26 results about "Bone dust" patented technology

The invention discloses a body temperature responsive wet adhesive as well as a preparation method and application thereof in bone defect repair, and belongs to the technical field of preparation of bone defect repair materials. Carbon-carbon double bonds in methoxyethyl acrylate (MEA), N-isopropylacrylamide (NIP) and acrylic acid (AA) are subjected to a free radical polymerization reaction to generate a polymer chain, and a cross-linking agent containing metal cations is added for cross-linking. The body temperature responsive wet adhesive has a good wet adhesion effect and the ability of improving the stability of bone meal, and can solve the technical problem of bone substitute displacement caused by unstable fixation of a barrier membrane.

1. The name of the design product: dental bone powder conveyor. 2. The use of the design product: bone powder conveyor for dental use. 3. The design features of the design product: in shape. 4. The picture or photo that best shows the design features: perspective view.

The invention discloses a digital auxiliary PRF bone meal complex preparation method applied to periodontal minimally invasive surgery, belongs to the technical field of PRF bone meal complex preparation, and overcomes the defects that in the prior art, PRF bone meal complex and minimally invasive surgery combination is ineffective, and MIST curative effect improvement is limited due to poor adaptability of bone grafting materials. The method comprises the following steps: constructing a matched three-dimensional oral cavity model according to multi-source oral cavity data of a patient; reconstructing and cutting the three-dimensional oral cavity model to obtain an operation area surface data model; performing optimization and manufacturing adaptation processing on the surface data model of the operation area to obtain a three-dimensional digital model of the subbony pocket form female die; according to the three-dimensional digital model, preparing a subosseous pocket form female die, and preparing the PRF bone powder complex matched with the subosseous pocket in the subosseous pocket form female die.

The invention discloses a traditional Chinese medicine ingredient modified bone graft material and a preparation method thereof, and relates to the technical field of bone graft materials. The feed additive is prepared from the following raw materials: calcined bone meal and a traditional Chinese medicine extract, the traditional Chinese medicine extract comprises a radix salviae miltiorrhizae extract and / or a radix scutellariae extract. The preparation method comprises the following steps: preparing calcined bone meal, preparing simulated body fluid and preparing the modified bone graft material. The product material can be applied to a dental bone grafting material. The traditional Chinese medicine extract is loaded on the bone material, and the bone material is modified, so that the bone graft material with good biocompatibility, osteogenesis promoting capability and better osteogenesis induction potential can be obtained.

The utility model relates to the technical field of bone fetchers, in particular to a bone fetcher for tooth implantation, which comprises a connecting rod, a clamping groove and a stop guide component, the clamping groove is arranged on the inner side of the connecting rod, the stop guide component is fixedly connected with the tail end of the lower side of the connecting rod and comprises a stop plate, and a clamping hole is arranged on the inner side of the stop plate. The guide limiting assembly comprises a clamping pin, a limiting clamping ring is fixedly connected to the tail end of the lower side of the clamping pin, a rubber ring is arranged on the inner side of the limiting clamping ring, a fixing rod is fixedly connected to the outer side of the lower end of the limiting clamping ring, and a guide limiting ring is fixedly connected to the tail end of the lower side of the fixing rod. According to the bone meal collecting and storing device, the device can adapt to work at different angles, the phenomenon of deviation and inclination of the stopping ring is avoided, the bone meal collecting and storing effect and the rotating performance of a drill bit are guaranteed, and therefore the efficiency and safety of a dental implant operation are improved.

The utility model discloses a 3D (three-dimensional) printing implant for oral implantation in the technical field of medical equipment, which comprises an implant structure, the implant structure comprises an implant body, the implant body is of a gradient pore net structure, a bioactive layer is arranged on the outer side of the implant body, and the bioactive layer is made of a transparent material. A bone meal attaching and guiding structure is arranged on the inner wall of a mesh hole of the implant body, a surface fixing structure is arranged on the surface of the implant body, and a bottom fixing structure is arranged at the bottom of the implant body. According to the utility model, the implant body is arranged into the net-shaped structure, and the bone meal attachment and guide structure is matched, so that the bone meal can be guided to directionally grow along the net-shaped pores, the traditional osteogenesis waiting stage is skipped, the implant implantation and bone increment are synchronously completed, and the damage to soft tissues caused by repeated bone meal filling and pressing operation is avoided.

