204 results about "Chlorhexidine gluconate" patented technology

Toothpaste incorporating chlorhexidine bigluconate for improved adhesive onto the surface of the teeth. A second embodiment discusses the use of triclosan and in combination with sodium monofluorphosphate for use in the toothpaste.

Pharmaceutical dental gel preparation comprising of metronidazole benzoate, chlorhexidine gluconate, and local anesthetic as the active ingredient; glycol as the solvent medium; a carboxyvinyl polymer, cross-linked polymer of acrylic acid copolymerized with polyalkylsucrose as a gelling agent.

The invention relates to a silicone catheter including chlorhexidine gluconate, methods of making this catheter, and methods of using it. The method of making the catheter includes contacting a silicone catheter with a liquid containing chlorhexidine gluconate. Chlorhexidine gluconate is stably incorporated into the silicone catheter.

The invention also relates to a silicone medical device or article including chlorhexidine gluconate and methods of making this such a medical device or article.

Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C₂-C₅ alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a fatty component containing at least one free hydroxyl group, such as a C₁₂-C₂₁ fatty alcohol, a C₁₂-C₂₁ fatty ester, a C₁₂-C₂₁ fatty ether, a C₁₂-C₂₁ fatty amide, and combinations thereof; and optionally an emollient ester such as diesters of bibasic acids and triesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C₂-C₅ alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a hydrophobic polymer soluble in the lower alcohol; an emollient ester such as diesters of bibasic acids and triesters of citric acid; and an optional fatty component containing at least one free hydroxyl group, such as a C₁₂-C₂₁ fatty alcohol, a C₁₂-C₂₁ fatty ester, a C₁₂-C₂₁ fatty ether, a C₁₂-C₂₁ fatty amide, and combinations thereof. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

A disinfectant delivery system and method of providing alcohol-free disinfection to a body to be disinfected, as well as a method of infection reduction by preparation of a patient before an invasive procedure. A blended cloth comprising first fibers and second fibers is provided with the first fibers generally being greater in quantity by weight than the second fibers. A disinfectant solution impregnates the blended cloth, with the disinfectant solution having chlorhexidine gluconate as an active ingredient and having no alcohol. In the method according to the invention, at least one impregnated blended cloth is used to disinfect at least a portion of a body. A plurality of blended cloths can be provided for disinfecting discrete portions of the body. When an invasive procedure is to be performed on a patient, a further method according to the invention of infection reduction comprises using a CHG-impregnated cloth to disinfect at least a portion of the patient at least one day prior to the invasive procedure proximate the location of the invasive procedure.

The present invention provides a germicidal antiseptic composition for dilution, which is superior in preparation stability, and free of formation of insoluble precipitation even when diluted with water containing an inorganic ion (e.g., tap water etc) when in use, thereby retaining superior germicidal disinfection ability. The present invention relates to a germicidal antiseptic composition for dilution, which is an aqueous liquid comprising chlorhexidine gluconate as a main ingredient, (1) 1-10 w/v % of chlorhexidine gluconate; (2) 1-10 w/v % of one or more selected from the group consisting of a polyoxyethylene alkyl ether and a polyoxyethylene alkenyl ether, each having an HLB of 10-15 and a congeal point of not more than 35° C.; (3) 0.001-0.5 w/v % of a water-soluble organic monocarboxylic acid having 2 to 6 carbon atoms; and (4) water.

Devices, coating compositions and methods for making such compositions are provided, wherein the coatings deliver chlorhexidine gluconate from a stable non-aqueous system.

The invention discloses a formula for non-clean disinfectant with skin protection effects and a method for preparing the non-clean disinfectant. The non-clean disinfectant in the formula comprises, by weight, 0.1%-1.0% of thickening agents, 0.1%-10.0% of disinfectants, 20.0%-40.0% of solubilizing assistants, 10.0%-20.0% of inclusion agents, 0.2%-2.0% of neutralizers, 1.0%-10.0% of humectants, 1.0%-10.0% of skin protectants, 0.2%-2.0% of essence and the balance deionized water. The formula and the method have the advantages that the problem that anions and cations cannot coexist is solved, and carbomer which is an anionic thickening agent and chlorhexidine gluconate which is a cationic disinfectant can coexist in the same system; moisturizing and skin protection effects of the non-clean disinfectant are additionally realized, and accordingly the skins of the hands of users can be nourished, not only can be disinfected, but also can be protected and can be protected on the basis of disinfection; the sterilization capacity can be reinforced, antibacterial effects can be continuously realized, and accordingly infection can be prevented; pungent smell of disinfection components can be reduced, and accordingly the non-clean disinfectant smells fresh and can be easily accepted by the public; the non-clean disinfectant is portable and is convenient to use and suitable for the public, and the skins of the hands of the users can be disinfected by the aid of the non-clean disinfectant at any time in any places.

