21 results about "Chlorhexidine gluconate" patented technology

The present invention relates to an antimicrobial and healing formulation for skin, designed to effectively target and treat skin conditions such as acne caused by Cutibacterium acnes, cold sore lesions due to the herpes simplex virus, and superficial wounds. This unique formulation combines antimicrobial agents, plant extracts and essential oils in specific proportions in order to exert a synergistic action, enhancing their individual efficacy in the treatment of skin conditions and promoting skin healing. The innovative formulation composed of niaouli (Melaleuca viridiflora) essential oil and tea tree (Melaleuca alternifolia) essential oil, chlorhexidine digluconate, Hamamelis virginiana extract, panthenol, glycerol, and propylene glycol. Each ingredient has been selected for its proven pharmacological properties and its synergistic potential. The formulation works in concert to reduce microbial load, alleviate inflammation, and accelerate skin healing, while providing a gentle and effective application.

The ophthalmic composition according to the present invention contains: (A) 0.01-0.5 w / w% of a copolymer having structural units represented by formulae (1a)-(1c), the molar ratio of the structural units being a: b: c = 100: 10-400: 2-50, and the weight-average molecular weight being 5,000-2,000,000; (B) from 0.001 w / w% to 0.02 w / w% (inclusive) of benzalkonium chloride; and / or (C) from 0.001 w / w% to 0.05 w / w% (inclusive) of chlorhexidine gluconate. According to the present invention, it is possible to provide an ophthalmic composition that protects corneal cells while exhibiting sufficient storage efficacy.

The invention discloses mouthwash for treating oral ulcer caused by chemoradiotherapy, which is mainly prepared from the following raw materials in percentage by weight: 0.15 percent to 0.25 percent of chlorhexidine gluconate, 0.015 percent to 0.025 percent of polypeptide of which the amino acid sequence is RWRWRW, 0.05 percent to 0.15 percent of sodium hyaluronate, 0.05 percent to 0.15 percent of menthol, 2.8 percent to 3.2 percent of humectant, 0.45 percent to 0.55 percent of sodium ascorbyl phosphate, 0.5 percent to 1 percent of sodium bicarbonate and the balance of distilled water. The mouthwash for treating the oral ulcer caused by the chemoradiotherapy not only has antibacterial and moisturizing functions, but also can relieve the pain degree of the oral ulcer caused by the chemoradiotherapy, reduce the infection risk and promote ulcer healing, the technical problem that an existing product is single in function is solved, a patient does not need to alternately use multiple preparations, and the compliance is high.

1. The name of the design product: packaging bag (chlorhexidine gluconate surface disinfection wet wipe). 2. The use of the design product: packaging bag for packaging disinfection wet wipes. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view.

The present application relates to the technical field of pharmaceutical formulations, and particularly relates to a compound miconazole nitrate lotion and a preparation process thereof, which comprises the following raw materials in percentage by weight: miconazole nitrate 1.5-2.5%, amphiphilic polymer 5-6%, chlorhexidine gluconate 1.5-2.5%, casone 0.05-0.1%, benzoic acid 0.1-0.2%, surfactant 25-32%, PEG-120 methyl glucose dioleate 1-2%, citric acid monohydrate 0.3-0.4%, and sodium chloride 0.7-0.9%, and the rest is water. The compound miconazole nitrate lotion prepared by the present application has dual effects of anti-fungus and antibiosis, expands the scope of indications, enhances the overall antibacterial effect of the lotion, and is suitable for the treatment and prevention of various skin infections.

The invention provides a composition for relieving skin injury reaction. The composition comprises tranexamic acid, melatonin and chlorhexidine gluconate. In addition, the invention provides application of the composition to preparation of medicines or cosmetics for relieving skin injury reaction, so as to achieve the effects of relieving inflammatory reaction, pain, redness and swelling, relieving bleeding and blood stasis and reducing bacterial infection opportunities.

The group of inventions relates to the field of medicine, and more particularly to haemostatics and drugs for providing temporary haemostasis in the case of non-major bleeds. Proposed are a pharmaceutical composition containing tranexamic acid, chlorhexidine digluconate, bupivacaine, and water, in the following proportions: 13-16 wt.% tranexamic acid, 2.00 wt.% chlorhexidine digluconate, 0.5 wt.% bupivacaine, and 81.5-84.5 wt.% water, and a drug in aerosol or spray form comprising said pharmaceutical composition. Use of the group of inventions makes it possible to stop bleeds very quickly and reduce the risk of renewed bleeding. In addition, providing the drug in the form of an aerosol or spray allows easy and convenient use. The proposed composition and drug can be used for providing temporary haemostasis in the case of non-major bleeds in the fields of dentistry, veterinary medicine, military field medicine, disaster medicine, and the like.

