This invention refers to long-lasting antibacterial compositions with a
broad spectrum of activity, including bactericidal, bacteriostatic, virucidal, virustatic, germicidal, algicidal, fungicidal, and fungistatic activities. These compositions can be used for the production of topical formulations or for environmental treatment, surface disinfection, or
dental use. The composition can be in the form of a solution, a moist gel, xerogel,
aerosol, spray, polymeric
system, or
solid state. Specifically, the invention refers to compositions, such as aqueous or alcoholic solutions, or even in gel or
powder form, with
antibacterial activity. These compositions contain a cationic active (
chlorhexidine digluconate,
quaternary ammonium, or cetil
pyridine) nanoencapsulated in
cyclodextrin (alpha-
cyclodextrin, beta-
cyclodextrin, gamma-cyclodextrin,
hydroxymethyl beta-cyclodextrin, or hydroxypropyl beta-cyclodextrin), which may optionally include
alkyl or
aryl group insertions, at a
molar ratio of 1:1 to 1:4. These compositions also include anionic excipients, as well as humectants, stabilizers, sequestering agents, surfactants, preservatives, or thickeners. Preferably, they include the anionic surfactant
sodium lauryl
sulfate or the anionic thickener carbomer.