How to Sulfaguanidine?

Method for producing L-ornithine by microorganism fermentation,L-leucine high-yield bacterium and fermentation method using the same for L-leucine production,Streptomyces sp. for producing epsilon-polylysine and application of streptomyces sp.,Process for producing sulfadimidine,Bio-based antibacterial coating and preparation method thereof

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32 results about "Sulfaguanidine" patented technology

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Sulfaguanidine is a sulfonamide.

Method for producing L-ornithine by microorganism fermentation

InactiveCN101323866AFast acid productionImprove sugar conversion rateBacteriaMicroorganism based processesSolubilityChemical treatment

The invention provides a method for producing L-ornithine by microbial fermentation, namely, using Corynebacterium glutamate to obtain the strains of CS-189(cit<(-)>+SG<r>) by chemical treatment, and obtain the L-ornithine hydrochloride by fermentation, culture solution micro-filtration by a ceramic membrane, ion exchange resin and extraction by a hydrothermal crystallization method with decompression concentration. The strains used in the method are auxotrophy resistant to sulfaguanidine, which significantly enhances acid yield by fermentation. Meanwhile, aiming at the problem that the solubility of the L-ornithine hydrochloride in water is extremely difficult, the hydrothermal crystallization method is adopted to obtain better extraction rate under the condition that flammable and explosive alcohol is not used. The method simplifies processes and reduces extraction cost.

Method for producing L-ornithine by microorganism fermentation

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Owner:上海聚瑞生物技术有限公司

L-leucine high-yield bacterium and fermentation method using the same for L-leucine production

ActiveCN1702168AHas industrial practical valueBacteriaFermentationNitrosoguanidinesMicrobiology

It is an L-leucine high-yield bacterium and the production of L-leucine with invoice method, belonging to biological engineering field. The invented bacterial is a corynebacterium glutamicum JH-27, using corynebacterium glutamicum ATCC13032 as starting strain, mutagenizing separately with diethyl sulfate, nitrosoguanidine and ultraviolet, adding separately analogue of branched chain amino acid into minimum medium and sulfaguanidine into complete medium and breeding to prepare, being an L-leucine high-yield bacterium resistant sulfaguanidine and branched chain amino acid, compared with starting strain, producing L-leucine with the strain and invoice method, it expresses the ability of accumulation of highly qualified L-leucine. Shaking flask and culturing JH-27 for 60 hours, the yield of L-leucine is 30-32 g / l. Fermenting in fermenter of 5L for 55 hours, the yield of L-leucine is 40g / l.

L-leucine high-yield bacterium and fermentation method using the same for L-leucine production

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Owner:WUXI JINGHAI AMINO ACID

Streptomyces sp. for producing epsilon-polylysine and application of streptomyces sp.

ActiveCN110656065AImprove synthesis abilityIncrease productivityBacteriaMicroorganism based processesBiotechnologySulfanilamide

The invention discloses streptomyces sp. for producing epsilon-polylysine and an application of the streptomyces sp., and belongs to the field of biotechnology. A streptomyces albulus (streptomyces albulus) M-Z18 bacterial strain is preserved in the China General Microbiological Culture Collection Center, and the preservation number is CGMCC NO: M 2019589. The streptomyces albulus M-Z18 bacterialstrain can quickly grow on a culture medium using succinic acid as a carbon source, and has the capacity for high efficiency synthesis of epsilon-polylysine having sulfaguanidine resistance. The bacterial strain is subjected to fed-batch fermentation under a pH impact strategy, the accumulation concentration of the epsilon-polylysine can achieve 54.7g / L, the production efficiency can achieve 6.83g / L / d, and the streptomyces sp. is an epsilon-polylysine industrial production bacterial strain having great potential.

Streptomyces sp. for producing epsilon-polylysine and application of streptomyces sp.