The invention relates to the technical field of infusion bone repair materials, in particular to an infusion bone repair material and a production process thereof, the infusion bone repair material comprises alpha-calcium sulfate hemihydrate, allogeneic bone powder particles and a modified hyaluronic acid solution with the mass fraction of 2.5%; wherein the preparation process of the modified hyaluronic acid comprises the following steps: preparing methacrylated hyaluronic acid: stirring methacrylated hyaluronic acid and a poloxamer solution, and controlling the stirring time to be 10-30 minutes and the stirring temperature to be 20-25 DEG C, so as to obtain the poloxamer modified methacrylated hyaluronic acid; the preparation method comprises the following steps: carrying out reaction on poloxamer modified methacrylated hyaluronic acid and a solution of BMP-2-loaded mesoporous silica for 2 minutes under the condition of a rotating speed of 800 rpm to obtain modified hyaluronic acid; the infusible bone repair material has the effects of unification of high-strength support and low-resistance injection, matching of the material storage period and the osteogenesis process and bioactivity synergism.

The invention provides a preparation method and application of a digital plasma matrix bone block, and belongs to the technical field of medical materials. By combining a digital technology and a plasma matrix technology, the personalized plasma matrix bone block with regeneration activity and mechanical strength is immediately prepared in an operation according to the defect condition of a patient. Compared with a traditional bone regeneration scheme, the digital plasma matrix bone block can be shaped immediately in an operation and is matched with a defect area; in addition, the digital plasma matrix bone block has good mechanical strength, and the collapse problem after traditional bone meal transplantation or the exposure problem after a titanium mesh is applied can be avoided; more importantly, the digital plasma matrix bone block has good bone regeneration effects including bone conduction, bone induction, bone regeneration and the like. The digital plasma matrix bone block is more economical for a patient, is convenient for an operator to operate, has good biological safety, and provides a personalized solution for regeneration and repair of bone tissue defects.

The present invention provides a bone graft composite material and a manufacturing method therefor. The bone graft composite material is applied to wound repair of a user in orthopedic surgery and dental surgery, and is used to promote wound healing of the user, induce growth of an autologous bone cell of the user, and induce fusion of a transplanted bone of the user with the autologous bone cell. The bone graft composite material comprises a high molecular polymer, bone powder, and exosomes. Compared with the prior art, the bone graft composite material provided by the present invention has better osteoinductivity and compatibility, and can stably release biological factors, thereby promoting the repair and regeneration of bone.

The invention discloses a 3D printing photocuring bone repair membrane and a preparation method thereof, the bone repair membrane is formed by photocuring 3D printing of a photocuring resin composition, the thickness of the bone repair membrane is 0.1-0.3 mm, and the bone repair membrane has a three-dimensional communicated pore structure; the light-cured resin composition comprises macromolecular resin, a reactive diluent and a photoinitiator, the mass ratio of the macromolecular resin to the reactive diluent is (0.5-3): 1, and the mass of the photoinitiator is 0.1%-10% of the mass of the macromolecular resin. The 3D printing light-cured bone repair film is used in cooperation with bone meal with a bone wound surface filling effect, can be tightly attached to the surface of the bone wound surface filled with the bone meal, does not need to be sutured and fixed, and simplifies the clinical operation process, so that the barrier effect is achieved, and the secondary injury risk of the wound surface is reduced; the bone repair membrane has good biocompatibility, controllable degradability and a three-dimensional communicated pore structure, can be matched with the bone tissue regeneration rate, is high in process controllability, can precisely regulate and control the structure and performance, and meets the bone tissue repair requirement.

The application discloses a kind of bone ash-based dense ceramics and its preparation method, the ceramic raw material comprises the bone ash 80~92 parts after pre-burning treatment according to weight fraction, crystal powder 8~20 parts;The crystal powder is obtained by melting reaction of cremated bone ash or bone powder and phosphoric acid under high temperature condition, and the crystal block is obtained after cooling, and then the crystal block is ground into powder.The crystal powder is used as the liquid phase of bone ash-based dense ceramics, and the preparation process includes bone ash pre-burning treatment, crystal powder preparation, bone ash and the crystal powder are uniformly mixed according to a certain proportion, and the bone ash-based dense ceramics is obtained by sintering at 750~950 DEG C after polishing and sieving and preforming.