The invention discloses a gynecological cleaning solution and a preparation method thereof, and the cleaning solution comprises the following components in percentage by weight: 0.85%-1.05% of modern medical composite components, 6.0%-7.0% of traditional medical multi-stage extracts, 11.0%-13.0% of a functional auxiliary material system and the balance of purified water. The modern medical composite components comprise 11 components such as chlorhexidine gluconate, the traditional medical multi-stage extracts comprise 6 extracts such as sophora flavescens total alkaloids, and the functional auxiliary materials comprise a humectant, an emulsifier and the like. The preparation method comprises the steps of multi-stage pretreatment of medicinal materials, gradient extraction, refining and purification, nano embedding of modern components and preparation forming. The cleaning solution can efficiently inhibit and kill bacteria, fungi, trichomonad and the like in a broad spectrum, repair vaginal mucosa and maintain micro-ecological balance, has synergistic interaction of traditional Chinese medicine and western medicine and few adverse reactions, is suitable for various gynecological infectious diseases, and has good clinical application value.

The application relates to the field of ophthalmic drugs, and particularly discloses an eye drop, which comprises the following components in mass fraction: 0.003%-0.2% of chlorhexidine gluconate; and 0.025%-0.05% of chloramphenicol. Since acanthamoeba usually feeds on bacteria, the chlorhexidine gluconate is used as a main component to kill acanthamoeba in the application, and the antibiotic chloramphenicol is added, so that the keratitis caused by bacterial infection can be avoided, the ocular surface bacteria can be killed, the nutrition source of acanthamoeba can be reduced, and the treatment of acanthamoeba keratitis can be synergistically strengthened.

This invention relates to the field of shampoo technology, and discloses an antibacterial and anti-mite shampoo and its preparation method. The antibacterial and anti-mite shampoo is prepared from piroctone ethanolamine salt, glycerin, a mixed phase, behenamidopropyl dimethylamine, citric acid aqueous solution, chlorhexidine gluconate aqueous solution, bis-PEG-15 methyl ether polydimethylsiloxane, lemon fragrance, phenoxyethanol preservative, deionized water, and sodium chloride. The mixed phase is prepared from sodium lauryl ether sulfate, cocamidopropyl betaine, glycerin, and an aqueous phase. The aqueous phase is prepared from deionized water, disodium ethylenediaminetetraacetate, and polyquaternium-10. This invention has good antibacterial and anti-mite effects.

This invention relates to a no-rinse antibacterial cat spray composition formulated to clean, moisturize, and soothe feline fur while being safe for ingestion during grooming. The composition features chlorhexidine gluconate as an antibacterial agent, a plant-based surfactant for gentle cleansing, and moisturizing agents like glycerin and aloe vera. The formulation ensures compatibility with feline skin and fur, avoids harmful additives, and is designed for ease of use without the need for rinsing.

The invention belongs to the technical field of veterinary detergents, and discloses a safe and efficient multi-effect pet shower gel capable of killing mites, expelling parasites and sterilizing, which comprises the following components in parts by weight: 10-15 parts of a washing component, 0.1-0.5 part of an antibacterial component, 0.2-1 part of a mite-killing component, 0.2-0.8 part of a parasites-expelling component, 0.5-1 part of a moisturizing component, 0.1-0.5 part of a thickening agent and 81-88 parts of distilled water. The washing component is composed of an anionic surfactant, an ampholytic surfactant and a nonionic surfactant. The chlorhexidine gluconate used in the invention has quite wide antimicrobial activity, is green and safe, can effectively kill various germs on pet fur when being applied to clean and sanitary care of pets, has the effects of removing dandruff and relieving itching, can also kill parasite eggs and inhibit breeding of insects such as mosquitoes and flies, and has no irritation to skin and hair. The preparation technology is simple in process and high in production efficiency, has excellent antibacterial, acarus killing, insect repelling and moisturizing effects, and has good application value.