The invention discloses methods of making and uses for wide spectrum disinfectants including as components an alcohol, O-phenylphenol, chlorhexidine gluconate, nonoxynol-9, benzalkonium chloride, and deionised double distilled water wherein on a weight/volume ratio the alcohol comprises from 50 to 80%, the O-phenylphenol comprises from 0.1% to 0.8%, the chlorhexidine gluconate comprises from 0.01 to 1%, the nonoxynol-9 comprises from 0.02 to 1%, and the benzalkonium chloride comprises from 0.15 to 1%.

The invention provides pubes-cleaning disinfection nursing liquid used for the pudendum and the vagina of a human body, which consists of 'chlorhexidine acetate (or chlorhexidine gluconate), borneol and osthole' added with a proper amount of synergist and the balance of distilled water, wherein the pH value is adjusted to be 4 to 5 by a pH balance factor. The product can kill pathogenic bacteria of HIV, neisseria gonorrhoeae, staphylococcus aureus, escherichia coli, candida albicans and the like and other viruses in one minutes so as to block cross infections of various infectious diseases, eliminate smells and relieve itching.

The invention provides a multi-purpose disinfectant, which is mainly applied to skin, surfaces of the wound and mucous membranes, surfaces of common articles and textile, and the like. The disinfectant consists of the following raw materials: single and double chain compound quaternary ammonium salt, chlorhexidine acetat(or chlorhexidine gluconate) and proper amount of synergistic agent and distilled water. The disinfectant can quickly kill enteric bacilli, suppurative bacilli, yeast bacteria, hospital infection common bacteria, and all known common bacteria, and is widely applied to fields in medical treatment, industry, civilian use and the like.

The invention discloses chlorhexidine gluconate gargle, which contains the following components in part by weight: 0.08 to 1.2 parts of chlorhexidine gluconate, 50 to 100 parts of propylene glycol, 50 to 100 parts of glycerol and 1 to 5 parts of polyoxyethylene 40 hydrogenated castor oil. The chlorhexidine gluconate gargle has a simple formula, a simplified process and stable quality.

A non-toxic mucosal disinfectant for topical application in the nose has a composition of 91% isopropyl alcohol of at least 50% by weight; sesame oil not exceeding 45% by weight, lemon oil of about 2% by weight, aloe of about 5-10% by weight, and optional components of chlorhexidine gluconate and grapefruit seed extract. All of the components are mixed homogeneously, with the sesame oil supplementing and neutralizing the dehydrating effect of the alcohol.

A catheter configured for partial implantation into a patient and drainage of a body cavity may be provided with microtextured surface on one or more inner diameter surfaces and/or outer diameter surfaces of the tubular catheter body. The microtexturing may include surface features dimensioned to inhibit colonization and/or migration of microbes. The microtexturing may also include channels or other recesses containing an antimicrobial agent such as chlorhexidine gluconate or any other effective antimicrobial agent.

The invention discloses a wound antibiotic flushing fluid and a preparation method thereof. Counted by 100 ml of wound antibiotic flushing fluid, the the formula of the wound antibiotic flushing fluid comprises the following raw materials: 0.01-2 g of chlorhexidine salt, 3-1,000 micrograms of silver nitrate, 10-70ml of absolute ethyl alcohol, 5-20 ml of emollient, 0.5-5g of thickening agent, 0.05-5g of tween 80, 0.5-5g of pH adjusting agent and 20-90ml of deonized water, wherein the chlorhexidine salt is chlorhexidine acetate or chlorhexidine gluconate; and the emollient is glycerol. The preparation method comprises the following steps of: dissolving the thickening agent in the deonized water, then respectively adding the chlorhexidine salt, the silver nitrate, the absolute ethyl alcohol, the emollient, the tween 80 and the pH adjusting agent into the mixed solution and stirring for 30 minutes to 2 hours. The wound antibiotic flushing fluid contains various antibiotic components and considerably strong broad spectrum bacteriostasis and sterilization functions, can kill various bacterial and fungus and has constant antibacterial action.

Provided herein is a composition and a method for removing CHG from textiles. The composition is an acid-surfactant-based composition that may be used to remove CHG from a textile that has not been exposed to chlorine subsequent to being exposed to CHG.

A synergistic pharmaceutical composition for the preparation of topical formulations for use in prophylaxis and treatment of wounds, burn wounds, skin grafts, pressure ulcers, diabetic foot ulcers and other skin diseases is provided. The composition may include one or more synergistically active ingredients and one or more inactive ingredients. The synergistically active ingredients may include Recombinant Human Epidermal Growth Factor (rh-EGF) (REGEN-D™ of Bharat Biotech International Limited) and/or Platelet Derived Growth Factor (rh-PDGF-BB), silver sulfadiazine (SSD) and chlorhexidine gluconate (CHG). One or more inactive ingredients may comprise carriers, preservatives, emulsifiers, skin emollients and soothers and one or more other constituents.