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Owner:JIANGNAN UNIV

Process for producing sulfadimidine

InactiveCN102304093AQuality assuranceAchieve a neutralizing effectOrganic chemistrySulfanilamideSolvent

The invention relates to a process for producing sulfadimidine. Sulfaguanidine and acetylacetone are taken as raw materials; and the process comprises the following steps of: 1, performing condensation reaction to obtain a wet product of sulfadimidine; 2, washing with hot water to obtain a wet product of sulfadimidine, and removing other inclusions in a reaction solvent; 3, adding active carbon and caustic soda liquid into the washed sulfadimidine and performing alkali dissolution decoloration; 4, neutralizing caustic soda liquid brought by the decolored sulfadimidine by using an acid solvent, and crystallizing; and 5, separating out crystallized sulfadimidine by adopting a centrifugal analysis method, and drying to obtain a finished product. The process is characterized in that: in the neutralizing and crystallizing step, the acid solvent neutralization is hydrochloric acid neutralization. In the whole chemical production, hydrochloric acid is taken as a byproduct and can be recycled massively; and the hydrochloric acid replaces the conventional acetic acid neutralization solvent, which is more economic, and the quality of the obtained product is improved.

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Owner:SUZHOU WUGAN PHARMA

Bio-based antibacterial coating and preparation method thereof

ActiveCN109762447AGood antibacterial effectStable chemical propertiesAntifouling/underwater paintsPaints with biocidesEpoxyEmulsion

The invention discloses bio-based antibacterial coating and a preparation method thereof. The bio-based antibacterial coating is characterized by being prepared from the following components: an antibacterial macromolecule, waterborne epoxy emulsion, a de-foaming agent, an antioxidant, a waterborne curing agent and de-ionized water, wherein the antibacterial macromolecule is prepared through covalent bonding of sulfaguanidine, DL-tartaric acid and glycitin; then the antibacterial macromolecule is grafted on an epoxy resin matrix to form the bio-based antibacterial coating. The bio-based antibacterial coating prepared by the method integrates sterilization and bacterium inhibition and has relatively good antibacterial performance, stable chemical performance and relatively good heat-resisting performance; and the defect that a coating layer becomes invalid, caused by a series of problems of poor heat-resisting performance of traditional bio-based antibacterial coating, can be overcome.

Bio-based antibacterial coating and preparation method thereof

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Owner:SHENYANG SHUNFENG IND GRP CO LTD

Method for producing epsilon-poly-L-lysine by reflux technique

InactiveCN101078021BHigh yieldReduce pollutionBacteriaMicroorganism based processesLiquid wasteResist

This invention refer to a method that using backstreaming technology to produce epsilon -poly-L-diaminocaproic acid. It uses blanc Streptomyces that screened from soil to fermentepsilon -poly-L-diaminocaproic acid[resist to S-(2-aminoethyl)-L-cysteine(abbreviate AEC below), Glycine, sulfaguanidine],then make the penetrated liquid from later stage of extracted procession by periodic duty,to fermentepsilon -poly-L-diaminocaproic acid; the penetrated liquid from later stage of extracted procession can be used for next elution. Decolorize the broth by negion exchange resin. This invention has changed the procedure of producing technology.Not only raise the yield ofepsilon -poly-L-diaminocaproic acid, save cost, but also reduce exhaustion of ferment liquid waste and hydrochloric acid liquid waste in elution, lessen environmental pollution; The decolor effect is enhanced and the lose is reduced becouse of decoloring the broth by negion exchange resin.

Method for producing epsilon-poly-L-lysine by reflux technique

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Owner:TIANJIN UNIV OF SCI & TECH

Corrosion and scale inhibition fountain solution and preparation method thereof

InactiveCN104085220AReduce maintenance costsGood anti-scaling and anti-corrosion effectPrinting pre-treatmentSodium lactateSucrose

The invention discloses a corrosion and scale inhibition fountain solution. The corrosion and scale inhibition fountain solution is characterized by being composed of the following raw materials, by weight, 2-10 parts of sucrose ester, 1-2 parts of liquid paraffin, 2-8 parts of lauramidopropyl hydroxy sulfoBetaine, 1-6 parts of sodium lauryl diphenyl ether disulfonate, 0.5-1.5 parts of dodecyldimethylamine oxide, 1-3 parts of zinc sulfate, 1-2 parts of sulfaguanidine, 0.5-1.5 parts of polyaspartic acid, 1-2 parts of polyepoxysuccinic acid, 0.5-1 part of isothiazolinone, 1-2 parts of sodium lactate, 5-10 additives and 30-50 parts of water. The corrosion and scale inhibition fountain solution has good scale inhibition and corrosion protection effects, lowers maintenance cost of a printing system, is low in ink consumption amount and good in printing effect, and meets the requirements of environmental protection and energy saving.