An antiseptic solution including, a cationic antiseptic agent, a film forming polymer, an anionic tinting agent, and a solvent, wherein the cationic antiseptic agent, the film forming polymer and the anionic tinting agent each remain solubilized within the solution for greater than about 1 hour at 25° C. and 60% relative humidity. The antiseptic agent is preferably octenidine dihydrochloride or chlorhexadine gluconate. The film forming polymer is preferably an acrylate polymer. The solvent is preferably ethanol, isopropanol, and n-propanol. When a drape is adhered to a dried surgical film via the antiseptic solution, the force required to peel the drape from the surgical film is at least about 105 g / 25 mm.

The invention discloses a chlorhexidine gluconate gargle and a production process thereof. The toothpaste is prepared from the following components in parts by weight: 0.5 to 2 parts of chlorhexidine gluconate, 0.1 to 0.5 part of epicatechin gallate, 1 to 3 parts of honeysuckle flower extract, 0.8 to 2.5 parts of herba taraxaci extract, 0.2 to 0.8 part of dipotassium glycyrrhizinate, 5 to 12 parts of glycerol, 3 to 8 parts of polyethylene glycol 400, 0.3 to 1 part of sodium citrate, 0.2 to 0.7 part of sodium dihydrogen phosphate, 0.1 to 0.4 part of xanthan gum, 0.05 to 0.2 part of disodium EDTA (Ethylene Diamine Tetraacetic Acid), 0.1 to 0.5 part of menthol and 0.05 to 0.3 part of stevioside. The total weight is 100 parts; according to the invention, chlorhexidine gluconate is used as a main antibacterial component, epicatechin gallate and honeysuckle and dandelion extracts are compounded, a multi-target antibacterial system is constructed, the antibacterial spectrum is widened, the antibacterial effect is enhanced, and the problem of limitation of single-component bacteriostasis is solved; the dipotassium glycyrrhizinate is added to effectively relieve the irritation of chlorhexidine gluconate, and glycerol and polyethylene glycol 400 cooperate to improve the taste and improve the use comfort of the product.

The utility model discloses a transfusion port puncture patch with catheter joint fixing device, including base body, the one side of base body is provided with first dressing layer, the upside of base body is provided with joint fixing subassembly, the bottom of first dressing layer is provided with transparent antibacterial layer and first pasting layer, transparent antibacterial layer adopts the manufacture of chlorhexidine gluconate, the upside of first dressing layer is provided with the scale mark corresponding with various specifications of transfusion port, second dressing layer, it sets up one side of first dressing layer, the joint fixing subassembly includes the fixed base that pastes the upside of base body, the one end of fixed base is provided with the bandage buckle strip of rotation, the other end of fixed base is provided with elastic buckle, the utility model can solve the problem that the current puncture patch usually only has simple fixed and protection function, can not effectively fixed catheter joint, is easy to lead to butterfly wing needle to fall off, shift, increases the infection risk, influences the patient comfort degree.

The present invention relates to a method of washing textile articles that can be carried out, for example, in a continuous batch tunnel washer. Embodiments of the present method can include treating the textile with an aqueous composition including cleaning agent and halogen-containing bleaching agent for a time sufficient to remove soil from the textile and contacting the halogen-treated textile with an aqueous composition including a peroxycarboxylic acid. The concentration of halogen after the sufficient time can be at a level that does not result in adverse interaction between the halogen-containing bleaching agent and the peroxycarboxylic acid.Embodiments of the present method can clean textiles with the results of more effective stain removal and less waste through destruction of the textile article. Further, the present invention can clean a textile contacted soiled by a composition including chlorhexidine gluconate without resulting staining of the textile, which staining could have been permanent.

The invention relates to a compound antibacterial spray for pets as well as a preparation method and application of the compound antibacterial spray. Comprising the following preparation raw materials in percentage by mass: 3-7% of chlorhexidine gluconate, 3-8% of miconazole nitrate, 3-8% of ivermectin, 5-10% of glycerol, 2-8% of a carboxymethyl cellulose solution, 12-18% of modified mesoporous silicon, 5-10% of jojoba oil, 0.1-2% of Tween 80, 1-3% of oil-soluble azone, 8-15% of absolute ethyl alcohol and 35-45% of purified water. Wherein the modified mesoporous silicon is obtained after modification of D-cysteine and / or polyethyleneimine. The preparation method comprises the following steps: loading chlorhexidine gluconate, miconazole nitrate, ivermectin, jojoba oil, Tween 80 and oil-soluble azone on modified mesoporous silicon prepared by modifying D-cysteine and / or polyethyleneimine in a multi-layer form, coating with carboxymethyl cellulose, and mixing with absolute ethyl alcohol and purified water to obtain the compound antibacterial spray for pets. The compound antibacterial spray for pets can realize a lasting antibacterial function and is relatively good in storage stability.

