Nuclear reprogramming factor and induced pluripotent stem cells

a technology of nuclear reprogramming factor and induced pluripotent stem cells, which is applied in the direction of peptides, viruses/bacteriophages, and genetically modified cells, etc., can solve the problems of human embryo use, ethical controversies, and hinder the application of human es cells
US20090227032A1Inactive Publication Date: 2009-09-10KYOTO UNIV
98 Cites 214 Cited by

Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
KYOTO UNIV
Publication Date
2009-09-10
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells.
Need to check novelty before this filing date? Find Prior Art

Description

PRIOR RELATED APPLICATIONS

[0001] This application is a continuation-in-part of U.S. application Ser. No. 12 / 213,035, filed Jun. 13, 2008, which is a continuation-in-part of PCT / JP2006 / 324881, filed Dec. 6, 2006, which claims priority to Japanese Application No. 2005-359537, filed Dec. 13, 2005, and also claims priority to U.S. Provisional Application No. 61 / 001,108, filed Oct. 31, 2007, and U.S. Provisional Application No. 60 / 996,289, filed Nov. 9, 2007. The entire disclosures of each of the above-cited applications are considered as being part of this application and are expressly incorporated by reference herein in their entireties.FIELD OF THE INVENTION

[0002] The present invention relates to a nuclear reprogramming factor having an action of reprogramming a somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screen...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More