Corrosion and scale inhibition fountain solution and preparation method thereof

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Owner:ANHUI SOYA DECORATIVE MATERIALS

Detection method for malachite green in aquatic products

ActiveCN109507126ARecognizableEnrichmentColor/spectral properties measurementsMalachite greenMalachite green stain

The invention discloses a detection method for malachite green in aquatic products. The detection method comprises experiment steps of preparing a magnetic molecularly imprinted polymer, establishinga method based on an aptamer and ferroferric oxide mimic enzyme catalysis and the like. According to the detection method, firstly, a dopamine polymerization method is used for preparing a malachite green (MG) magnetic molecularly imprinted polymer (MG-MMIPs); trace MG in a sample is adsorbed by utilizing the MG-MMIPs, so that the aims of enriching a target object and removing a complicated mediumare realized; then after enriched MG is desorbed, a detection method of the aptamer and ferroferric oxide mimic enzyme catalysis is used for detecting. The method has the sensitivity of 5 nmol L<-1>and the lowest detection limit reaches 3.6 nmol L<-1>. A specific experiment aiming at two structural analogues (including brilliant green and crystal violet) of MG and other bacteriostatic drugs (including sulfaguanidine, sulphanilamide, oxytetracycline hydrochloride and chloramphenicol) shows that the method has good selectivity in MG detection.

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Owner:JIMEI UNIV

Aerosol spray for dry cleaning of woolen clothes and preparation method of aerosol spray

ActiveCN103468416AEasy maintenanceGood decontamination effectOrganic detergent compounding agentsSurface-active detergent compositionsSpermacetiSulfanilamide

The invention relates to an aerosol spray for dry cleaning of woolen clothes and a preparation method of the aerosol spray. The aerosol spray comprises the following components in weight part: 10-28 parts of spermaceti, 5-14 parts of tea saponin, 5-14 parts of potassium stearate, 2-8 parts of sodium alkyl benzene sulfonate, 1-3.5 parts of sulfaguanidine, 5-15 parts of silicone oil, 5-13 parts of polyacrylamide, 0.5-2.5 parts of polydimethylsiloxane, 0.5-2 parts of lotus flower essential oil, 18-36 parts of ethyl alcohol and 80-145 parts of distilled water. The aerosol spray provided by the invention is excellent in stain removal effect, can remove various kinds of dirt on woolen clothes, kills bacteria on the clothes, and can also remove peculiar smell of clothes.

Owner:SUZHOU AILIFANG CLOTHES CO LTD

Novel method for increasing yield of epsilon-poly-L-lysine

ActiveCN101671703BHigh yieldImprove acquisitionMicroorganism based processesFermentationBiotechnologySulfanilamide

The invention relates to a novel method for increasing the yield of epsilon-poly-L-lysine, comprising the following steps: adopting Streptomyces diastatochromogenes or Streptomyces albulus which has resistance to S-(2 amino ethyl)-L- cysteine (called AEC for short), glycin and sulfaguanidine), and carrying out the fermentation production of the epsilon-poly-L-lysine through adding mixed solution of L-lysine, glucose and (NH4)2SO4 in a fed-match mode. The novel method can increase the yield by 25-50 percent than the process of with out the fed batch of L-lysine. The invention changes the method of the original production process, obviously increases the yield of the epsilon-poly-L-lysine, lowers the cost, and can be used for industrial scale fermentation.

Owner:TIANJIN UNIV OF SCI & TECH

Drug for treating piglet diarrhea and using method

InactiveCN105412144AEffective in treating diarrheaTreat diarrheaDispersion deliveryInorganic active ingredientsMedicineTherapeutic effect

The invention relates to a drug for treating piglet diarrhea and a using method. The drug for treating the piglet diarrhea is prepared from a drinking additive and a feed additive, wherein the drinking additive is prepared from, by weight, 70-90 g of fig leaves, 20-40 g of mulberry leaves, 30-50 g of hawthorn leaves, 20-40 g of loquat leaves, 20-40 g of tea leaves, 10-20 g of dried ginger, 10-15 g of brown sugar, 1-2 g of oxytetracycline, 2-4 g of baking soda and 1-2 g of sulfaguanidine, and the feed additive is prepared from, by weight, 30-50 g of white sugar, 20-40 g of garlic, 10-20 g of rhizoma coptidis and 2-5 g of mequindox. According to the drug for treating the piglet diarrhea and the using method, the drinking additive and the feed additive are cooperatively used to treat the piglet diarrhea from drinking water and feed and balance and regulate the physiological status of piglets, the treatment effect is good.