This invention discloses a method for expanding the volume of a composite matrix, an osteogenic composition, and its applications. The components of this invention are entirely autologous, posing no risk of immune rejection or disease transmission. The composite matrix in the osteogenic composition provides a bone conduction scaffold, while the volume-expanding agent provides bone-inducing signals while simultaneously expanding the composite matrix, thus providing a dual osteogenic mechanism. This invention requires only a conventional centrifuge and sterile containers, making it suitable for outpatient surgery. It also eliminates the need to purchase expensive bone powder, offering advantages such as ease of operation and low cost. Furthermore, the materials of this invention exhibit good stability; the composite matrix, after being encapsulated by the volume-expanding agent, does not easily dissipate and conforms well to the defect morphology.

1. The name of the design product: bone powder delivery device. 2. The use of the design product: for dental delivery of bone powder. 3. The design features of the design product: in shape. 4. The picture or photo that best shows the design features: perspective view.

The application relates to a transcrestal maxillary sinus bottom lifting auxiliary bone grafting device and a working method thereof, and belongs to the technical field of medical devices. The device comprises a flaring device and a fixer. The flaring device comprises a hollow cylinder, a conical block and a cylindrical filling block which are sequentially arranged from top to bottom, the flaring device is funnel-shaped as a whole, and the hollow cylinder is symmetrically provided with fixing holes. The fixer comprises a connecting column, a nut, a sliding block, a positioning protrusion, two first connecting rods and two second connecting rods. The connecting column is provided with a thread at one end, the thread is provided with the nut, the other end of the connecting column is hingedly connected with the two second connecting rods, the sliding block is slidably sleeved on the connecting column, the two first connecting rods are respectively hingedly connected to the two second connecting rods, and the two second connecting rods are respectively provided with the positioning protrusions at the ends. The application can fully expose the bone defect position, ensure the filling position accuracy of the bone powder filling device, conveniently observe the bone powder filling amount, and improve the bone powder filling effect.

The application relates to a preparation method of a self-barrier oral bone powder and the preparation method, and relates to the technical field of medical treatment. The problems that there is no adhesion between particles in the existing GBR operation, the particles are relatively dispersed, are easy to be displaced, need to be combined with an oral repair film for joint use, and the operation requirement of a doctor is relatively high are solved. The preparation method comprises the following steps: mixing and ball milling calcium phosphate salt powder and photosensitive resin according to a proportion, and forming a slurry after the ball milling; printing a plurality of independent particles with a straight-through hole structure from the slurry through 3D printing technology; calcining the printed particles; mixing and loading the calcined particles and calcium sulfate hemihydrate powder into a booster with a porous filter head according to a proportion; and adding a liquid medium into the booster and uniformly mixing, so that a paste-shaped composite material which can be pushed out is prepared; the paste-shaped composite material has the effects of self-curing, forming a hard inorganic substance which cannot be moved, can act as a barrier film, is beneficial to cell ingrowth, and reduces the operation difficulty.

This invention discloses an injectable bone powder with anti-inflammatory biological activity, its preparation method, and its application. The bone powder is a hydrogel internally loaded with a hydroxyapatite composite material, wherein the hydroxyapatite composite material is hydroxyapatite with membrane vesicles coated on its surface; the membrane vesicles are derived from pulp-derived suppressor cells; the mass-to-volume ratio of the hydroxyapatite composite material to the hydrogel is 20-30%. This injectable bone powder with anti-inflammatory biological activity, containing membrane vesicles derived from pulp-derived suppressor cells coated on the surface of the hydroxyapatite, has biological effects that inhibit T cell proliferation and macrophage differentiation into osteoclasts, thus blocking the inflammatory environment, suppressing the inflammatory response, and promoting alveolar bone repair and regeneration.

