9 results about "Sulfaguanidine" patented technology

The invention discloses a sulfaguanidine modified inorganic tin-based perovskite light-emitting diode and a preparation method thereof, and belongs to the field of luminescent material preparation, the preparation method comprises the following steps: preparing a perovskite precursor solution which comprises cesium iodide, stannous iodide, sulfaguanidine and an organic solvent; applying the perovskite precursor solution to a substrate to form a wet film; carrying out annealing treatment on the wet film so as to form a perovskite light-emitting layer containing CsSnI3 perovskite and sulfaguanidine; a hole transport layer is formed on an anode conductive substrate, and a perovskite light-emitting layer is adopted on the hole transport layer; and sequentially forming an electron transport layer, an electron injection layer and a cathode electrode on the perovskite light-emitting layer. The process is simple and suitable for popularization and application.

The invention belongs to the technical field of organic synthesis, and particularly relates to a preparation method of sulfaguanidine. The invention provides a preparation method of sulfaguanidine, which comprises the following steps: mixing p-acetamidobenzene sulfonyl chloride, guanidine salt, strong base and ketone solvent for the first time, and then carrying out condensation reaction to obtain sulfaguanidine; mixing acetylsulfaguanidine with water for the second time, then adjusting the pH value to 8-9, and adding amide hydrolase for hydrolysis to obtain sulfaguanidine. According to the preparation method provided by the invention, a biological enzyme method is introduced for hydrolysis, so that the hydrolysis efficiency is high, the product conversion rate is high, the enzyme can be repeatedly recycled, the mother liquor is simple in component, can be directly recycled and reused, is simple to treat, and does not cause pressure to environmental protection; the raw materials are cheap and easy to obtain, the preparation cost is low, the reaction conditions are mild, the operation is simple and convenient, and industrial safe production is facilitated; the sulfaguanidine prepared by the preparation method provided by the invention has relatively high purity and relatively high yield.

The invention belongs to the technical field of photoelectric materials and devices, and particularly relates to a perovskite light-emitting-photovoltaic dual-function device and a preparation method thereof. The preparation method comprises the following steps: sequentially preparing an electron transport layer, a perovskite light-emitting-photovoltaic active layer, a hole transport layer and a top electrode on a transparent conductive substrate; the method is characterized in that when the perovskite light-emitting-photovoltaic active layer is prepared, specific functional molecules (such as beta-alanine, 5-amino valeric acid, phenylethylamine iodide, sulfaguanidine and the like) are introduced into a perovskite precursor to cooperatively regulate and control crystallization kinetics of perovskite, defects are passivated, and the perovskite light-emitting-photovoltaic active layer is prepared. And a microstructure (such as an embedded submicron cavity or a vertical single-layer crystal grain) which is beneficial to light management and carrier bidirectional transmission is guided to be formed. The device manufactured by the method can work as a high-efficiency light-emitting diode (EQEgt, 25%) and also can work as a high-efficiency solar cell (PCEgt, 15%), bidirectional high performance of optical-electric conversion is realized, and an effective scheme is provided for developing a novel integrated optoelectronic system.

Disclosed is a synthetic method of sulfamerazine, relating to the technical field of drug preparation. Acetone and methyl formate are used as initial raw materials, and subjected to condensation reaction to obtain a compound 2; the compound 2 is subjected to addition reaction in a medium of methyl hydrogen sulfate to obtain a compound 3; the compound 3 is subjected to cyclization reaction in a medium of sulfaguanidine to obtain a compound 4; and the compound 4 is subjected to acidification in an acidic medium to obtain the sulfamerazine.

