The invention discloses a chiral 1,2-diamine compound and a preparation method and application thereof. The molecular structure general formula of the chiral 1,2-diamine compound is shown as the general formula (I) in the specification. The preparation method of the chiral 1,2-diamine compound comprises the steps that an amine compound A and a nitroolefin compound B are added to a reaction system containing an n-heterocyclic carbine catalyst, an alkali reagent, a proton additive and a dewatering reagent for reacting and other steps. The chiral 1,2-diamine compound comprises chiral quaternary carbon atoms containing electrondrawing groups and amino groups, and can be widely used for synthesizing drug intermediates, especially heterocyclic ring structure compounds, and preparing functional materials. The preparation method is simple in process and low in requirement for reaction conditions, the reaction process is safe and controllable, the atom utilization rate and production efficiency are high, meanwhile, the enantioselectivity of products is efficiently guaranteed, and the environment pollution pressure of the methodology is low through the introduction of the small organic molecule asymmetric catalysis concept.