The utility model relates to the technical field of medical instruments, and provides a bone meal container for oral surgery, which comprises a body and a filter bowl, the body is provided with a cavity with an open top end, the side surface of the body is provided with a through groove, the through groove comprises a first groove section and a second groove section which are communicated with each other, the first groove section extends along the vertical direction and penetrates through the top surface of the body, and the second groove section extends along the vertical direction. The second groove section is located at the top end of the first groove section and extends in the circumferential direction of the body, the bottom wall face of the second groove section is located above the bottom wall face of the first groove section, the first groove section and the second groove section are both communicated with the containing cavity, the filter bowl is provided with filter holes allowing liquid to pass through, the filter bowl is used for containing bone meal, and a handle is arranged on one side of the filter bowl. The handle penetrates through the through groove, and one end of the handle is located on the outer side of the body. Therefore, bone meal soaked in normal saline does not need to be transferred into another container, and waste can be reduced.

The invention discloses an AI-assisted bone powder implant for alveolar bone repair. The AI-assisted bone powder implant comprises a biodegradable integrated composite stent, a micro sensing unit, a piezoelectric micro pump, a micro processing unit and a micro battery, the integrated composite scaffold is of a bionic heterostructure formed through 3D printing and sequentially comprises a cancellous bone layer, a cortical bone layer and a soft tissue layer from bottom to top. A reserved cavity in which the piezoelectric micro pump, the micro processing unit and the micro battery are embedded is formed in the cancellous bone layer; the micro sensing unit is integrally formed on the surface of the cancellous bone layer through 3D printing, and at least comprises a micro pH sensor and a piezoelectric impedance composite sensor; the micro processing unit receives signals of the micro sensing unit, the signals are processed by the trained AI analysis model, a control instruction is generated to drive the piezoelectric micro pump to release medicine according to needs, and the micro battery is used for supplying power. According to the method, active monitoring and active and self-adaptive repairing can be performed without external intervention, and the predictability and stability of repairing quality are remarkably improved.

The invention discloses a preparation method of an allogeneic bone shaping material, which comprises the following steps: S1, bone pretreatment to obtain freeze-dried bone powder and demineralized bone powder; s2, bone gelatin extraction; s3, preparing an excipient, wherein the bone gelatin in the step S2 is added into water containing polyvinylpyrrolidone to be swelled; and S4, mixing the freeze-dried bone powder and the demineralized bone powder in the step S1 with the excipient in the step S3 in proportion to obtain the allogeneic bone shaping material. According to the preparation method, polyvinylpyrrolidone is added, the proportion of freeze-dried bone powder to demineralized bone powder in the mixed bone powder is adjusted, the degradation rate of the allogeneic bone powder can be adjusted, and the allogeneic bone powder can be effectively degraded on the basis that good bone induction and bone conduction performance of the allogeneic bone powder is reserved. And the material is endowed with good injectability and plasticity.

The embodiment of the utility model provides an alveolar bone chipping drill for dental implant, which comprises a straight-rod-shaped handle part, a drill bit body is arranged at the front end of the handle part, and a connecting part matched with external dental handpiece equipment is arranged at the tail end of the handle part; the drill bit body comprises a first cutting part and a second cutting part; the first cutting part and the second cutting part are coaxial; and the cutting radius of the first cutting part is different from the small cutting radius of the second cutting part. According to the alveolar bone chip taking drill for the dental implant, the alveolar bone can be drilled into a shape which is close to an implant and similar to a cone through the first cutting part and the second cutting part which are different in radius, so that the implanting of the cone-shaped implant is facilitated, and the positioning effect of the positioning drill bit on the drill bit body is improved; the annular cutting drill body located on the periphery of the positioning drill bit can effectively guarantee center positioning. And bone scraps can be effectively collected through the bone scrap storage cavity, and bone scrap loss is avoided.

The invention discloses a tooth implantation bone powder filler for oral implantation, and relates to the technical field of medical instruments, the tooth implantation bone powder filler comprises a filling assembly, a storage assembly and an interception assembly; the filling assembly comprises a holding rod, a first magnet, a guide rod, a second magnet and an annular cylinder. The guide rod is fixed below the holding rod; a first magnet is fixed in the holding rod, and a second magnet is fixed in the guide rod. A ring cylinder is fixed outside the guide rod; the storage assembly comprises a material pipe, a sleeve, a third magnet and a fourth magnet. A magnet III and a magnet IV are respectively fixed on the side surfaces of the material pipe and the sleeve; the filling assembly can be reused after being disinfected, and only the material pipe and the sleeve which are in direct contact with bone meal are used as disposable consumables, so that the cost of long-term use is greatly reduced, and the device is more environment-friendly; the section of the storage groove and the section of the limiting groove are arc-shaped, the material pipe is made of a rubber material matched with the material pipe, and the arc-shaped design is more fit with the finger pulp, so that a doctor is stressed uniformly without dead angles during manual extrusion, and viscous dough-shaped bone meal can be almost extruded out completely.