The invention discloses application of sulfaguanidine in preparation of a medicine for treating melanoma, and relates to the technical field of biological medicines. Specifically, the invention provides application of at least one of sulfaguanidine, pharmaceutically acceptable salt of sulfaguanidine, stereoisomer of sulfaguanidine, solvate of sulfaguanidine and polymorphic substance of sulfaguanidine in preparation of drugs for treating melanoma. In the invention, the sulfaguanidine can inhibit proliferation, migration and invasion of melanoma cells, and can significantly inhibit tumor growth of melanoma in an animal model. Based on the action mechanism, the sulfaguanidine can be used as a novel candidate drug for treating the melanoma, is used for treating the melanoma, and provides a new safe and effective drug choice for clinical treatment of the melanoma.

The invention relates to the technical field of materials, and discloses a bamboo-based composite material and a preparation method thereof.The bamboo-based composite material is prepared by fully banburying and mixing bamboo powder and polypropylene, then continuing to add modified sulfaguanidine and modified benzoxazine, banburying for 8-10 min at the temperature of 175-180 DEG C, placing the banburying material on a mold of the corresponding specification, conducting hot pressing for 8 min at the temperature of 180 DEG C and the pressure of 12 MPa, and conducting extrusion molding to obtain the bamboo-based composite material. And then cooling to room temperature to obtain the bamboo-based composite material. The bamboo-based composite material disclosed by the invention has relatively good flame-retardant and tensile effects.

The application provides a preparation method of a hybrid perovskite solar cell passivated by sulfaguanidine and 1,3-propanediamine hydroiodide, and relates to the technical field of perovskite solar cells. The material is used for passivating the PIN type structure hybrid perovskite solar cell passivation layer. After the preparation of the hybrid perovskite thin film is completed, a certain concentration of mixed passivation molecule solution is dynamically spin-coated on the surface. The passivation molecule is sulfaguanidine and 1,3-propanediamine hydroiodide. By mixing sulfaguanidine and 1,3-propanediamine hydroiodide in a certain proportion, the solution spin-coating method is used to spin-coat on the surface of the perovskite light-absorbing layer. Based on the characteristics of chemical passivation and field effect passivation, the method can reduce the surface defects of the hybrid perovskite thin film, promote the extraction of carriers, inhibit non-radiative recombination, and improve the photoelectric conversion efficiency of the hybrid perovskite solar cell.

This invention belongs to the field of organic synthesis technology, specifically disclosing a bromoisoxazole compound and its synthesis and application. Compared with existing technologies that require the use of precious metal catalysts, additional oxidants, and high temperatures of 100°C, this process is the first to use trifluoroacetic acid (TFA) as a promoter, achieving efficient conversion in a mild air atmosphere of 28-60°C. This not only avoids the use of expensive metals and the risk of environmental pollution, but also has the advantages of inexpensive and readily available raw materials, short reaction time of only 4-12 hours, and a yield of up to 94%, showing significant industrialization advantages. Experimental data confirm that this series of compounds exhibits excellent biological activity, and its inhibitory effect on Staphylococcus aureus and Vibrio parahaemolyticus is significantly better than that of commercially available drugs sulfadiazine and sulfaguanidine. It has outstanding technological progress and broad market application prospects in the fields of developing new antibacterial drugs and food preservation.

The invention relates to the technical field of cross-linked polyolefin power cables, and discloses a weather-proof flame-retardant cross-linked polyolefin power cable and a preparation method thereof. Comprising the following operation steps: step 1, combining N single cable cores, coating an alkali-free glass fiber tape, and filling a modified lignin flame-retardant material; obtaining a power cable A; and 2, premixing a cross-linked polyolefin material, melting, extruding, and coating the surface of the power cable A with the cross-linked polyolefin material to form an outer sheath, so as to obtain the cross-linked polyolefin power cable. In the scheme, lignin is modified by short-chain amine and dodecylamine long-chain amine to realize compatibility matching of lignin and polyolefin, aminated lignin is crosslinked with sulfaguanidine and polyethyleneimine through 4, 4-biphenyldicarboxaldehyde, DOPO is introduced to obtain a lignin composite flame retardant, and the lignin composite flame retardant is mixed with different flame retardants for use, so that flame retardance and weather resistance are improved.