6 results about "Core shell nanocomposites" patented technology

The invention refers to hierarchical nanocomposites including layered materials supported on suitable carriers. In a preferential aspect of the invention, the layered materials consist of graphene and related materials. In a preferential aspect of the invention, the carrier consists of nanoparticles characterized by a Mohs hardness higher than that of the layered materials included in the hierarchical nanocomposite. These materials, which consist of “core” nanoparticles (the carrier) wrapped by layered systems (the “shell”) such as graphene, graphene oxide and other graphene and related materials (GRMs), are suitable precursors to obtain inks with water. The hierarchical “core-shell” nanocomposites are obtained by a preparation procedure including at least one “in situ” mechanical exfoliation step of the layered materials. The mechanical exfoliation step is carried out owing to a reciprocal friction process between the components of the precursor mixture, that incorporates both the precursors of the layered materials and those of the supporting “core” carriers. The materials are suitable to prepare inks where “core” nanoparticles act as carriers for the single / few-layered supported graphene or GRM.

This invention discloses a moisture-resistant core-shell nanocomposite material with hierarchical pores and its application in breath detection. The composite material comprises a microporous metal-organic framework (MOF) core and a hydrophobic mesoporous silica nanoparticle shell coating the surface of the MOF core. The MOF core encapsulates a colorimetric dye responsive to the gas analyte, forming a microporous-mesoporous hierarchical pore structure. This invention effectively blocks water molecules through the hydrophobic mesoporous silica shell, endowing the material with excellent resistance to moisture interference; simultaneously, the microporous MOF core enriches gas molecules, providing a rapid mass transfer channel for the mesoporous shell, and the hierarchical pore structure synergistically enhances detection sensitivity. This invention also provides a sensing array, a breath detection system, and a method incorporating the composite material. This invention can be used for breath detection in high humidity environments and has promising application prospects.

The present invention relates to an orally administrable complex having an average hydrated particle diameter of 10 nm to 100 nm and comprising: a core composed of metal or metal oxide-based nanoparticle(s); and a shell disposed as an acid-resistant barrier layer on the surface of the core and coated with polysaccharide crosslinked colloidal particles which form multi-point coordination bonds with metal ions on the surface of the core and have an average hydrated particle diameter of 2 nm to 8 nm and a surface charge of -20 mV to 0 mV. The polysaccharide crosslinked colloidal particles are characterized in that, in an aqueous solvent, (i) an -OH functional group of a monosaccharide, which is a building block of a linear polysaccharide, a branched polysaccharide, or a cyclic polysaccharide, is modified using a first crosslinking agent having an epoxide group, and (a) the functional group modified by the first crosslinking agent and a spatially adjacent -OH functional group are directly crosslinked and / or (b) two spatially adjacent functional groups modified by the first crosslinking agent are crosslinked intramolecularly and / or intermolecularly via a second crosslinking agent having two or more amine groups (-NH2) to form polysaccharide crosslinked particles, and (ii) the number of crosslinking agent-derived basic amine groups exposed on the surface is modified with a -COOH functional group so that the surface charge of the polysaccharide crosslinked colloidal particles is in the range of -20 mV to 0 mV. The orally administrable complex according to the present invention is a T2 MRI contrast agent that can be used as an active ingredient of a composition for diagnostic biliary and pancreatic imaging.

The invention discloses a microporous carbon-coated core-shell nano composite material, a preparation method and application, and relates to the technical field of lithium batteries, and the preparation method comprises the following steps: uniformly dispersing silicon powder and graphite in a solvent to form a core material suspension; dopamine hydrochloride and hydrogen peroxide are added into the nuclear material suspension, polymerization reaction is carried out at the temperature of 60-85 DEG C, composite slurry is obtained, and the ratio of the total mass of the silicon powder and the graphite to the mass of the dopamine hydrochloride is 1: (0.1-0.5); carrying out spray drying treatment on the composite slurry to obtain precursor powder; sintering the precursor powder at high temperature to obtain a microporous carbon coated core-shell nano composite material; the microporous carbon-coated silicon / graphite core-shell nano composite material is prepared by adopting a polydopamine in-situ polymerization technology initiated by hydrogen peroxide and combining a subsequent spray drying and carbonization process, and the material has good rate capability, cycling stability, charge-discharge efficiency and low interface impedance.

The invention discloses a near-infrared light response polydopamine-resveratrol core-shell nanocomposite as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials and nanomedicines.The near-infrared light response polydopamine-resveratrol core-shell nanocomposite is composed of an inner core and an outer shell, the inner core is composed of polydopamine, and the outer shell covers the surface of the inner core and is composed of resveratrol; the nano composite material can synergistically exert a photo-thermal therapy effect under near-infrared light irradiation, remove active oxygen and activate an AMPK signal channel. According to the invention, the photo-thermal treatment capability of polydopamine is combined with the drug activity of resveratrol, so that active oxygen can be synchronously removed, the mitochondrial homeostasis can be programmed and remodeled, the photo-thermal-drug synergistic effect under the response of near-infrared light is realized, the mitochondrial homeostasis is effectively remodeled, the AMPK signal channel is activated, and the drug activity of resveratrol is improved. Therefore, the energy metabolism and steady state balance of the cells are recovered, the reversal of cell senescence is finally realized, the revascularization is promoted, and the excessive inflammation is inhibited.

This invention discloses a core-shell nanocomposite material prepared by sacrificial template in situ growth and its application in promoting the healing of infected wounds. The present invention is the first to use ZnO2@ZIF-8 as an acid-responsive H2O2 release source to construct a ZnO2@Hemin-ZIF-8@PB composite nanomaterial. This material remains stable in a neutral environment, triggers H2O2 release in the infected microenvironment, and achieves efficient antibacterial and biofilm clearance through the synergistic effect of Hemin / PB-mediated chemical kinetics and Prussian blue (PB) photothermal effect. At the same time, this material can regulate the inflammatory response and promote angiogenesis, thereby accelerating the repair of infected wounds.