms an enclosed water storage space; the inner wall of the flexible water bag is provided with a silica gel layer; the skeletons are arranged on the flexible water bag and tightly connected and fixed with the flexible water bag; the water bag unit is provided with a fixing device; a connecting ring is arranged on the skeletons of the two ends of the flexible water bag in the water bag unit; a connecting piece is arranged between the adjacent connecting rings on the adjacent water bag units; the water bag unit is provided with a locking device; the flexible water bag is provided with a water inlet and a water outlet; and a sealing device is arranged between the water bag units. The structure of the folding water-storing water-retaining water wall can fast build and dismantle the water-storing water-retaining water wall, is convenient to transport and carry and has reliable water retaining.
Owner:黄文勇
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