Disinfection sterilizing type medical supersonic couplant and method of preparing the same
An ultrasonic couplant, disinfection and sterilization technology, applied in pharmaceutical formulations, preparations for in vivo experiments, etc., can solve the problems of sound wave conduction and image clarity, cumbersome operation, and lack of sterility, and achieve fast and long-term effects. The effect of bactericidal function
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Embodiment 1
[0014] Prepare according to the following components and weight percentages
[0015] 0.05-0.15% of polyhexamethylene biguanide, 0.1-0.2% of hydroxyethyl cellulose, 1-10% of propylene glycol, and the balance is deionized water.
[0016] Preparation method: disperse hydroxyethyl cellulose in propylene glycol, add enough deionized water to stir and disperse, heat to 75-80 ° C, keep the temperature for 30 minutes, when the liquid is transparent, cool to 45 ° C, add polyhexamethylene biguanide, stir and cool , and finally canned.
[0017] Take the preparation of 1000kg of this medical ultrasonic couplant as an example, and weigh it according to the following weight
[0018] The concentration is 5kg of 20% polyhexamethylene biguanide, 20kg of hydroxyethyl cellulose, 100kg of propylene glycol, and 875kg of deionized water.
[0019] Preparation method: Disperse 20kg of hydroxyethyl cellulose in 100kg of propylene glycol, add 875kg of deionized water, heat to 80°C for dissolving for ...
Embodiment 2
[0021] Prepare according to the following components and weight percentages
[0022] 0.01-0.1% of polyhexamethylene biguanide, 0.01-0.1% of chlorhexidine acetate, 0.1-0.2% of hydroxyethyl cellulose, 1-10% of propylene glycol, and the balance being deionized water.
[0023] Preparation method: under the requirement that polyhexamethylene biguanide + chlorhexidine acetate is 0.05 to 0.15%, respectively weigh polyhexamethylene biguanide and chlorhexidine acetate within the above ranges of polyhexamethylene biguanide and chlorhexidine acetate. Chlorhexidine acetate, then disperse hydroxyethyl cellulose in propylene glycol, add enough deionized water to stir and disperse, heat to 75-80 ℃, keep the temperature for 30 minutes, when the liquid is transparent, cool to 45 ℃, add polyhexamethylene The base biguanide and chlorhexidine acetate are stirred and cooled, and finally canned.
Embodiment 3
[0025] Prepare according to the following components and weight percentages
[0026] 0.01-0.1% of benzalkonium chloride, 0.01-0.1% of chlorhexidine acetate, 0.1-0.2% of hydroxyethyl cellulose, 1-10% of propylene glycol, and the balance being deionized water.
[0027] Preparation method: disperse hydroxyethyl cellulose in propylene glycol, add enough deionized water to stir and disperse, heat to 75~80℃, keep warm for 30min, when the liquid is transparent, cool to 45℃, add benzalkonium chloride and acetic acid chloride It has to be stirred and cooled, and finally canned.
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