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Method for simultaneously measuring contents of multiple skin disinfectants in wet tissue

A technology of disinfectant and wet wipes, applied in the field of chemical detection, can solve problems such as skin damage and inability to disinfect other items, and achieve the effect of quality control and rapid and effective analysis

Inactive Publication Date: 2016-09-21
WUZHOU INST FOR FOOD & DRUG CONTROL
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The wet wipes on the market can be roughly divided into two categories: one is to be sterilized itself, but cannot sterilize other items, and contains skin care ingredients, which can only be used for skin moisturizing and maintenance
The other type is disinfectant wipes that are not only disinfected themselves, but can also disinfect other items. They can be used to disinfect or sterilize skin abrasions and scratches. Generally, disinfection or sterilization will be indicated on the packaging ingredients, but the usual disinfectants have some damage to the skin, if used in excess, it will cause serious damage to the skin

Method used

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  • Method for simultaneously measuring contents of multiple skin disinfectants in wet tissue

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Embodiment 1

[0020] A method for simultaneously detecting the content of multiple skin disinfectants in wet wipes is to simultaneously determine chlorhexidine gluconate, chlorhexidine acetate, 2,4,4"-trichloro-2 in wet wipes by high performance liquid chromatography Content of "-hydroxydiphenyl ether, benzalkonium bromide, benzalkonium chloride and glutaraldehyde.

[0021] Described method is specifically as follows: has included following steps successively:

[0022] 1) Squeeze out the liquid components in the wet wipes and collect the liquid;

[0023] 2) Measure 1ml of the liquid obtained in step 1), transfer it to a 50ml volumetric flask, add 30% ethanol, ultrasonically extract for 5min, extract twice, combine the extracts and evaporate to dryness, add methanol to 50ml, filter through a 0.45um filter membrane , inject Agilant12000 high-performance liquid chromatograph detection, measure chromatogram;

[0024] 3) Weigh chlorhexidine gluconate, chlorhexidine acetate, 2,4,4"-trichloro-2"...

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Abstract

The invention provides a method for simultaneously measuring the contents of multiple skin disinfectants in the wet tissue, and aims at providing the method which has simple operating method for simultaneously measuring the contents of multiple skin disinfectants in the wet tissue. The method uses a high performance liquid chromatography method to simultaneously measure the contents of chlorhexidine gluconate, chlorhexidine acetate, 2,4,4'-trichlorine-2'-phenoxyphenol, benzalkonium bromide, benzalkonium chloride and glutaraldehyde in the wet tissue. The invention belongs to the technical field of chemical detection.

Description

technical field [0001] The invention provides a method for measuring disinfectants, specifically, a method for simultaneously detecting the contents of multiple skin disinfectants in wet wipes; it belongs to the technical field of chemical detection. Background technique [0002] As a new sanitary product in recent years, wet wipes have a wide range of uses and can be used in various occasions for personal consumption and commercial use, such as civil aviation, family, hotel, restaurant, travel, etc., and are gradually favored by people due to their convenience. With the development of people's hygiene habits and the improvement of the quality of life, wet wipes will gradually become a necessity in people's daily life. Wet wipes are a kind of paper towels made of pure water, spunlace non-woven fabric and propylene glycol for wiping face, hands, or skin. [0003] Wet wipes on the market can be roughly divided into two categories: one is sterilized itself, but cannot steriliz...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/06G01N30/12
CPCG01N30/02G01N30/06G01N30/12G01N2030/027G01N2030/126
Inventor 陈学松张云平陈启钊赖秀梅
Owner WUZHOU INST FOR FOOD & DRUG CONTROL
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