Antibacterial black phosphorus nanometer material and preparation method thereof

Abstract

The invention discloses an amino ligand surface modified black phosphorus nanometer material and a preparation method thereof, and applications of the amino ligand surface modified black phosphorus nanometer material in antibacterial field. According to the present invention, the antibacterial amino group in the sulfanilamide-based group is introduced into the surface of the nanometer material soas to provide the antibacterial performances of wide antibacterial spectrum, high sterilization efficiency and less drug resistance for the nanometer material; the preparation method has characteristics of simple and easy operation, high yield, good reproducibility, low cost and large-scale production; the use of the black phosphorus nanometer material does not cause secondary pollution to the environment; and the modified two-dimensional black phosphorus nanometer material can significantly inhibit the growth of gram-negative bacteria and gram-positive bacteria, and has excellent antibacterial effect so as to provide great application potential in the field of medical materials.

Description

technical field [0001] The invention relates to the field of modified nanomaterials, in particular to an amino ligand-modified black phosphorus nanomaterial, its preparation method and its application in the antibacterial field. Background technique [0002] As an emerging class of ultrathin nanomaterials, two-dimensional (2D) nanomaterials have shown high biocompatibility and wide potential for biomedical applications due to their unique structural characteristics and physical and chemical properties. Two-dimensional nanomaterials are the thinnest nanomaterials known so far. The low-dimensional nanostructures enable them to have ultra-high specific surface area and biological reactivity, as well as a broad optical response band. Nowadays, two-dimensional nanomaterials have been explored for various biomedical applications. Such as drug loading and delivery, contrast imaging of target areas in vivo, cancer diagnosis, photothermal therapy, etc. [0003] At present, the rese...

AI Technical Summary

Problems solved by technology

[0007] ①The modification process is complex and the yield is low, making it difficult to achieve large-scale production;

[0008] ②The cost of the modifier used is high, the modification effect is not ideal, and the biocompatibility is poor;

[0009] ③Modification technology does not have the ability to improve the antibacterial effect of black phosphorus nanomaterials

There are relatively few studies on the metal complexes of sulfonamides and their antibacterial activities

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