Owner:广西南宁劲能农业科技有限公司

Composition for treating chicken enterovirus syndrome and its preparation method

InactiveCN102309504AReduce bleedingGood killing effectAntibacterial agentsOrganic active ingredientsEnterovirusPotassium

The invention discloses a composition for treating a chicken enterovirus syndrome and its preparation method, and aims to provide a composition able to treat the chicken enterovirus syndrome, address both the symptoms and root causes, correct electrolyte balance and strengthen curative effects as well as a preparation method thereof. The composition comprises by weight: 15-25% of sulfaguanidine, 15-25% of, 3-7% of vitamin K, 5% of sodium chloride, 5% of potassium chloride, and the balance anhydrous glucose. The sulfaguanidine adopted in the invention is not adsorbed in chicken intestines. By contact killing of coccidians, dimetridazole can kill anacerobes causing the enterovirus syndrome. The combined use of sulfaguanidine and dimetridazole can be directed to kill coccidians and anacerobes causing the enterovirus syndrome. Potassium chloride and sodium chloride can correct electrolyte balance, and reduce adverse reactions caused by electrolyte loss due to chicken diarrhoea. Able to stop bleeding, vitamin K3 can reduce intestinal bleeding resulted from the enterovirus syndrome. Combined use of multiple drugs in the composition of the invention can effectively treat the enterovirus syndrome.

Composition for treating chicken enterovirus syndrome and its preparation method

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Owner:TIANJIN SHENGJI GRP CO LTD

L-leucine high-yield bacterium and fermentation method using the same for L-leucine production

ActiveCN1314798CHas industrial practical valueBacteriaMicroorganism based processesMicrobiologyNitrosoguanidines

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Owner:WUXI JINGHAI AMINO ACID

Medicine for preventing and treating enterogastritis in bamboo rats and preparation method of medicine

InactiveCN108635468APromote digestionEnhance digestionOrganic active ingredientsDigestive systemIntestinal structureSodium Bentonite

The invention belongs to the technical field of breeding of bamboo rats, and in particular discloses a medicine for preventing and treating enterogastritis in bamboo rats and a preparation method of the medicine. The medicine for preventing and treating enterogastritis in the bamboo rats is mainly prepared by the following materials through baking, extracting, mixing and drying: 10-15 parts of bentonite, 5-9 parts of silicon dioxide, 2-5 parts of sulfaguanidine, 1-5 parts of potassium clavulanate, 1-3 parts of a yeast, 5-10 parts of cherokee rose fruit, 3-8 parts of tea leaves, 3-8 parts of fructus crataegi, 2-8 parts of flos chrysanthemi and 1-5 parts of herba patriniae. The medicine for preventing and treating enterogastritis in bamboo rats provided by the invention, in accordance with principles of cooperative matching and assistant matching, combines chemical medicines and natural Chinese herbal medicines; the medicine mainly functions as diminishing inflammation and killing bacteria, clearing way heat and toxic materials, assisted by effects of clearing intestines and checking diarrhea; the medicine can be used for effectively preventing and treating the enterogastritis in bamboo rats and bring about benefits for healthy growth of the bamboo rats; in addition, the preparation method is simple; and various raw materials can be effectively combined.

Owner:陆川县米场镇华屋竹鼠养殖场

Application of electrochemical immunosensor in detection of multi-residue of sulfonamide medicines

InactiveCN107966484ALow costEasy to makeMaterial electrochemical variablesSulfur drugSulfadiazine

The invention discloses an application of an electrochemical immunosensor in detection of multi-residue of sulfonamide medicines. The application includes the steps of: physically modifying the surface of a glass-carbon electrode with a graphene-chitosan composite, and modifying the material with sulfadiazine through physical adsorption. On the basis of a detection method that a sulfadiazine antibody can be reacted with the sulfonamide medicine through a cross-immune reaction and indirect competitiveness is also employed, multi-residue detection on four sulfonamide medicines, including sulfadiazine, sulfaguanidine, sulfadimidine and sulfacetamide, detection limit being 0.006-0.1 ng / mL and linear range being 0.01-1000 ng / mL.

