2 results about "Sulfa drug" patented technology

The present invention discloses a compound solution of a sulfonamide and an antimicrobial synergist, its preparation method, and application. The compound solution further comprises a solvent, a pH buffer system, and a diluent; the solvent is N-methylpyrrolidone, and the pH buffer system is triethanolamine and an organic acid. The present invention discloses a stable, clear compound solution of a sulfonamide and an antimicrobial synergist, and its preparation method. The compound solution can be mixed with water for administration, exhibits excellent stability and lacks a distinctive odor after mixing with water, and eliminates problems such as uneven mixing of existing premixes and low intake of sick animals when their appetite decreases.

This invention discloses a mixed broad-spectrum nucleic acid aptamer for the simultaneous detection of nine sulfonamide drugs and its applications. The mixed broad-spectrum nucleic acid aptamer is composed of nucleic acid aptamer sequences Sul-01 and Sul-04, which can be used as probes to construct a ratiometric fluorescence method for the simultaneous detection of nine sulfonamide drugs. The mixed broad-spectrum nucleic acid aptamer provided by this invention exhibits high specificity and high binding affinity for multiple sulfonamide drugs. The detection method established using it can achieve rapid, low-cost, and highly sensitive simultaneous detection of nine sulfonamide drug residues in aquatic environments and seafood.