The application discloses a bone powder refined spar and a preparation method and application thereof. The raw material of the spar comprises 1 part of bone powder, 1.5-4 parts of phosphoric acid with a mass fraction of 85%, 0.02-0.05 parts of boron trioxide and 0-0.001 parts of cerium nitrate; the bone powder is cremated bone ash or obtained by crushing and screening bone. The raw material is subjected to melting treatment at a temperature of 650-850 DEG C to form a wire-drawing clear melt, and the high-transparency spar with a smooth surface can be directly prepared after cooling and forming, without a reprocessing procedure such as surface grinding, and the spar is free of impurities in the inside, and has high aesthetic degree. In addition, the high-transparency spar can also be used as an adhesive for sintered dense ceramics.

This invention belongs to the field of reagent kit technology, specifically relating to a DNA extraction kit for bone samples. The kit includes a housing with a separation and stirring tank, a magnetic bead storage tank, and at least one liquid storage tank. A filter membrane is installed within the separation and stirring tank, dividing it into a first chamber and a second chamber, with the first chamber having a smaller space than the second chamber. This invention eliminates the need for centrifugation, directly separating bone powder and DNA for subsequent extraction steps. This not only avoids DNA loss caused by centrifugation but also shortens operation time, facilitates automation, simplifies the operation, and reduces the risk of sample contamination.

The application provides a bioactive bone powder conveying method and a bioactive bone powder conveyor, relates to the technical field of bioactive bone powder conveying, and synchronously collects bone powder micro-flow data and patient physiological parameters in a starting stage, and establishes a dynamic characteristic model; in continuous conveying, microstructure arrays and multiple sensors perceive changes in bone powder fluid dynamics, optical / electrical characteristics, and acquire characteristic data. The characteristic data are matched with the model, an active state is judged according to a deviation, and a matched protection mode is triggered when the activity decreases. The application dynamically monitors the inherent characteristics of bone powder, early warns and intervenes in activity damage, and ensures the biological function of bone powder, so that the problem that the bioactivity of bioactive bone powder decreases slowly in the conveying process due to accumulation on the inner wall of a pipeline, increased shear force and increased local temperature, and the problem that the bioactivity is difficult to be detected through conventional monitoring means are effectively solved.

To provide a method for producing a hydraulic molded body, capable of obtaining excellent strength even when a bone powder content is increased.SOLUTION: A hydraulic composition containing Portland cement and bone powder, wherein a content of the bone powder excluding water is 30 to 60 wt.%, is placed into a mold, cured, and demolded to take out a hydraulic molded body. The content of the bone powder is 40 to 150 pts.mass. with respect to 100 pts.mass. of Portland cement. Accordingly, a bone Buddha statue having a high bone powder content and excellent strength can be obtained.SELECTED DRAWING: Figure 1

The invention provides a bone meal biological 3D printing device and method, and belongs to the field of medical 3D printing. Comprising a mixing printing module installed on a Z-axis module, and the module is formed by integrating a double-material pushing module, a double-material mixing and stirring module and a three-stage temperature control module. The double-material pushing module adopts a transmission unit and an extrusion unit which are bilaterally symmetrical, and the extrusion ratio of two bone meal materials is adjusted by independently controlling a first driving device; the double-material mixing and stirring module comprises a charging barrel unit, a mixing chamber and a stirring system, a charging barrel is communicated with the mixing chamber through a connecting pipeline, and a mixing chamber temperature control cabin is arranged outside the mixing chamber for heat preservation to ensure that materials are output after being uniformly mixed; and the three-stage temperature control module performs independent temperature adjustment on the charging barrel and the mixing chamber to prevent the material from being solidified. During working, the proportion of bone meal materials is adjusted by controlling the driving device, the materials are extruded and printed after being stirred in the mixing chamber, precise bone repair manufacturing is achieved, and technical guarantee is provided for personalized customization and precise medical treatment of the bone repair materials.