Application of electrochemical immunosensor in detection of multi-residue of sulfonamide medicines

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Owner:南京师范大学淮安研究院

High-inosine-yield strain breeding method

InactiveCN106282155AIncreased resistance to sulfaguanidineEasy to synthesizeMutant preparationHybrid cell preparationInosineUltraviolet lights

The invention discloses a high-inosine-yield strain breeding method which comprises the following steps: irradiating the initial strains under ultraviolet light, screening out an antibiotic / sulfaguanidine-resistant double-antimicrobial strain by a gradient plate process, and carrying out shake flask fermentation on the double-antimicrobial strain to obtain the strain with higher inosine yield; and fusing two or more different antibiotic-resistant strain bioplasms by genome rearrangement, screening out the multi-antibiotic-resistant strain, and carrying out shake flask fermentation to screen out the high-inosine-yield strain. The method greatly enhances the Bacillus subtilis inosine yield, and maintains favorable characteristics of the strain.

Owner:上海瑞丰农业科技有限公司 +1

Aerosol spray for dry cleaning of woolen clothes and preparation method of aerosol spray

ActiveCN103468416BEasy maintenanceGood decontamination effectOrganic detergent compounding agentsSurface-active detergent compositionsBiotechnologySpermaceti

The invention relates to a spray for dry cleaning woolen clothes and a preparation method thereof. The spray contains the following components in parts by mass: 10-28 parts of spermaceti, 5-14 parts of tea saponin, and 5-14 parts of potassium stearate , 2-8 parts of sodium alkylbenzene sulfonate, 1-3.5 parts of sulfaguanidine, 5-15 parts of silicone oil, 5-13 parts of polyacrylamide, 0.5-2.5 parts of polydimethylsiloxane, 0.5-2 parts of lotus essential oil Parts, 18-36 parts of ethanol, 80-145 parts of distilled water. The spray provided by the invention has good decontamination effect, can remove various stains on the woolen clothes, kill bacteria on the clothes, and can also remove peculiar smells on the clothes.

Owner:SUZHOU AILIFANG CLOTHES CO LTD

An ultrasensitive electrochemical immunosensor for multi-residue detection of sulfonamides

InactiveCN107703296BHigh sensitivityRealize detectionMaterial electrochemical variablesSulfur drugAntiendomysial antibodies

The invention discloses an application of an electrochemical immunosensor in the aspect of multi-residue detection of sulfonamides. According to the application, firstly, the surface of a glassy carbon electrode is modified with polysulfadiazine with an in-situ electrochemical polymerization method, secondly, detection for four sulfonamides including sulfadiazine, sulfamethazine, sulfacetamide andsulfaguanidine is realized on the basis of cross-immune response of sulfadiazine antibodies and sulfonamides, wherein the limit of detection is in a range of 0.06-0.15 ng / mL, and linear range is 0.1-1500 ng / mL or 0.3-500 ng / mL.

An ultrasensitive electrochemical immunosensor for multi-residue detection of sulfonamides

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Owner:南京师范大学淮安研究院

A strain of Streptomyces producing ε-polylysine and its application

ActiveCN110656065BImprove synthesis abilityIncrease productivityBacteriaMicroorganism based processesBiotechnologySuccinic acid

The invention discloses a strain of streptomyces producing ε-polylysine and its application, belonging to the technical field of bioengineering. The Streptomyces albulus strain (Streptomyces albulus) M-Z18 of the present invention has been deposited in the China General Microorganism Collection and Management Center on July 29, 2019, and the preservation number is CGMCC NO: M 2019589. The Streptomyces albicans M-Z18 strain of the present invention can grow rapidly on a medium with succinic acid as a carbon source, and has the ability to efficiently synthesize ε-polylysine with sulfaguanidine resistance. The strain of the present invention carries out fed-batch fermentation under the pH shock strategy, the cumulative concentration of ε-polylysine can reach 54.7g / L, and the production efficiency can reach 6.83g / L / d, which is a strain of ε-polylysine with great potential Polylysine industrial production strain.

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Owner:JIANGNAN UNIV

Wool cleaning agent

InactiveCN102399638AEasy to useNon-ionic surface-active compoundsOrganic detergent compounding agentsEster sulfonateCleansing Agents

The invention discloses a wool cleaning agent, comprising fatty alcohol polyoxyethylene ether, succinate ester sulfonate, sulfaguanidine, fatty alcohol alkanol amide, urea, and water. The invention has the advantages of reasonable formula, good effect, and low production cost.

