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Sterilizing agent, preparation method and use thereof

A technology of disinfectant and emulsifier, which is applied in the field of bactericidal disinfectant and bactericidal disinfectant manufacturing, which can solve the problems of skin irritation, limitation of the use of disinfectant, mucous membrane or skin irritation, etc., and achieve strong sterilizing power, long sterilizing duration and effective fast effect

Active Publication Date: 2006-02-08
吴吉平 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Chlorhexidine acetate has long been recognized internationally as an intermediate-effect disinfectant, but chlorhexidine acetate is white or almost white crystalline powder, which is insoluble or slightly soluble in water, and only soluble in alcohol or alcoholic solutions similar to alcohol. Therefore, the disinfectant containing chlorhexidine acetate generally contains alcohol or alcohol-like alcohol solution. As we all know, if the disinfectant containing alcohol or alcohol-like disinfectant is directly sprayed on the mucous membrane or skin of the human body, especially the suppurative or festering The surface of the skin will irritate the mucous membrane or skin, which limits the use of disinfectant to varying degrees
[0003] Chinese invention patent ZL97108543.9 discloses "an antibacterial bactericide and its production process". The antibacterial bactericide is composed of chlorhexidine acetate, ethanol, glycerol and OP emulsifier. and glycerin, so it has strong irritation to the skin
[0004] Chinese invention patent ZL02126050.8 discloses "preoperative skin disinfectant", which is formulated from chlorhexidine acetate, benzalkonium bromide, glycerol, nonylphenol polyoxyethylene ether and distilled water, although its bactericidal Works well, but it contains glycerol, so it's a strong skin irritant

Method used

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Examples

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Effect test

Embodiment 1

[0025] Bactericidal disinfectant of the present invention, it comprises: pure water and mother liquor, and mother liquor is compound water-soluble mother liquor, and it comprises: chlorhexidine acetate (chlorhexidine acetate), benzalkonium bromide, sulfonium acetyl ammonium, polyethylene glycol Alcohol octyl phenyl ether and purified water, the proportions by weight of each component in the mother liquor are as follows: 8 for chlorhexidine acetate, 2 for benzalkonium bromide, 0.5 for sulfonium acetate ammonium, 0.5 for polyethylene glycol octyl Base phenyl ether is 4 and water is 10.5, and mother liquor is diluted with water to make the content of chlorhexidine acetate account for 0.15% of the bactericidal disinfectant gross weight in the bactericidal disinfectant.

[0026] Its preparation method is as follows:

[0027] Add the chlorhexidine acetate and polyethylene glycol octylphenyl ether into pure water with the same weight as the chlorhexidine acetate, stir evenly, heat to...

Embodiment 2

[0029] Bactericidal disinfectant of the present invention, it comprises: distilled water and mother liquor, and mother liquor comprises: chlorhexidine acetate, benzalkonium bromide, sulfonium acetyl ammonium, macrogol octylphenyl ether and distilled water, each component in mother liquor The parts by weight are as follows: chlorhexidine acetate is 10, benzalkonium bromide is 3, sulfonium acetate ammonium is 1, polyethylene glycol octylphenyl ether is 5 and water is 14, and the mother liquor is diluted with water to use The content of chlorhexidine acetate in the bactericidal disinfectant accounts for 0.2% of the total weight of the bactericidal disinfectant.

[0030] Its preparation method is as follows:

[0031] Add the chlorhexidine acetate and polyethylene glycol octylphenyl ether into distilled water with the same weight as the chlorhexidine acetate, stir evenly, heat to 85°C to dissolve and cool to normal temperature, then add benzalkonium bromide The aqueous solution of...

Embodiment 3

[0033] Bactericidal disinfectant of the present invention, it comprises: distilled water and mother liquor, and mother liquor comprises: chlorhexidine acetate, benzalkonium bromide, sulfonium acetyl ammonium, macrogol octylphenyl ether and distilled water, each component in mother liquor The parts by weight are as follows: chlorhexidine acetate is 12, benzalkonium bromide is 4, sulfonium acetate ammonium is 1.5, polyethylene glycol octylphenyl ether is 6 and water is 17.5, and the mother liquor is diluted with water to make The content of chlorhexidine acetate in the bactericidal disinfectant accounts for 0.25% of the total weight of the bactericidal disinfectant.

[0034] Its preparation method is as follows:

[0035]Add the chlorhexidine acetate and polyethylene glycol octylphenyl ether into pure water or distilled water equal in weight to the chlorhexidine acetate, stir evenly, heat to 90°C to dissolve, cool to normal temperature, and then add The aqueous solution of benza...

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PUM

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Abstract

The invention relates to a sterilizing and disinfecting agent, its preparing process and use thereof, wherein the sterilizing and disinfecting agent comprises water and compound water-soluble mother liquor, the mother liquor comprises (by weight parts) acetic chlorhexidine 8-12, benzalkonium bromide 2-4, sulfonyl acetic ammonium 0.5-1.5, OP emulsifying agent 4-6 and water 10.5-17.5, the mother liquor is diluted with water till the content of the acetic chlorhexidine is 0.15-0.25%.

Description

technical field [0001] The invention relates to a bactericidal disinfectant, a method for manufacturing the bactericidal disinfectant and its application, in particular to a bactericidal disinfectant which is non-toxic and non-irritating to the human body, a method for manufacturing the bactericidal disinfectant and its application. Background technique [0002] Chlorhexidine acetate has long been recognized internationally as an intermediate-effect disinfectant, but chlorhexidine acetate is white or almost white crystalline powder, which is insoluble or slightly soluble in water, and only soluble in alcohol or alcoholic solutions similar to alcohol. Therefore, the disinfectant containing chlorhexidine acetate generally contains alcohol or alcohol-like alcohol solution. As we all know, if the disinfectant containing alcohol or alcohol-like disinfectant is directly sprayed on the mucous membrane or skin of the human body, especially the suppurative or festering The surface of...

Claims

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Application Information

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IPC IPC(8): A01N47/44A61K8/40A61Q17/02
Inventor 丁荣盛刘震吴吉平
Owner 吴吉平
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