An integrated wound dressing device for treatment of an insertion site of percutaneous and drug delivery devices has a transparent film layer with a bottom side, a top side and a perimeter. The bottom side is coated with an adhesive impregnated with an antimicrobial agent. The transparent film has a radius cutout between a central opening and the perimeter. A liquid crystal temperature sensitive film with an adhesive placed on the top side of the transparent film layer is preferably near and around the central opening. The dressing also has a layer of double folded release paper below the bottom side of the transparent film layer. The preferred TLCs used are cholesteryl esters with a preferable temperature detection range of 35-40° C. The preferred antimicrobial agent is chlorohexidine gluconate (CHG).

The invention discloses an antibacterial plastic and a preparation method thereof, belongs to the technical field of high polymer materials, and provides introduction of functional master batch into polypropylene aiming at the problems of short aging, potential safety hazards and difficulty in inhibition of a biological membrane caused by migration of an antibacterial agent. The master batch is prepared from a carrier PP, a sulfhydrylated mesoporous silica loaded chlorhexidine gluconate slow-release unit and sulfurized chitosan with biological adhesion, and is matched with PP-g-MAH, an antioxidant and a lubricating agent through twin-screw melt blending. The preparation method comprises the following steps: firstly preparing functional master batches, and then compounding the functional master batches with matrix resin and extruding to form granules; the process temperature is 180-210 DEG C; the test shows that the initial antibacterial rate gt; the biofilm amount is obviously reduced, and the biofilm is suitable for medical instruments and food packaging. The problems of heat resistance and compatibility are solved, the release of the antibacterial agent is controlled, the migration risk is reduced, and the mechanical property is basically maintained.

The application relates to the technical field of biological medicine, and particularly discloses a medical bacteriostatic nursing gel and a preparation method thereof. The medical bacteriostatic nursing gel comprises the following raw materials in parts by weight: chlorhexidine gluconate 1-5 parts, Chinese herbal medicine 4-20 parts, ethanol 50-70 parts, glycerol 2-8 parts, hydrogenated polyisobutylene 0.01-0.1 part, carbomer 0.15-0.5 part and triethanolamine 0.2-0.7 part. The preparation method of the medical bacteriostatic nursing gel comprises the following steps: S1, the Chinese herbal medicine is extracted by using ethanol, the filtrate is mixed with glycerol after filtration, and the components except carbomer and triethanolamine are added and uniformly mixed, ultrasonic dispersion is carried out to obtain a mixed solution I; S2, the carbomer is added into the mixed solution I and stirred, and the gel is obtained after overnight standing; and S3, the triethanolamine is added into the gel and stirred, and the pH is adjusted to obtain the medical bacteriostatic nursing gel. The medical bacteriostatic nursing gel prepared by the application is mild and non-irritating, and has good bacteriostatic effect.

The present invention provides a dimethicaine compound formulation and a preparation method thereof. The dimethicaine compound formulation comprises the following raw materials in parts by weight per 100 parts of the compound formulation: 2-5 parts of dimethicaine and 2-5 parts of trimecaine. The dimethicaine compound formulation contains chlorhexidine gluconate, Tween 80, oleic acid, polyethylene glycol 400, and purified water. The compound formulation comprises the following raw materials in parts by weight per 100 parts of the compound formulation: 2-5 parts of dimethicaine, 2-5 parts of trimecaine, 0.1-0.3 parts of chlorhexidine gluconate, 4-6 parts of Tween 80, 4-6 parts of oleic acid, 15-25 parts of polyethylene glycol 400, and the balance purified water. The present invention utilizes dimethicaine and trimecaine for compounding, which can effectively enhance the blocking effect, synergistically improve the anesthetic effect, reduce the dosage of anesthetic drugs, reduce side effects, and improve safety. Secondly, the present invention adds polyvinyl pyrrolidone K90, polyglycerol ester and ascorbic acid in a specific ratio to further improve the bioavailability of anesthetic drugs, enhance the anesthetic effect, and further improve the stability of anesthetic drugs.