Owner:汪明

Enhanced cleaning agent

InactiveCN108707917AImprove rust resistanceImprove decontamination abilitySodium acetateCleansing Agents

The invention discloses an enhanced cleaning agent which is prepared from the raw materials of, by weight, 4.2 to 5.6 parts of tert-butylbenzoic acid, 1.4 to 5.3 parts of tetrahydroglyoxaline, 1.6 to4.3 parts of rust-resisting materials, 2.3 to 6 parts of ethylenediamine tetraacetic acid, 0.8 to 1.7 parts of alkyl amphoteric sodium acetate, 3.5 to 9 parts of triethanolamine, 4.5 to 8 parts of sulfanilylguanidine, 3.6 to 8.4 parts of zostera marina extract, and 2.6 to 4.8 parts of tributyl phosphate. The enhanced cleaning agent provided by the invention is high in cleaning efficiency, high incleaning speed, and high in detergency.

Owner:TIANCHANG RUNDA METAL ANTIRUST AUX

Continuous hydrolysis method of sulphaguanidine alkali precipitation solution

ActiveCN113416158AAchieve recyclingEasy to handleOrganic compound preparationSulfonic acid amide preparationFluid phasePhysical chemistry

The invention discloses a continuous hydrolysis method of a sulphaguanidine alkali precipitation solution, which comprises the following steps: heating the sulphaguanidine alkali precipitation solution to 160-180 DEG C, carrying out continuous reaction and gas-liquid separation to obtain a first gas-phase product and a first liquid-phase product, and crystallizing the first liquid phase product to obtain sulfanilamide sodium; (b) carrying out selective ammonia gas absorption on the first gas-phase product, and carrying out pressure reduction and heat exchange to obtain an ammonia-containing solution; (c) rectifying the ammonia-containing solution to obtain a tower top product and a tower bottom product; (d) condensing and refluxing the tower top product to obtain a second gas-phase product and a second liquid-phase product; and (e) controlling the reflux ratio of the second liquid-phase product, enabling part of the second liquid-phase product to be refluxed for rectification, and enabling the rest part of the second liquid-phase product to form ammonia water. The sulfaguanidine alkali precipitation solution is treated by a specific process flow, so that the sulfaguanidine sodium and the ammonia water can be recycled.

Continuous hydrolysis method of sulphaguanidine alkali precipitation solution

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Owner:湖南吴赣药业有限公司

Feed additive for treating red skin disease for crucian feeding

InactiveCN109938217APromote absorptionQuick resultsFood processingClimate change adaptationMalachite greenDisease

Owner:刘伯利

Green synthesis method of sulfadiazine

PendingCN111269187AReduce productionOrganic chemistryAlcoholSulfadiazine

The invention discloses a green synthesis method of sulfadiazine. The green synthesis method comprises the following steps: (a) adding 3-alkoxy acrolein into a mixture of an organic alcohol solvent and sulfaguanidine, mixing, heating, and refluxing to perform cyclization reaction; (b) after the cyclization reaction is finished, cooling the mixed material to carry out solid-liquid separation to obtain a solid which is a sulfadiazine crude product, and recycling the obtained liquid; (c) adding the sulfadiazine crude product into liquid caustic soda, heating to carry out salifying reaction, thenstirring to decolorize, and filtering to obtain filtrate; and (d) dropwise adding a hydrochloric acid solution into the filtrate, carrying out acidification crystallization, separating crystals, and drying. Phosphorus-containing organic waste liquid is not generated, and the solid waste generation amount is low.

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Owner:湖南吴赣药业有限公司

A kind of bio-based antibacterial coating and preparation method thereof

ActiveCN109762447BGood antibacterial effectStable chemical propertiesAntifouling/underwater paintsPaints with biocidesFirming agentSulfanilamide

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Owner:SHENYANG SHUNFENG IND GRP CO LTD

Chemically modified electrode for sensitive detection of sulfaguanidine and preparation method and application thereof

ActiveCN110208342AImprove accuracyGood and enrichment ability AccuracyMaterial electrochemical variablesElectrochemical responseHeterojunction

The invention discloses a chemically modified electrode for sensitive detection of sulfaguanidine and a preparation method and application thereof. The chemically modified electrode is a high-electroactivity AgPt@MXene nanocomposite modified glassy carbon electrode, and relates to the field of electroanalytical chemistry and electrochemical sensors. The AgPt@MXene heterojunction nanocomposite hasa large specific surface area and high catalytic activity, and is capable of enhancing the enrichment amount of the sulfaguanidine in the detection mediums, improving the sensitivity of the measurement, effectively accelerating the electron transfer and improving the electrochemical response signal. The prepared chemically modified electrode is good in selectivity, simple, low in cost and good instability, is suitable for on-site detection, and is successfully applied to the accurate detection of the sulfaguanidine in animal-derived foods.

Chemically modified electrode for sensitive detection of sulfaguanidine and preparation method and application thereof

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Owner:XINYANG NORMAL UNIVERSITY

Kit for nucleic acid extraction

PendingCN113897351AAvoid degradationStable storageMicrobiological testing/measurementDNA preparationPhosphateActive agent

The invention discloses a kit for nucleic acid extraction, the kit comprises a nucleic acid extraction component, the nucleic acid extraction component comprises guanidine salt, a surfactant, a buffer component and a chelating agent; the guanidine salt is one or more of sulfaguanidine, guanidine hydrochloride, guanidine cyanate, guanidine carbonate or guanidine nitrate; the surfactant is one or more of stearic acid, sodium dodecyl benzene sulfonate, quaternization compound, lecithin, alkyl glucoside, fatty glyceride, fatty acid sorbitan or polysorbate; and the buffer component is phosphate, Tris, carbonate or acetate. According to the nucleic acid extraction kit provided by the embodiment of the invention, after the sample is extracted by the nucleic acid extraction reagent, the impurity content can be effectively reduced, background enzymes are removed to prevent product degradation, meanwhile, a target product is protected, and the extraction efficiency is remarkably improved.

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Owner:易普森生物科技(深圳)有限公司

Malachite green detection method in a kind of aquatic products

ActiveCN109507126BImprove specific recognition abilityHigh detection sensitivityColor/spectral properties measurementsMalachite greenMalachite green stain

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Owner:JIMEI UNIV

A cleaning agent for removing residual pesticides on fruit and vegetable

InactiveCN104651068AAvoid harmNo side effectsNon-ionic surface-active compoundsDetergent compounding agentsBiotechnologyAcetic anhydride

A cleaning agent for removing residual pesticides on fruit and vegetable is disclosed. The cleaning agent is prepared from following raw materials by weight: 0.5-3 parts of amino acids, 15-25 parts of acetic anhydride, 5-10 parts of sodium alkylsulfate, 3-6 parts of natural plant oleyl alcohol polyoxypropylene, 1-3 parts of acrylic acid-maleic anhydride copolymer, 15-20 parts of sulfaguanidine and 15-20 parts of deionized water. The beneficial effects of the cleaning agent are that: the cleaning agent is advantaged by being harmless to skin, mild, little in irritation, low in toxicity, strong in degreasing capability, biodegradable, environmental friendly, and the like; the pH value is neutral, so that the cleaning agent is free of harm to hands really; the cleaning agent does not aggregated in a human body even if the cleaning agent is not cleanly washed, and can be excreted from the human body; and the cleaning agent is free of phosphate and free of toxic and side effects.

Owner:QINGDAO JINLIANXIN BUSINESS & TRADE

Medicine premix for treating and preventing donkey primary enteritis and digestive diarrhea and preparation method thereof

InactiveCN110326712AHigh nutritional valueImprove immunityHydrocarbon active ingredientsAntipyreticDiseaseImmunocompetence

The invention discloses a medicine premix for treating and preventing donkey primary enteritis and digestive diarrhea and a preparation method thereof. The medicine premix is mainly composed of the following components in parts by weight: 550-800 parts of sweet potato leaves, 360-500 parts of bean cakes, 130-300 parts of mung bean hulls, 130-200 parts of sugarcane dry straw powder, 5-10 parts of afeed additive, 0.2-0.5 part of sulfaguanidine, 0.1-0.2 part of aspartame, 0.03-0.04 part of white camphor oil, 1-1.3 parts of table salt, 0.03-0.04 part of slow-release potassium, 20-30 parts of diatomite, 15-40 parts of a filler and 0.1-0.2 part of lubricating powder. The medicine premix can effectively prevent and treat enteritis diseases, digestive diarrhea and other problems, has a certain health-care function on donkeys, and can improve the immunocompetence of donkeys.

Owner:SHANDONG VOCATIONAL ANIMAL SCI & VETERINARY COLLEGE

32 results about "Sulfaguanidine" patented technology

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